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      • KCI등재

        Genome-wide identification and analysis of MIKC-type MADS-box genes expression in Chimonanthus salicifolius

        Gui Fang-Fang,Jiang Ge-Ge,Bin Dong,Zhong Shi-Wei,Xiao Zheng,Qiu Fang,Wang Yi-Guang,Yang Li-Yuan,Zhao Hongbo 한국유전학회 2023 Genes & Genomics Vol.45 No.9

        Background MIKC type MADS-box transcription factors are one of the largest gene families and play a pivotal role in flowering time and flower development. Chimonanthus salicifolius belongs to the family Calycanthaceae and has a unique flowering time and flowering morphology compared to other Chimonanthus species, but the research on MIKC type MADS-box gene family of C. salicifolius has not been reported. Objective Identification, comprehensive bioinformatic analysis, the expression pattern of MIKC-type MADS-box gene family from different tissues of C. salicifolius. Methods Genome-wide investigation and expression pattern under different tissues of the MIKC-type MADS-box gene family in C. salicifolius, and their phylogenetic relationships, evolutionary characteristics, gene structure, motif distribution, promoter cis-acting element were performed. Results A total of 29 MIKC-type MADS-box genes were identified from the whole genome sequencing. Interspecies synteny analysis revealed more significant collinearity between C. salicifolius and the magnoliids species compared to eudicots and monocots. MIKC-type MADS-box genes from the same subfamily share similar distribution patterns, gene structure, and expression patterns. Compared with Arabidopsis thaliana, Nymphaea colorata, and Chimonanthus praecox, the FLC genes were absent in C. salicifolius, while the AGL6 subfamily was expanded in C. salicifolius. The selectively expanded promoter (AGL6) and lack of repressor (FLC) genes may explain the earlier flowering in C. salicifolius. The loss of the AP3 homologous gene in C. salicifolius is probably the primary cause of the morphological distinction between C. salicifolius and C. praecox. The csAGL6a gene is specifically expressed in the flowering process and indicates the potential function of promoting flowering. Conclusion This study offers a genome-wide identification and expression profiling of the MIKC-types MADS-box genes in the C. salicifolius, and establishes the foundation for screening flowering development genes and understanding the potential function of the MIKC-types MADS-box genes in the C. salicifolius.

      • Vitrification of Dry Wastes From Nuclear Power Plants in China

        Guang Fang,Xiujian Zhao,Kai Xu 한국방사성폐기물학회 2023 한국방사성폐기물학회 학술논문요약집 Vol.21 No.1

        With the rapid growth of nuclear power in China, a large number of dry wastes, which mainly include the high efficiency particulate air filters (glass fiber), cotton, polyethylene, and absorbent paper with low-level radioactivity and high volume, will be produced during the operation and maintenance of the nuclear power plants. Thermal plasma treatment is a world acceptable technology to incinerate and immobilize radioactive wastes, owing to the high volume reduction factor and the excellent chemical durability of the vitrified waste form. China has developed thermal plasma technology for the treatment of dry wastes from nuclear power plants for more than 15 years and the pilot plant has been constructed. This work will concentrate on the formulation of waste glass fiber to adapt to the vitrification process. A three-component (glass fiber-CaO-Na2O) constrained-region mixture experiment was designed and their viscosity data was mainly studied. The quadratic Scheff? model was used to plot the component effect on melting temperature. The retentions of simulated nuclides, such as Co, Sr, and Cs in the glasses were analyzed. In addition, the glass fiber as a glass matrix to immobilize residual ashes from the thermal plasma gasification of cotton, polyethylene, and absorbent paper was investigated as well.

      • KCI등재

        The potential molecular effects of bursal septpeptide II on immune induction and antitumor activity

        Guang Fang Zhou,Qing Tao Liu,Bin Zhou,Ya Feng Qiu,Xiao Dong Liu,Zhi Yong Ma,Xiu Li Feng,Rui Bing Cao,Pu Yan Chen 대한수의학회 2015 Journal of Veterinary Science Vol.16 No.3

        The bursa of Fabricius (BF) is the acknowledged central humoral immune organ in birds. Bursal septpeptide II (BSP-II) is animmunomodulatory bioactive peptide isolated from BF. To understand the effects of BSP-II on immune induction, gene expression profilesof hybridoma cells treated with BSP-II were evaluated. Pathway analysis showed that regulated genes were involved in cytokine-cytokinereceptor interactions, T cell receptor signaling pathway, and pathway in cancer. It was observed that BSP-II reduced tumor cells proliferationand stimulated p53 expression. These results indicate potential mechanisms underlying the effects of the humoral immune system on immuneinduction, including antitumor activities. Our study has provided a novel insight into immunotherapeutic strategies for treating human tumors.

