The Influence Factors and Mechanism of Psychosocial Adaptation in Patients with Endocrine Therapy for Prostate Cancer: Based on Society-to-Cells Framework

Hanjing Zhu,Jia Gu,Xia Yuan,Sijie You,Yan Yang 한국간호과학회 2023 한국간호과학회 학술대회 Vol.2023 No.11

Dynamics Modelling and Simulating of Ultra-precision Fly-Cutting Machine Tool

Hanjing Lu,Yuanyuan Ding,Yu Chang,Gangli Chen,Xiaoting Rui 한국정밀공학회 2020 International Journal of Precision Engineering and Vol.21 No.2

Dynamics modelling and simulating are the significant process to improve the machining accuracy of the machine tool. This paper is aimed to model and simulate the ultra-precision fly-cutting machine tool (UFMT) and find the relations between structure parameters and machined surface. In this paper, the multi-rigid-flexible-body dynamics model of the UFMT is firstly built by using transfer matrix method for multibody systems. After deducing overall transfer equation, overall transfer matrix, eigenfrequency equation and dynamics equations, the vibration characteristics and dynamics response of tool-tip are simulated and validated by tests. The machined surface is simulated by transferring displacement between the fly-cutting tool-tip and the workpiece into 3D curve. According to the simulation results, both the air-bearing stiffness of the flying-cutting head and cutting process parameters have effects on the machined surface.

Protection Provided by a Gabexate Mesylate Thermo-Sensitive In Situ Gel for Rats with Grade III Pancreatic Trauma

Hanjing Gao,Qing Song,Faqin Lv,Shan Wang,Yiru Wang,Xiaoyan Li,Yukun Luo,Xingguo Mei,Jie Tang 거트앤리버 소화기연관학회협의회 2017 Gut and Liver Vol.11 No.1

Background/Aims: This study investigated the protection provided by gabexate mesylate thermo-sensitive in-situ gel (GMTI) against grade III pancreatic trauma in rats. Methods: A grade III pancreatic trauma model with main pancreatic duct dividing was established, and the pancreas anatomical diagram, ascites, and serum biochemical indices, including amylase, lipase, C-reactive protein (CRP), interleukin 6 (IL- 6), and tumor necrosis factor-α (TNF-α), were examined. The pancreas was sliced and stained with hematoxylin eosin and subjected to terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) staining. Results: Ascites, serum amylase, lipase, CRP, IL-6, and TNF-α levels were significantly increased in the pancreas trauma (PT) groups with prolonged trauma time and were significantly decreased after GMTI treatment. The morphological structure of the pancreas was loose, the acinus was significantly damaged, the nuclei were irregular and hyperchromatic, and there was inflammatory cell invasion in the PT group compared to the control. After GMTI treatment, the morphological structure of the pancreas was restored, and the damaged acinus and inflammatory cell invasion were decreased compared to the PT group. Moreover, the cell apoptosis index was significantly increased in the PT group and restored to the same levels as the control group after GMTI treatment. Conclusions: GMTI, a novel formulation and drug delivery method, exhibited specific effective protection against PT with acute pancreatitis therapy and has potential value as a minimally invasive adjuvant therapy for PT with acute pancreatitis.

Labia Majora Share

Hanjing Lee,Yan Lin Yap,Jeffrey Jen Hui Low,Jane Lim 대한성형외과학회 2017 Archives of Plastic Surgery Vol.44 No.1

Defects involving specialised areas with characteristic anatomical features, such as the nipple, upper eyelid, and lip, benefit greatly from the use of sharing procedures. The vulva, a complex 3-dimensional structure, can also be reconstructed through a sharing procedure drawing upon the contralateral vulva. In this report, we present the interesting case of a patient with chronic, massive, localised lymphedema of her left labia majora that was resected in 2011. Five years later, she presented with squamous cell carcinoma over the left vulva region, which is rarely associated with chronic lymphedema. To the best of our knowledge, our management of the radical vulvectomy defect with a labia majora sharing procedure is novel and has not been previously described. The labia major flap presented in this report is a shared flap; that is, a transposition flap based on the dorsal clitoral artery, which has consistent vascular anatomy, making this flap durable and reliable. This procedure epitomises the principle of replacing like with like, does not interfere with leg movement or patient positioning, has minimal donor site morbidity, and preserves other locoregional flap options for future reconstruction. One limitation is the need for a lax contralateral vulva. This labia majora sharing procedure is a viable option in carefully selected patients.

