Electrical and Mechanical Properties of Epoxy Composites Reinforced with Kaolin-Coated Basalt Fibers

He-Chen Liu,Yu Sun,Mingjia Zhang,Yun-Peng Liu,Yunfei Yu,Hong Yu 한국섬유공학회 2023 Fibers and polymers Vol.24 No.1

Basalt fiber (BF) is appropriately used for manufacturing insulating rods because of its excellent aging resistance, hightemperature resistance, electrical insulation, and mechanical strength. However, due to the inert structure on the surface ofthe fiber, the close bonding between the fiber and the resin is hindered. The low bonding strength of the fiber/resin interfacewill significantly reduce the mechanical and insulation properties of the composite, which limits its application in electricalequipment such as insulating rods and insulators. Therefore, this paper attempts to improve the surface roughness of BF byusing Kaolin to strengthen the bonding strength between BF and matrix resin, and analyze and study the mechanical and insulationproperties of the composites before and after modification. The Kaolin content coated on BF ranged from 0.5 to 2 wt%,and the composites modified by 1.5wt%Kaolin (1.5-wt%-K-BFRP) exhibited excellent electrical insulation and mechanicalperformance. Compared with untreated BFRP, the electrical breakdown strength and flashover voltage of 1.5-wt%-K-BFRPincreased by 18.49% and 10.69%, elevated to the 20.57 kV/mm and 13.04 kV, respectively, and the dielectric loss decreasedby 49%, down to 0.83%. The above results indicate that modified BFRP has excellent insulation strength and is suitable forthe manufacture of insulating devices. Furthermore, the bending strength, bending modulus, tensile strength, and interlayershear strength of 1.5-wt%-K-BFRP increased by 67.59%, 21%, 14.56%, and 103.7%, respectively, compared with untreatedBFRP, reach to 465.17 MPa, 31.49 GPa, 562.3 MPa, 26.44 MPa.

A Heuristic Algorithm for Alongside Replenishment Scheduling Problem of Ship Fleet with Time Constraint

Yu Peng,He Xue-jun,Ren Ai-di 보안공학연구지원센터 2014 International Journal of Control and Automation Vol.7 No.12

The alongside replenishment scheduling problem with time constraint determining the partition of the ships, the order of replenishment and the allocation of time to the ships at the same time is analyzed. It is equivalent to a multi-stage flow shop scheduling problem with the object of maximizing the effectiveness value of ship fleet. The problem solving process is divided into three steps, and based on the analysis of the three steps, a heuristic algorithm is proposed. The algorithm firstly considers the time allocated to each ship, and then sequences the ships by heuristic rule combining greed with insertion, finally determines the ships partitioning to the port and standard side. Emulating example with different problems’ scale and time constraints shows that the proposed heuristic algorithm is superior to some other algorithms.

Mucin2 is Required for Probiotic Agents-Mediated Blocking Effects on Meningitic E. coli-Induced Pathogenicities

Jing Yi Yu,Xiao Long He,Santhosh Puthiyakunnon,Liang Peng,Yan Li,Li Sha Wu,Wen Ling Peng,Ya Zhang,Jie Gao,Yao Yuan Zhang,Swapna Boddu,Min Long,Hong Cao,Sheng He Huang 한국미생물 · 생명공학회 2015 Journal of microbiology and biotechnology Vol.25 No.10

Branched polymeric prodrug/programmed cell death 4 complexes for combinational cancer therapy

Yu‑Jing He,Lei Xing,Peng‑Fei Cui,Jia‑Liang Zhang,Jian‑Bin Qiao,Cheng‑Qiong Luo,Ge Jiang,Hu‑Lin Jiang 한국약제학회 2017 Journal of Pharmaceutical Investigation Vol.47 No.2

Here, we demonstrate a co-delivery system constructed by integrating chemotherapeutic molecules into branched polymeric prodrug which can condense nucleic acids. Demethylcantharidate (DCA) was chosen as a model drug and premodified through nucleophilic substitution reaction by its two carboxylic groups with allyl chloride. The synthesized intermediate (DCA-dially) was then used to polymerize with tris (2-aminoethyl) amine (TAEA) through progressively ammonolysis reaction. The obtained poly (DCA-alt-TAEA) (DCAT) was used to pack PDCD4 into spherical-like nanoparticles through electrostatic interaction. Gel retardation assays implied that DCAT could integrate DNA at the weight ratio of 1 and protect it from digestion by nuclease. Acid-base titration experiments showed that DCAT obtained preferable buffering capability which was beneficial for the endosomal escape of DCAT/PDCD4 complexes. Cellular tests involving gene transfection efficiency and cytotoxicity indicated that DCA and PDCD4 co-delivered by the complexes significantly and synergistically suppressed the viability of SMMC-7721 cells. These results suggest that integrating chemotherapeutic molecules into nucleic acid-packing polymeric prodrug as cationic polymer/PDCD4 complexes is a highly efficient way to co-deliver chemotherapeutic drugs and nucleic acids for cancer therapy.

