The effects of Mo doping on 0.3Li[Li_0.33Mn_0.67]O₂·0.7Li[Ni_0.5Co_0.2Mn_0.3]O₂ cathode material

Park, Jin-Hwan,Lim, Jinsub,Yoon, Jaegu,Park, Kyu-Sung,Gim, Jihyeon,Song, Jinju,Park, Hyosun,Im, Dongmin,Park, Minsik,Ahn, Docheon,Paik, Younkee,Kim, Jaekook The Royal Society of Chemistry 2012 Dalton Transactions Vol.41 No.10

<P>Mo doped Li excess transition metal oxides formulated as 0.3Li[Li<SUB>0.33</SUB>Mn<SUB>0.67</SUB>]O<SUB>2</SUB>·0.7Li[Ni<SUB>0.5-<I>x</I></SUB>Co<SUB>0.2</SUB>Mn<SUB>0.3-<I>x</I></SUB>Mo<SUB>2<I>x</I></SUB>]O<SUB>2</SUB> were synthesized using the co-precipitation process. The effects of the substitution of Ni and Mn with Mo were investigated for the density of the states, the structure, cycling stability, rate performance and thermal stability by tools such as first principle calculations, synchrotron X-ray diffraction, field-emission SEM, solid state <SUP>7</SUP>Li MAS nuclear magnetic resonance (NMR), X-ray photoelectron spectroscopy (XPS), elemental mapping by scanning TEM (STEM), inductively coupled plasma atomic emission spectrometry (ICP-AES) and a differential scanning calorimeter (DSC). It was confirmed that high valence Mo<SUP>6+</SUP> doping of the Li-excess manganese-nickel-cobalt layered oxide in the transition metal enhanced the structural stability and electrochemical performance. This increase was due to strong Mo–O hybridization inducing weak Ni–O hybridization, which may reduce O<SUB>2</SUB> evolution, and metallic behavior resulting in a diminishing cell resistance.</P> <P>Graphic Abstract</P><P>Mo doped Li excess transition metal oxides formulated as 0.3Li[Li<SUB>0.33</SUB>Mn<SUB>0.67</SUB>]O<SUB>2</SUB>·0.7Li[Ni<SUB>0.5-x</SUB>Co<SUB>0.2</SUB>Mn<SUB>0.3-x</SUB>Mo<SUB>2x</SUB>]O<SUB>2</SUB> were synthesized using the co-precipitation process. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c2dt11833e'> </P>

Revolutionizing Galaxy Image Restoration with the Restormer Deep Learning Algorithm

Hyosun Park,Yongsik Jo,Seok-Un Kang,Taehwan Kim,M. James Jee 한국천문학회 2023 天文學會報 Vol.48 No.2

Bioactive compounds and antioxidant activity in three types of Korean watery kimchi

Park Hyosun,Kim Suna,Kim Jaecheol,Lee KyeongJin,Moon BoKyung 한국응용생명화학회 2024 Applied Biological Chemistry (Appl Biol Chem) Vol.67 No.-

Watery kimchi is a traditional fermented food served with its soup. In this study, we collected 21 samples of yeolmu mul kimchi (YMK), dongchimi (DC), and nabak kimchi (NK), respectively, which are the most popular watery kimchi in Korea. A composite sample of each watery kimchi was prepared for estimation of their bioactive compounds and antioxidant activities. Of the three kimchi types, YMK had the highest total carotenoid content (63.78 ± 4.88 mg/100 g, of which lutein, capsanthin, and β-carotene were the main carotenoids), and DC had the lowest (3.50 ± 0.12 mg/100 g). YMK also had the highest contents of chlorophyll (250.1 ± 3.91 mg/100 g), ascorbic acid (447.16 ± 8.95 mg/100 g), and capsaicinoids (2.51 ± 0.09 mg/100 g) compared to DC and NK. The lactic acid content was highest in NK (582.72 ± 29.10 mg/100 g). Moreover, YMK showed significantly higher antioxidant activity (ABTS and DPPH) than DC and NK (p < 0.05). Chlorophyll and antioxidant activity showed a strong positive correlation (p < 0.01). The results of this study highlighted watery kimchi as a potentially valuable source of bioactive compounds, and the carotenoids and capsaicinoids were affected by the supporting ingredients used in watery kimchi. Furthermore, watery kimchi provides 4.11% of the recommended daily intake of vitamin A according to the 2020 Korean dietary reference intakes.

