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RISS 인기검색어
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- 저자 : Jeffrey CY Chan (검색결과 1 건)
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Jeffrey CY Chan,John Ward,Fabio Quondamatteo,Peter Dockery,John L Kelly 대한성형외과학회 2014 Archives of Plastic Surgery Vol.41 No.6
Background: The depth of graft harvest and the residual dermis available for reepithelizationprimarily influence the healing of split-skin graft donor sites. When the thigh region ischosen, the authors hypothesize based on thickness measurements that the anterolateralregion is the optimal donor site. Methods: Full-thickness skin specimens were sampled from the anteromedial, anterior, andanterolateral regions of human cadavers. Skin specimens were cut perpendicularly with acustom-made precision apparatus to avoid the overestimation of thickness measurements. The combined epidermal and dermal thicknesses (overall skin thickness) were measured usinga digital calliper. The specimens were histologically stained to visualize their basementmembrane, and microscopy images were captured. Since the epidermal thickness varies acrossthe specimen, a stereological method was used to eliminate observer bias. Results: Epidermal thickness represented 2.5% to 9.9% of the overall skin thickness. There wasa significant difference in epidermal thickness from one region to another (P<0.05). Theanterolateral thigh region had the most consistent and highest mean epidermal thickness(60±3.2 μm). We observed that overall skin thickness increased laterally from the anteromedialregion to the anterior and anterolateral regions of the thigh. The overall skin thicknessmeasured 1,032±435 μm in the anteromedial region compared to 1,220±257 μm in theanterolateral region. Conclusions: Based on skin thickness measurements, the anterolateral thigh had the thickestepidermal and dermal layers. We suggest that the anterolateral thigh region is the optimaldonor site for split-skin graft harvests from the thigh.
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