      • KCI등재

        Microwave-assisted Approach for the Rapid Enzymatic Digestion of Rapeseed Meal

        Ju-Fang Li,Fang Wei,Lu-Lu Guo,Gang-You Yuan,Feng-Hong Huang,Mu-Lan Jiang,Yuan-Di Zhao,Xu-Yan Dong,Guang-Ming Li,Hong Chen 한국식품과학회 2010 Food Science and Biotechnology Vol.19 No.2

        This study demonstrates the use of a new microwave-assisted approach for accelerating the enzymatic digestion of rapeseed meal. The effects of different microwave parameters, such as the time, temperature, and power level, on the degree of hydrolysis (DH) were investigated by using response surface methodology (RSM). The maximum predicted DH value (10.2%) was in good agreement with the value obtained experimentally using an alkaline protease, which was 12.57% under optimal conditions. In only 7 min, the microwave-assisted method achieved a DH value similar to that obtained by the conventional enzymatic digestion method (4 hr). Therefore,this new technique for rapid enzymatic digestion will improve the application of rapeseed meal in the preparation of protein hydrolysates for use in food and feed.

      • Lack of any Prognostic Value of Body Mass Index for Patients Undergoing Chemoradiotherapy for Esophageal Squamous Cell Carcinoma

        Zhang, Fang,Wang, Chuan-Sheng,Sun, Bo,Tian, Guang-Bo,Cao, Fang-Li,Cheng, Yu-Feng Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.7

        Background: The relationship between body mass index(BMI) and outcomes after chemoradiotherapy(CRT) has not been systematically addressed. The purpose of this study was to evaluate the effect of BMI on survival in patients with esophageal squamous cell carcinoma (ESCC). Materials and Methods: Sixty ESCC cases were retrospectively reviewed in this study. Patient overall survival(OS) and disease-free survival (DFS) were compared between two groups (BMI< $24.00kg/m^2$ and $BMI{\geq}24.00kg/m^2$). Results: There were 41 patients in the low/normal BMI group (BMI< $24.00kg/m^2$) and 19 in the high BMI group ($BMI{\geq}24.00kg/m^2$). No significant differences were observed in patient characteristics between these. We found no difference in 2-year OS and DFS associated with BMI (p=0.763 for OS; p=0.818 for DFS) using the Kaplan-Meier method. Univariate analysis revealed that higher clinical stage was prognostic for worse 2-year OS and DFS, metastasis for 2-year OS, lymph node status for 2-year DFS, while age, gender, smoking, drinking, tumor location and BMI were not prognostic. There were no differences in the 2-year OS (hazard ratio=1.117; p=0.789) and DFS(hazard ratio=1.161; p=0.708) between BMI groups in multivariate analysis, whereas we found statistical differences in the 2-year OS and DFS associated with clinical stage, gender and tumor infiltration (p<0.04), independent of age, smoking, drinking, tumor location, the status of lymph node metastases and BMI. Conclusions: BMI was not associated with survival in patients with ESCC treated with CRT as primary therapy. BMI should not be considered a prognostic factor for patients undergoing CRT for ESCC.

      • KCI등재

        Virtual Queue Based QoS Layered Vertical Mapping in Wireless Networks

        ( Shu-guang Fang ),( Ri-zhao Tang ),( Yu-ning Dong ),( Hui Zhang ) 한국인터넷정보학회 2014 KSII Transactions on Internet and Information Syst Vol.8 No.6

        Wireless communication is one of most active areas in modern communication researches, QoS (Quality of Service) assurance is very important for wireless communication systems design, especially for applications such as streaming video etc., which requires strict QoS assurance. The modern wireless networks multi-layer protocol stack structure results in QoS metrics layered and acting in cascade and QoS metrics vertical mapping between protocol layers. Based on virtual buffer between protocol layers and queuing technology, a unified layered QoS mapping framework is proposed in this paper, in which we first propose virtual queue concept, give a novelty united neighboring protocol layers QoS metric mapping framework, and analysis method based on dicerete-time Markov chain, and numerical results show that our proposed framework represents a significant improvement over previous model.

