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Jeon, Jaeho,Kim, Yongdeok,Kim, Jongryoul,Kang, Heejea,Ji, Hyunjin,Son, Woosung The Korean Association Of Orthodontists 2013 대한치과교정학회지 Vol.43 No.1
The aim of this paper was to propose a new method of bimaxillary orthognathic surgery planning and model surgery based on the concept of 6 degrees of freedom (DOF). A 22-year-old man with Class III malocclusion was referred to our clinic with complaints of facial deformity and chewing difficulty. To correct a prognathic mandible, facial asymmetry, flat occlusal plane angle, labioversion of the maxillary central incisors, and concavity of the facial profile, bimaxillary orthognathic surgery was planned. After preoperative orthodontic treatment, surgical planning based on the concept of 6 DOF was performed on a surgical treatment objective drawing, and a Jeon's model surgery chart (JMSC) was prepared. Model surgery was performed with Jeon's orthognathic surgery simulator (JOSS) using the JMSC, and an interim wafer was fabricated. Le Fort I osteotomy, bilateral sagittal split ramus osteotomy, and malar augmentation were performed. The patient received lateral cephalometric and posteroanterior cephalometric analysis in postretention for 1 year. The follow-up results were determined to be satisfactory, and skeletal relapse did not occur after 1.5 years of surgery. When maxillary and mandibular models are considered as rigid bodies, and their state of motion is described in a quantitative manner based on 6 DOF, sharing of exact information on locational movement in 3-dimensional space is possible. The use of JMSC and JOSS will actualize accurate communication and performance of model surgery among clinicians based on objective measurements.
Jaeho Jeon,Yongdeok Kim,Jongryoul Kim,Heejea Kang,Hyunjin Ji,Woosung Son 대한치과교정학회 2013 대한치과교정학회지 Vol.43 No.1
The aim of this paper was to propose a new method of bimaxillary orthognathic surgery planning and model surgery based on the concept of 6 degrees of freedom (DOF). A 22-year-old man with Class III malocclusion was referred to our clinic with complaints of facial deformity and chewing difficulty. To correct a prognathic mandible, facial asymmetry, flat occlusal plane angle, labioversion of the maxillary central incisors, and concavity of the facial profile, bimaxillary orthognathic surgery was planned. After preoperative orthodontic treatment, surgical planning based on the concept of 6 DOF was performed on a surgical treatment objective drawing, and a Jeon’s model surgery chart (JMSC) was prepared. Model surgery was performed with Jeon’s orthognathic surgery simulator (JOSS) using the JMSC, and an interim wafer was fabricated. Le Fort I osteotomy, bilateral sagittal split ramus osteotomy, and malar augmentation were performed. The patient received lateral cephalometric and posteroanterior cephalometric analysis in postretention for 1 year. The follow-up results were determined to be satisfactory, and skeletal relapse did not occur after 1.5 years of surgery. When maxillary and mandibular models are considered as rigid bodies, and their state of motion is described in a quantitative manner based on 6 DOF, sharing of exact information on locational movement in 3-dimensional space is possible. The use of JMSC and JOSS will actualize accurate communication and performance of model surgery among clinicians based on objective measurements.
Jeon, Hyunjin,Lee, Euiyeon,Kim, Dahee,Lee, Minhyung,Ryu, Jeahee,Kang, Chungwon,Kim, Soyoun,Kwon, Youngeun American Chemical Society 2018 ANALYTICAL CHEMISTRY - Vol.90 No.16
<P>Live-cell-based biosensors have emerged as a useful tool for biotechnology and chemical biology. Genetically encoded sensor cells often use bimolecular fluorescence complementation or fluorescence resonance energy transfer to build a reporter unit that suffers from nonspecific signal activation at high concentrations. Here, we designed genetically encoded sensor cells that can report the presence of biologically active molecules via fluorescence-translocation based on split intein-mediated conditional protein trans-splicing (PTS) and conditional protein trans-cleavage (PTC) reactions. In this work, the target molecules or the external stimuli activated intein-mediated reactions, which resulted in activation of the fluorophore-conjugated signal peptide. This approach fully valued the bond-making and bond-breaking features of intein-mediated reactions in sensor construction and thus eliminated the interference of false-positive signals resulting from the mere binding of fragmented reporters. We could also avoid the necessity of designing split reporters to refold into active structures upon reconstitution. These live-cell-based sensors were able to detect biologically active signaling molecules, such as Ca<SUP>2+</SUP> and cortisol, as well as relevant biological stimuli, such as histamine-induced Ca<SUP>2+</SUP> stimuli and the glucocorticoid receptor agonist, dexamethasone. These live-cell-based sensing systems hold large potential for applications such as drug screening and toxicology studies, which require functional information about targets.</P> [FIG OMISSION]</BR>
조건부 자율주행에서 제어권 전환 수행도와 제어권 전환 요청 시기에 따른 운전자의 시각적 탐색 전략에 대한 연구
전현진(HyunJin Jeon),명노해(Rohae Myung) 대한인간공학회 2020 大韓人間工學會誌 Vol.39 No.3
Objective: The purpose of this study is to analyze visual search strategies depended on takeover performance and takeover request lead time (TORlt) in Level 3 autonomous driving and derive eye movements for safe takeover. Background: Driver distraction while driving is a major accident factor. If their eye movements are dispersed or fixed at one point, this hinders information acquisition and proper decision-making, which leads to fatal accidents. Especially in Level 3 autonomous driving, as the driver is not obliged to monitor the driving scene, to ensure safe and successful takeover, drivers need to collect meaningful information during TORlt. Hence the study of the driver"s eye movements and attention allocation in TORlt is essential. Method: Eye movement data were collected using a glasses-type eye tracker in an autonomous driving simulator experiment, and classified into high- and lowperformance groups. The static aspects (number of fixation, fixation duration) as well as dynamic aspects (visual entropy) of eye movement were statistically analyzed through two-way ANOVA. Results: Results showed significant differences in both aspects of takeover performance and TORlt. Significant differences were observed in the destination lane and the side mirror located in the destination lane by the takeover performance. Moreover, there were significant differences in the forward area, non-driving related task (NDRT) and a sum of fixation duration by TORlt. Regarding the dynamic aspects, the visual entropy values became significantly higher as TORlt increased and as the takeover was performed better. Conclusion: The study quantitatively revealed meaningful areas of interest and eye movements for successful takeovers. Application: The results can be applied in designing in-vehicle systems and in the further analysis of dynamic eye movements in takeover situations.