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      • Parameter Identification of an Unknown Object in Human-Robot Collaborative Manipulation

        Jayoung Jang,Jong Hyeon Park 제어로봇시스템학회 2020 제어로봇시스템학회 국제학술대회 논문집 Vol.2020 No.10

        In human-robot collaborative manipulation of an object, if the robot knows the intention of the human, the efficiency of the work would greatly increase. For the robot to know of the human intention, it should have the information of the force applied by the human, which can be more accurately if it can estimate the inertial and dimensional parameters online. However, the force applied by the human will disturb the parameter identification process. This paper presents a strategy to identify the inertial and dimensional parameters of an unknown object online for physical human-robot interactions. Extended Kalman filter is used for identification under the assumption that the force applied by the human is an unknown external disturbance. This approach was evaluated in simulations of physical human-robot object manipulation task.

      • KCI등재후보

        Safety Evaluation of Bilateral Same-day Intravitreal Ranibizumab Injections

        Jayoung Ahn,Kyu Hwan Jang,Joon Hong Sohn,Daniel Duck-Jin Hwang 대한검안학회 2020 Annals of optometry and contact lens Vol.19 No.3

        Purpose: This study aimed to evaluate the safety of bilateral same-day intravitreal ranibizumab injections by analyzing ophthalmic complications. Methods: Medical records of patients who underwent bilateral same-day intravitreal ranibizumab injections between January 2016 and December 2018 were retrospectively reviewed. Patient follow-up visits occurred 1 day, 1 month, and 2 months after the injections. Results: The study included a total of 31 patients, 62 eyes, and 148 bilateral same-day intravitreal ranibizumab injections. The most frequent cause for treatment was exudative age-related macular degeneration, totaling 126 injections (85.1%). Diabetic macular edema accounted for 20 injections (13.5%), and macular edema due to retinal vein occlusion accounted for two injections (1.4%). There were no cases of endophthalmitis, retinal detachment, or vitreous hemorrhage in any patient. We observed five eyes (3.38%) with sterile inflammation, of which three improved without any treatment. The remaining two eyes were in a single patient, and the inflammation improved after four days of treatment. Four eyes (2.7%) exhibited vitreous floaters, and subconjunctival hemorrhage was observed in five eyes (3.38%). Conclusions: The ocular complication rate of bilateral same-day intravitreal ranibizumab injection procedure was low.

      • Rapid determination of cholesterol in emulsified confectioneries by ultra‐performance liquid chromatography

        Ahn, Jang,Hyuk,Jeong, In‐,Seek,Kwak, Byung‐,Man,Leem, Donggil,Yoon, Taehyung,Yoon, Changyong,Jeong, Jayoung,Park, Jung‐,Min,Kim, Jin‐,Man WILEY‐VCH Verlag 2012 European journal of lipid science and technology Vol.114 No.11

        <P><B>Abstract</B></P><P>We developed a sample preparation method by using no‐heating saponification after dispersive SPE and ultra‐performance liquid chromatography for rapid determination of cholesterol in emulsified foods, such as cream pie, cream sandwich‐type biscuit, plate chocolate, and chocobar. Optimum cholesterol extraction was obtained by using 10 mL isopropyl alcohol and 8.0 g (NH<SUB>4</SUB>)<SUB>2</SUB>SO<SUB>4</SUB> per 1–2 g sample; saponification after extraction was performed using 25 mg KOH, 0.8 g NaCl, and 100 mg of a silica based NH<SUB>2</SUB> SPE material. The determined cholesterol concentration was within certified reference material limits, and results of the recovery test were in the range of 97.4 to 104.8% with a relative standard deviation between 2.14 and 3.80%. Since our method had less sample preparation and chromatographic separation times, we expect our method to be used for effective quality control processes for monitoring cholesterol concentrations in confectioneries.</P><P><B>Practical applications:</B> A rapid analytical method for determining the cholesterol concentration in emulsified confectioneries was developed by using UPLC. The assessed cholesterol levels after comparing them with the CRMs were within the permissible range; results of the recovery tests performed using spiked materials ranged from 97.4 to 104.8% with RSD between 2.14 and 3.80%. Thus, our method could be used for accurate and precise determination of cholesterol concentration at low analysis and pretreatment time.</P>

