활동적인 일본 남자에서 노화가 HbAIc에 미치는 영향

Hashimoto 대한당뇨병학회 1995 Diabetes and Metabolism Journal Vol.19 No.4

Occurrence of ELISA Inhibitors, and Inhibitor-free Determination of Cyclobutane Pyrimidine Dimers in Japanese Cypress Leaves

Hashimoto, Tohru,Nakagawa, Noriko,Okano, Michiaki,Nikaido, Osamu Korean Society of Photoscience 2002 Journal of Photosciences Vol.9 No.2

DNA samples extracted from Japanese cypress leaf tissues contain isopropyl alcohol-precipitable, high molecular weight compounds, which interfere ELISA for cyclobutane pyrimidine dimers (CPD). Removal of the compounds is achieved by DEAE ion-exchange column chromatography and improves the ELISA responses of the DNA. When extracting DNA repeatedly from the same leaf tissues, the DNA samples show CPD responses which increase with the order in sequential extraction, and hence for a reliable detennination of DNA lesion a thorough extraction of DNA is required. Clearing these two problems it was demonstrated that CPD level was slightly higher in the leaves of trees growing under full sunlight than in those growing under UBV -cut sunlight.

Japanese Space Policy - Where is she going?

Hashimoto, Yasuaki Korea Society of Air Space Law and Policy 1997 한국항공우주정책·법학회지 Vol.9 No.-

Passing 26 years from 1970 when the first satellite was launched into the orbit, Japan developed and successfully launched H-II from Tanegashima Space Center in 1994. During those period, Japanese space policy has experienced a big shake from independent development to technology import from the US, and back again to independent development. In general, the H-II rocket which was manufactured by 100% domestic technology, brings Japan from the old era (experimental stage) to the new era (practical use stage). Fundamental Policy of Japan's Space Activities, which decides such policy as mentioned, was revised in January, 1996 this year after an interval of 7 years. This revised outline confirms the result of Japanese space technology until present and identifies the future direction and framework of her space activities for a period of coming ten years on the basis of a ong-term perspective towards the 21st century. However, when comparing with the last Fundamental Policy in 1989, there seems no big change in it, and a long-term perspective is also not seen there. The description varies on some important points in international space law, like international cooperation, protection of environment, commercial use, etc. In addition, the immaturity as well as the necessity of broader discussion are felt because neither this Fundamental Policy nor The National Defense Program Outline treated any national and international security matters concerning outer space. Considering the present time when Japan enters into the practical use of outer space, such as application, commercial use and launching service, etc, it is doubtful whether new Fundamental Policy was properly planned or not. It seems necessary to use several measures by which the public opinion, opinions from industry and debate on the security are reflected in the policy making.

Gas-liquid interface treatment in underwater explosion problem using moving least squares-smoothed particle hydrodynamics

Hashimoto, Gaku,Noguchi, Hirohisa Techno-Press 2008 Interaction and multiscale mechanics Vol.1 No.2

In this study, we investigate the discontinuous-derivative treatment at the gas-liquid interface in underwater explosion (UNDEX) problems by using the Moving Least Squares-Smoothed Particle Hydrodynamics (MLS-SPH) method, which is known as one of the particle methods suitable for problems where large deformation and inhomogeneity occur in the whole domain. Because the numerical oscillation of pressure arises from derivative discontinuity in the UNDEX analysis using the standard SPH method, the MLS shape function with Discontinuous-derivative Basis Function (DBF) that is able to represent the derivative discontinuity of field function is utilized in the MLS-SPH formulation in order to suppress the nonphysical pressure oscillation. The effectiveness of the MLS-SPH with DBF is demonstrated in comparison with the standard SPH and conventional MLS-SPH though a shock tube problem and benchmark standard problems of UNDEX of a trinitrotoluene (TNT) charge.

