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RISS 인기검색어
- 검색키워드
- 저자 : Hasan Önal (검색결과 3 건)
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Fatih Ünal,Galip Temir,Hasan Köten 대한기계학회 2018 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.32 No.8
The purpose of this study is to evaluate the experimental performance of a solar assisted vertical ground source heat pump system (VGSHP) for the winter climatic conditions of Mardin, which is in the South-Eastern Anatolia region of Turkey. For this aim, an experimental analysis was performed on solar assisted VGSHP system, which was designed to meet the heating needs of an experimental room, during the heating season (10.01.2013/03.31.2014). The experimentally obtained results were used to calculate energy, exergy and exergoeconomic analyses of the system and its components. The energy efficiency, exergy efficiency and exergoeconomic factors of the entire system were 67.36 %, 27.40 % and 60.51 %, respectively. In this study, the system was proposed for disseminating the use of alternative technologies supported by renewable energy systems and it has been tested for the first time in Mardin to meet its heating needs with convectional systems. The experimental results showed that the proposed solar assisted VGSHP system can be used for residential heating in Mardin and similar regions. As a result, it has been detected that the system is very effective in both reducing energy consumption and decreasing emissions of green-house gases.
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Betül Çelebi-Saltik,Zeynep Haciomeroglu,Didem Kart,Hasan Hüseyin Ünal,Mustafa Özgür Öteyaka 한국섬유공학회 2022 Fibers and polymers Vol.23 No.11
Tissue engineering strategies include successful management of bone injuries with biomaterials to develop bonelikestructures. The production of natural biomaterials for this purpose helps both to ensure tissue integrity and to presentalternative products for clinical purposes. However, natural materials are mostly used together with synthetic or metallicmaterials due to their low stability and mechanical properties for bone tissue regeneration. There is a clinical need formaterial combinations that have both antimicrobial properties and the ability to increase osteogenic induction. This workaims to fabricate a nanofiber scaffold using polyurethane (PU) loaded with natural fish head powder (FHP) fromArgyrosomus regius species and copper (II) chloride (CuCl2) using the electrospinning technique in order to respond to thisclinical need. There has not been any material combination in the literature that contains these compounds, supports bonedifferentiation of stem cells, and prevents bacterial adhesion. To evaluate our composite materials morphology, chemicalstructure, wettability, and thermal analysis were studied with different techniques. Anti-adhesive properties of theStreptococcus mitis (S. mitis) on composite materials were tested with bacterial colonization, and osteogenic inductiveproperties by human bone marrow mesenchymal stem cells (hBMSCs) with and without osteogenic differentiation mediumwere performed with cell viability assay, Alizarin Red staining, Ca deposition and SEM analysis. According to FESEM-EDSand ATR_FTIR data, the additives were highly incorporated into the PU nanofibers. The produced materials had randomlyoriented nanofiber with a porosity of ~72 %. The FHP loaded nanofiber had an average diameter of ~185 nm. The swellingbehavior of FHP-loaded PU roughly decreased for 3, 5, and 7 days due to the hydrophobic character of the sample. Anincreasing percentage of FHP decreased the bacterial colonization of S. mitis. PUn-CuCl2-FHP nanofibers did not exhibit anycytotoxic effect on the hBMSCs. According to Alizarin Red Staining and Ca deposition analysis, stimulation with both thematerial and the osteogenic medium triggered the bone differentiation of the hBMSCs in a combined manner at days-14. Based on the results, it can be deduced that natural fish head is a promising additive material for fabricating bone-likebiomaterials.
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Semra Gürsoy,Tuba Koçkar,Sezen Ugan Atik,Zerrin Önal,Hasan Önal,Erdal Adal 대한소아청소년과학회 2018 Clinical and Experimental Pediatrics (CEP) Vol.61 No.7
Purpose: Type 1 diabetes mellitus (T1DM) is a chronic and immune-mediated disease, which is characterized by the progressive destruction of pancreatic beta cells. T1DM precipitates in genetically susceptible individuals through environmental factors. In this study, we aimed to evaluate the impact of autoimmunity and intestinal colonization of Candida albicans on the development of T1DM. Methods: Forty-two patients newly diagnosed with T1DM and 42 healthy subjects were included in this monocentric study. The basic and clinical characteristics of the patients were recorded. T1DM-, thyroid-, and celiac-associated antibodies were evaluated. Stool cultures for C. albicans were performed to assess whether or not gut integrity was impaired in patients with T1DM. Results: The evaluation of T1DM- and thyroid-associated antibodies showed that the prevalences of islet cell antibodies and antithyroperoxidase positivity were higher in the study patients than in the patients in the control group. Furthermore, the direct examination and culture of fresh stool samples revealed that 50% of the patients with T1DM and 23.8% of the control subjects had fungi (C. albicans). Conclusion: Through this study, we suggest that the presence of intestinal C. albicans colonization at the time of the diagnosis of T1DM may indicate impairment of normal intestinal microbiota. We also suggest that there may be a tendency of T1DM in patients with a high prevalence of intestinal C. albicans.
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