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Effect of Level of Feeding on the Performance of Crossbred Cows during Pre- and Post-partum Periods
Singh, Jatinder,Singh, Balwant,Wadhwa, M.,Bakshi, M.P.S. Asian Australasian Association of Animal Productio 2003 Animal Bioscience Vol.16 No.12
The study was undertaken to see the effect of elevated feeding during pre-partum or pre- as well as post-partum period on the productive and reproductive performance of crossbred cows. The experiment lasted for 60 d pre-partum to 120 d post-partum. Eighteen dry pregnant crossbred cows divided into three equal groups were fed either as per NRC feeding standard (C) or 20% above NRC during 60 d pre-partum ($T_1$) or fed 20% above NRC during both 60 d pre-partum to 120 d post-partum ($T_2$) period. During prepartum period body weight gain was significantly ($p{\leq}0.05$) higher in $T_1$ and $T_2$ groups than that of control group. The animals fed at higher plane of nutrition ($T_1$ and $T_2$) took significantly lesser time for complete relaxation of pelvic muscles, act of calving and for expulsion of placenta than that of control group. Moreover, such cows delivered 2 to 3 kg heavier calves as compared to normal fed dams. During post-partum period, the average daily milk yield was significantly higher in $T_2$ group than that in $T_1$ and control groups. The peak yield was significantly higher in $T_2$ group, it took longer time to reach peak production but it was more persistent in this group as compared to $T_1$ and control groups. Average milk fat, solids-not-fat (SNF) and total solids were significantly higher in $T_1$ and $T_2$ groups as compared to control group. Body weight losses incurred during early lactation were not even compensated by end of 4th month of lactation in C and $T_1$ groups whereas the animals in $T_2$ group gained 2.0 kg. The 1st post-partum estrus and conception rate were better in high fed groups ($T_1$ and $T_2$) than that of control group. The returns over feed cost of milk production were higher in $T_2$ group followed by $T_1$ and control groups indicating the advantage of elevated feeding during pre- and post-partum periods.
Understanding Painful Hip in Young Adults: A Review Article
( Jatinder Singh Luthra ),( Salim Al-habsi ),( Suwailim Al-ghanami ),( Soubhik Ghosh ),( Khamis Al-muzahemi ) 대한고관절학회 2019 Hip and Pelvis Vol.31 No.3
A wide number of disorders, including pathologies outside the hip, can cause and refer pain to hip. However, determining the cause of a painful hip can be a major challenge to orthopedic surgeons. Failure to diagnose and appropriately investigate pathologies of the hip in adults may result in delayed management and prolonged patient morbidity. A systematic approach to investigating the etiology of hip pain in adults (e.g., history, careful clinical and radiographic examination), will help identify the majority of clinically important pathologies which can cause hip pain. Conservative treatment and selective use of injection therapies has proven quite successful for the treatment of most causes of hip pain.
Singh, Nem,Singh, Jatinder,Kim, Dongwook,Kim, Dong Hwan,Kim, Eun-Hee,Lah, Myoung Soo,Chi, Ki-Whan American Chemical Society 2018 Inorganic Chemistry Vol.57 No.7
<P>Three-dimensional molecular architectures self-assembled with tripodal and tetratopic donors are valuable because of their encapsulation properties. Here, we present Co(I)-Fe(II)-Pd(II) heterotrimetallic trifacial barrel <B>1</B>, which was self-assembled using a newly synthesized tetratopic donor [CpCo(CbR<SUB>4</SUB>)] [<B>L</B>; Cp = cyclopentadienyl, Cb = cyclobudiene, and R = 4-(4-pyridylphenyl)] and a 90° acceptor [<I>cis</I>-(dppf)Pd(OTf)<SUB>2</SUB>] (<B>A1</B>; dppf = (diphenylphosphino)ferrocene and OTf = CF<SUB>3</SUB>SO<SUB>3</SUB><SUP>-</SUP>). The heterotrimetallic barrel <B>1</B> exhibited selective 1:1 interaction with a <I>N</I>,<I>N</I>′-dimethyl-1,4,5,8-naphthalenetetracarboxylic diimide guest, as revealed by <SUP>1</SUP>H NMR analysis. The self-assembly of donor <B>L</B> with two other Ru(II)-based 180° acceptors [(<I>p</I>-cymene)<SUB>2</SUB>Ru<SUB>2</SUB>(OO∩OO)(OTf)<SUB>2</SUB>] [OO∩OO = 6,11-dioxido-5,12-naphthacenedione (<B>A2</B>) and oxalate (<B>A3</B>)] resulted in tetragonal-prismatic cages. Self-assembly using the longer acceptor <B>A2</B> provided rare isomers of a tetragonal-prismatic cage by varying the orientation of the cyclopentadienyl moiety out-out (<B>2<SUB>a</SUB></B>) or out-in (<B>2<SUB>b</SUB></B>) of the cavity, whereas self-assembly using the shorter acceptor <B>A3</B> selectively resulted in the tetragonal-prismatic cage <B>3</B>. The three-dimensional molecular architectures <B>1</B>-<B>3</B> were characterized by combined spectroscopic and elemental analyses. The structures of molecular barrel <B>1</B> and prismatic cage <B>3</B> were elucidated by single-crystal X-ray analysis.