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      • KCI등재

        A Review on Assessment of Fatigue Strength in Welded Studs

        Jörg Hildebrand1,Hadi Soltanzadeh2 한국강구조학회 2014 International Journal of Steel Structures Vol.14 No.2

        Welding is one of the most important and highly developed joining methods; nevertheless unwanted side effects occur likethermal strains and altering of certain material properties induced by heating and melting. These effects lead to distortions andhigh residual stresses which should be kept to a minimum. To minimize distortion, various strategies are being developed. Studwelding is widely used in steel structures, power plants, and ship buildings due to the significantly technology including highestquality of production processes by continuous electrical control and the efficiency of such a process. Therefore, varying theheat input typically will affect the material properties including yield strength, tensile strength, hardness, and notch toughnessin the stud arc welding. Well-defined heat sources offer a reproduced heat input into a highly localized area. The fatigue strengthof stud welding has been investigated by performing welding process and microstructural observations. This paper is going todiscuss the influence of heat input on the structural changes in stud arc welding.

      • SCISCIESCOPUS

        Whole-brain serial-section electron microscopy in larval zebrafish

        Hildebrand, David Grant Colburn,Cicconet, Marcelo,Torres, Russel Miguel,Choi, Woohyuk,Quan, Tran Minh,Moon, Jungmin,Wetzel, Arthur Willis,Scott Champion, Andrew,Graham, Brett Jesse,Randlett, Owen,Plum Nature Publishing Group, a division of Macmillan P 2017 Nature Vol.545 No.7654

        <P>High-resolution serial-section electron microscopy (ssEM) makes it possible to investigate the dense meshwork of axons, dendrites, and synapses that form neuronal circuits(1). However, the imaging scale required to comprehensively reconstruct these structures is more than ten orders of magnitude smaller than the spatial extents occupied by networks of interconnected neurons(2), some of which span nearly the entire brain. Difficulties in generating and handling data for large volumes at nanoscale resolution have thus restricted vertebrate studies to fragments of circuits. These efforts were recently transformed by advances in computing, sample handling, and imaging techniques(1), but high-resolution examination of entire brains remains a challenge. Here, we present ssEM data for the complete brain of a larval zebrafish (Danio rerio) at 5.5 days post-fertilization. Our approach utilizes multiple rounds of targeted imaging at different scales to reduce acquisition time and data management requirements. The resulting dataset can be analysed to reconstruct neuronal processes, permitting us to survey all myelinated axons (the projectome). These reconstructions enable precise investigations of neuronal morphology, which reveal remarkable bilateral symmetry in myelinated reticulospinal and lateral line afferent axons. We further set the stage for whole-brain structure-function comparisons by co-registering functional reference atlases and in vivo two-photon fluorescence microscopy data from the same specimen. All obtained images and reconstructions are provided as an open-access resource.</P>

      • KCI등재후보

        Computer Aided Composition, Timbral Synthesis, & Electro-Acoustic SuperInstruments: An Exploration of Heaviness in Electro-Acoustic Chamber Music

        Nolan Hildebrand 한국전자음악협회 2022 에밀레 Vol.20 No.-

        In his article 'Reigen seliger Geister' (On My Second String Quartet) (2004), Helmut Lachenmann used the term super-instrument to describe moments in his work where the string quartet is treated homophonically as a single “16-stringed sonic mechanism” through “unison sound and unison rustling, i.e. the synchronous multiplication or amplification of sound or noise” (2004, p. 62) and/or the “parallel deployment of tones greatly separated in sonic space” (2004, pp. 64). In my Masters Thesis composition “Tripping in the Horror Vacui” for amplified violin, amplified cello, and amplified piano with electronics, Lachenmann’s idea of the super-instrument is extended with digital music technology and electro-acoustic tools such as computer aided composition, timbral synthesis, live processing, and multichannel spatialization. By utilizing computer aided composition, the composer/author derived pitch information from noisy samples of raw data sonfications used in the work’s fixed media/“tape track”. This pitch material derived from the raw data sonifications in the fixed media is then mapped to the performer’s instrumental writing to create homophonic textures. The material between the performers and the fixed media is then synthesized in the performance space with either a stereo or 7.1 multichannel speaker setup to create a huge and distorted electro-acoustic super-instrument. Creating these electro-acoustic super-instruments in my own works allows me to sculpt enormous melodic gestures that stretch out over the multichannel speaker setup thus also incorporating the “parallel deployment of tones greatly separated in sonic space” (2004, pp. 64). In Tripping in The Horror Vacui, these larger-than-life electro-acoustic superinstruments embody a maximalist aesthetic to create a heavy and sublime experience that overwhelms the audience through metal music tropes, density, intensity, and amplitude.

