大學生集團의 連讀開發을 위한 臨床硏究

金成烈,박화엽 西原大學校 1981 西原大學 論文集 Vol.10 No.-

The purpose of this study was to test the effects of speed reading development program which was constructed as the clinical treatments of the five psycho-phypical variables of eye movements and perceptual processes. The clinical treatments of this program were integrated with a reading activity to form a wholeness of behaviors and to synthesize the interaction effects among treatments. The output behaviors could be developed and explained, not in terms of fixation, comprehension, and saccading, but in terms of power, flexbility, speed, rhythm, focussing, concentation, and comprehension. Along with the four weeks' manipulation of an experimental time series design, both speed and comprehension variables of college students' reading behaviors were significantly developed at the level of reading their textbooks at the rate of about two thousand and six hundred words per minute which were easily contacted.

集中力訓練이 數學敎科 學習力에 미치는 影響

金永國,朴화燁,權五韓,李善娥 서원대학교 교육연구소 1999 敎育發展 Vol.18 No.2

This study was to analyze the effects of the training of mental concentration on the learning of mathematics. The assumption was to support that the higher the level of mental concentration the higher the achievements of mathematics. For the verification of the assumption were the following five questions listed. First, how can the trained variable of mental concentration be transformable into visual abilities for reading? Second, how can the trained variable of mental concentration be transformable into reading speed? Third, how can the trained variable of mental concentration be transformable into reading comprehension? Third, how can the trained variable of mental concentration be transformable into reading comprehension? Fourth, how can the trained variable of mental concentration be transformable into the higher level of mathematics learning? Fifth, how can the trained variable of mental concentration be transformable into the higher level of school achievements? Two matched groups of junior high school students were sampled for the experiment: One was experimental group for learning mental concentration program, and the other was controlled one. It took eighty-eight days to finish experiment. To the above questions were the answeres listed as the follows: For the independent variables manipulated was it showed that the posttest scores of visual performances focussed on reading were significantly higher than the pretest ones, that the posttest scores of reading speed variable were significantly higher than the pretest ones, and that in verifying the performance of experimental group the posttest scores of reading comprehension variable were not significantly higher than the pretest ones in controlled group. For the dependent variables was is showed that there were no significant differences of mathematics performances between the experimental and control group. And that there were no significant differences of academic performances between the experimental and control group. However, the three consecutive test scores of mathematics of experimental group were higher than the controlled one from the first sessions with treatment of mental concetration through the second to the third one without no treatment. It was concluded that there could exist the differences of learning and development rate in students' traits preformed in acedemic achievements when students were taught to learn mental concentration program designed for extra-curriculum.

讀書行動測定과 評價方法探究

박화엽,金善惠 서원대학교 교육대학원 2002 교육논총 Vol.6 No.-

This study was to construct two kinds of statistical knowledge: (1) Conceptual and numerical forms of representing reading behaviors, (2) validity and reliability in measuring reading behaviors and in evaluating reading education. The scales of those types of knowledge and information would have us elaborate reading knowledge and eliminate from jeopardizing the developments of reading processes negative behaviors: (1) Fixed dependency on ill-defined behaviors, (2) syndrome behaviors from the addicted, (3) poor knowledge and attitude of reading, (4) ignorance of professional knowledge and technology in reading education, (5) maladjustment of reading readiness, and (6) devaluation of reading. How can we be free from those pitfalls? The two kinds of solutions were as follows: First, it was known that arithmetic means would help us understand central tendency of distribution, geometric means would let us perceive the interactive effect of the two variables, and harmonic means could keep us calculating two times of fixed amount of reading and figuring out a mean value from two numeric variables. Second, it was shown that percentile knowledge could have us know the rank of reading ability for guiding comparative evaluation, and portfolio sheets should make us understand total dimensions of reading education which would be composed of four kinds of teaching and learning information and knowledge that should include teacher's intention and instructional processes, pupil's responses learned, parent's need and social demand for school education.

슬개골 골절에서 관절경을 이용한 정복 및 내 고정술

고상훈,조성도,나화엽,김우석,정유영,곽창렬,김범수 대한골절학회 2003 대한골절학회지 Vol.16 No.4

[PE-0050] Variation of w-6/w-3 Ratio by the combinations of Three mutant alleles of FAD2-1A with a hd gene in Soybean

Hwa Yeop Kim(Hwa Yeop Kim),Hyun Jo(Hyun Jo),Chang Wan Woo(Chang Wan Woo),Jong Tae Song(Jong Tae Song),Jeong-Dong Lee(Jeong-Dong Lee) 한국육종학회 2022 한국육종학회 공동학술발표집 Vol.2022 No.-

The veA gene is necessary for the negative regulation of the veA expression in Aspergillus nidulans

Kim, Hyoun-Young,Han, Kap-Hoon,Lee, Mimi,Oh, Miae,Kim, Hee-Seo,Zhixiong, Xie,Han, Dong-Min,Jahng, Kwang-Yeop,Kim, Jong Hwa,Chae, Keon-Sang Springer-Verlag 2009 Current genetics Vol.55 No.4

Isolation and proteomic characterization of bacterial extracellular membrane vesicles.

