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- 저자 : Hongxia Peng (검색결과 4 건)
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Jilin Hu,Qizhong Huang,Hongxia Peng,Xiuying Tian,Zhanjun Chen,Yangxi Peng 한양대학교 세라믹연구소 2018 Journal of Ceramic Processing Research Vol.19 No.3
Aluminium oxide (Al2O3)-aluminium nitride (AlN) composites were prepared at 1500-1600 oC by pressureless sintering. Themain raw materials used were AlN and Al2O3, and appropriate amounts of TiO2-Y2O3-CaO-La2O3 quaternary sintering aidswere added. The effects of different AlN contents and sintering temperatures on the bulk density, bending strength, Rockwellhardness, thermal conductivity, and other properties of Al2O3-based ceramics were studied. The phase composition andmicrostructure of the samples were analysed with an X-ray diffractometer and scanning electron microscope. Results showedthat the Al2O3-AlN composites had excellent overall performance in terms of a flexural strength of 295.7MPa, a Rockwellhardness of 61.5 HRA, and a thermal conductivity of 38.8W/(m·K) (at 25 oC) after pressureless sintering at 1600 oC for 3 hwith 10 wt% AlN content. These properties met the requirements of high-power ceramic LED lamp holders. The Al2O3-10 wt%AlN composites sintered at 1600 oC had a dense microstructure, tight bonding among grains, and few pores, whichexplained the excellent performance of the samples.
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Liu Lu,Wang Manjiang,Gong Ning,Tian Peng,Deng Hongxia 한국통합생물학회 2021 Animal cells and systems Vol.25 No.5
Selenium (Se) is a vital element of life, which has an important impact on the growth, development, production performance and stress-tolerance of animals. However, it is not entirely clear that how exactly Se works during these processes. Herein, we investigate the role of Se in regulating the functions of goat mammary epithelial cells (GMECs) under heat-stress condition. We found that heat stress caused ferroptosis-like death in GMECs, manifested by a robust increase in iron ion concentration, reactive oxygen species (ROS) and cell death ratio, and a decrease in the activity of superoxide dismutase (SOD) and expression level of glutathione peroxidases 4 (GPX4). Se incubation had no obvious effect on GMEC viability, but alleviated heat-stress-induced ferroptosis-like cell death and improved GPX4 expression and SOD activity in a dose-dependent manner. Also, we found that overexpression of GPX4 could improve the activity of SOD. And Se incubation inhibited activation of mTOR signaling in heat-stress-induced GMECs, which could be eliminated by the mTOR activator MHY1485, and treatment with mTOR inhibitor AY-22989 had the same effect as Se. In conclusion, Se improves GPX4 expression and SOD activity and inhibits the activation of mTOR to alleviate heatstress- induced ferroptosis-like death in GMECs, whichmay be a protective agent for heat stress in goats.
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Jilin Hu,Xiuying Tian,Chuanyue Hu,Yige Luo,Hongxia Peng,Jinqiu Luo 한양대학교 세라믹연구소 2016 Journal of Ceramic Processing Research Vol.17 No.11
Different types of aluminum sources (such as Al2O3 and Al(OH)3) were used to prepare an Al2O3-ZrO2 composite powder inan alcohol-water system, in which ZrOCl2·8H2O and NH4HCO3 were used as starting material and precipitant, respectively. This study explores the effects of different types of aluminum sources and heat treatment on the preparation of Al2O3-ZrO2composite powder. The sintering property of the Al2O3-ZrO2 composite powder prepared from different types of aluminumsources was also investigated. Results indicate that Al2O3-ZrO2 composite powder prepared from Al(OH)3-containingprecursors after calcination at 600 oC possesses a relatively uniform spherical structure, with particle size ranging from 50 nmto 100 nm. As the calcination temperature increases, the particle size of powder prepared using precursors that containAl(OH)3 increases and the micro appearance of the particles gradually shifts from a mainly spherical structure to a diversifiedstructure, which can be spherical, sheet-like or rod-like. The Al2O3-ZrO2 composite powder prepared from Al(OH)3-containingprecursors exhibits satisfactory sintering property. The relative density of the sintered sample reaches 98.5%, and the Rockwellhardness reaches 85.5 HRA after sintering of the composite powder at 1550 oC for 2 hrs
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Current status, challenges, and future prospects of plant genome editing in China
Sulaiman Ahmed,Yandi Zhang,Muhammad Abdullah,Qiuxiang Ma,Hongxia Wang,Peng Zhang 한국식물생명공학회 2019 Plant biotechnology reports Vol.13 No.5
Genome editing (GE) is the most powerful tool for creating genetic variation in plants. This approach is valuable for studying the mechanism of gene function and regulation as well as to improve desirable traits using sequence-specific endonucleases. It is typically performed with diverse molecular scissors that cleave a particular gene at a defined position. The advent of sequence-specific nucleases such as ZFNs (zinc finger nucleases), TALENs (transcription activator-like effector nucleases), and CRISPR (clustered regularly interspaced short palindromic repeats), in particular, have allowed for the precise and efficient introduction of genetic variation into the genome. The newly developed CRISPR-associated protein 9 (Cas9) variants, base-editing systems, novel RNA-directed nucleases, and DNA-free CRISPR/Cas9 delivery methods offer great opportunities for plant genome engineering. China has made tremendous progress in the field of GE for crop improvement to meet the demand of growing population. Herein, we reviewed the recent progress in GE of different crops in China, highlighting advanced GE tools/methods, and also discussed the specific challenges and prospects of plant GE.
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