Labia Majora Share

Lee, Hanjing,Yap, Yan Lin,Low, Jeffrey Jen Hui,Lim, Jane Korean Society of Plastic and Reconstructive Surge 2017 Archives of Plastic Surgery Vol.44 No.1

Defects involving specialised areas with characteristic anatomical features, such as the nipple, upper eyelid, and lip, benefit greatly from the use of sharing procedures. The vulva, a complex 3-dimensional structure, can also be reconstructed through a sharing procedure drawing upon the contralateral vulva. In this report, we present the interesting case of a patient with chronic, massive, localised lymphedema of her left labia majora that was resected in 2011. Five years later, she presented with squamous cell carcinoma over the left vulva region, which is rarely associated with chronic lymphedema. To the best of our knowledge, our management of the radical vulvectomy defect with a labia majora sharing procedure is novel and has not been previously described. The labia major flap presented in this report is a shared flap; that is, a transposition flap based on the dorsal clitoral artery, which has consistent vascular anatomy, making this flap durable and reliable. This procedure epitomises the principle of replacing like with like, does not interfere with leg movement or patient positioning, has minimal donor site morbidity, and preserves other locoregional flap options for future reconstruction. One limitation is the need for a lax contralateral vulva. This labia majora sharing procedure is a viable option in carefully selected patients.

Higher Prevalence of Metabolic Syndrome in Child-adolescent Patients with Bipolar Disorder

Satyajit Mohite,Hanjing Wu,Shiva Sharma,Luca Lavagnino,Cristian P. Zeni,Terrence T. Currie,Jair C. Soares,Teresa A. Pigott 대한정신약물학회 2020 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.18 No.2

Objective: Previous studies have indicated a convergent and bidirectional relationship between metabolic syndrome (MetS) and bipolar disorder (BD). As most of these studies focused mainly on adults diagnosed with BD, our study aims to investigate and characterize metabolic disturbances in child-adolescents diagnosed with BD. Methods: We retrospectively examined the medical records of psychiatric hospitalizations with admitting diagnosis of BD in child-adolescents (age < 18 years). Body mass index (BMI), lipid profile, fasting blood glucose, and blood pressure were primary variables. National Cholesterol Education Program criteria were used to define MetS. Reference group data was obtained from the National Health and Nutrition Examination Survey study. Statistical analyses included t tests, chi-square tests, and Fisher’s exact tests. Results: We identified 140 child-adolescent patients with BD (mean age = 15.12 ± 1.70 years, 53% male). MetS was significantly more common in BD compared to the reference group: 14% (95% confidence interval [95% CI] 8−20) vs. 6.7% (95% CI 4.1−9.2), p = 0.001 with no significant difference by sex. MetS components were higher in the BD group, particularly BMI ≥ 95% (25% vs. 11.8%, p < 0.001) and high blood pressure (17% vs. 8%, p = 0.05). Moreover, female patients had lower odds of high blood pressure (odds ratio = 0.24 [95% CI 0.08−0.69], p = 0.005). Conclusion: Compared with the general child-adolescent population, the prevalence of MetS was significantly higher in patients with BD of same age. This reiterates the notion of an increased risk of MetS in patients diagnosed with BD; and thus, further exploration is warranted.

Characterization of phytochemical profile of rhizome of artificial cultured Polygonatum sibiricum with multiple rhizome buds

Cheng Weiqing,Pan Zhibin,Zheng Hanjing,Luo Gelian,Liu Zhibin,Xu Suli,Lin Junhan 한국응용생명화학회 2023 Applied Biological Chemistry (Appl Biol Chem) Vol.66 No.-