Self-assembling Peptide Scaffolds and Dedifferentiated Fat Cells for Bone Tissue Engineering

Hashimoto Y,Kishimoto N,Momota Y,Omasa T,Kotani J,Takeda S 대한치과재료학회 2011 대한치과기재학회 학술대회 Vol.2011 No.5

Some Considerations on Developments in Reliabili~ Maintainability and Manning Indices for Engine Systems During the Past 30 Years in Japan - and the Future

Hashimoto, T.,Harada, T.,Kume, K. The Korean Society of Marine Engineering 1993 한국마린엔지니어링학회지 Vol.17 No.5

A marine engine system (MES) should be evaluated by not only reliability (R) but also maintainability (M) and manning index (MI), because this system can be recognised as a typical man-machine system. In 1977 at the first ICMES Conference in Paris one of the authors presented a total evaluation of the MES with the three indices, R, M, MI, proving the human ability of detecting faults and defects in this system. This paper describes how the MES has developed from the point of view of the above three indices during the past 30 years in Japan and its problems in the future, and arrives at the following conclusions : the reliability of the MES has developed due to quality control (QC) ; the maintainability of the MES has improved due to education and training ; the manning index of the MES has improved due to Rand M ; the availability of the MES has kept constant due to the decreasing complement onboard, at the rate of one person per year approximately ; and two esimations having the three indices were shown by the SRIC 1990 Data Base in Japan, for the two kinds of subsystems in the developed MES.

Identifying teaching competencies for medical residents using a modified Delphi method

Hashimoto Tadayuki,Kikukawa Makoto 한국의학교육학회 2024 Korean journal of medical education Vol.36 No.1

Purpose: This study aimed to identify the teaching competencies of medical residents.Methods: A modified Delphi study was conducted from January to March 2017. Twenty-four panelists (six medical educators, program directors, chief residents, and residents each) from various facilities in Japan participated in the study. The consensus criterion for this study was that more than 80% of the panelists gave a rating of 6 or higher on the 7-point Likert scale (“not at all important” to “extremely important”) without any comments. The modified Delphi approach resulted in a list of 27 resident teaching competencies after three rounds. These competencies were categorized based on Harden and Crosby’s 12 roles of medical teachers.Results: Our study revealed that, of the 12 roles, residents were primarily viewed as “clinical or practical teachers,” “teaching role models,” “on-the-job role models,” “learning facilitators,” and “student assessors.”Conclusion: The 27 resident teaching competencies indicate the importance of educational proximity for residents as teachers. It is expected that this finding will contribute to competency-based resident-as-teacher education.

Submarine Cable Measurements of Voltage for Current Monitoring in the-Tsushima and in the Tokara Straits

Hashimoto, Yoshio,Tashiro, Akimasa,Shinozaki, Takashige,Ishii, Hiaeo,Kawatate, Kazuo The Korean Society of Oceanography 2002 Journal of the Korean Society of Oceanography Vol.37 No.3

We have been measuring the voltage differences by using submarine cables in the Tsushima and in the Tokara Straits. The aim of these measurements is to estimate the volume transports of the ocean currents through those straits. In this paper, the voltage differences are compared with the corresponding sea level and air pressure differences between straits. Especially in the Tsushima Strait, the voltage difference is consistent with the air pressure difference as well as the sea level difference.

