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- 저자 : Jha, Ajit Kumar (검색결과 314 건)
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J. HA,허훈,J. H. SONG,J. H. LIM 한국자동차공학회 2013 International journal of automotive technology Vol.14 No.1
This paper proposes a new equivalent failure strength model for spot welds under combined axial and shear loading. To evaluate the pure-shear strength of spot welds fabricated under the same welding conditions with a two-layered lap joint, a test fixture and a specimen were newly designed and proposed. The failure tests of spot welds of TRIP590 1.2t,DP780 1.0t, DP780 1.2t, and DP980 1.2t were carried out at seven different loading angles ranging from 0o to 90o at an internal angle of 15o to obtain the failure loads. The failure loads obtained from the experiments were utilized to construct the failure criterion and thus describe the failure behavior of spot welds in the crash analysis or strength analysis of an auto-body. It is noted that the value of β in the failure criterion for spot welds of AHSS is different from the values of conventional steels. The new equivalent failure strength model proposed in this paper was derived from the failure test results to provide a representative failure model that can be used to accurately compare the failure characteristics of different materials under the same conditions.
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DRAG REDUCTION OF A PICKUP TRUCK BY A REAR DOWNWARD FLAP
J. HA,S. JEONG,S. OBAYASHI 한국자동차공학회 2011 International journal of automotive technology Vol.12 No.3
The drag reduction of a pickup truck by a rear flap add-on was examined through CFD simulations and wind tunnel experiments. When installed at the rear edge of the roof, the flap increased the cabin back surface pressure coefficient, causing the downwash of the bed flow to be inclined on the tailgate. Thus, the attachment of the bed flow to the tailgate was eliminated; consequently, the drag coefficient was reduced with increasing flap length and downward angle despite the enlarged reverse flow in the wake. However, the drag coefficient did not decrease any further after a specific downward angle was reached because the bed flow increased the drag force at the tailgate and the flap lowered the pressure field above the flap. To maximize the drag reduction effect, the rear downward flap should be designed to have an optimum downward angle.
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정신분열병 환자의 임상반응에 따른 혈장 Homovanillic Acid와 혈장 할로페리돌의 변화
구자일,오동열,양병환 大韓神經精神醫學會 1992 신경정신의학 Vol.31 No.1
Nineschizophrenic inpatients were studied under halopendol treatment for the purpose of evaluating the possible correlation between plasma HVA, leuels(P-HVA) plasma halopendol levels (P-haloperidal) and clinical symptom changes. The authors measured plasma HVA and plasma haloperidol levels, and checked BPRS and SAPS scores at baseline, 7th day. 28th day and 56th day of treatment. 1) P-HVA concentrations of total patients were highest on 7th day, then returned to baseline levels on 28th day. but that of drug responder group(6 patients) were highest on pretreatment then decreased below baseline levels on 7th day and continued to decrease till 56th day of treatment. 2) P-HVA concentrations of total patients showed positive correlations with BPRS scores (r=0.28, p<0.l) and-with SAPS scores(r=0.36, p<0.05) and that of drug responder group showed also positive correlations with BPRS scores(r=0.24, p=NS) and with SAPS scores (r=0.45. p<0.0l). 3) P-haloperidol concentrations of total patients showed significant positive correlation with haloperidol doses(r=0.73, p<0.00l) and that of drug responder group showed positive correlation with haloperidol doses(r=0.53. P<0.01). P-haloperidol concentration of drug responder group showed significant negative correlation with BPRS scores(-0.72, P<0.01) and with SAPS scores(-0.59. P<0.001) but that of total patients did not. 4) The haloperidol doses of drug responder group showed meaningful negative correlations with P-HVA(r=-0.38. p=0.03) and with BPRS scores (r=-0.50. P<0.01) and with SAPS scores(r=-0.47. p=0.0l) but that of total patients did not. The authors discussed the meaning of above results.
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Pankaj Kumar Jha,Saroj Sapkota,Neena Amatya Gorkhali,Bhoj Raj Pokharel,Ajeet Kumar Jha,Shishir Bhandari,Bhola Shankar Shrestha 사단법인 한국동물생명공학회 2019 한국동물생명공학회지 Vol.34 No.4
The study was conducted to evaluate the seminal attributes and cryo-banking of Achhami (Bos indicus) bull semen. Of two Achhami bulls, 8 ejaculates from each bull were evaluated for seminal attributes. For semen freezing and cryo-banking, 4 ejaculates (having ≥2 mL semen volume, ≥75% of sperm motility and ≥1,000 × 106 cells/mL of sperm concentration) from each bull were used. Semen samples were diluted in egg-yolk-tris-citrate extender using a two-step dilution protocol, and were frozen in liquid nitrogen (LN2) vapour in a styrofoam box. The mean semen volume, colour, sperm mass activity, motility, viability, concentration, abnormal acrosome, midpiece and tail and, abnormal head of two Achhami bulls were 4.4 ± 0.5 mL vs. 2.5 ± 0.2 mL, 2.5 ± 0.1 vs. 2.4 ± 0.1, 3.5 ± 0.1 vs. 3.5 ± 0.1, 77.0 ± 1.1% vs. 78.3 ± 1.3%, 94.4 ± 0.5% vs. 91.0 ± 0.6%, 1137.7 ± 73.7 × 106 cells/mL vs. 1060.0 ± 44.3 × 106 cells/mL, 10.2 ± 0.5% vs. 10.3 ± 0.5% and 6.7 ± 0.5% vs. 8.2 ± 0.3%, respectively. The post-thawed sperm motility and viability were 53.0 ± 2.0% vs. 50.0 ± 0.0% and 80.2 ± 0.4% vs. 73.2 ± 0.7%, while evaluating by computer-assisted sperm analysis (CASA) system, the percentage of the progressive motility, fast motility, slow motility, local motility and immotile sperm were 75%, 68%, 7.4%, 16.6% and 8.6%, respectively. A total number of 620 doses semen straw were cryo-banked. Due to the acceptable post-thawed sperm motility and viability recorded, cryopreservation of Achhami semen is hereby recommended so as to preserve the Achhami breed. For further validation, the fertility will be observed from the produced frozen semen.
