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      • SCIESCOPUSKCI등재

        Effect of Light and Feed Restriction During Rearing on Production Performance of Egg Strain Layers

        Ahsan-ul-haq, Ahsan-ul-haq,Ahmad, Nazir,Rasool, Shahid,Shah, T.H. Asian Australasian Association of Animal Productio 1997 Animal Bioscience Vol.10 No.6

        432 Babcock ISA white leghorn pullets reared for 8 weeks on a standard managemental conditions were exposed to feed/nutrient and light restrictions from 9 to 20 weeks of age. Four feeding regimes i. e. 100, 85 or 70 percent of the recommended allowance and low energy (2,500 Kcal/kg) low protein (13% CP) ration were fed each in the three light regimes i. e. (A) Natural day light starting from 13.24 hr/day at 8 weeks of age and ending 10.41 hr/day at the end of 20 weeks; (B) Constant 11 hr/day light and (C) starting with 13 hr/day at 8 weeks and decreasing @ 20 min/week till 20 weeks of age. At the age of 20 weeks all the birds were shifted to separate cages under uniform lighting feeding and management. During the 21st week light was increased to 12 hr a day and thereafter with an increase of 30 min per week, increased to 16 hr a day at the age of 29 weeks. From 20 weeks onward till 72 week age, all the birds were offered commercial layer rations ad libitum, prepared according to climatic conditions. The results of the study revealed that birds reared under natural and constant light had higher weights than decreasing light, yet they could not out perform during production period. The effect of feed and nutrient restriction, on the other hand, was found significant during rearing as well as production period. The birds exposed to higher level of feed and those exposed to nutrient restriction were lighter in weight. The 100% fed birds laid their first egg at an early age. However, those reared on 85% of the recommendation excelled all other groups in terms of produced number of eggs, egg mass, hen housed and hen day production and net returns.

      • KCI등재

        Household empowerment as the key to eradicate poverty incidence

        Muhammad Abrar ul haq,Mohd Razani Mohd Jali,Gazi Md Nural Islam 한국사회복지학회 2019 Asian Social Work and Policy Review Vol.13 No.1

        The current study aimed to investigate how the household empowerment can potentially reduce the rural poverty incidence. The data were collected through multistage random sampling from the rural households of 24 villages in Southern Punjab, Pakistan. A total of 600 households were selected as sample pool. Face-to- face interviews with the household heads were conducted. The household empowerment was measured through an index that was adopted from Abrar-ul- haq (“An assessment of the role of household empowerment in alleviating poverty in Southern Punjab, Pakistan” (Ph.D. Dissertation), School of Economics, Finance and Banking, Universiti Utara Malaysia, 2017). The binary logit model was used to analyze the impact of household empowerment with other control variables on poverty incidence. The results of the current study confirm the negative nexus between household empowerment and poverty incidence of rural households as the study reported that the probabilities (odds ratio: 0.877) of being poor are reduced by increasing the empowerment (in every aspect, economically, politically, and socially) of the households, and the results are statistically significant at the 1% level of significance. Based on empirical results, this study suggests that household empowerment has significant potential to reduce poverty incidence in the rural areas of Southern Punjab, Pakistan

      • Bioloistic-mediated Transformation of Cotton (Gossypium hirsutum L.): Embryogenic Calli as Explant

        Haq Ikram-ul,Asad Shaheen,Zafar Yusuf The Korean Society of Plant Biotechnology 2005 Plant molecular biology and biotechnology research Vol.7 No.4

