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The harmful effect of very low lead exposure on neuro-cognitive development in 6 month old infants
Eun-Hee Ha(하은희),Surabhi Shah,Byung-Mi Kim(김병미),HyeSook Park(박혜숙),Yun-Chul Hong(홍윤철),Mina Ha(하미나),Yangho Kim(김양호),Boong-Nnyun Kim(김붕년),Eunjeong Kim(김은정),Eun-Kyo Park(박은교) 환경독성보건학회 2013 한국독성학회 심포지움 및 학술발표회 Vol.2013 No.10
Personal Exposure to Total VOC Is Associated With Symptoms of Atopic Dermatitis in Schoolchildren
Ha Eun Kyo,Kim Ju Hee,Park Dawon,Lee Eun,Lee Seung Won,Jee Hye Mi,Shin Youn Ho,Han Man Yong 대한의학회 2022 Journal of Korean medical science Vol.37 No.8
Background: The urinary levels of volatile organic compound (VOC) metabolites provide individual exposure levels compared to data obtained by measuring these compounds in ambient air. We aimed to investigate the association between personal urinary concentrations of VOC metabolites and symptoms of atopic dermatitis in schoolchildren. Methods: Nine urinary VOC metabolites were analyzed from urine samples of 149 children. Diagnosis of atopic dermatitis was determined using standardized questionnaires. Pediatricians visited the schools and rated the severity of symptoms using the SCORing Atopic Dermatitis (SCORAD) in all children. Results: Forty-five children (30.2%) had atopic dermatitis based on the International Study of Asthma and Allergies in Childhood (ISAAC) results and 35 children (23.8%) had symptoms of atopic dermatitis with positive SCORAD index values (defined as SCORAD ≥ 5). Children with benzylmercapturic acid detected in personal urines were associated with presence of atopic dermatitis and positive SCORAD index values. Children in the highest quartile of mandelic acid concentration were associated with presence of atopic dermatitis and positive SCORAD results. Conclusion: Personal exposure to VOCs, as indicated by urinary levels of VOC metabolites, was associated with presence of atopic dermatitis and the SCORAD index value.