Effects of different carbon sources on the phase composition and microstructure of synthesized SiC-B4C composite powders

Yu Cao,Ruyi Deng,Jilin Hu,Jinxiu He,Dapeng Lei,Zhanjun Chen,Yangxi Peng 한양대학교 청정에너지연구소 2023 Journal of Ceramic Processing Research Vol.24 No.2

SiC-B4C composite powders were synthesized by the carbothermal reduction method under an argon atmosphere usingdifferent kinds of carbon sources (carbon black and starch) and silica sol and boric acid as the precursor raw materials. Basedon thermodynamic analysis and calculation, the effects of different carbon sources and reaction temperatures on the mass lossrate, phase composition, and microstructure of SiC-B4C ultrafine composite powders were comparatively studied. Resultsshowed that the optimum conditions for synthesizing SiC-B4C composite powders with carbon black as the carbon source were1550 ºC for 2 h, whereas the optimum conditions for synthesizing SiC-B4C composite powders with starch as the carbon sourcewere 1450 ºC-1550 ºC for 2 h. The powder samples synthesized with carbon black as the carbon source at 1550 ºC were mainlycomposed of flaky, columnar-like, spherical, and irregular polyhedral particles (about 100-200 nm in diameter). Mutualcohesion or agglomeration between particles was minimal. In the powder samples synthesized at 1550 ºC with an excess of 10wt% starch, in addition to a certain amount of flaky, spherical, and other irregular structure particles, a certain amount ofuniform, slender whiskers (about 50-100 nm in diameter) and a certain phenomenon of lap and winding between the whiskerswere noted. The powder samples synthesized at 1550 ºC with an excess of 20 wt% starch had no whisker-like substance.

Finite-time Dynamic Surface Fault-tolerant Control for Hypersonic Vehicle with Mismatched Disturbances

Peng Li,Peng Huang,Chen-Yu He,Xiao-Qing Liu 제어·로봇·시스템학회 2021 International Journal of Control, Automation, and Vol.19 No.7

This paper studies the tracking control problem of hypersonic vehicle in the process of external disturbance, parameters uncertainties and actuator faults. Firstly, a non-triangular velocity and altitude nonlinear subsystem with mismatched disturbances and actuator faults are established based on the feedback linearization model. Secondly, adaptive dynamic surface fault-tolerant controllers are designed for velocity and altitude subsystems by combining nonlinear filter, adaptive control and back-stepping method. Finally, the Lyapunov stability theory and numercial simulation are carried out to verify the availability of the proposed control strategy.

Factors for Endoscopic Submucosal Dissection in Early Colorectal Neoplasms: A Single Center Clinical Experience in China

Yu-Qi He,Xin Wang,Lang Yang,Jian Zhang,Qian Kang,Shan Tang,Peng Jin,Jian-Qiu Sheng,Ai-Qin Li 대한소화기내시경학회 2015 Clinical Endoscopy Vol.48 No.5

Background/Aims: Early colorectal (CR) neoplasm can be cured by endoscopic submucosal dissection (ESD), but clinical experience and factors associated with complications from ESD for CR neoplasms in China have not been reported . Methods: Seventy-eight cases of early CR neoplasm treated with endoscopic resection performed between December 2012 and December 2013 at Beijing Military General Hospital were included. Factors associated with ESD complications and procedure times were evaluated. Results: The en bloc resection rate was 88.5% (69/78), tumor size was 32.1±10.7 mm, and procedure time was 71.8±49.5 minutes. The major complication was perforation, which occurred in 8.97% of the ESD procedures. Multivariate logistic regression analysis indicated that only tumor size (p=0.022) was associated with ESD perforation. Tumor size (p<0.001) and the non-lifting sign (p=0.017) were independent factors for procedure time, and procedure time (p=0.016) was a key factor for en bloc resection. After a median 10 months (range, 4 to 16) of follow-up, no patients had local recurrence. Conclusions: This study indicated that ESD is an applicable method for large early CR neoplasm in the colon and rectum. Tumor size and the non-lifting sign might be considerable factors for increased complication rate and procedural time of ESD.