        Genetic transformation was carried out by using biolistic gun method. The hypocotyl derived embryogenic calli (explants) of cotton (Gossypium hirsutum L.) cv. Cocker-312 were transformed with a recombinant pGreen II plasmid, in which both, bar (selection marker) and GUS (${\beta}$-glucuronidase) reporter genes were incorporated. Explants were arranged on osmoticum-containing medium (0.5M mannitol) 4 hours prior to and 16 hours after bombardment that was resulted into an increase about >80% for GUS stable expression. 3 days after bombardment, GUS assay was performed, which exhibited, $18.36{\pm}1.00$ calli showed blue spots. The transformed embryogenic calli were cultured on selection medium (@ 6 mg/L basta) for 3 months. The putative transgenic plants were developed via selective somatic embryogenesis (@1.50 mg/L basta); maximum $27.58{\pm}1.25$ somatic embryos were obtained while $17.47{\pm}1.00$ embryos developed into plantlets (@ 0.75mg/L basta). In five independent experiments, up to 7.24% transformation efficiency was recorded. The presence of the transgenes was analyzed by using PCR and southern hybridization analysis. The transgenic plants were developed with in 6-7 months, but mostly transformants were abnormal in morphology.

      • Fabrication of all glass microfluidic device with superior chemical and mechanical resistances by glass molding with vitreous carbon mold

        Haq, Muhammad Refatul,Kim, Young Kyu,Kim, Jun,Ju, Jonghyun,Kim, Seok-min IOP 2019 JOURNAL OF MICROMECHANICS AND MICROENGINEERING - Vol.29 No.7

        <P>A glass microfluidic device with superior chemical and mechanical resistance was fabricated using a cost-effective glass molding process with a vitreous carbon (VC) mold, which was prepared by the carbonization of a replicated polymer precursor. For the development of microfluidic chips with dense microchannels on a large footprint, a defect-free VC mold is essential. In this study, a furan imprinting process, in which a patterned furan layer was imprinted (cured) on a polished furan plate, was established to minimize warpage and gas bubble defects. In addition, the proposed imprinting process markedly reduced the fabrication time of the furan precursor. For feasibility testing, a glass micromixer with a total channel length of 30.6 cm and footprint of 20  ×  20 mm<SUP>2</SUP> was developed by glass molding with the VC mold and thermal fusion bonding. The fabricated glass-molded micromixer was durable at an internal pressure of ~24 MPa, and there was no swelling when used with toluene for an extended time.</P>

      • Deubiquitylating enzymes as cancer stem cell therapeutics

        Haq, Saba,Suresh, Bharathi,Ramakrishna, Suresh Elsevier 2018 Biochimica et biophysica acta, Reviews on cancer Vol.1869 No.1

        <P><B>Abstract</B></P> <P>The focus of basic and applied research on core stem cell transcription factors has paved the way to initial delineation of their characteristics, their regulatory mechanisms, and the applicability of their regulatory proteins for protein-induced pluripotent stem cells (protein-IPSC) generation and in further clinical settings. Striking parallels have been observed between cancer stem cells (CSCs) and stem cells. For the maintenance of stem cells and CSC pluripotency and differentiation, post translational modifications (i.e., ubiquitylation and deubiquitylation) are tightly regulated, as these modifications result in a variety of stem cell fates. The identification of deubiquitylating enzymes (DUBs) involved in the regulation of core stem cell transcription factors and CSC-related proteins might contribute to providing novel insights into the implications of DUB regulatory mechanisms for governing cellular reprogramming and carcinogenesis. Moreover, we propose the novel possibility of applying DUBs coupled with core transcription factors to improve protein-iPSC generation efficiency. Additionally, this review article further illustrates the potential of applying DUB inhibitors as a novel therapeutic intervention for targeting CSCs. Thus, defining DUBs as core pharmacological targets implies that future endeavors to develop their inhibitors may revolutionize our ability to regulate stem cell maintenance and differentiation, somatic cell reprogramming, and cancer stem cells.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Addressing the applications of deubiquitylating enzymes (DUBs) in applied stem cell research and cancer stem cells therapy </LI> <LI> Efficient protein-induced pluripotent stem cells generation by DUBs-mediated extension of half-life of Yamanaka factors </LI> <LI> Discussing the importance of cancer stem cells associated DUBs and developing inhibitors for CSCs-based therapy </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

      • On Interesting Correlation between Meteorological Parameters and COVID-19 Pandemic in Saudi Arabia