Application of Denoising and Super-Resolution GAN to Hubble Ultra Deep Field Galaxies

Hyosun Park,Seok-Un Kang,Taehwan Kim,M. James Jee 한국천문학회 2022 天文學會報 Vol.47 No.2

후숙 조절 유전자 Pectate lyase와 Phytoene Synthase 편집용 CRISPR-Cas9 sgRNA의 유전자 편집 효율 측정

박효선 ( Hyosun Park ),양소희 ( So Hee Yang ),김의연 ( Euyeon Kim ),구연종 ( Yeonjong Koo ) 한국환경농학회 2021 한국환경농학회지 Vol.40 No.3

BACKGROUND: Tomato genome editing using CRISPR-Cas9 is being actively conducted in recent days, and lots of plant researches have been aiming to develop high valued crops by editing target genes without inserting foreign genes. Many researchers have been involved in the manipulation of the crop ripening process because fruit ripening is an important fruit phenotype for increasing fruit shelf life, taste, and texture of crops. This paper intends to evaluate target sgRNA to edit the two ripening-related genes encoding pectate lyase (PL) and phytoene synthase (Psy) with the CRISPR-Cas9 system. METHODS AND RESULTS: The CRISPR-Cas9 expression vector was cloned to target the PL (Solyc03g111690), Psy1 (Solyc03g031860), and Psy2 (Solyc02g081330) genes, which are the ripening genes of tomatoes. Tomatoes injected with Agrobacterium containing the CRISPR-Cas9 expression vector were further cultured for 5 days and used to check gene editing efficiency. As a result of the target gene sequence analysis by the next generation sequencing method, gene editing efficiency was calculated, and the efficient target location was selected for the PL and Psy genes. CONCLUSION: Therefore, this study was aimed to establish target sgRNA data that could have higher efficiency of the CRISPR-Cas9 system to obtain the delayed ripening phenotype of tomato. The developed method and sgRNA information is expected to be utilized in the development of various crops to manage its ripening processes.

전처리 조건에 따른 여주(Momordica charantia L.) 초절임의 쓴맛 감소와 품질평가

박효순(HyoSun Park),문보경(BoKyung Moon),김선아(Suna Kim) 한국식품과학회 2016 한국식품과학회지 Vol.48 No.5