      • KCI등재
      • Generation of a human induced pluripotent stem cell line from urinary cells of a healthy donor using an integration free vector

        Rossbach, B.,Hildebrand, L.,El-Ahmad, L.,Stachelscheid, H.,Reinke, P.,Kurtz, A. Elsevier 2016 Stem cell research Vol.16 No.2

        <P>We have generated a human induced pluripotent stem cell (iPSC) line derived from urinary cells of a 30 year old healthy female donor. The cells were reprogrammed using a non-integrating viral vector and have shown full differentiation potential. Together with the iPSC-line, the donor provided blood cells for the study of immunological effects of the iPSC line and its derivatives in autologous and allogeneic settings. The line is available and registered in the human pluripotent stem cell registry as BCRTi004-A. (C) 2016 The Authors. Published by Elsevier B.V.</P>

      • Generation of a human induced pluripotent stem cell line from urinary cells of a healthy donor using integration free Sendai virus technology

        Rossbach, B.,Hildebrand, L.,El-Ahmad, L.,Stachelscheid, H.,Reinke, P.,Kurtz, A. Elsevier 2017 Stem cell research Vol.21 No.-

        <P>We have generated a human induced pluripotent stem cell (iPSC) line derived from urinary cells of a 28 year old healthy female donor. The cells were reprogrammed using a non-integrating viral vector and have shown full differentiation potential. Together with the iPSC line, the donor provided blood cells for the study of immunological effects of the iPSC line and its derivatives in autologous and allogeneic settings. The line is available and registered in the human pluripotent stem cell registry as BCRTi005-A. (C) 2016 The Authors. Published by Elsevier B.V.</P>

      • SCOPUSKCI등재

        Morphological variation of the velum in children and adults using magnetic resonance imaging

        Kotlarek, Katelyn J.,Haenssler, Abigail E.,Hildebrand, Kori E.,Perry, Jamie L. Korean Academy of Oral and Maxillofacial Radiology 2019 Imaging Science in Dentistry Vol.49 No.2

        Purpose: The purpose of this study was to investigate variations in velar shape according to age, sex, and race using magnetic resonance imaging (MRI). Materials and Methods: The study sample consisted of 170 participants (85 children, 85 adults) between 4 and 34 years of age. Velar morphology was visually classified using midsagittal MRI scans for each participant by 2 independent raters. Inter- and intra-rater reliability was assessed. Statistical analyses were performed to identify correlations of velar shape with sex, age, and race. Results: The most frequent velar shape was "butt" for both adults(41%) and children (58%) in this study. The least common shapes for adults were "leaf" and "S." The children did not exhibit any "leaf" or "straight" velar shapes. A statistically significant difference was noted for age with respect to velar shape (P=0.014). Sex and race were found to have no significant impact on velar shape in this study. Conclusion: When using MRI to evaluate velar morphology, the "butt" shape was most common in both children and adults. Velar shape varied significantly with age, while race and sex did not have a significant impact.

      • KCI등재

        Weather Conditions Drive the Damage Area Caused by Armillaria Root Disease in Coniferous Forests across Poland

        Paweł Lech,Oksana Mychayliv,Robert Hildebrand,Olga Orman 한국식물병리학회 2023 Plant Pathology Journal Vol.39 No.6

        Armillaria root disease affects forests around the world. It occurs in many habitats and causes losses in the infested stands. Weather conditions are important factors for growth and development of Armillaria species. Yet, the relation between occurrence of damage caused by Armillaria disease and weather variables are still poorly understood. Thus, we used generalized linear mixed models to determine the relationship between weather conditions of current and previous year (temperature, precipitation and their deviation from long-term averages, air humidity and soil temperature) and the incidence of Armillaria-induced damage in young (up to 20 years old) and older (over 20 years old) coniferous stands in selected forest districts across Poland. We used unique data, gathered over the course of 23 years (1987-2009) on tree damage incidence from Armillaria root disease and meteorological parameters from the 24-year period (1986-2009) to reflect the dynamics of damage occurrence and weather conditions. Weather parameters were better predictors of damage caused by Armillaria disease in younger stands than in older ones. The strongest predictor was soil temperature, especially that of the previous year growing season and the current year spring. We found that temperature and precipitation of different seasons in previous year had more pronounced effect on the young stand area affected by Armillaria. Each stand’s age class was characterized by a different set of meteorological parameters that explained the area of disease occurrence. Moreover, forest district was included in all models and thus, was an important variable in explaining the stand area affected by Armillaria.

      • SCISCIESCOPUS

        Vivaldi: A Domain-Specific Language for Volume Processing and Visualization on Distributed Heterogeneous Systems

        Hyungsuk Choi,Woohyuk Choi,Tran Minh Quan,Hildebrand, David G. C.,Pfister, Hanspeter,Won-Ki Jeong IEEE 2014 IEEE transactions on visualization and computer gr Vol.20 No.12

        <P>As the size of image data from microscopes and telescopes increases, the need for high-throughput processing and visualization of large volumetric data has become more pressing. At the same time, many-core processors and GPU accelerators are commonplace, making high-performance distributed heterogeneous computing systems affordable. However, effectively utilizing GPU clusters is difficult for novice programmers, and even experienced programmers often fail to fully leverage the computing power of new parallel architectures due to their steep learning curve and programming complexity. In this paper, we propose Vivaldi, a new domain-specific language for volume processing and visualization on distributed heterogeneous computing systems. Vivaldi's Python-like grammar and parallel processing abstractions provide flexible programming tools for non-experts to easily write high-performance parallel computing code. Vivaldi provides commonly used functions and numerical operators for customized visualization and high-throughput image processing applications. We demonstrate the performance and usability of Vivaldi on several examples ranging from volume rendering to image segmentation.</P>

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