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Pankaj Kumar Jha,Saroj Sapkota,Neena Amatya Gorkhali,Bhoj Raj Pokharel,Ajeet Kumar Jha,Shishir Bhandari,Bhola Shankar Shrestha 한국동물생명공학회(구 한국동물번식학회) 2019 Journal of Animal Reproduction and Biotechnology Vol.34 No.4
The study was conducted to evaluate the seminal attributes and cryo-banking of Achhami (Bos indicus) bull semen. Of two Achhami bulls, 8 ejaculates from each bull were evaluated for seminal attributes. For semen freezing and cryo-banking, 4 ejaculates (having ≥2 mL semen volume, ≥75% of sperm motility and ≥1,000 × 106 cells/mL of sperm concentration) from each bull were used. Semen samples were diluted in egg-yolk-tris-citrate extender using a two-step dilution protocol, and were frozen in liquid nitrogen (LN2) vapour in a styrofoam box. The mean semen volume, colour, sperm mass activity, motility, viability, concentration, abnormal acrosome, midpiece and tail and, abnormal head of two Achhami bulls were 4.4 ± 0.5 mL vs. 2.5 ± 0.2 mL, 2.5 ± 0.1 vs. 2.4 ± 0.1, 3.5 ± 0.1 vs. 3.5 ± 0.1, 77.0 ± 1.1% vs. 78.3 ± 1.3%, 94.4 ± 0.5% vs. 91.0 ± 0.6%, 1137.7 ± 73.7 × 106 cells/mL vs. 1060.0 ± 44.3 × 106 cells/mL, 10.2 ± 0.5% vs. 10.3 ± 0.5% and 6.7 ± 0.5% vs. 8.2 ± 0.3%, respectively. The post-thawed sperm motility and viability were 53.0 ± 2.0% vs. 50.0 ± 0.0% and 80.2 ± 0.4% vs. 73.2 ± 0.7%, while evaluating by computer-assisted sperm analysis (CASA) system, the percentage of the progressive motility, fast motility, slow motility, local motility and immotile sperm were 75%, 68%, 7.4%, 16.6% and 8.6%, respectively. A total number of 620 doses semen straw were cryo-banked. Due to the acceptable post-thawed sperm motility and viability recorded, cryopreservation of Achhami semen is hereby recommended so as to preserve the Achhami breed. For further validation, the fertility will be observed from the produced frozen semen.
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Priyanka A. Jha,A.K. Jha 한국물리학회 2013 Current Applied Physics Vol.13 No.7
In the present study, structural, dielectric and ferroelectric properties of Ba1-3x/2Yx Zr0.025Ti0.975O3ferroelectric ceramics have been investigated. The compound was synthesized using solid state reaction technique. The effect of yttrium substitution on structural, dielectric and ferroelectric properties was studied using X-ray diffractometer, scanning electron microscopy (SEM), LCR meter and PeE loops. Phase analysis shows the formation of secondary phase YTi2O6 for Y ≥ 2.5 mol% substitution. The microstructural investigation shows that Y substitution significantly reduces the grain size. An increase in Y content up to 2.5 mol% increases the Curie temperature (Tc) initially but decreases subsequently. The maximum dielectric constant at Tc has been observed for 2 mol% Y substitution and with further increase in Y content the dielectric constant decreases considerably. The solubility limit is found to be 2.5 mol% of Y and after that some of the yttrium atoms enter B-sites and leading to the formation of the secondary phase. The PeE loop studies show that there is an increase in the coercive field with increasing Y content.
