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Testicular Characteristics and the Block to Spermatogenesis in Mature Hinny
Han, Hongmei,Wang, Aihong,Liu, Liming,Zhao, Gaoping,Su, Jie,Wang, Biao,Li, Yunxia,Zhang, Jindun,Wu, Baojiang,Sun, Wei,Hu, Shuxiang,Li, Shuyu,Zhao, Lixia,Li, Xihe Asian Australasian Association of Animal Productio 2016 Animal Bioscience Vol.29 No.6
Most hinnies (female donkey${\times}$male horse) and mules (female horse${\times}$male donkey) are sterile with few reports of equine fertile hybrids. The main cause of this sterility is thought to be a meiotic block to spermatogenesis and oogenesis. This study compared the developmental features of the testes and a histological analyses of spermatogenesis in a male hinny with those of a normal, fertile stallion and Jack donkey. Hinny testes showed a thicker tunica albuginea, fewer blood vessels and more connective tissue in the testis parenchyma than those of the stallion and Jack donkey. Although the mean number of seminiferous tubules was significantly higher in stallion and hinny than Jack donkey (p<0.01), the mean proportion of seminiferous tubules was lower in the hinny (p<0.01) which resulted in a smaller diameter of seminiferous tubules. The mean number of spermatogonia and spermatocytes per unit area were significantly lower in hinny testis (p<0.01) and no spermatids or mature spermatozoa cells were found during immunofluorescent analyses. These results indicated that defects in seminiferous tubule development and structure occur in the testis of hinnies. Furthermore, most spermatogonia and spermatocytes cease development in synapsis during mid-meiosis of spermatocytes, which results in a block to spermatogenesis that prevents the formation of spermatids and matured spermatozoa during meiosis in male hinnies.
Optimized Design of Low Voltage High Current Ferrite Planar Inductor for 10 ㎒ On-chip Power Module
Seok Bae,Yang-Ki Hong,Jae-jin Lee,Gavin Abo,Jeevan Jalli,Andrew Lyle,Hongmei Han,Gregory W. Donohoe 한국자기학회 2008 Journal of Magnetics Vol.13 No.2
In this paper, design parameters of high Q (> 50), high current inductor for on-chip power module were optimized by 4 Xs 3 Ys DOE (Design of Experiment). Coil spacing, coil thickness, ferrite thickness, and permeability were assigned to Xs, and inductance (L) and Q factor at 10 ㎒, and resonance frequency (?r) were determined Ys. Effects of each X on the Ys were demonstrated and explained using known inductor theory. Multiple response optimizations were accomplished by three derived regression equations on the Ys. As a result, L of 125 nH, Q factor of 197.5, and ?r of 316.3 ㎒ were obtained with coil space of 127 ㎛, Cu thickness of 67.8 ㎛, ferrite thickness of 130.3 ㎛, and permeability 156.5. Loss tan δ = 0 was assumed for the estimation. Accordingly, Q factor of about 60 is expected at tan δ = 0.02.