Kim, Gun-Hwa,Choi, Chi W,Park, Edmond C,Lee, Sang-Yeop,Kim, Seung Ii BENTHAM SCIENCE PUBLISHERS 2014 CURRENT PROTEIN AND PEPTIDE SCIENCE Vol.15 No.7

<P>The secretion of extracellular membrane vesicles (EMVs) is a common phenomenon that occurs in archaea, bacteria, and mammalian cells. EMVs contain biologically active proteins, which have diverse roles in biological processes. The outer membrane vesicles (OMVs) of Gram-negative bacteria and membrane vesicles (MVs) of Gram-positive bacteria have been discovered in various species. The main issues related to bacterial EMVs are their virulence, biogenesis mechanisms, host cell interaction mechanisms, and their potential use as new vaccine candidates. Recently, proteomics has become an essential tool for the characterization of EMVs. Proteomics is useful for the identification, quantification, and protein-protein interaction analysis of EMV protein components. This review describes the current understanding of secretory EMVs based on proteomic methods and the characteristics of various bacterial secretory EMVs. Finally, evidence for their potential roles and future applications are discussed.</P>

인간 연골세포에서 Heat Shock Protein 27의 발현이 세포사멸[apoptosis]에 미치는 영향

나화엽(Hwa-Yeop Na),김영태(Yung-Tae Kim),장재석(Jae-Suk Chang),박종훈(Jong-Hoon Park),김정화(Jung-Hwa Kim),윤경동(Kyung-Dong Yoon),정유영(You-Young Jung),김우석(Woo-Suk Kim) 대한정형외과학회 2002 대한정형외과학회지 Vol.37 No.1

Dially disulfide prevents 1,3-dichloro-2-propanol-induced hepatotoxicity through mitogen-activated protein kinases signaling

Chang-Yeop Kim,Jin-Hwa Kim,Da-Young Jung,Tae-Won Kim,Je-Won Ko 한국실험동물학회 2021 한국실험동물학회 학술발표대회 논문집 Vol.2021 No.7

Dially disulfide (DADS) is organosulfur component of Galic (Allium sativum) which has traditionally been used as a medicinal food and exhibits various beneficial activities, such as antitumor, antimicrobial, hypolipidemic, antiarthritic, and hypoglycemic activities. Hence, in this study we investigated the protective effects of DADS against 1,3-dichloro-2-propanol (1,3-DCP)-induced acute hepatotoxicity in rats. DADS was gavaged to rats once daily for 7 days at doses of 30 and 60 mg/kg/day. One hour after the final DADS treatment, the rats were administrated 90 mg/kg of 1,3-DCP to induce acute hepatotoxicity. 1,3-DCP induced significantly in the serum aminotransferase levels and alanine aminotransferase level in serum. However, DADS-treated animals significantly suppressed the increased serum aminotransferases levels, which is accompanied with the reduction in histopathological alterations in liver. DADS-treated animals showed the significant reduction in malondialdehyde production compared with the 1,3-DCP-administrated animals. Furthermore, DADS-treated animal markedly increased the anti-oxidative enzymes activities including catalase, glutathione S-transferase, and glutathione reductase compared to 1,3-DCP-administrated animals. 1,3-DCP administration exhibited the apoptosis in liver with increases in phosphorylation of mitogen-activated protein kinases (MAPKs), especially extracellular signal-regulated kinase and p38 MAPK. Whereas DADS treatment showed the marked reduction in these alterations. In addition, DADS pretreatment suppressed cytochrome P450 2E1 (CYP2E1) expression. These results suggest that the protective effects of DADS against 1,3-DCP-induced hepatotoxicity possibly involve mechanisms related to ability to induce antioxidant enzymes, block metabolic activation of 1,3-DCP by suppressing CYP2E1, and anti-apoptotic properties by inhibiting phosphorylation of MAPKs.

CIE suppresses inflammatory responses induced by ovalbumin-induced allergic asthma model in mice

Jin-Hwa Kim,Chang-Yeop Kim,Da-Young Jung,Je-Won Ko,Tae-Won Kim 한국실험동물학회 2021 한국실험동물학회 학술발표대회 논문집 Vol.2021 No.7

The inner shell of the chestnut (Castanea crenata) known to contain various polyphenol, which exert beneficial biological effect. Hence, we evaluated the anti-inflammatory effects of the chestnut inner shell extract (CIE) in an ovalbumin (OVA)-induced mouse model. We injected 20 ug of OVA with 2 mg of aluminum on day 0 and day 14 to induce allergic airway inflammation in six-week-old BALB/c mice, and mice were challenged with 1% OVA by nebulization for 1 h on days 21, 22, and 23. CIE was orally administered at 50 mg/kg and 200 mg/kg from day 18 to 23, and its effects were compared with those of dexamethasone treatment. CIE significantly reduced proinflammatory cytokines, inflammatory cell counts, and immunoglobulin-E compared to those in the OVA-induced allergic airway inflammation model. Those of anti-inflammatory effects were evidenced by the decreases in inflammatory cell recruitment and mucus production in lung tissue. Furthermore, CIE reduced the OVA-induced nuclear factor kappa B (NF-κB) phosphorylation, and accordingly the expression of inducible nitric oxide synthase (iNOS), cyclooxygenase) COX-2 and matrix metalloproteinase-9 (MMP-9) were decreased sequentially in lung tissues. In conclusion, CIE showed the protective effects on OVA-induced allergic airway inflammation via the suppression of NF-κB phosphorylation and the sequentially reduced expression of iNOS, COX-2 leading to reduced MMP-9 expression. These results indicate that CIE is a potential therapeutic agent for allergic airway inflammation.