新羅 文書木簡의 기초적 검토 – 신 출토 월성해자 목간을 중심으로

HASHIMOTO Shigeru 경북대학교 영남문화연구원 2021 嶺南學 Vol.- No.77

This paper reviews document wooden tablets of Silla. The term ‘document’ in the broad sense are documents, records and letters prepared by various government offices, but here we deal with the document in the narrow sense on which the sender and receiver are written. In order to clarify the characteristics and the changes in document wooden tablets of Silla, it is important to compare with those of ancient Japan, such as Jeonbaek mokkan. First of all, we will examine the text and contents of the wooden tablets recently unearthed at the moat of the Wolseong Palace. The contents of the three-sided wooden tablet were that a ‘Dangju’, local government official, sent grain to a government official in the capital, and it is presumed that ‘Sobaekin’ came to the capital and reported it. The document wooden tablets of Silla were, just like Japanese Jeonbaek mokkan, presumed to be related to oral communication and mainly used as report to higher officials. At the same time, it is confirmed that there are differences between the two. The sender and date are written on Silla's document, but not on Japanese ones. The shape of Japanese documents are tabular, while Silla’s ones are cylindrical or polyhedrons. It is likely that these morphological features were designed to make it easier to understand that they were documents. In particular, large ones are assumed to have served as passes. ‘Muncheok’ who wrote a wooden tablet of the moat of the Wolseong Palace is same as the government post found in the stone monuments of Namsansinseong fortress, indicating that local residents were responsible for the administration of documents widely in the provinces. And a comparison between the Three Kingdoms Period and the Unification Period reveals a change in the method of date marking. Such a change can be confirmed in ancient Japan too, but there is a difference in the appearance of the change. Such difference is presumed to be due to differences in the method of introducing the political system of China. 본고는 신라의 문서목간을 검토대상으로 한다. 여기서 문서목간이란 여러 관청에서 작성된 문서, 기록, 편지 가운데 수발 관계를 알 수 있는 협의의 문서목간을 말한다. 신라 문서목간의 특징이나 시대적 변화를 밝히기 위해 고대 일본의 문서목간인 前白木簡과 비교하는 것을 중시한다. 먼저 최근에 출토된 월성 해자 목간의 판독문과 내용을 검토했다. 삼면목간은 지방관인 당주가 왕경에 있는 관인에게 곡물을 보냈다는 내용이며 ‘所白人’은 왕경까지 와서 보고한 사람으로 추정된다. 신라 문서목간은 일본의 전백목간처럼 구두전달과 관계된다고 생각되며 주로 上申文書로 사용되었다. 한편 전백목간과 달리 발신자나 날짜를 명기한다는 등 차이점도 확인된다. 목간의 형태도 전백목간은 판자형인데 신라 문서목간은 원주형목간이나 다면목간이다. 이러한 형태적 특징은 문서라는 것을 쉽게 알 수 있도록 의도적으로 만든 것일 가능성이 크다. 특히 크기가 큰 것은 통행증의 역할을 했을 것으로 추정된다. 월성해자 목간을 쓴 文尺은 남산신성비에 나오는 職名과 똑같으며 지방민이 지방에서 널리 문서행정을 담당한 것을 알 수 있다. 그리고 삼국시대와 통일기 문서목간을 비교해 보면 날짜 표기 서식에 변화가 있다. 이러한 변화는 고대 일본에서도 보이는 상황이지만 변화 양상에는 차이가 있다. 이러한 차이는 중국의 율령제를 도입하는 방식의 차이에 기인한 것으로 추정된다.

Risk Factors for Complications after Reconstructive Surgery for Sternal Wound Infection

Hashimoto, Ichiro,Takaku, Mitsuru,Matsuo, Shinji,Abe, Yoshiro,Harada, Hiroshi,Nagae, Hiroaki,Fujioka, Yusuke,Anraku, Kuniaki,Inagawa, Kiichi,Nakanishi, Hideki Korean Society of Plastic and Reconstructive Surge 2014 Archives of Plastic Surgery Vol.41 No.3

Background Although the utility of flaps for the treatment of sternal wound infections following median sternotomy has been reported for 30 years, there have been few reports on the risk factors for complications after reconstruction. The objective of this investigation was to identify factors related to complications after the reconstruction of sternal wound infections. Methods A retrospective analysis of 74 patients with reconstructive surgery after sternal wound infection over a 5-year period was performed. Clinical data including age, sex, body mass index (BMI), comorbidities, bacterial culture, previous cardiac surgery, wound depth, mortality rate, type of reconstructive procedure, and complication rate were collected. Results The patients' BMI ranged from 15.2 to $33.6kg/m^2$ (mean, $23.1{\pm}3.74kg/m^2$). Wound closure complications after reconstructive surgery were observed in 36.5% of the cases. The mortality rate was 2.7%. Diabetes mellitus significantly affected the rate of wound closure complications (P=0.041). A significant difference in the number of complications was seen between Staphylococcus aureus (S. aureus) and coagulase-negative Staphylococci (P=0.011). There was a correlation between harvesting of the internal thoracic artery and postoperative complications (P=0.048). The complication rates of the pectoralis major flap, rectus abdominis flap, omentum flap, a combination of pectoralis major flap and rectus abdominis flap, and direct closure were 23.3%, 33.3%, 100%, 37.5%, and 35.7%, respectively. Conclusions Diabetes mellitus, S. aureus, harvesting of the internal thoracic artery, and omentum flap were significant factors for complications after reconstruction. The omentum flap volume may be related to the complications associated with the omentum flap transfer in the present study.