      • KCI등재

        기프트카드와 현금 지불에 따른 쾌락재 및 실용재에 대한 구매의도차이 분석: 긍정적,부정적 구매 감정의 매개효과를 중심으로

        장은영 ( Eunyoung Jang ),최자영 ( Jayoung Choi ) 한국소비자학회 2015 소비자학연구 Vol.26 No.5

        기프트카드는 편리한 선물 대안이자 유용한 지불수단이다. 이런 편의성 때문에 스타벅스 같은 커피 매장부터 구글 플레이 같은 온라인 몰, 그리고 각종 백화점 및 은행 등에서 기프트카드를 적극 출시하고 있다. 그런데 과연 이러한 기프트카드 이용은 단순히 지불수단의 확대와 구매방식의 편리성 향상 같은 의미만을 가지고 있을까? 심적회계이론(mental accounting theory)에 따르면, 소비자는 자기만의 심적 회계장부를 가지고 있어, 동일한 경제적 가치를 가진 재화일지라도 이를 서로 다른 심적회계로 분류하여 구매 결정하는 경향이 있다. 현금과 기프트카드를 똑같이 선물로 받았더라도 소비자들의 심적회계에서는 분리된 계정으로 인식될 수 있다는 것이다. 따라서 본 연구는 이러한 심적회계이론을 바탕으로, 기프트카드와 현금으로 구매할 경우, 제품 유형 별(쾌락재 vs. 실용재) 구매의도에 차이가 있는지를 분석하고자 하였다. 또한 사람들은 제품을 구매하면서의 즐거움과 동시에 지불 과정에서 고통을 느끼는데 어떤 지불수단을 사용하느냐에 따라 소비자의 구매감정이 다를 것으로 보고 감정의 차이를 분석하고자 하였다. 본 연구의 주요 목적은 지불수단(기프트카드 vs. 현금)에 따라 선호하는 제품의 유형과 구매감정에 차이가 있는지를 분석하고, 이러한 지불수단에 따른 제품유형별 구매의도의 차이가 감정 매개의 메커니즘을 통해 나타나는 것인지를 분석하는 것이다. 가설 검증을 위해 2(지불수단: 기프트카드 vs. 현금) x 2(제품 유형: 쾌락재 vs. 실용재) 집단 간 실험 설계를 하였으며, 20~40대 여성 183명을 대상으로 데이터를 수집하였다. 분석결과, 실용재에서는 지불수단(현금 vs. 기프트카드)에 따른 구매의도의 차이가 없었으나, 쾌락재에서는 현금으로 구매할 때보다 기프트카드로 구매하는 상황일 때 더 높은 구매의도를 보였다. 또한 지불수단에 따른 제품 유형별 감정의 차이를 분석한 결과, 쾌락재 구매 시 현금보다 기프트카드로 구매할 때 더 강한 ‘즐거움’과 ‘만족감’을 느끼는 반면, ‘죄책감’과 ‘불만족감’은 덜 느끼는 것으로 나타났으며, 이러한 감정은 지불수단별 선호제품의 차이를 매개하는 것으로 분석되었다. 쾌락재 구매에 대하여 현금은 긍정적 감정의 약화와 부정적 감정의 강화를 매개로 구매의도를 낮추지만, 기프트카드는 긍정적 감정의 강화를 매개로 구매의도를 높이는 것으로 분석되었다. 결론적으로, 본 연구는 기프트카드 이용이 단순히 구매 편의를 높이는 것 외에 쾌락재 구매를 증대시키는 유용한 마케팅 전략이 될 수 있음을 시사하며, 심적회계이론을 기반으로 감정메커니즘 차원에서 기프트카드와 쾌락재 구매 간의 관계를 분석하였다. This study shows how gift card and cash gift can affect the purchase intention of hedonic and utilitarian products through both of positive and negative purchase emotion. Mental accounting theory suggests that consumers tend to categorize and label their budgets into different psychological accounts depending on how the budget was acquired and the category to which it is assigned(Thaler 1980). Based on prior research, we think that gift card and cash gift will not be allocated into same account, and consumers tend to perceive two payment types as different monetary value. Compared to cash, gift cards are easier to justify to use and has a stronger association with gift and bonus meaning(Helion & Gilovich 2014; White 2006). Therefore, we hypothesize that gift card will be more likely to be spent on hedonic products than cash, but there is no difference between payment types on utilitarian products because unlike hedonic product, utilitarian product requires less justification by payment. Furthermore, we also predict that purchasing emotion will be different depending on the type of payment(gift card vs. cash) and product(hedonic vs. utilitarian). This is because the purchase of hedonic products tends to entail both of higher negative emotion such as guilty and higher positive emotion such as exciting than utilitarian, but gift card which is weakly associated with pain of payment can attenuate the negative feeling in hedonic product. Thus, we propose that in purchasing hedonic product condition, gift card use will lead to higher positive and lower negative purchasing emotion than cash, thereby such purchasing emotion mediates the effect of interaction of payment type and purchase type on purchase intention. We conducted an experiment with 183 women consumers(aged 20~40). The study employed a 2(payment: gift card vs. cash) x 2(product: hedonic vs. utilitarian) between-subject design. For testing hypothesis, ANOVA analysis was conducted where dependent variables were product purchase intention and negative/positive purchase emotion. The statistical results reveal that in the hedonic product purchase condition, consumers with gift card showed a higher purchase intention than those with cash, but in the utilitarian product purchase condition, there was no significant difference in purchase intention between gift card and cash. In addition, when people purchase the hedonic product with gift card, they reported higher positive purchase emotion(joy and contented) and lower negative purchase emotion(guilty and discontented) than those with cash. In contrast, when purchasing the utilitarian product, there was no significant difference in positive and negative purchase emotion between payment types. Finally, in order to verify the moderated mediation effect of emotion, PROCESS Model analysis(Hayes 2012) was conducted. As a result, we found out that the interaction effect of product type and payment type on purchase intention was mediated by positive and negative purchase emotion. Specifically, when purchasing hedonic products, cash decreased purchase intention through the mediation effect of lower positive and higher negative purchase intention. And gift card increased purchase intention of hedonic products through the mediation effect of higher positive purchase emotion. These result indicates that gift card and cash formats differently influence the consumer’s purchasing intention for hedonic and utilitarian products. From this results, our study practically suggests that companies will reap benefit from the gift card strategy since it can increase the sales of hedonic product by allowing consumers to feel higher positive emotion and reduced negative emotion.