        Haq, Mohd Anul,Ahmed, Ahsan International Journal of Computer ScienceNetwork S 2022 International journal of computer science and netw Vol.22 No.4

        The recent outbreak of COVID-19 pandemic cases around the globe has affected Saudi Arabia with around 15, 00,000 confirmed cases within the initial 4 months of transmission. The present investigation analyzed the relationship between daily COVID-19 confirmed cases and meteorological parameters in seventeen cities of KSA. We used secondary published data from the Ministry of Health, KSA daily dataset of COVID-19 confirmed case counts. The meteorological parameters used in the present investigation are temperature, humidity, dew point, and wind speed. Pearson correlation and Spearman rank correlation tests were utilized for data analysis. The incubation period of COVID-19 varies from 1 day to 14 days as per available information. Therefore, an attempt has been made to analyze the effects of meteorological factors with bins of 1, 3, 7, and 14 days. The results suggested that the highest number of correlations (15 cities) was observed for temperature (maximum, minimum, and average) and humidity (12 cities) (minimum and average). The dew point showed relationships for 7 cities and wind showed moderate correlations only for 2 cities. The study results might be useful for authorities and stakeholders in taking specific measures to combat the Covid-19 pandemic.

      • Machine Learning-based Classification of Hyperspectral Imagery

        Haq, Mohd Anul,Rehman, Ziaur,Ahmed, Ahsan,Khan, Mohd Abdul Rahim International Journal of Computer ScienceNetwork S 2022 International journal of computer science and netw Vol.22 No.4

        The classification of hyperspectral imagery (HSI) is essential in the surface of earth observation. Due to the continuous large number of bands, HSI data provide rich information about the object of study; however, it suffers from the curse of dimensionality. Dimensionality reduction is an essential aspect of Machine learning classification. The algorithms based on feature extraction can overcome the data dimensionality issue, thereby allowing the classifiers to utilize comprehensive models to reduce computational costs. This paper assesses and compares two HSI classification techniques. The first is based on the Joint Spatial-Spectral Stacked Autoencoder (JSSSA) method, the second is based on a shallow Artificial Neural Network (SNN), and the third is used the SVM model. The performance of the JSSSA technique is better than the SNN classification technique based on the overall accuracy and Kappa coefficient values. We observed that the JSSSA based method surpasses the SNN technique with an overall accuracy of 96.13% and Kappa coefficient value of 0.95. SNN also achieved a good accuracy of 92.40% and a Kappa coefficient value of 0.90, and SVM achieved an accuracy of 82.87%. The current study suggests that both JSSSA and SNN based techniques prove to be efficient methods for hyperspectral classification of snow features. This work classified the labeled/ground-truth datasets of snow in multiple classes. The labeled/ground-truth data can be valuable for applying deep neural networks such as CNN, hybrid CNN, RNN for glaciology, and snow-related hazard applications.

      • Mulberry leaf water extract inhibits bermudagrass and promotes wheat growth

        Haq, Razia Abdul,Hussain, Mumtaz,Cheema, Zahid Ata,Mushtaq, Muhammad Naeem,Farooq, Muhammad The Korean Society of Weed Science and The Turfgra 2010 Weed Biology and Management Vol.10 No.4

        Allelopathy has the potential to tackle the concerns associated with the indiscriminate use of synthetic herbicides. In search of a natural herbicide, the effects of mulberry (Morus alba) leaf water extracts on bermudagrass (Cynodon dactylon) and wheat (Triticum aestivum) were investigated. Four concentrations of extract (25, 50, 75, and 100%) were compared with a control (distilled water). The results revealed that the pregermination application of 100% mulberry leaf water extract resulted in the complete inhibition of bermudagrass and wheat germination. However, postemergence, two foliar sprays suppressed only the growth of bermudagrass and promoted wheat growth. The effect of the mulberry leaf water extract was concentration dependent. It is evident that the postemergence application of mulberry leaf water extract has the scope for use as natural herbicide for the control of bermudagrass and to promote the growth and yield of wheat.

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