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- 저자 : Gu Yan (검색결과 131 건)
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Gu Yan,Sun Jianhua,Fu Xiuwei 대한전기학회 2023 Journal of Electrical Engineering & Technology Vol.18 No.2
Given the importance of synchronization in chaotic systems, this paper presents a new approach to achieve this goal. Simultaneous consideration of time-varying delays, disturbances, uncertainties, and nonlinear terms in a fractional order chaotic system poses a fundamental challenge for achieving the synchronization goal and this paper presents a novel complex approach resulting from neural network and sliding mode approaches to overcome it. The Chebyshev neural network has been used to estimate the delayed nonlinear functions as well as the uncertain parts of the fractional order chaotic system, and the robust sliding mode technique has been considered to ensure stability against the effects of multiple inconveniences. Finally, simulation and comparison in MATLAB environment confirms the efficiency and ability of the proposed scheme in achieving the goal of robust synchronization despite the uncertainty, variable time delay, disturbance and nonlinear terms.
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On the weak Artinianness and minimax generalized local cohomology modules
Yan Gu 대한수학회 2013 대한수학회보 Vol.50 No.6
Let R be a commutative Noetherian ring, I an ideal of R, M and N two R-modules. We characterize the least integer i such that Hi I (M,N) is not weakly Artinian by using the notion of weakly filter regular sequences. Also, a local-global principle for minimax generalized local cohomology modules is shown and the result generalizes the corresponding result for local cohomology modules.
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A LINE SEARCH TRUST REGION ALGORITHM AND ITS APPLICATION TO NONLINEAR PORTFOLIO PROBLEMS
Gu, Nengzhu,Zhao, Yan,Gao, Yan The Korean Society for Computational and Applied M 2009 Journal of applied mathematics & informatics Vol.27 No.1
This paper concerns an algorithm that combines line search and trust region step for nonlinear optimization problems. Unlike traditional trust region methods, we incorporate the Armijo line search technique into trust region method to solve the subproblem. In addition, the subproblem is solved accurately, but instead solved by inaccurate method. If a trial step is not accepted, our algorithm performs the Armijo line search from the failed point to find a suitable steplength. At each iteration, the subproblem is solved only one time. In contrast to interior methods, the optimal solution is derived by iterating from outside of the feasible region. In numerical experiment, we apply the algorithm to nonlinear portfolio optimization problems, primary numerical results are presented.
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Reflectance estimation for infrared and visible image fusion
( Yan Gu ),( Feng Yang ),( Weijun Zhao ),( Yiliang Guo ),( Chaobo Min ) 한국인터넷정보학회 2021 KSII Transactions on Internet and Information Syst Vol.15 No.8
The desirable result of infrared (IR) and visible (VIS) image fusion should have textural details from VIS images and salient targets from IR images. However, detail information in the dark regions of VIS image has low contrast and blurry edges, resulting in performance degradation in image fusion. To resolve the troubles of fuzzy details in dark regions of VIS image fusion, we have proposed a method of reflectance estimation for IR and VIS image fusion. In order to maintain and enhance details in these dark regions, dark region approximation (DRA) is pro-posed to optimize the Retinex model.With the improved Retinex model based on DRA, quasi-Newton method is adopted to estimate the reflectance of a VIS image. The final fusion out-come is obtained by fusing the DRA-based reflectance of VIS image with IR image. Our method could simultaneously retain the low visibility details in VIS images and the high con-trast targets in IR images. Experiment statistic shows that compared to some advanced ap-proaches, the proposed method has superiority on detail preservation and visual quality.