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Jha, Amit Kumar,Pokhrel, Anaya Raj,Chaudhary, Amit Kumar,Park, Seong-Whan,Cho, Wan Je,Sohng, Jae Kyung Korean Society for Molecular and Cellular Biology 2014 Molecules and cells Vol.37 No.10
Spinosyns A and D are potent ingredient for insect control with exceptional safety to non-target organisms. It consists of a 21-carbon tetracyclic lactone with forosamine and tri-Omethylated rhamnose which are derived from S-adenosyl-methionine. Although previous studies have revealed the involvement of metK1 (S-adenosylmethionine synthetase), rmbA (glucose-1-phosphate thymidylyltransferase), and rmbB (TDP-D-glucose-4, 6-dehydratase) in the biosynthesis of spinosad, expression of these genes into rational screened Saccharopolyspora spinosa (S. spinosa MUV) has not been elucidated till date. In the present study, S. spinosa MUV was developed to utilize for metabolic engineering. The yield of spinosyns A and D in S. spinosa MUV was $244mgL^{-1}$ and $129mgL^{-1}$, which was 4.88-fold and 4.77-fold higher than that in the wild-type ($50mgL^{-1}$ and $27mgL^{-1}$), respectively. To achieve the better production; positive regulator metK1-sp, rmbA and rmbB genes from Streptomyces peucetius, were expressed and co-expressed in S. spinosa MUV under the control of strong $ermE^*$ promoter, using an integration vector pSET152 and expression vector pIBR25, respectively. Here-with, the genetically engineered strain of S. spinosa MUV, produce spinosyns A and D up to $372/217mgL^{-1}$ that is 7.44/8.03-fold greater than that of wild type. This result demonstrates the use of metabolic engineering on rationally developed high producing natural variants for the production.
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In vitro morphogenesis in Selaginella microphylla (Kunth.) Spring
Jha, Timir Baran,Mukherjee, Siddhartha,Basak, Anusuya,Adhikari, Jukta 한국식물생명공학회 2013 Plant biotechnology reports Vol.7 No.3
Selaginella, an extant genus of primitive vascular plants, has survived over 400 million years of evolution. In vitro morphogenesis in Selaginella microphylla is considered for the first time to establish a well-documented aseptic culture on half- strength Murashige and Skoog's basal medium with 2ip ($4.92-49.21{\mu}M$), or Kn ($4.65-46.47{\mu}M$) or $GA_3$ ($2.89-28.90{\mu}M$) for shoot multiplication, and with different concentrations of IBA (4.9-49 lm) to initiate root cultures. $GA_3$ was instrumental for shoot multiplication as well as induction of reproductive structures in each and every leaf axil. On the other hand, it is observed that IBA alone in S. microphylla can act as signal molecules for induction of enormous numbers of root masses from a few existing roots. An interesting pattern of re-differentiation has also been observed where apical portions of large numbers of roots were converted to green shoot apical meristems. Further differentiation produced tiny green shoots. Distinct bipolarity was noted in shoots when they were isolated from root masses and appeared as embryo-like structures. Chromosome analysis from in vitro sporophytic plants revealed 2n = 16 chromosomes, indicating chromosomal stability. The interesting in vitro pattern of morphogenesis obtained in S. microphylla may provide new insights into totipotency of plants.
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A New Method for Reconstruction of Smooth Branching Surface from Contours
Jha, Kailash Society for Computational Design and Engineering 2012 International Journal of CAD/CAM Vol.12 No.1
A new algorithm has been developed to construct surface from the contours having branches and the final smooth surface is obtained by the reversible Catmull-Clark subdivision. In branching, a particular layer has more than one contour that correspond with at least one contour at the adjacent layer. In the next step, three-dimensional composite curve is constructed from contours of a layer having correspondence with at least one contour at the adjacent layer by inserting points between them and joining the contours. The points are inserted in such a way that the geometric center of the contours should merge at the center of the contours at the adjacent layer. This process is repeated for all layers having branching problems. Polyhedra are constructed in the next step with the help of composite curves and the contours at adjacent layer. The required smooth surface is obtained in the proposed work by providing the level of smoothness.
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Jha, Dipendra Kumar,Mittal, Ankush,Gupta, Satrudhan Pd,Sathian, Brijesh Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.7
Background: The present study was undertaken to establish any correlation of elevated levels of CA19-9 with tumor stage or grade of urothelial carcinoma. Materials and Methods: This hospital based study was carried out in the Department of Biochemistry of Nepalese Army Institute of Health Sciences between $1^{st}$ July 2012 and $31^{st}$ December 2012. Approval for the study was obtained from the institutional research ethical committee. CA19-9 was assayed with an ELISA reader for all cases and expressed in U/ml with 37U/ml taken as the cut-off upper value for normal. Results: Out of 20 cases enrolled, 15 were of urothelial carcinoma and the remaining 5 were controls. There was marked difference between the mean values of CA19-9 in cases $40.2{\pm}19.3U/ml$ of urothelial carcinoma and controls $7.98{\pm}7.34U/ml$. The number of cases in Ta, TI, T2, T3, T4 stages of urothelial carcinoma were 2, 6, 3, 3, 1 respectively. The percentage rise in CA19-9 was less with low grade tumors (22.2%) when compared with high grade tumors (66.6%) (p value $0.001^*$). The percentage of rise in CA19-9 for muscle invasive tumors was very high when compared to superficial tumors. Similarly, the percentage of rise in CA19-9 for metastatic disease was very high when compared to non-metastatic disease and it was found statistically significant (p value $0.001^*$). Conclusion: Serum CA19-9 levels predicts the prognosis of urothelial carcinoma as it is almost invariably raised in tumors having metastatic spread.
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