Rhizome of Polygonatum sibiricum is both a renowned traditional Chinese remedy and a commonly consumed delicacy. Due to the escalating demand and excessive overexploitation, there has been a growing interest in the artificial cultivation of this plant in recent years. To assess the therapeutic benefits of artificially cultivated P. sibiricum, it is crucial to identify and classify its phytochemical components, which are the primary bioactive compounds found in its rhizome. In this study, the phytochemical profile of an artificially cultivated P. sibiricum rhizomes with multiple rhizome buds (ACM) was characterized by using untargeted UHPLC-Q-Orbitrap-MS based approach. In addition, two-wild-types P. sibiricum rhizomes, namely the wild-type with multiple rhizome buds (WTM) and the wild-type with single rhizome bud (WTS), were used for comparison. A total of 183 phytochemicals, including 20 alkaloids, 48 flavonoids, 33 phenolic acids, and 82 terpenoids, were tentatively identified. Generally, the phytochemical profile of ACM was comparable to that of WTM and WTS. In specific, most of the identified alkaloids and phenolic acids, and approximately half of the identified terpenoids, were not significantly different. Notably, several phytochemicals with potent therapeutic properties, such as epiberberine, laetanine, sinapic acid, curcumenol, were present in ACM. Additionally, artificial cultivation increased the abundance of geniposide and naringenin, which have been linked to cardioprotective effects. These findings provide valuable insights for the future utilization of artificially cultivated P. sibiricum.

The Effect of Adapted Aquatic Activity for Children with Cerebral Palsy in School Age

( Xiaohui Hou ),( Yanqing Fen ),( Zeming Ma ),( Hanjing ),( Yuedan Wu ),( Xiaodong Tian ) 한국체육학회 2015 국제스포츠과학 학술대회 Vol.2015 No.1

Objective: To observe the effect of adapted aquatic activity in the role of rehabilitation for children with cerebral palsy in school age. Methods: Twenty-four spastic cerebral palsy children of Guangzhou Cerebral Palsy Rehabilitation School were selected as subjects. These subjects were divided into the control group (regular rehabilitation therapy, RRT, n=12) and the experimental group (regular rehabilitation plus adapted aquatic activity with Halliwick technique, APA n=12). GMFM-88, the Berg balance scale, BMI and sit and reach were measured before and after the treatment. Results: After treatment, GMFM-88 total scores, Berg Balance Scale scores ,Lung`s capacity, sit and reach of APA group increased significantly than before, P<0.05. The RRT group increased too, but the difference was not significant. Half of experiment group can swimming 50-100m independently after 4 months training. There was no significant difference of BMI, sit and reach,GMFM-88 total scores, Berg Balance Scale scores between two groups after treatment (P>0.05), except lung`s capacity of APA group was significant higher than the control group (P < 0.05). Conclusion: Halliwick technical is an effective method to guide APA for school-aged children with cerebral palsy. APA can effectively enhance the gross motor function, balance, flexibility and respiratory capacity and it could be an effective method with other method for school-aged children with cerebral palsy to achieve life-long sport and rehabilitation. But how long to achieve significant effect still need to more research.

The superior lateral genicular artery flap for reconstruction of knee and proximal leg defects

O-Wern Low,Tian Fu Loh,Hanjing Lee,Yan Lin Yap,Jane Lim,Thiam Chye Lim,Vigneswaran Nallathamby 대한성형외과학회 2022 Archives of Plastic Surgery Vol.49 No.1

Reconstruction of defects around the knee region requires thin and pliable skin. The superior lateral genicular artery (SLGA) flap provides an excellent alternative to muscle-based flaps. The anatomy and the surgical techniques of the SLGA flap were reviewed and the results of cases using the SLGA flap for coverage of knee and proximal leg defects were analyzed. SLGA flaps were performed in two cases and followed up for at least 6 months. Twelve articles on the use of the SLGA flap were also identified. A review of 39 cases showed that the mean diameter of the perforator supplying the skin of the flap was 1.04 mm, while the mean diameter of the SLGA at its origin was 1.78 mm. The mean length of the pedicle measured from the origin of the popliteal artery was 7.44 cm. The average dimensions of the flap were 14.8×6.6 cm with primary closure of the donor site in 61.5% of cases. Of these cases, 38.5% were due to trauma, 23.1% were post-burn complications, 12.8% were defects after resection of tumors, and 10.3% were for ulcers post-bursectomy. The most common complication was flap tip necrosis. All studies reported favorable outcomes with complete wound healing.

Extensive Necrotizing Fasciitis after Fat Grafting for Bilateral Breast Augmentation: Recommended Approach and Management

Chong Han Pek,Jane LIM,Hui Wen Ng,Hanjing Lee,Wei Chen ONG,Anthony Tun Lin Foo,Chwee Ming Lim,Mark Thong,Sandeep Jacob Sebastin,Thiam Chye LIM 대한성형외과학회 2015 Archives of Plastic Surgery Vol.42 No.3