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RISS 인기검색어
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- 저자 : Hock Gan Heng (검색결과 2 건)
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Canine biphasic synovial sarcoma:case report and immunohistochemical characterization
Panayiotis Loukopoulos,Hock Gan Heng,Habibah Arshad 대한수의학회 2004 Journal of Veterinary Science Vol.5 No.2
The clinical, radiological and pathologic features of a biphasic synovial sarcoma in the left elbow joint of a twoyear- old male Rottweiler are presented. The tumor showed positive immunoreactivity for vimentin, Epithelial Membrane Antigen (EMA), p53 and PCNA, while it was negative for the cytokeratin used, S-100, Rb and p21. Immunohistochemistry for EMA allowed the identification of epithelioid components of synovial sarcoma, and may, therefore, contribute in establishing a diagnosis of biphasic synovial sarcoma. Intratumoral variation in PCNA immunoreactivity was minimal, indicating that the various tumor components proliferate at more or less similar rates. Overall, the characterized immunohistochemical profile for canine synovial sarcoma, not defined previously, may provide clues to the histogenesis of the phenotypically mesenchymal and epithelial elements of the tumor, and may be of value in the differential diagnosis of challenging cases, decreasing the risk of under- and mis-diagnosis. Although more cases need to be studied to determine whether there is a consistent pattern of immunostaining in canine synovial sarcoma, its potential significance is discussed in relation to the histogenesis, molecular pathology and differential diagnosis of canine synovial sarcoma.
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Quantitative CT Evaluation for Lung Volume and Density in Dogs
최수영,이인,정우창,Hock Gan Heng,이영원,최호정 한국임상수의학회 2014 한국임상수의학회지 Vol.31 No.5
In this study, we analyzed the computed tomography (CT) measurements of lung volume and density indogs with relation to body weight, age, sex, and breed. The multi-detector CT examination of the thorax was performedon dogs without respiratory or cardiovascular diseases. Three-dimensional reconstruction of CT images facilitatedmeasurement of lung volume and density. There was a statistical significant correlation between body weight and lungvolume (p < 0.0001). Lung density significantly decreased with an increase in body weight (p = 0.0078). However,no correlation was seen between these lung parameters and either sex or age of the dogs. In conclusion, this studyshows that body weight is an important factor to consider when interpreting total lung volume and density valuesmeasured by quantitative CT. We highlight the need for further study using quantitative CT in identifying the potentialeffects of sex, age, and disease status on these parameters.
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