      • KCI등재

        개방형 기프트카드의 딜레마: 폐쇄형 vs. 개방형 기프트카드에 따른 이용자의 선택 후 만족과 행복의 차이 분석

        최자영 ( Choi Jayoung ),장은영 ( Jang Eunyoung ) 한국소비자학회 2016 소비자학연구 Vol.27 No.5

        기프트카드는 크게 2가지 유형(개방형 vs. 폐쇄형)으로 구분해볼 수 있다. 이 중, 개방형(unrestricted) 기프트카드는 백화점, 은행/카드사 기프트카드와 같이 이용처가 폭넓은 기프트카드를 의미하며, 폐쇄형(restricted) 기프트카드는 특정 브랜드 업체에서만 사용 가능하여 제한성이 높은 기프트카드를 의미한다. 일반적으로, 선물을 주는 사람들은 폐쇄형 기프트카드보다는 이용 범위가 넓어 다양한 대안 중에서 선택할 수 있는 개방형 기프트카드를 주로 선물하고, 이러한 선택 자율성이 높은 개방형 기프트카드가 받는 사람에게도 더 큰 만족감과 행복감을 제공할 것으로 생각한다. 하지만 선택 대안이 넓은 경우, 소비자들은 오히려 선택 정당화가 어려워 선택 후 만족감이 감소하는 경향이 있다. 이와 마찬가지로, 선택 대안이 넓은 개방형 기프트카드가 인기는 있지만 실질적으로 선물을 받아 상품을 구매하는 사람의 입장에서는 오히려 폐쇄형 기프트카드가 더 큰 선택 후 만족감, 행복감을 느낄 수 있다. 분석결과, 기프트카드를 선물 받아 이용하는 사람들은 개방형 기프트카드보다는 폐쇄형 기프트카드로 상품을 선택할 때 선택 후 만족감과 행복감이 더 높은 것으로 나타났다. 특히 구매의 정당화가 더 크게 요구되는 쾌락재를 구매할 때, 개방형 보다 폐쇄형 기프트카드가 더 높은 만족감과 행복감을 느끼도록 하였으며 구매 정당화의 필요성이 낮은 실용재는 이러한 기프트카드 유형에 따른 차이는 없는 것으로 나타났다. 또한 쾌락재를 중심으로 정당화 용이성의 매개를 검증한 결과, 쾌락재 구매 상황일 때 폐쇄형 기프트카드는 선택의 정당화를 더 용이하도록 하여 선택 후 만족감과 행복감을 높이는 매개 효과가 있는 것으로 분석되었다. 최종적으로, 본 연구는 기프트카드 사용이 점점 늘어나고 있는 현 시점에서 소비자에게 더 큰 행복감과 만족감을 제공하기 위해 기업에서는 어떻게 기프트카드를 활용해야 하는가에 대해 실무적 시사점을 제공하고, 학술적으로도 기프트카드 지불수단에 대한 소비자의 선택후 행동의 차이와 매개 효과를 제시함으로써 시사점을 제공하고자 한다. This article examines how a gift card type(unrestricted vs. restricted) influences a gift-receiver`s choice satisfaction and happiness. Unrestricted gift cards mean the open-use gift card which can be used for almost every retailor stores like Amex and Visa gift cards, whereas restricted gift cards mean the closed-use gift cards which can only be used in particular stores from issuing retailers such as Starbucks and CGV gift cards(Reinholtz, Bartels, and Parker 2015). Generally, people tend to give unrestricted gift cards more often as a present since these cards can be used in broad retailer stores, thereby allowing gift-receivers to be able to purchase products in large assortments with choice diversity. However, this research casts a doubt on whether the unrestricted-gift cards would lead gift- receivers to higher satisfaction and happiness than restricted gift cards after choosing the product with the given gift cards. Although unrestricted gift cards provide choice diversity, such a broad choice assortment and diversity can cause the choice difficulty and complexity. Prior research has suggested that consumers are likely to feel lower satisfaction and have less positive choice attitude with large assortment rather than small assortment because large assortment can make choice justification difficult. Similarly, unrestricted gift cards which can be used in broad retailer stores can lower the choice satisfaction and happiness than restricted gift cards because compared to restricted gift cards, unrestricted gift cards allow receivers to considers more choice options from different retailers and this large assortment can cause negative effect on gift-receiver`s choice satisfaction and happiness. Thus, it is hypothesized that consumers with restricted gift cards will have higher choice satisfaction and happiness than those with unrestricted gift cards. Furthermore, because of the fact that restricted gift cards can be used in the particular issuing retailers, the limitation in store usability of restricted gift cards would provide more effective justification toward the use of the gift cards and the purchase in the only allowed retailor stores. Based on this logic, we expected that some product types which requires the higher level of justification such as hedonic products would benefit from the