</P><P>A Co(I)−Fe(II)−Pd(II) heterotrimetallic barrel was self-assembled using a newly synthesized cobalt sandwich-based donor and a (diphenylphosphino)ferrocene-based 90° Pd(II) acceptor. Coordination-driven self-assembly of the same donor with a Ru(II)-based 180° acceptor resulted in two isomers of a tetragonal-prismatic cage by varying the orientation of the cyclopentadienyl moiety out−out and out−in of the cavity.</P> [FIG OMISSION]</BR>
Management of the Leaky Wound After Arthroplasty: A Review
Luthra Jatinder Singh,Habsi Salim AL 대한창상학회 2023 Journal of Wound Management and Research Vol.19 No.3
Total knee and hip arthroplasty are widely performed surgeries for end stage osteoarthritis with highly successful outcomes. However, prolonged postsurgical wound drainage leads to slower healing and predisposes to periprosthetic joint infection. Persistent wound discharge after joint arthroplasty affects patient satisfaction and outcome measures, can cause unexplained re-admissions, and increases the cost burden on the health system. Preventive measures are crucial and include preoperative nutritional assessment, achieving adequate hemostasis, minimizing dead spaces and watertight wound closure. Monitoring these patients with serial C-reactive protein levels is strongly recommended. Many management strategies have been described for such complications, including cessation of deep venous thrombosis prophylaxis, dressings and wound care, antimicrobial therapy, surgical washout and polyethylene insert replacement. However, these conditions are not addressed thoroughly in the literature and optimal management protocol for such complications is still lacking. This article aimed to review the best available literature to date and summarize the findings to help physicians treating these wounds develop objective guidelines in identifying and managing such conditions.
A Tuber Lectin from Arisaema jacquemontii Blume with Anti-insect and Anti-proliferative Properties
Kaur, Manpreet,Singh, Kuljinder,Rup, Pushpinder Jai,Kamboj, Sukhdev Singh,Saxena, Ajit Kumar,Sharma, Madhunika,Bhagat, Madhulika,Sood, Sarvesh Kumar,Singh, Jatinder Korean Society for Biochemistry and Molecular Biol 2006 Journal of biochemistry and molecular biology Vol.39 No.4
A tuber lectin from Arisaema jacquemontii Blume belonging to family Araceae was purified by employing a single step affinity chromatography using column of asialofetuin-linked amino activated silica beads and the bound lectin was eluted with 100 mM glycine-HCl buffer pH 2.5. The purified A. jacquemontii lectin (AJL) showed a single protein band with an apparent molecular mass of 13.4 kDa when submitted to SDS-polyacrylamide gel electrophoresis under reducing as well as non-reducing conditions. The native molecular mass of AJL determined by gel filtration on a Biogel P-200 column was 52 kDa and its carbohydrate content was estimated to be 3.40%. Thus AJL is a tetrameric glycoprotein. The purified lectin agglutinated erythrocytes from rabbit but not from human. Its activity was not inhibited by any of the mono- and disaccharides tested except N-acetyl-D-lactosamine having minimal inhibitory sugar concentration (MIC) 25 mM. Among the glycoproteins tested only asialofetuin was found to be inhibitory (MIC $125\;{\mu}g/mL$). A single band was obtained in native PAGE at pH 4.5 while PAGE at pH 8.3 showed two bands. Isoelectric focusing of AJL gave multiple bands in the pI range of 4.6-5.5. When incorporated in artificial diet AJL significantly affected the development of Bactrocera cucurbitae (Coquillett) larvae indicating the possibility of using this lectin in a biotechnological strategy for insect management of cucurbits. Larvae fed on artificial diet containing sub-lethal dose of AJL showed a significant decrease in acid phosphatase and alkaline phosphatase activity while esterase activity markedly increased as compared to larvae fed on diet without lectin. Out of various human cancer cell lines employed in sulphorhodamine B (SRB) assay, this lectin was found to have appreciable inhibitory effect on the in vitro proliferation of HCT-15, HOP-62, SW-620, HT-29, IMR-32, SKOV-3, Colo-205, PC-3, HEP-2 and A-549 cancer cell lines by 82, 77, 73, 70, 41, 41, 37, 29, 21 and 21% respectively.