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Gu, Yiren,Zhou, Rui,Jin, Long,Tao, Xuan,Zhong, Zhijun,Yang, Xuemei,Liang, Yan,Yang, Yuekui,Wang, Yan,Chen, Xiaohui,Gong, Jianjun,He, Zhiping,Li, Mingzhou,Lv, Xuebin Asian Australasian Association of Animal Productio 2020 Animal Bioscience Vol.33 No.5
Objective: We investigated the temporal expression profiles of long noncoding RNA (lncRNA) and mRNA in the peripheral blood of pigs during development and identified the lncRNAs that are related to the blood-based immune system. Methods: Peripheral blood samples were obtained from the pigs at 0, 7, 28, and 180 days and 2 years of age. RNA sequencing was performed to survey the lncRNA and mRNA transcriptomes in the samples. Short time-series expression miner (STEM) was used to show temporal expression patterns in the mRNAs and lncRNAs. Gene ontology and Kyoto encyclopedia of genes and genomes analyses were performed to assess the genes' biological relevance. To predict the functions of the identified lncRNAs, we extracted mRNAs that were nearby loci and highly correlated with the lncRNAs. Results: In total of 5,946 lncRNA and 12,354 mRNA transcripts were identified among the samples. STEM showed that most lncRNAs and mRNAs had similar temporal expression patterns during development, indicating the expressional correlation and functional relatedness between them. The five stages were divided into two classes: the suckling period and the late developmental stage. Most genes were expressed at low level during the suckling period, but at higher level during the late stages. Expression of several T-cell-related genes increased continuously during the suckling period, indicating that these genes are crucial for establishing the adaptive immune system in piglets at this stage. Notably, lncRNA TCONS-00086451 may promote blood-based immune system development by upregulating nuclear factor of activated T-cells cytoplasmic 2 expression. Conclusion: This study provides a catalog of porcine peripheral blood-related lncRNAs and mRNAs and reveals the characteristics and temporal expression profiles of these lncRNAs and mRNAs during peripheral blood development from the newborn to adult stages in pigs.
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Gu, Ming,Li, Su-Yi,Huang, Xin-En,Lin, Yan,Cheng, Hong-Yan,Liu, Lin Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.11
Objective: This study was performed to evaluated the efficacy and safety of continuous infusional paclitaxel and 5-Fu as first-line chemotherapy in patients with advanced esophageal squamous cell cancer (ESCC). Methods: A total of 22 patients with advanced esophageal squamous cell cancer with no indications for surgery and radiation therapy, or recurrent patients were enrolled from October 2008 to November 2010. All were treated with PTX 20 $mg/m^2$ was administered through a 16 hours continuous intravenous infusion on days 1 to 3, 8 and 9. DDP 3.75 $mg/m^2$ was given on days 1 to 4 and 8 to 11, continuous infusional 5-FU over 24-hours on days 1 to 5 and 8 to 12 at a dose of 375 $mg/m^2$, and folacin 60 mg orally synchronized with 5-Fu. The treatment was repeated every 21 days for at least two cycles. Results: 22 cases of all enrolled patients could be evaluated for the effect of treatment: 2 cases were CR, 9 cases PR, 5 cases SD and 2 cases PD, giving an overall response rate of 68.2%(15/22). The median time to progression was 7.0 months. The adverse reactions related to chemotherapy were tolerable; the most common toxic effects were marrow depression, alopecia, and fatigue. Conclusion: Low-dose continuous infusional PTX over 16-hours and 5-fu over 24-hours is a promising regimen with good tolerability in treating patients with advanced esophageal squamous cell cancer.
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Yan Cheng,Youjun Feng,Ping Luo,Jiang Gu,Shu Yu,Wei-jun Zhang,Yan-qing Liu,Qing-xu Wang,Quan-ming Zou,Xu-hu Mao 한국미생물학회 2009 The journal of microbiology Vol.47 No.4
Shiga toxin 2 (Stx2) is a major virulence factor for enterohemorrhagic Escherichia coli (EHEC), which is encoded by λ lysogenic phage integrated into EHEC chromosome. Stx2A1, A1 subunit of Stx2 toxin has gathered extensive concerns due to its potential of being developed into a vaccine candidate. However, the substantial progress is hampered in part for the lack of a suitable in vitro expression system. Here we report use of the prokaryotic system pET-28a::espA-Stx2A1/BL21 to carry out the fusion expression of Stx2A1 which is linked to E. coli secreted protein A (EspA) at its N-terminus. Under the IPTG induction, EspA- Stx2A1 fusion protein in the form of inclusion body was obtained successfully, whose expression level can reach about 40% of total bacterial protein at 25°C, much higher than that at 37°C. Western blot test suggested the refolded fusion protein is of excellent immuno-reactivity with both monoclonal antibodies, which are specific to EspA and Stx2A1, respectively. Anti-sera from Balb/c mice immunized with the EspA-Stx2A1 fusion protein were found to exhibit strong neutralization activity and protection capability in vitro and in vivo. These data have provided a novel feasible method to produce Stx2A1 in large scale in vitro, which is implicated for the development of multivalent subunit vaccines candidate against EHEC O157:H7 infections.