      • 기업평판에 따른 기업위기 대응전략에 관한 연구

        방광수(Fang Guang zhu) 한국비영리학회 2016 한국비영리연구 Vol.15 No.2

        본 연구는 Kim et al.(2004)과 Ferrin et al.(2007), 그리고 Sung et al.(2013)의 연구에 기반을 하여, 기업평판에 따라 능력 위기와 정직성 위기에 대한 대응전략의 효과를 고찰하였다. 분석결과, 우선 위기유형이 기업태도에 미치는 영향에 있어서, 기업역량과 관련된 능력 위기는 기업의 윤리·도덕성과 관련된 정직성 위기보다 기업태도에 더 긍정적인 것으로 나타났다. 그리고 위기 상황에서 대응전략이 기업태도에 미치는 영향에 있어서, 사과전략이 침묵전략과 부인전략보다 더 효과적인 것으로 나타났다. 게다가 본 연구에서는 위기유형, 대응전략, 기업평판 간 상호작용효과를 살펴보았으며, 분석결과 위기유형과 대응전략 간에 기업태도에 통계적으로 유의미한 영향이 있는 것으로 나타났다. 구체적으로 위기유형에 관계없이 사과하는 것이 가장 바람직한 전략으로 나타났다. The current study expands on the research of Ferrin et al.(2007) and Sung et al.(2013) by examining how companies repair corporate attitude after crisis. In Experiment findings, statistically insignificant result is a three-way interaction effect on corporate reputations, crisis types and response strategies, regardless of the type of crisis apology strategy was the most effective strategy. In other words, It can be seen that the severity issues on corporate behavior than the issue of trust.

      • Therapeutic Regimens and Prognostic Factors of Brain Metastatic Cancers

        Song, Wen-Guang,Wang, Yi-Feng,Wang, Rui-Lin,Qu, Yin-E,Zhang, Zhi,Li, Guo-Zhong,Xiao, Ying,Fang, Fang,Chen, Hong Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.2

        Objective: This work aims to investigate the therapeutic regimen of brain metastatic cancers and the relationship between clinical features and prognosis. Methods: Clinical data of 184 patients with brain metastatic cancers were collected and analysed for the relationship between survival time and age, gender, primary diseases, quantity of brain metastatic foci, their position, extra cranial lesions, and therapeutic regimens. Results: The average age of onset was 59.1 years old. The median survival time (MST) was 15.0 months, and the patients with breast cancer as the primary disease had the longest survival time. Females had a longer survival time than males. Patients with meningeal metastasis had extremely short survival time. Those with less than 3 brain metastatic foci survived longer than patients with more than 3. The MST of patients receiving radiotherapy only and the patients receiving chemotherapy only were all 10.0 months while the MST of patients receiving combination therapy was 16.0 months. Multiple COX regression analysis demonstrated that gender, primary diseases, and quantity of brain metastatic foci were independent prognostic factors for brain metastatic cancers. Conclusions: Chemotherapy is as important as radiotherapy in the treatment of brain metastatic cancer. Combination therapy is the best treatment mode. Male gender, brain metastatic cancers originating in the gastrointestinal tract, more than 3 metastatic foci, and involvement of meninges indicate a worse prognosis.

      • KCI등재

        On Bipartite Consensus of Bounded Confidence Models for Opinion Dynamics

        Guang He,Jing Liu,Yanlei Wu,Jian-an Fang 제어·로봇·시스템학회 2020 International Journal of Control, Automation, and Vol.18 No.2

        In this paper, the bipartite consensus problem is investigated for bounded confidence (BC) models. Different from the existing results oncerning clustering characteristic of BC models, we investigate under which circumstances BC models can achieve bipartite consensus. About the classic BC model, we obtain a sufficient and necessary condition for bipartite consensus problem. For the signed BC model, several bipartite consensus criteria are obtained. The obtained criteria reveal that the dynamic of the signed BC model more dependents on the initial opinions. Finally, several examples are provided to illustrate the effectiveness of the obtained results.

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