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Therapeutic Effect of Dioctahedral Smectite on Diarrhea Caused by E. coli and Salmonella in Calves
Hu Jang Lee1,3*, Chun-Nam Cha, Yeo-Eun Lee, Hyunju Choi, Joon-Seob Shin, Suk Kim 충북대학교 동물의학연구소 2012 Journal of Biomedical and Translational Research Vol.13 No.2
The objectives of the current study were to evaluate the therapeutic effect of dioctahedral smectite (smectite) against calf diarrhea caused by pathogenic E. coli and/or Salmonella typhimurium. In this study, 20 calves (aged 2~3 months) with diarrhea were used for evaluation of the efficacy of smectite on calf diarrhea with 20% smectite suspension in PBS. Calves received 10 ml smectite suspension three times per day after feeding, and fecal samples were collected at the gate of treatment and on the first, second, third, fourth, and fifth day after administration. On the fifth day after treatment with smectite suspension, the diarrhea index showed a significant decrease in the treated group, compared to the control group (P<0.001). The number of pathogenic E. coli in feces of the treated group was significantly decreased, compared to each control group from the second day after treatment (P<0.001), and that of Salmonella typhimurium was significantly decreased from the first day after treatment (P<0.05). According to the results of the current study, 20% smectite suspension had a therapeutic effect on diarrhea caused by E. coli and/or Salmonella in calves.
Cha, Chun Nam,Yu, Eun-Ah,Shin, Min Jung,Park, Eun Kee,Choi, Hyunju,Kim, Suk,Lee, Hu Jang The Korean Society of Food Hygiene and Safety 2013 한국식품위생안전성학회지 Vol.28 No.3
Antibiotic Detection Kit (Combination I), a lateral flow immunoassay (LFIA) developed for the detection of antibiotic residues in milk, was utilized for the analysis of antibiotic residues in the muscle tissue of olive flounder. After 60-min treatment by dipping in water dosed with ampicillin (200-g/ton water), the residue depletion of ampicillin was investigated in 25 cultured olive flounder (Paralichthys olivaceus). Muscles of fish were sampled on the 1st, 2nd, 3rd, 4th and 5th day after drug treatment. The concentration of ampicillin in the muscle was determined by LFIA. The absorbance ratio of the sample to the control blank (Bs/Bo) was employed as an index to determine the muscle residues in olive flounder. To investigate the recovery rate, standard solutions were added to muscle samples to give final concentrations in the muscle of 4 and 8 ng/ml. The recovery rates of all spiked samples were > 96% of the spiked value. Ampicillin was detected in the muscle of fish treated with the drug until the 2nd day of the withdrawal period. The present study showed that the LFIA can be easily adopted to predict ampicillin residues in tissue of farmed fishes.
Core–shell strain structure of zeolite microcrystals
Cha, Wonsuk,Jeong, Nak Cheon,Song, Sanghoon,Park, Hyun-jun,Thanh Pham, Tung Cao,Harder, Ross,Lim, Bobae,Xiong, Gang,Ahn, Docheon,McNulty, Ian,Kim, Jungho,Yoon, Kyung Byung,Robinson, Ian K.,Kim, Hyunju Nature Publishing Group 2013 Nature materials Vol.12 No.8
Zeolites are crystalline aluminosilicate minerals featuring a network of 0.3–1.5-nm-wide pores, used in industry as catalysts for hydrocarbon interconversion, ion exchangers, molecular sieves and adsorbents. For improved applications, it is highly useful to study the distribution of internal local strains because they sensitively affect the rates of adsorption and diffusion of guest molecules within zeolites. Here, we report the observation of an unusual triangular deformation field distribution in ZSM-5 zeolites by coherent X-ray diffraction imaging, showing the presence of a strain within the crystal arising from the heterogeneous core–shell structure, which is supported by finite element model calculation and confirmed by fluorescence measurement. The shell is composed of H-ZSM-5 with intrinsic negative thermal expansion whereas the core exhibits a different thermal expansion behaviour due to the presence of organic template residues, which usually remain when the starting materials are insufficiently calcined. Engineering such strain effects could have a major impact on the design of future catalysts.
Antibacterial Effects of Galla Rhois Extract against Streptococcus suis Infection in Mice
Cha, Chun-Nam,Yu, Eun-Ah,Park, Eun-Kee,Choi, Hyunju,Kim, Suk,Lee, Hu Jang The Korean Society of Food Hygiene and Safety 2013 한국식품위생안전성학회지 Vol.28 No.2
Streptococcus suis (S. suis) is a major swine pathogen and an emerging zoonotic agent and is an increasing public health problem across Asia. The present study was undertaken to estimate the antibacterial effect of GR extract and therapeutic effect of GR extract against S. suis infection in mice. At the concentration of GR extract 2.5 mg/ml, the antibacterial effect was not shown on S. suis. However, the antibacterial effect against S. suis was observed at the concentration of GR extract 5.0 mg/ml. Oral administration of GR extract at the dose of 10 mg/kg showed a therapeutic effect for S. suis infected BALB/c mice. The mortality of GR extract-treated mice at the concentration of 5, 10 and 20 mg/kg was 80%, 70%, and 50% at 12 days, respectively, while that of untreated mice was 100% at 8 days after a lethal dose of S. suis infection. The results of our study strongly indicate that GR extract has potential as an effective for S. suis infection in mice.