A Genome-Wide Association Study Reveals Candidate Genes Related to Salt Tolerance in Rice ( <i>Oryza sativa</i> ) at the Germination Stage

Yu, Jie,Zhao, Weiguo,Tong, Wei,He, Qiang,Yoon, Min-Young,Li, Feng-Peng,Choi, Buung,Heo, Eun-Beom,Kim, Kyu-Won,Park, Yong-Jin MDPI 2018 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vol.19 No.10

<P>Salt toxicity is the major factor limiting crop productivity in saline soils. In this paper, 295 accessions including a heuristic core set (137 accessions) and 158 bred varieties were re-sequenced and ~1.65 million SNPs/indels were used to perform a genome-wide association study (GWAS) of salt-tolerance-related phenotypes in rice during the germination stage. A total of 12 associated peaks distributed on seven chromosomes using a compressed mixed linear model were detected. Determined by linkage disequilibrium (LD) blocks analysis, we finally obtained a total of 79 candidate genes. By detecting the highly associated variations located inside the genic region that overlapped with the results of LD block analysis, we characterized 17 genes that may contribute to salt tolerance during the seed germination stage. At the same time, we conducted a haplotype analysis of the genes with functional variations together with phenotypic correlation and orthologous sequence analyses. Among these genes, <I>OsMADS31</I>, which is a MADS-box family transcription factor, had a down-regulated expression under the salt condition and it was predicted to be involved in the salt tolerance at the rice germination stage. Our study revealed some novel candidate genes and their substantial natural variations in the rice genome at the germination stage. The GWAS in rice at the germination stage would provide important resources for molecular breeding and functional analysis of the salt tolerance during rice germination.</P>

H_3PW_12_O40/SiO_2 for sorbitol dehydration to isosorbide: High efficient and reusable solid acid catalyst

Peng Sun,He Huang,Ding Hua Yu,Yi Hu,Zhen Chen Tang,Jiao Jiao Xia,Heng Li 한국화학공학회 2011 Korean Journal of Chemical Engineering Vol.28 No.1

Tungstophosphoric acids (PW) supported on various metal oxides (SiO_2, γ_Al_2O_3, TiO_2, ZrO_2 and CeO_2)were synthesized and used as catalysts for sorbitol dehydration to isosorbide for the first time. 30% PW/SiO_2 exhibited the best catalytic performance for sorbitol dehydration, over which 56% isosorbide selectivity could be gained at a 95% sorbitol conversion at 250℃. The catalytic performance of regenerated 30% PW/SiO_2 catalysts by dichloromethane elution showed no loss after recycling five runs. Characterizations with UV-Vis, XRD, NH3-TPD and thermal analysis techniques revealed that PW had a good dispersion, and the primary Keggin structure was preserved after supporting PW on different supports. The interaction between PW and oxides resulted in different acidity of catalysts,which affected conversion of sorbitol and selectivity for isosorbide. The final acidity order of supported PW catalysts was the following: SiO_2>γ_Al_2O_3>TiO_2 ≈ZrO_2>CeO_2.

Estradiol regulates miR-135b and mismatch repair gene expressions via estrogen receptor-β in colorectal cells

Yu-qi He,Jian-qiu Sheng,Xian-long Ling,Lei Fu,Peng Jin,Lawrence Yen,Jianyu Rao 생화학분자생물학회 2012 Experimental and molecular medicine Vol.44 No.12

Estrogen has anti-colorectal cancer effects which are thought to be mediated by mismatch repair gene (MMR) activity. Estrogen receptor (ER) expression is associated with microRNA (miRNA) expression in ER-positive tumors. However, studies of direct link between estrogen (especially estradiol E2), miRNA expression, and MMR in colorectal cancer (CRC) have not been done. In this study, we first evaluated the effects of estradiol (E2) and its antagonist ICI182,780 on the expression of miRNAs (miR-31, miR-155 and miR-135b) using COLO205, SW480 and MCF-7 cell lines, followed by examining the association of tissue miRNA expression and serum E2 levels using samples collected from 18 colorectal cancer patients. E2inhibited the expressions of miRNAs in COLO205 cells,which could be reversed by E2 antagonist ICI 182.780. The expression of miR-135b was inversely correlated with serum E2 level and ER-β mRNA expression in CRC patients’ cancer tissues. There were significant correlations between serum E2 level and expression of ER-β, miR-135b, and MMR in colon cancer tissue. This study suggests that the effects of estrogen on MMR function may be related to regulating miRNA expression via ER-β, which may be the basis for the anti-cancer effect in colorectal cells.