A Tuber Lectin from Arisaema jacquemontii Blume with Anti-insect and Anti-proliferative Properties
( Manpreet Kaur ),( Kuljinder Singh ),( Pushpinder Jai Rup ),( Sukhdev Singh Kamboj ),( Ajit Kumar Saxena ),( Madhunika Sharma ),( Madhulika Bhagat ),( Sarvesh Kumar Sood ),( Jatinder Singh ) 생화학분자생물학회 2006 BMB Reports Vol.39 No.4
Dhuna, Vikram,Bains, Jagmohan Singh,Kamboj, Sukhdev Singh,Singh, Jatinder,Shanmugavel,Saxena, Ajit Kumar Korean Society for Biochemistry and Molecular Biol 2005 Journal of biochemistry and molecular biology Vol.38 No.5
A lectin with in-vitro anticancer activity against established human cancer cell lines has been purified by affinity chromatography on asialofetuin-linked amino activated silica beads from the tubers of Arisaema tortuosum, popularly known as Himalayan Cobra lily, a monocot plant from the family Araceae. The bound Arisaema tortuosum lectin (ATL) was eluted with glycine-HCl buffer, pH 2.5. ATL was effectively inhibited by asialofetuin, a complex desialylated serum glycoprotein as well as by N-acetyl-D-lactosamine, a disaccharide. It gave a single band corresponding to a subunit molecular weight of 13.5 kDa in SDS-PAGE, pH 8.8 both under reducing and non reducing conditions. When subjected to gel-filtration on Biogel P-200, it was found to have a molecular weight of 54 kDa, suggesting a homotetramer structure, in which individual polypeptides are not bound to each other with disulfide bonds. ATL is a glycoprotein with 0.9% carbohydrate content, stable up to $55^{\circ}C$ and at pH 2 to 10. The lectin had no requirement for divalent metal ions i.e. $Ca^{2+}$ and $Mn^{2+}$ for its activity. However, as reported for other monocot lectins, ATL gave multiple bands in isoelectric focusing and Native PAGE, pH 8.3. The lectin was found to inhibit in vitro proliferation of human cancer cell lines HT29, SiHa and OVCAR-5.
Jatinder Gill,Jagdev Singh 대한설비공학회 2017 International Journal Of Air-Conditioning and Refr Vol.25 No.2
This paper presents an experimental analysis of a vapor compression refrigeration system (VCRS) using the mixture of R134a and LPGwith mass fractions of 28:72 as an alternative to R134a. In this work, we compare the energy performance of both refrigerants, R134a/LPG (28:72) and R134a, in a monitored vapor compression refrigeration system under a wide range of experimental conditions. So, the System with R134a/LPG (28:72) was tested by varying the capillary tube length and refrigerant charge under experimental conditions. Performance comparisons of both the systems are made taking refrigerant R134a as baseline, and the results show that the compressor power consumption, compressor discharge temperature and pull down time obtained with R134a/LPG (28:72) of 118 g and capillary tube length of 5.1 m in vapor compression refrigeration system are about 4.4% 2.4% and 5.3%, respectively, lower than that obtained with R134a in the studied range. Also, when using R134a/LPG (28:72), the system shows values of refrigeration capacity and COP are about 10.6% and 15.2% respectively, higher than those obtained using R134a, In conclusion, the mixing refrigerant R134a/LPG proposed in this study seems to be an appropriate long-term candidate to replace R134a as a new generation refrigerant of VCRS, because of its well environmentally acceptable properties and its favorable refrigeration performances.