본 연구는 여주(Momordica charantia L.) 의 강한 쓴맛으로 인해 음식재료로서의 활용이 제한적인 어려움이 있는 점을 개선하기 위해 전처리 조건을 달리하여 여주초절임을 제조한 후 총폴리페놀, 총플라보노이드, L-아스코브산, 유리아미노산 등의 함량을 분석하고, 산화방지 활성과 알파글루코시데이스 억제 활성을 측정하고, 색도, 텍스처, 관능검사를 수행하여 여주초절임의 쓴맛 저감효과와 품질 평가를 수행하였다. 여주 초절임의 유효성분 변화 중 총폴리페놀과 총플라보노이드는 5%-1분군이 가장 높은 함량으로 나타났으며, L-아스코브산 함량은 대조군이 높아 전처리 시행 시 L-아스코브산 손실이 있었다. 대조군과 5%-3분군의 총 유리아미노산의 함량 분석은 대조군에 비해 5%-3분군이 증가하는 경향을 보였으며, 특히 아르지닌과 글루탐산은 다른 유리아미노산들에 비해 높은 증가를 나타냈다. 산화방지 활성과 알파글루코시데이스 억제 활성에서 ABTS 라디칼 소거능과 DPPH 라디칼 소거능, 알파글루코시데이스 억제활성 모두 5%-1분군이 가장 높은 결과를 얻었으며, 이는 소금물 침지 및 데치기의 복합 전처리가 초절임 제조 후 산화방지 활성과 알파글루코시데이스 억제 활성을 높이는 효과적인 방법으로 사료된다. 색도 측정 결과 L값(lightness)은 실험군이 대조군보다 명도가 낮아지는 경향을 보였으며, a값은 전처리를 시행할수록 또 데치는 시간이 길수록 a값이 높아져 여주의 녹색이 퇴색되는 것으로 나타났고, b값은 황색이 낮게 나타났다. 경도 측정 결과 침지를 시행한 소금물의 농도와 데치는 시간 모두 경도에 영향을 주는것으로 나타났다. 관능검사에서 5%-3분군의 선호도가 높게 나타났으며, 색상을 제외한 조직감, 쓴맛 강도, 쓴맛 선호도, 전체적인 기호도에서 대조군과 실험군에서는 유의성이 있었으나 실험군 간 유의성은 없었다. 이는 초절임제조 전 소금물의 농도(1%, 5%)와 상관없이 20분간 침지한 후 데치기를 시행한 전처리 과정이 대조군보다 쓴맛은 감소하고 선호도가 증가함을 의미한다. 관능검사와 색도와 텍스처 측정을 통해 소금물의 농도와 상관없이 20분 침지 후 데치기를 시행하는 것이 쓴맛 저감 효과가 있는 결과를 얻었다. 그러나 여주초절임의 총폴리페놀, 총플라보노이드, ABTS와 DPPH 라디칼 소거 활성, 알파글루코시데이스 억제 활성의 결과가 5%-1분이 가장 높은 결과로 나타났다. 따라서 모든 연구 결과를 종합해 볼 때 관능검사에서 쓴맛 저감 효과가 있고 여주초절임의 유효성분과 산화방지 활성, 알파글루코시데이스 억제 활성 결과가 높은 5%-1분 조건이 가장 적합한 것으로 사료된다. 본 연구에서는 지금까지 여주의 쓴맛으로 인해 음식재료로서의 사용에 한계가 있었으나 위와 같이 쓴맛을 낮추는 전처리 조리조건을 제시함으로써 음식재료로서의 활용성을 증대할 수 있을 것이며, 나아가 쓴맛의 감소뿐만 아니라 유효성분의 파괴가 적은 여주 초절임 제품의 개발 가능성을 제시함으로써 다양한 가공식품으로의 개발 역시 가능할 것으로 사료된다. This study was performed to investigate the reduction in bitter taste and quality characteristics by pretreatments (brining; 1, 5% and blanching; 1, 3 min) in pickled bitter melon, respectively. We prepared picked bitter melon samples at 1%-1 min, 1%-3 min, 5%-1 min, 5%-3 min. Total polyphenol and total flavonoid contents were found to be the highest in 5%-1 min at 14.23±0.40 mg CE/g (dry) and 4.46±0.10 mg RE/g (dry), respectively. L-ascorbic acid level was the highest in control samples. Arginine and glutamic acid were increased by brining and blanching. ABTS and DPPH radical scavenging activity were found to be the highest at 43.60±0.40 and 44.88±0.20% at 5%-1 min, respectively. α-glucosidase inhibitory activity was the highest at 5%-1 min. The a value was statistically different, whereas L and b values were similar among different pretreatments. Hardness in pretreated samples was decreased as compared to that in the control. Among sensory evaluations, ‘color’ did not indicate any statistical difference, while ‘texture’, ‘bitterness preference’ and ‘overall preference’ increased with pretreatments, and ‘bitter intensity’ decreased.