대안적 리더십이 대학도서관 사서의 조직유효성인식에 미치는 영향에 관한 연구 - 감성지능의 조절효과를 중심으로 -
차현주,Cha, Hyunju 한국도서관정보학회 2018 한국도서관정보학회지 Vol.49 No.3
본 연구의 목적은 기존 리더십의 대안적인 개념인 공유 리더십, 진정성 리더십, 셀프 리더십이 대학도서관 사서들의 조직유효성 인식에 미치는 영향을 규명하는 것이다. 그리고 이러한 리더십 유형 중 어떤 리더십이 조직유효성 인식에 더 큰 영향을 미치는지, 각 리더십과 조직유효성의 관계에서 감성지능의 조절효과가 있는가에 대해 검증해 보고자 하는 것이다. 전국의 대학도서관 중 10인 이상의 정규직 사서가 근무하는 55개 대학도서관 사서 275명을 대상으로 140부의 설문지를 회수하여 분석하였다. 독립변인인 대안적 리더십과 조직유효성과의 영향 관계에서는 부분적으로 유의미한 관계가 도출되었고, 각 리더십의 종속변인에 대한 영향 차이에서는 셀프 리더십이 직무만족에 가장 큰 영향을 미쳤으며, 감성지능의 조절효과에 관한 검증 결과 공유 리더십과 조직유효성과의 관계에서 부분적인 조절효과가 나타나는 것으로 분석되었다. 본 연구는 리더십과 조직유효성의 영역에 새로운 개념과 사실을 주장하고 있지는 않지만, 문헌정보학 분야에서 비교적 연구되지 않았던 대안적 리더십에 대한 새로운 개념들에 대해 이론적 관계를 도입하는 기여를 하고 있다고 볼 수 있다. The purpose of this study is to investigate the effect of shared leadership, authenticity leadership, and self - leadership on the recognition of organizational effectiveness of university librarians, which is an alternative concept of existing leadership. The purpose of this study is to examine whether leadership styles have more influence on recognition of organizational effectiveness, and whether there is a moderating effect of emotional intelligence on the relationship between leadership and organizational effectiveness. A total of 140 questionnaires were collected from 275 librarians of 55 university librarians working in the university libraries nationwide. The effect of alternative leadership, which is an independent variable, on organizational effectiveness was partially derived, and self - leadership had the greatest effect on job satisfaction, and control effect of emotional intelligence The results of this study are as follows. Although this study does not claim new concepts and facts in the field of leadership and organizational validity, it can be said that it contributes to introducing the theoretical relation to new concepts of alternative leadership which has not been relatively studied in the field of linguistic informatics.
대학도서관에서 대안적 리더십의 의미와 적용에 관한 고찰
차현주,Cha, Hyunju 한국비블리아학회 2017 한국비블리아학회지 Vol.28 No.1
지식시회에 있어서 대안적 리더십은 수평적, 정서적인 접근, 책임감을 통해 조직원들을 동기부여 하여 자발적 참여를 유도하게 한다. 대안적 리더십에 대한 이론적 연구와 대학도서관에서의 적용 가능성에 대한 이론적 논의는 거의 전무하다. 본 연구에서는 그 첫걸음으로 대안적 리더십들에 대한 이론적 고찰과 대학 도서관에서 지식경영 패러다임 변화, 관리자와 사서의 역할 변화와 대안적 리더십 적용에 대한 논의를 통해 대학도서관을 주도할 사서들의 리더십 강화를 위한 개발 방향을 제시하고자 한다. In the knowledge society, alternative leadership induces voluntary participation by motivating the members through horizontal, emotional approach and responsibility. There is little theoretical discussion about theoretical research on alternative leadership and its applicability in university libraries. In this study, we will discuss the theoretical review of alternative leadership, the change of knowledge management paradigm in university library, the role of manager and librarian, and alternative leadership application. Through this, I would like to suggest the development direction for strengthening the leadership of the librarians who will lead the university library.
Point process approach to modeling and analysis of general cascading failure models
Lee, Hyunju,Cha, Ji Hwan Cambridge University Press 2016 Journal of applied probability Vol.53 No.1
<B>Abstract</B><P> A cascading failure is a failure in a system of interconnected parts in which the failure of a part can trigger the failure of successive parts. Although an initial and introductory approach for probabilistic modeling and analysis of the cascading failures was suggested in the literature, any general framework and fundamental results have yet to be reported. In this paper, applying the point process approach, we suggest a general framework for modeling and analysis of the cascading failures. Furthermore, a new concept of 'information-based residual lifetime' will be defined and discussed. </P>