use of restricted gift cards than unrestricted gift cards. Therefore, it is hypothesized that the effect of gift cards type on choice satisfaction and happiness will be moderated by the product type(hedonic vs utilitarian). Specifically, in hedonic product which requires higher justification, consumers with restricted gift cards will feel higher satisfaction and happiness than those with unrestricted gift cards. However, in utilitarian product which there is lower needs for justification, there will be no difference between two gift card types on choice satisfaction and happiness. To examine these hypothesis, we conducted 5 experiments. In study 1a, we asked participants to recall the experience when they received the gift cards and how they felt choice satisfaction and happiness after using the card to purchase what they wanted. We found that those with restricted gift cards felt higher satisfaction and happiness than those with unrestricted gift cards. In study 1b, participants were asked to imagine that they received a birthday gift(10,000won), either in unrestricted gift card or restricted gift card and they were about to use the gift card in Starbucks. Then, they were asked to choose the product they would be willing to buy with the gift card and how they are satisfied and happy from the choice. The result revealed that compared to participants with unrestricted gift cards, those with restricted gift cards showed higher satisfaction and happiness. This result supports our hypothesis that restricted gift cards will more positively influence to receivers` choice satisfaction and happiness than unrestricted gift cards. Study 2 and 3 were conducted to figure out the moderating effect of product types(hedonic vs. utilitarian). Participants were randomly assigned to a condition in 2(gift card type: restricted vs. unrestricted) x 2(product: hedonic vs. utilitarian) between design. The result showed that there was a significant interaction effect between gift card type and product type. Specifically, in hedonic product condition, those with restricted gift card showed higher satisfaction and happiness than those with unrestricted gift card. On the other hand, in utilitarian condition, there was no difference depending on the gift card type. This is consistent with our hypothesis that product type will moderate the effect of gift card types on choice satisfaction and happiness. Study 4 was conducted in order to verify the mediation effect of justifiability. The result shows that in hedonic product condition, justifiability mediates the relationship between gift cards and choice satisfaction and happiness. That is, restricted gift card increases the justifiability and its justification increases the happiness and satisfaction. In conclusion, the goal of this article is to examine how the gift card types influence the gift- receiver`s choice satisfaction and happiness. Although unrestricted gift card outwardly seems to provide more positive influence to the receiver, our result suggests that restricted gift cards lead them to higher choice satisfaction and happiness rather than unrestricted gift cards. Also, justifiability mediated the relationship between gift cards and choice satisfaction and happiness. Based on this result, we suggest that gift card issuing companies need to facilitate restricted gift cards, especially for the business whose main products are hedonic products requiring justification. Additionally, we discuss theoretical and practical implications of the findings.