생여주의 산화방지, 알파글루코시데이스 저해 활성 및 여주초절임의 카란틴과 루테인 함량 변화

박효순(HyoSun Park),문보경(BoKyung Moon),김선아(Suna Kim) 한국식품과학회 2018 한국식품과학회지 Vol.50 No.4

본 연구에서는 여주의 산화방지 활성과 알파글루코시데이스 저해 활성을 측정하고 총폴리페놀, L-아스코브산, 카란틴, 루테인 등 유효성분의 함량을 분석하였으며 초절임조건에서 카란틴과 루테인의 함량 변화를 비교하였다. 본 실험에 사용된 여주는 카란틴 777.92±27.59 mg/100 g, 루테인 16.87±2.07 mg/100 g, L-아스코브산 94.78±0.61 mg/100 g, 총폴리페놀 22.07±0.74 mg CE/g으로 나타났다. 여주추출물의 알파글루코시데이스 저해 활성은 추출물의 농도에 따라 0.5 mg/mL에서 55.60±1.34%, 1 mg/mL에서 80.40± 0.87%로 측정되었다. ABTS 라디칼 제거 활성은 여주추출물 5 mg/mL에서 31.76±0.42%, 10 mg/mL 61.98±0.27%였고, DPPH 라디칼 제거 활성은 여주추출물 5 mg/mL에서 56.19±2.39%, 10 mg/mL에서 89.51±0.25%로 측정되었다. 여주초절임의 전처리조건별 카란틴과 루테인의 함량을 비교한 결과, 여주초절임의 카란틴 함량은 PBM11 205.47±29.91 mg/100 g, PBM13 281.66±4.45 mg/100 g, PBM51 292.01±18.20 mg/100 g, PBM53 375.63±9.03 mg/100 g로 대조군 74.32±9.57 mg/100 g과 비교하여 모두 높게 나타났고. 여주초절임의 루테인 함량은 PBM111.57±0.13 mg/100 g, PBM13 1.99±0.28 mg/100 g, PBM51 3.18±0.52 mg/100 g, PBM53 4.07±0.40 mg/100 g이며 대조군은 0.70±0.07 mg/100 g보다 모두 높았다. 이는 여주초절임을 제조할 때 소금물침지와 데치기 단계가 여주에 함유된 카란틴과 루테인과 같은 유용성분의 손실이나 파괴를 방지하는 효과가 있는 것으로 판단된다. 특히, 5%소금물 침지와 3분 데치기를 한 PBM53군이 여주초절임의 루테인과 카란틴을 보존하는데 가장 효과적인 것으로 나타났다. This study aimed to analyze charantin and lutein from fresh bitter melon (FBM) for their antioxidant and α-glucosidase inhibitory activities. We subsequently compared our results with charantin and lutein content of pickled bitter melon (PBM11, PBM13, PBM51, and PBM53), obtained by brining (1 and 5% salt) and blanching (1 and 3 min). Charantin, lutein, L-ascorbic acid, and total polyphenolic content in FBM were 777.92±27.59, 16.87±2.07, 94.78±0.61, and 22.07±0.74 mg catechin equivalents/g on dry basis, respectively. Antioxidant activity of 5 mg/L FBM extract was 31.76±0.42% in ABTS assay and 56.19±2.39% in DPPH assay; α-glucosidase inhibitory activity of 0.5 mg/L FBM extract was 55.60±1.34%. Charantin and lutein content of all PBM samples were higher than control without brining and blanching treatments, those in PBM53 being 375.63±9.03 and 4.07±0.40 mg/100 g, respectively. These showed that brining and blanching in pickling process were very effective in retaining charantin and lutein in bitter melon.

