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RISS 인기검색어
- 검색키워드
- 저자 : I. Celik (검색결과 3 건)
- 무료
- 기관 내 무료
- 유료
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Microstructural Changes of Anterior Corona Radiata in Bipolar Depression
I. Fatih Karababa,Huseyin Bayazıt,Nihat Kılıçaslan,Mustafa Celik,Hasan Cece,Ekrem Karakas,Salih Selek 대한신경정신의학회 2015 PSYCHIATRY INVESTIGATION Vol.12 No.3
ObjectiveaaIn bipolar disorder, dysregulation of mood may result from white matter abnormalities that change fiber tract length and fiber density. There are few studies evaluating the white matter microstructural changes in bipolar I patients (BD) with depressive episodes. The present study aimed to evaluate anterior corona radiata in BD patients with depressive episode using Diffusion Tensor Imaging (DTI). MethodsaaTwenty-one patients with bipolar depression and 19 healthy controls were investigated and groups were matched for age and gender. Diffusion-weighted echoplanar brain images (DW-EPI) were obtained using a 1.5 T MRI scanner. Regions of interest (ROIs) were manually placed on directional maps based on principal anisotropy. Apparent diffusion coefficient (ADC) and fractional anisotropy (FA) values of white matter were measured in the anterior corona radiata (ACR) bilaterally by diffusion tensor imaging. ResultsaaThere was not a significant difference between groups of age and gender (p>0.05). Significantly lower FA was observed in bilateral ACR in bipolar patients with depression compared with healthy individuals. And there is significantly higher ADC values in the left frontal corona radiate in bipolar patients. ConclusionaaWhite matter abnormalities can be detected in patients with BD using DTI. The neuropathology of these abnormalities is unclear, but neuronal and axonal loss, myelin abnormalities and reduced white matter fiber density are likely to be relevant.
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Large eddy simulation of a square cylinder flow: Modelling of inflow turbulence
M. Tutar,I. Celik 한국풍공학회 2007 Wind and Structures, An International Journal (WAS Vol.10 No.6
The present study aims to generate turbulent inflow data to more accurately represent the turbulent flow around a square cylinder when the inflow turbulence level is significant. The modified random flow generation (RFG) technique in conjunction with a previously developed LES code is successfully adopted into a finite element based fluid flow solver to generate the required inflow turbulence boundary conditions for the three-dimensional (3-D) LES computations of transitional turbulent flow around a square cylinder at Reynolds number of 22,000. The near wall region is modelled without using wall approximate conditions and a wall damping coefficient is introduced into the calculation of sub-grid length scale in the boundary layer of the cylinder wall. The numerical results obtained from simulations are compared with each other and with the experimental data for different inflow turbulence boundary conditions in order to discuss the issues such as the synthetic inflow turbulence effects on the 3-D transitional flow behaviour in the near wake and the free shear layer, the basic mechanism by which stream turbulence interacts with the mean flow over the cylinder body and the prediction of integral flow parameters. The comparison among the LES results with and without inflow turbulence and the experimental data emphasizes that the turbulent inflow data generated by the present RFG technique for the LES computation can be a viable approach in accurately predicting the effects of inflow turbulence on the near wake turbulent flow characteristics around a bluff body.
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Large eddy simulation of a square cylinder flow: Modelling of inflow turbulence
Tutar, M.,Celik, I. Techno-Press 2007 Wind and Structures, An International Journal (WAS Vol.10 No.6
The present study aims to generate turbulent inflow data to more accurately represent the turbulent flow around a square cylinder when the inflow turbulence level is significant. The modified random flow generation (RFG) technique in conjunction with a previously developed LES code is successfully adopted into a finite element based fluid flow solver to generate the required inflow turbulence boundary conditions for the three-dimensional (3-D) LES computations of transitional turbulent flow around a square cylinder at Reynolds number of 22,000. The near wall region is modelled without using wall approximate conditions and a wall damping coefficient is introduced into the calculation of sub-grid length scale in the boundary layer of the cylinder wall. The numerical results obtained from simulations are compared with each other and with the experimental data for different inflow turbulence boundary conditions in order to discuss the issues such as the synthetic inflow turbulence effects on the 3-D transitional flow behaviour in the near wake and the free shear layer, the basic mechanism by which stream turbulence interacts with the mean flow over the cylinder body and the prediction of integral flow parameters. The comparison among the LES results with and without inflow turbulence and the experimental data emphasizes that the turbulent inflow data generated by the present RFG technique for the LES computation can be a viable approach in accurately predicting the effects of inflow turbulence on the near wake turbulent flow characteristics around a bluff body.
KCI
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