      • Assessment of Heavy Metal Exposure Via the Intake of Oriental Medicines in Korea

        Kim, Hyun-Kyung,Yoon, Eun Kyung,Jang, Junghoon,Hwang, Myungsil,Kim, JaYoung,Ha, Ji-Hye,Jang, Dong Deuk,Yoo, Tae Moo,Park, Kui Lea Informa UK (TaylorFrancis) 2009 Journal of toxicology and environmental health. Pa Vol.72 No.21

        <P>Oriental medical herbs are mainly natural products that are generated by simple processes, and therefore there is the possibility of contamination with various pollutants, including heavy metals. Heavy metals produce adverse effects in humans, and the toxicities of lead (Pb) and cadmium (Cd) are well established. This study evaluated the effects of exposure to Pb and Cd via the intake of the frequent prescriptions of oriental medicines, and assessed the risk to the Korean population based on domestic data. The average daily exposures to Pb and Cd were estimated. This is the first study to evaluate exposure and risk of heavy metal intoxication through intake of oriental medicines in Korea. Despite the uncertainties and limits of the data, these results simulate realistic exposure levels.</P>

      • The association of lipoprotein lipase PvuII polymorphism and niacin intake in the prevalence of metabolic syndrome: a KMSRI-Seoul study.

        Shin, Eunjung,Park, Na-Young,Jang, Yangsoo,Oh, Hyunhee,Jeong, Jayoung,Lim, Yunsook,Lee, Myoungsook New Century Health Publishers 2012 GENES AND NUTRITION Vol.7 No.2

        <P>Lipoprotein lipase (LPL) polymorphism correlated with LPL activity is associated with plasma lipid and lipoprotein levels. We aimed to investigate the frequency of LPL PvuII polymorphism and effects of LPL PvuII polymorphism and niacin intake on the prevalence of metabolic syndrome (MetSyn) in Koreans. Lifestyle questionnaires, anthropometry, and dietary records were completed, and LPL PvuII polymorphism, LPL mass, and lipid profiles were determined in 548 Koreans (MetSyn: 278, Non-MetSyn: 270). The MetSyn group showed a significantly lower frequency of P1P1 (wild type) and a higher frequency of P1P2 (hetero type) than the non-MetSyn group. The P2P2 (mutant type) group significantly showed lower levels of HDLc and LPL mass and a higher level of TG than the P1P1 group. As niacin intake increased, LPL mass decreased in the P2P2?group (r (2)?=?0.07). In particular, the lowest niacin intake group (14.82?mg/day) increased more than 3 times with regard to a higher risk of MetSyn than the others in the P2P2 mutant groups. However, the MetSyn risk declined 74% at the optimal levels of niacin intake (14.83-17.80?mg/day) in the P2P2?group compared to those of the P1 allele group. The findings indicate that optimal levels of niacin intake effectively decreased Korean MetSyn prevalence in the P2P2 mutant group.</P>