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( Yan Zhang ),( Fekete Gusztav ),( Yaodong Gu ) 한국체육학회 2016 국제스포츠과학 학술대회 Vol.2016 No.1
Introduction: The high-heel design has been remaining one of the dominant features of women’s footwear. Social and fashion customs encourage the continued use of high-heel shoes (Hong et al., 2005) despite of detrimental effects on the musculoskeletal system, such as lower back pain, ankle sprains, foot pain, hallux valgus and increased predisposition toward degenerative knee osteoarthritis (Barkema, Derrick, & Martin, 2012; Chien et al., 2014; Dawson et al., 2002; Gu et al., 2014). The purpose of this study was to clarify differences in lower limb kinematics and GRF between EW and IEW during moderate high-heel jogging and running. It was hypothesized that EW would show faster self-select speeds of jogging and running than IEW; EW would decrease joint instability while increase GRF in comparison with IEW; changes of lower limb joints (range of motions and peak angles) and GRF would increase as speed increased for all wearers. Method: Eleven experienced female wearers of moderate high-heel shoes (EW: age: 24.2±1.2 years; height: 160±2.2 cm; mass: 51.6±2.6 kg) and eleven matched controls (IEW; age: 23.7±1.3 years; height: 162.3±2.3 cm; mass: 52.6±4.5 kg) participated in this test with informed written consent, as approved by the Ethics Committee of Ningbo University. Subjects completed jogging and running tasks separately at self-selected speed along a 10-meter-walkway. A force platform (Kistler, Switzerland) was fixed in the middle of the walkway and utilized to collect GRF at the frequency of 1000 Hz. The 8-camera Vicon motion analysis system (Oxford Metrics Ltd., Oxford, UK) was used to capture lower limb kinematics at the frequency of 200 Hz. Subjects were required to wear tight-fitting pants and 16 reflective markers (diameter: 14 mm) were attached with adhesive on the left and right lower limbs, respectively. Result: Fig1, 2 summarize the main GRF and VALR characteristics of EW and IEW. Impact force (Fz1) showed no significant differences between wearing experience or speeds. The maximal vertical GRF (Fz2) of EW during jogging was significantly larger than that of IEW jogging. EW during running showed significantly larger Fz2 compared with IEW jogging and running. Discussion: A key finding of this study was that compared with IEW, EW showed reduced joint ROM during stance phase to prevent excessive joint loading except for motions of knee and hip in sagittal plane that respectively aid in propulsion and load attenuation instead. Moderate high-heel shoes placed IEW at a greater risk of joint and soft tissue injury with generally larger peak angles during stance phase. However, the effect of these conservative control strategies adopted by EW partially lost during running in comparison with jogging. As speed increased from jogging to running, EW mainly relied on increasing SL, leading to landing with narrow high heel, which consequently resulted in an extremely high loading rate. From a kinetic perspective, EW also tended to have bone-on-bone injury in high-heeled running. In conclusion, moderate high-heeled wearers who have to run, whether regularly or occasionally, are putting themselves at high risk of lower limb damage. If having to run on high heels, even moderate ones, it is crucial for wearers to control joint stability and strike pattern consciously. Reference Barkema, D. D., Derrick, T. R., & Martin, P. E. (2012). Heel height affects lower extremity frontal plane joint moments during walking. Gait & posture, 35(3), 483-488. Chien, H. L., Lu, T. W., & Liu, M. W. (2014). Effects of long-term wearing of high-heeled shoes on the control of the body``s center of mass motion in relation to the center of pressure during walking. Gait & posture, 39(4), 1045-1050. Dawson, J., Thorogood, M., Marks, S. A., Juszczak, E., Dodd, C., Lavis, G., & Fitzpatrick, R. (2002). The prevalence of foot problems in older women: a cause for concern. Journal of Public Health, 24(2), 77-84. Gu, Y., Li, F., Li, J., Feng, N., Lake, M. J., Li, Z., & Ren, J. (2014). Plantar Pressure Distribution Character In Young Female With Mild Hallux Valgus Wearing High-heeled Shoes. Journal of Mechanics in Medicine and Biology, 14(01), 1450008. Hong, W.-H., Lee, Y.-H., Chen, H.-C., Pei, Y.-C., & Wu, C.-Y. (2005). Influence of heel height and shoe insert on comfort perception and biomechanical performance of young female adults during walking. Foot & Ankle International, 26(12), 1042-1048.
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