Decursin and Z-Ligustilide in Angelica tenuissima Root Extract Fermented by Aspergillus oryzae Display Anti-Pigment Activity in Melanoma Cells

( Yuna Park ),( Dayoung Kim ),( Inho Yang ),( Bomee Choi ),( Jin Woo Lee ),( Seung Namkoong ),( Hyun Jung Koo ),( Sung Ryul Lee ),( Myung Rye Park ),( Hyosun Lim ),( Youn Kyu Kim ),( Sang-jip Nam ),( 한국미생물생명공학회(구 한국산업미생물학회) 2018 Journal of microbiology and biotechnology Vol.28 No.7

The anti-melanogenic effects of the extract of Angelica tenuissima (AT) root and the extract of AT root fermented by Aspergillus oryzae (FAT) were investigated. These effects were determined by measuring the inhibitory activity of AT and FAT on melanin production in B16F10 melanocytes and with in vitro tyrosinase activity assays. The AT extract inhibited melanin production at concentrations above 250 μg/ml, and this inhibitory effect was significantly enhanced by the fermentation process with A. oryzae. HPLC analysis resulted in the isolation of two active compounds from both the AT and FAT extracts. Their chemical structures were identified as decursin and Z-ligustilide through comparison with previously reported NMR data. The decursin and Z-ligustilide contents were increased in the FAT extract and could be responsible for its enhanced inhibitory effects on melanin production and tyrosinase activity compared with that of the AT extract.

임상 간호사의 환자 및 보호자로부터의 폭력 경험 실태와 폭력 경험별 대처 방법

박점미(Park, Jummi),신나연(Shin, Nayeon),박효선(Park, Hyosun) 전남대학교 간호과학연구소 2020 Nursing and Health Issues(NHI) Vol.25 No.2

Purpose: This research was done to investigate the violence experience and violence coping method of clinical nurses in a general hospital, and to help nurses to work in safe working places. Methods: Data were collected from January to March in 2017 for 73 nurses working in wards, intensive care unit and emergency room at one general hospital. Descriptive statistics, X²-test with the SPSS 25.0 program were used for data analysis. Results: 77.2% of participants experienced verbal abuse from patients, 35.2% experienced physical threat from patients and 86.3% of participants experienced violence whom 86.2% experienced verbal abuse and 20.7% experienced physical violence from patients. Over 50.0% of participants had coping methods(direct response, seeking for help, no action) of violence experience. Most frequent violence coping methods were ‘try to calm down by conversation (63.0%)’ followed by ‘report verbally to supervisor (52.1%)’, ‘Call for help with colleagues (52.1%)’. Conclusion: It is needed the support of the institutional communication system to prevent violence as well as tailored to clinical workplace to the clinical nurses cope more against violence.

부서의 업무과정특성과 가족친화분위기가 듀얼아젠다에 미치는 영향

박보람(Boram Park),김효선(Hyosun Kim),구자숙(Jasook Koo),박찬희(Chanhi Park) 한국인사조직학회 2007 인사조직연구 Vol.15 No.2