      • Structure–Activity Relationships of Neplanocin A Analogues as <i>S</i>-Adenosylhomocysteine Hydrolase Inhibitors and Their Antiviral and Antitumor Activities

        Chandra, Girish,Moon, Yang Won,Lee, Yoonji,Jang, Ji Yong,Song, Jayoung,Nayak, Akshata,Oh, Kawon,Mulamoottil, Varughese A.,Sahu, Pramod K.,Kim, Gyudong,Chang, Tong-Shin,Noh, Minsoo,Lee, Sang Kook,Choi, American Chemical Society 2015 Journal of medicinal chemistry Vol.58 No.12

        <P>On the basis of the potent inhibitory activity of neplanocin A (1) against S-adenosylhomocysteine (AdoHcy) hydrolase, we analyzed the comprehensive structure-activity relationships by modifying the adenine and carbasugar moiety of 1 to find the pharmacophore in the active site of the enzyme. The introduction of 7-deazaadenine instead of adenine eliminated the inhibitory activity against the AdoHcy hydrolase, while 3-deazaadenine maintained the inhibitory activity of the enzyme, indicating that N-7 is essential for its role as a hydrogen bonding acceptor. The substitution of hydrogen at the 6'-position with fluorine increased the inhibitory activity Of the enzyme. The one-carbon homologation at the 5'-position generally decreased the inhibitory activity of the enzyme, indicating that steric repulsion exists. A molecular docking study also supported these experimental data. In this study, 6'-fluoroneplanocin A (2) was the most potent inhibitor of AdoHcy hydrolase (IC50 = 0.24 mu M). It showed a potent anti-VSV activity (EC50 = 0.43 mu M) and potent anticancer activity in all the human tumor cell lines tested.</P>

      • Accumulation of autophagosomes contributes to enhanced amyloidogenic APP processing under insulin-resistant conditions

        Son, Sung Min,Song, Hyundong,Byun, Jayoung,Park, Kyong Soo,Jang, Hak Chul,Park, Young Joo,Mook-Jung, Inhee Landes Bioscience 2012 AUTOPHAGY Vol.8 No.12

        <P>Alzheimer disease (AD) is sometimes referred to as type III diabetes because of the shared risk factors for the two disorders. Insulin resistance, one of the major components of type II diabetes mellitus (T2DM), is a known risk factor for AD. Insulin resistance increases amyloid-β peptide (Aβ) generation, but the exact mechanism underlying the linkage of insulin resistance to increased Aβ generation in the brain is unknown. In this study, we investigated the effect of insulin resistance on amyloid β (A4) precursor protein (APP) processing in mice fed a high-fat diet (HFD), and diabetic <I>db/db</I> mice. We found that insulin resistance promotes Aβ generation in the brain via altered insulin signal transduction, increased BACE1/β-secretase and γ-secretase activities, and accumulation of autophagosomes. Using an in vitro model of insulin resistance, we found that defects in insulin signal transduction affect autophagic flux by inhibiting the mechanistic target of rapamycin (MTOR) pathway. The insulin resistance-induced autophagosome accumulation resulted in alteration of APP processing through enrichment of secretase proteins in autophagosomes. We speculate that the insulin resistance that underlies the pathogenesis of T2DM might alter APP processing through autophagy activation, which might be involved in the pathogenesis of AD. Therefore, we propose that insulin resistance-induced autophagosome accumulation becomes a potential linker between AD and T2DM.</P>

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