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Park, Hyeonji,Yoo, Siuk Springer-Verlag 2016 Genes & Genomics Vol.38 No.1
<P>Twine is a homolog of CDC25 phosphatase regulating cell cycle progression. To elucidate a possible role of twine during embryonic neurogenesis, its expression levels and patterns were determined. twine was strongly expressed in the embryonic brain, and segmentally expressed along the ventral nerve cord during stage 12-14 in which neuroblasts and ganglionic mother cells are rapidly dividing. To examine whether twine is involved in the nervous system development, immunohistochemistry using neuron-specific antibodies was performed. The results showed the reduction of dorsal clusters in the peripheral nervous system and disorganization of neurons in the central nervous system. Moreover, consistent with our microarray data, real-time PCR results show that expression level of twine is proportional to that of vnd, suggesting that Vnd functions as an activator to regulate twine expression. This relationship is also confirmed by analyzing the expression patterns of twine in vnd loss-of-function and gain-of-function mutant background. Immunostaining using anti-phospho-histone H3 and anti-BrdU antibodies revealed that Twine regulates cell cycle progression in the developing embryonic nervous system. Down-regulation of vnd also caused a significant reduction of mitotic cells in embryonic neuroblasts, suggesting a role for vnd-twine in mitosis-associated nervous system development.</P>
셀룰로오스 나노피브릴이 폴리비닐알코올을 이용한 함침 공정에 미치는 영향 기초 연구
박현지(Hyeonji Park),이제곤(Jegon Lee),박희태(Heetae Park),이석호(Seokho Lee),윤혜정(Hye Jung Youn) 한국펄프·종이공학회 2017 펄프.종이기술 Vol.49 No.4
Cellulose nanofibrils (CNF) is a promising reinforcement additive to make biocomposite due to their characteristics such as high aspect ratio, low density, high mechanical strength and high surface area. Polyvinyl alcohol (PVA), which is water-soluble and hydrophilic polymer, is usually applied to paper through surface sizing or impregnation. In this study, the possibility of CNF as a reinforcing additive to PVA solution was investigated in order to make stronger paper or improve the performance of paper through impregnation. The stability and rheology of the PVA/CNF suspension were measured and the mechanical properties of the impregnated paper were evaluated. In addition, the feature of surface of the impregnated paper was obtained. The CNF was miscible to PVA, and the mixed PVA/CNF suspension was stable. The impregnated paper with the suspension contained the CNF showed similar mechanical strength to the paper with only PVA, even at lower pickup weight.
수계에서 반응 가능한 실란화를 통한 셀룰로오스 나노피브릴의 소수화
박현지(Hyeonji Park),육심엽(Simyub Yook),박신영(Shin Young Park),윤혜정(Hye Jung Youn) 한국펄프·종이공학회 2018 펄프.종이기술 Vol.50 No.3
Cellulose nanofibrils (CNF) is a renewable material, which has a high aspect ratio, large specific surface area and high mechanical strength. However, since the hydrophilicity of CNF limits the expansion of the application, CNF is required to be hydrophobized in some cases. In this study, silylation of CNF under an aqueous system was investigated in order to increase the hydrophobicity of CNF. Methyltrimethoxysilane (MTMS) was selected as a silylating agent. The hydrophobicity of CNF was greater under acidic conditions and at a 1:1 oven-dried weight ratio of CNF and MTMS. The excessive amount of MTMS did not enhance the hydrophobicity of CNF. Curing treatment should be followed by the silylation of CNF. The hydrophobization of CNF could be carried out successfully under an aqueous system without an organic solvent.