  여성 인력의 사회 진출과 맞벌이 부부의 증가 등의 사회변화로 인해 조직구성원들의 일과 가족의 조화는 조직에게도 매우 중요한 과제가 되었다. 본 논문에서는 조직 구성원들이 ‘일과 가족의 조화’를 잘 이룰 수 있는 것과 ‘조직 효과성 향상’을 동시에 달성할 수 있음을 밝혀낸 듀얼아젠다(Dual Agenda)의 이론적 틀에 입각하여, 두 가지 변인에 동시에 영향을 미치는 부서의 업무과정의 특성과 부서의 가족친화분위기의 효과에 대해 연구하였다. 본 연구는 부서의 업무과정 특성을 알아보기 위하여 지방자치단체의 한 부서를 중심으로 현장관찰을 실시하였으며, 가설의 검증을 위해서는 지방자치단체 40개부서의 289명을 대상으로 설문지를 실시하여 공변량 구조분석을 사용해 분석하였다. 연구 결과, 부서의 방해적인 업무과 정특성은 부서의 가족친화분위기와 부(-)의 관계를 나타냈으며, 부서의 효과성(성과ㆍ몰입ㆍ만족)과도 부(-)의 관계가 유의하게 나타났다. 그러나 부서의 방해적인 업무과정 특성은 종업원의 직장-가정 간 갈등과 직접적으로는 유의미한 관계를 보이지 않았다. 또한, 부서의 가족친화적인 분위기의 경우 직장-가정 간 갈등에 유의미한 관계를 보이지 않았고, 부서의 효과성과는 오히려 부(-)의 관계를 갖는 것으로 나타났다. 다시 말해서, 부서의 분위기가 가족 친화적이지 않을수록 부서의 성과지각과 부서몰입, 그리고 부서만족이 높아지는 경향이 발견되었다. 부서의 방해적인 업무과정 특성은 직접적으로는 부서의 효과성을 떨어뜨리는 효과가 있으나 부서의 분위기가 가족 친화적이지 않은 것이 오히려 부서의 효과성을 높인다는 모순된 결과를 보이고 있다. 이러한 결과가 앞으로의 듀얼아젠다 연구에 주는 시사점을 제시하였다.   As female labor market grows and dual income families increase, work-family balance is becoming a very important issue for corporate organizations. Dual agenda perspective proposes that the concern for work-family balance can enhance workplace effectiveness as it exposes ineffective work practices and aims to correct them. From this dual agenda perspective, we examined the effects that work process routines and family friendly atmosphere within a department have on an employees’ perception of work-family conflict and on departmental effectiveness. To measure the departmental effectiveness, we used three sub-constructs of team effectiveness: perceived performance of the department, departmental commitment, and satisfaction about the department.<BR>  Our hypotheses are as follows. Negative work process routines would increase the work-family conflict felt by employees (Hypothesis 1) and lower the departmental effectiveness (Hypothesis 2). Family-friendly atmosphere in the department will decrease employee’s work-family conflict (Hypothesis 3), while heighten the departmental effectiveness (Hypothesis 4). We also suggested that these relationships may differ by gender and the level of career aspiration.<BR>  In order to understand the link between work-family conflict and organizational effectiveness, we conducted participant observation at a PR department in a local government organization for 6 weeks from October to November, 2005. Through time logs, shadowing and interviews, we identified the characteristics of work process routine that has implication for both employee’s work-family conflict and departmental effectiveness. At the end of our participant observation, we delivered the questionnaire with four major constructs of our study (work process routine, family-friendly atmosphere, work-family conflict, and departmental effectiveness) to every employee of the organization. Among the 700 employees who received the questionnaire, 297 returned it, showing 42% of response rate. The final sample is composed of 289 respondents. The demographic characteristics of this sample are as follows: 65% were male employees, 81% were married, 53% belong to dual income family, 48% belonged to the 7th rank within the organization, and 74% is in the age group of between 30 and 50.<BR>  Data were analyzed with the structural equation modeling using AMOS 4.0. In our model, we set the work process routine and family-friendly atmosphere as exogenous variables and work-family conflict and departmental effectiveness as endogenous variables. Since there was a correlation of .49 between work process routine and family friendly atmosphere, we incorporated the correlation between the two exogenous variables into our model.<BR>  Our results show that positive work process routines did not have significant effect on reducing employees’ work-family conflict, rejecting Hypothesis 1. However, positive work process routines did increase all three dimensions of the perceived effectiveness of the department, supporting Hypothesis 2. In other words, employees working in the department with positive routines seem to perceive their departmental performance to be relatively high. They are also more committed to and satisfied with their department. As for the family-friendly atmosphere, it neither reduced the work family conflicts of employees nor increased the departmental effectiveness, rejecting both Hypothesis 3 and 4. On the contrary, we found that family-friendly atmosphere actually lowered the perceived departmental effectiveness. We also examined whether gender and employee’s career aspiration moderate the relationship among four major constructs. The result showed that neither gender nor individual career aspiration showed any significant moderating effect. To summarize, our findings showed that department characteristics, such as work process routines and family friendly atmosphere, had li