Evaluating Diet and Sleep Quality of Shift and Non-Shift Nurses Using Three-Factor Pittsburgh Sleep Quality Index and Healthy Eating Index-2015

Helvaci Gizem,Aslan Çin Nazlı Nur,Canbulat Şahinde,Yardimci Hülya 대한수면학회 2020 sleep medicine research Vol.11 No.2

Background and ObjectiveaaThe objective of this study was to determine whether there were differences in diet and sleep quality between shift and non-shift nurses. Nurses among healthcare professionals mostly work in shifts. Therefore, they may face many health problems. Changes of their dietary pattern and sleep quality might be among underlying causes for their health risks. MethodsaaThis descriptive and cross-sectional research enrolled 298 nurses working in two hospitals who volunteered to participate in this study. The work schedule of nurses included a non-shift work and a shift-work. Sleep quality was measured with the Pittsburgh Sleep Quality Index (PSQI). Data were analyzed using a three-factor PSQI model. ResultsaaBased on the three-factor PSQI model, scores for sleep efficiency, sleep quality, and daily disturbances were significantly (p < 0.05) higher in shift nurses than in non-shift nurses. Among individuals with good sleep quality, the diet quality of shift nurses was worse (p < 0.05) than that of non-shift nurses. Among individuals with poor sleep quality, there was no significant (p > 0.05) difference in total diet quality score according to shift status. ConclusionsaaShift work was significantly associated with poor sleep quality. Among nurses with good sleep quality, the diet quality of shift nurses was worse than that of non-shift nurses.

BORATE DEPOSITS: AN OVERVIEW and FUTURE FORECAST WITH REGARD TO MINERAL DEPOSITS AND CHEMISTRY

Cahit HELVACI 한국암석학회 2015 한국암석학회 학술발표회 논문집 Vol.2015 No.5

Clinicopathological Features in Bilateral Breast Cancer

Baykara, Meltem,Ozturk, Selcuk Cemil,Buyukberber, Suleyman,Helvaci, Kaan,Ozdemir, Nuriye,Alkis, Necati,Berk, Veli,Koca, Dogan,Coskun, Ugur,Oksuzoglu, Berna,Uncu, Dogan,Arpaci, Erkan,Ustaalioglu, Basak Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.9

Introduction and Purpose: The frequency of bilateral breast cancer is 1.4-11.0% among all breast cancers. It can present as synchronous (SC) or metachronous (MC). Data regarding clinical course of bilateral breast cancer are scarce. In this study, we therefore evaluated demographic, pathological and clinical characteristics, treatments and responses in bilateral breast cancer cases; making distinctions between metachronous-synchronous and comparing with historic one-sided data for the same parameters. Materials and Methods: One hundred fifty bilateral breast cancer cases from ten different centers between 2000 and 2011 were retrospectively scanned. Age of the cases, family history, menopausal status, pathological features, pathological stages, neoadjuvant, surgery, adjuvant and palliative chemotherapy/radiotherapy were examined in the context of the first and second occurrence and discussed with reference to the literature. Results: Metachronous and synchronous groups showed similar age, menopausal status, tumor type, HER2/neu expression; the family history tumor grade, tumor stage, ER-negativity rate, local and distant metastases rates, surgery, adjuvant chemotherapy application rates were identified as significantly different. Palliative chemotherapy response rate was greater in the metachronous group but median PFS rates did not differ between the groups. Conclusion: Although bilateral breast cancer is not frequent, MC breast cancer is different from SC breast cancer by having more advanced grade, stage, less ER expression, more frequent rates of local relapse and distant metastasis and better response to chemotherapy in case of relapse/metastasis.

Detection of Circulating Tumor Cells in Breast Cancer Patients: Prognostic Predictive Role

Turker, Ibrahim,Uyeturk, Ummugul,Sonmez, Ozlem Uysal,Oksuzoglu, Berna,Helvaci, Kaan,Arslan, Ulku Yalcintas,Budakoglu, Burcin,Alkis, Necati,Aksoy, Sercan,Zengin, Nurullah Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.3

A determination of circulating tumor cell (CTC) effectiveness for prediction of progression-free survival (PFS) and overall survival (OS) was conducted as an adjunct to standard treatment of care in breast cancer management. Between November 2008 and March 2009, 22 metastatic and 12 early stage breast carcinoma patients, admitted to Ankara Oncology Training and Research Hospital, were included in this prospective trial. Patients' characteristics, treatment schedules and survival data were evaluated. CTC was detected twice by CellSearch method before and 9-12 weeks after the initiation of chemotherapy. A cut-off value equal or greater than 5 cells per 7.5 ml blood sample was considered positive. All patients were female. Median ages were 48.0 (range: 29-65) and 52.5 (range: 35-66) in early stage and metastatic subgroups, respectively. CTC was positive in 3 (13.6%) patients before chemotherapy and 6 (27.3%) patients during chemotherapy in the metastatic subgroup whereas positive in only one patient in the early stage subgroup before and during chemotherapy. The median follow-up was 22.0 (range: 21-23) and 19.0 (range: 5-23) months in the early stage and metastatic groups, respectively. In the metastatic group, both median PFS and OS were significantly shorter in any time CTC positive patients compared to CTC negative patients (PFS: 4.0 vs 14.0 months, Log-Rank p=0.013; and OS: 8.0 months vs. 20.5 months, Log-Rank p<0.001). OS was affected from multiple visceral metastatic sites (p=0.055) and higher grade (p=0.044) besides CTC positivity (log rank p<0.001). Radiological response of chemotherapy was also correlated with better survival (p<0.001). As a result, CTC positivity was confirmed as a prospective marker even in a small patient population, in this single center study. Measurement of CTC by CellSearch method in metastatic breast carcinoma cases may allow indications of early risk of relapse or death with even as few as two measurements during a chemotherapy program, but this finding should be confirmed with prospective trials in larger study populations.

Poster Session : PS 0612 ; Others ; Successful Intracavitary tPA Treatment of Gastrocnemius Intramuscular Hematoma in a Patient Following Anticoagulant Therapy with Warfarin: Case Report

( Muge Bilge ),( Zafer Unsal Coskun ),( Cengiz Cakan ),( Mine Adas ),( Serife Aysen Helvaci ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

Warfarin is an anticoagulant used in a variety of clinical indications and may rarely cause severe bleeding that can be life-threatening.Although intramuscular bleeding frequently occure secondary to trauma,it can be induced in cases that cause bleeding tendency.Hematoma is often treated with conventional methods.However, surgical decompression can also be applied.Case Report;A 71 year old male patient admitted to our clinic with increased skin temperature, swelling and redness on the right leg.Warfarin was the only drug in the present treatment that cause bleeding tendency.During the physical examination, swelling, skin redness, echymosis, decreased motility, pain with palpation and tenderness were deteceted on the gastrocnemius location of the right leg.There was no other fi nding in the rest systemic examination.Magnetic resonance imaging (MRI) of the right lower limb of the patient showed a mass lesion on posteromedial of right cruris, displacing the medial head of the gastrocnemius muscle laterally(fig 1).Considering the datas of the performed imaging methods and using an ultrasonography-assisted GF-multipurpose drainage pigtale catheter,intracavitary administration of 5 mg tPA and 25 cc serum sale mixture was performed.Subsequently the catheter was clamped for a 25-30 minutes time and spontaneous drainage occured. After the intervention,a compression bandage was done with elastic bandage in order to avoid reloading of the cavity.Ultrasonographic control was performed after each step of the intervention to check a possible presence of an organised hematoma and intervention went on till there was no liquid rest in the location of hematoma. The total recovery was also proved by magnetic resonance imaging after total clinical recovery was deteceted (fig2).This case report represents that the addition of fi brinolytics to the standard drainage techniques is a safe and effective therapy method in organised hematoma as well as abscess complicated with surgery.

Multicenter Evaluation of Patients with Cutaneous Malignant Melanoma in Turkey: MELAS Study

Uysal-Sonmez, Ozlem,Tanriverdi, Ozgur,Esbah, Onur,Uyeturk, Ummugul,Helvaci, Kaan,Bal, Oznur,Yalcintas-Arslan, Ulku,Budakoglu, Burcin,Oksuzoglu, Berna Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.1

Background: Malignant melanoma is a cancer that demonstrates rapid progression and atypical clinically features with a poor prognosis. Aim: This study was performed to determine the clinical characteristics and treatment outcomes of patients with malignant melanoma in Turkey. Methods: The medical records of 98 patients between 2007-2012 at our centers were retrieved from the patient registry. Overall survival (OS) was calculated using the Kaplan-Meier method. Results: In our study, with the median follow-up of all patients with cutaneous MM of 46.3 months, the median OS rate of all cases was 43.6 months and 5-year OS was 48.6%. However, five-year OS rates of patients with localized disease (stage I-II) and node involvement (stage III) were 60.3% and 39.6%, respectively. The median OS of stage IV patients was 8.7 months and 1-year OS rate was 26.2%. We showed that advanced stage, male gender, and advanced age in all patients with MM were significant prognostic factors of OS. Conclusions: Compared with the results of current studies from Western countries, we found similar findings concerning demographical features, histological variables and survival analyses for our patients with cutaneous MM in Turkey.

Prognostic Factors and Adjuvant Treatments for Surgically Treated Cancers of the Biliary Tract: A Multicentre Study of the Anatolian Society of Medical Oncology (ASMO)

Unal, Olcun Umit,Oztop, Ilhan,Assoc, Tugba Kos,Turan, Nedim,Kucukoner, Mehmet,Helvaci, Kaan,Berk, Veli,Sevinc, Alper,Yildiz, Ramazan,Cinkir, Havva yesil,Tonyali, Onder,Demirci, Umut,Aktas, Bilge,Balak Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.22

Background: Biliary tract cancers are rare, and surgical resection is the standard treatment at early stages. However, reports on the benefits of adjuvant treatment following surgical resection are conflicting. This study aimed to evaluate the factors affecting survival and adjuvant treatments in patients with surgically treated biliary tract cancers. Materials and Methods: Patient clinical features, adjuvant treatments, and efficacy and prognostic factor data were evaluated. Survival analyses were performed using SPSS 15.0. Results: The median overall survival was 30.7 months (95% confidence interval [CI], 18.4-42.9 months). Median survival was 19 months (95% CI, 6-33) for patients treated with fluorouracil based chemotherapy and 53 months (95% CI, 33.2-78.8) with gemcitabine based chemotherapy(p=0.033). On univariate analysis, poor prognostic factors for survival were galbladder localization, perineural invasion, hepatic invasion, a lack of adjuvant chemoradiotherapy treatment, and a lack of lymph node dissection. On multivariate analysis, perineural invasion was a poor prognostic factor (p=0.008). Conclusions: Biliary tract cancers generally have poor prognoses. The main factors affecting survival are tumour localization, perineural invasion, hepatic invasion, adjuvant chemoradiotherapy, and lymph node dissection. Gemcitabine-based adjuvant chemotherapy is more effective than 5-fluorouracil-based chemotherapy.