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( Gi Tark Noh ),( Kyoung Ju Lee ),( Hee Jung Sohn ),( Kyung Han Lee ),( Won Seok Heo ),( Byung Sung Koh ),( Un Mi Han ),( Young A Bae ) 영남대학교 의과대학 2016 Yeungnam University Journal of Medicine Vol.33 No.1
Pulmonary epithelioid hemangioendothelioma (PEH) is a rare, low-to-intermediate malignant tumor of endothelial origin. Computed tomography (CT) findings of PEH demonstrate multiple small bilateral nodules; however, to the best of our knowledge, there were no reports on PEH coexisting with other malignancies. Here, we reported on a case involving PEH in a patient with colon cancer and breast cancer which was misconceived as pulmonary meta- stasis. A 63-year-old woman who suffered from constipation for 2 weeks visited our hospital. Colonoscopy showed a large mass with obstruction on hepatic flexure. The histological diagnosis was adenocarcinoma of the ascending colon. Multiple nodules in both lungs and breast were observed on a chest CT scan. A core biopsy of a breast nodule was performed and a diagnosis of invasive ductal carcinoma of the left breast was made. Pulmonary nodules observed on the chest CT scan was considered as pulmonary metastasis from colon or breast cancer. Laparoscopic right hemicolectomy was performed. At the same time, wedge resection of the lung was performed and pathological diagnosis was PEH. Radiologic features of PEH were difficult to distinguish from lung metastasis. Therefore the author reported a rare case involving PEH in a patient with primary malignancy of colon and breast.
Koh, Dong-Chan,Genereux, David P.,Koh, Gi-Won,Ko, Kyung-Seok Elsevier 2017 Chemical geology Vol.467 No.-
<P><B>Abstract</B></P> <P>Groundwater from pristine volcanic rock aquifers on dormant Jeju Island, Korea, was investigated to identify sources and geochemical processes of dissolved inorganic carbon (DIC) and related solutes along with characteristics of groundwater flow using a multi-isotope approach. δ<SUP>18</SUP>O, δ<SUP>2</SUP>H, and <SUP>3</SUP>H of groundwater indicated the water is of meteoric origin, and is mainly derived from recent recharge, except Na-rich mineral water which has a significant contribution of <SUP>3</SUP>H-free old water. <SUP>87</SUP>Sr/<SUP>86</SUP>Sr of dissolved Sr suggests that solutes in groundwater were mainly derived from old alkali basalt in the lower part of lava flows. δ<SUP>13</SUP>C<SUB>CO2(g)</SUB> calculated using δ<SUP>13</SUP>C<SUB>DIC</SUB> and measured hydrogeochemical parameters indicated that (1) biogenic soil CO<SUB>2</SUB> is a dominant source of DIC in low mineralized water, (2) CO<SUB>2</SUB>-rich water had mostly mantle-derived magmatic CO<SUB>2</SUB>, and (3) mineral water contained both biogenic and magmatic CO<SUB>2</SUB>. δ<SUP>13</SUP>C<SUB>CO2(g)</SUB> in mineral water was affected by precipitation of calcite, which complicated the estimation of the contribution of CO<SUB>2</SUB> sources to DIC. Concentrations of mobile elements were mainly controlled by the amount of magmatic CO<SUB>2</SUB> and groundwater residence time. δ<SUP>13</SUP>C<SUB>CO2(g)</SUB> and <SUP>3</SUP>H content were used to distinguish four types of groundwater with different spatial patterns of occurrence in relation to the volcanic stratigraphy of Jeju Island. Groundwater types I and II are low mineralized water with lower levels of DIC from biogenic CO<SUB>2</SUB>, composed of either recent recharge (<40years, type I) or older water with negligible <SUP>3</SUP>H (>60years, type II). Type III is Mg-rich mineral water with significant recent recharge while type IV is Na-rich mineral water with older residence time. Types III and IV had somewhat elevated levels of DIC (up to 7.6mM) with mixed signatures of magmatic and biogenic CO<SUB>2</SUB>, while CO<SUB>2</SUB>-rich water (a subset of type III) had DIC up to 100mM with signatures of mantle-derived magmatic CO<SUB>2</SUB>. Groundwater in the eastern area of Jeju Island is mostly type I, which can be attributed to a lack of both low-permeability rocks and recent volcanic rocks in that area. Types III and IV were found in the western area where the latest volcanic rocks are distributed. In the southwestern area, type III is associated with permeable basaltic aquifers with a contribution of magmatic CO<SUB>2</SUB> and type IV is from the younger lava flows dissected by older massive trachytic rocks and shallower hydrovolcanic tuffs, which led to the higher degree of mineralization. A conceptual model is proposed to integrate the chemical and isotopic constraints of groundwater with volcanic stratigraphy and suggest the processes that generated groundwater types with different residence times and chemical compositions. This study may contribute to understanding the processes of groundwater flow and mineralization in volcanic aquifers affected by deep-source CO<SUB>2</SUB> and variable residence time of groundwater in both dormant and active volcanic areas.</P>
Noh, Gi Tark,Lee, Kyoung Ju,Sohn, Hee Jung,Lee, Kyung Han,Heo, Won Seok,Koh, Byung Sung,Han, Un Mi,Bae, Young A Yeungnam University College of Medicine 2016 Yeungnam University Journal of Medicine Vol.33 No.1
Pulmonary epithelioid hemangioendothelioma (PEH) is a rare, low-to-intermediate malignant tumor of endothelial origin. Computed tomography (CT) findings of PEH demonstrate multiple small bilateral nodules; however, to the best of our knowledge, there were no reports on PEH coexisting with other malignancies. Here, we reported on a case involving PEH in a patient with colon cancer and breast cancer which was misconceived as pulmonary meta- stasis. A 63-year-old woman who suffered from constipation for 2 weeks visited our hospital. Colonoscopy showed a large mass with obstruction on hepatic flexure. The histological diagnosis was adenocarcinoma of the ascending colon. Multiple nodules in both lungs and breast were observed on a chest CT scan. A core biopsy of a breast nodule was performed and a diagnosis of invasive ductal carcinoma of the left breast was made. Pulmonary nodules observed on the chest CT scan was considered as pulmonary metastasis from colon or breast cancer. Laparoscopic right hemicolectomy was performed. At the same time, wedge resection of the lung was performed and pathological diagnosis was PEH. Radiologic features of PEH were difficult to distinguish from lung metastasis. Therefore the author reported a rare case involving PEH in a patient with primary malignancy of colon and breast.
( Hyun Gi Koh ),( Nam Kyu Kang ),( Eun Kyung Kim ),( William I. Suh ),( Won-kun Park ),( Bongsoo Lee ),( Yong Keun Chang ) 한국미생물생명공학회(구 한국산업미생물학회) 2019 Journal of microbiology and biotechnology Vol.29 No.6
Chlorella spp. are green algae that are found across wide-ranging habitats from deserts to arctic regions, with various strains having adapted to survive under diverse environmental conditions. In this study, two novel Chlorella strains (ABC-002, ABC-008) were isolated from a freshwater lake in South Korea during the winter season and examined for possible use in the biofuel production process. The comparison of ABC-002 and ABC-008 strains with Chlorella vulgaris UTEX265 under two different temperatures (10 ℃, 25 ℃) revealed their cold-tolerant phenotypes as well as high biomass yields. The maximum quantum yields of UTEX25, ABC- 002, and ABC-008 at 10 ℃ were 0.5594, 0.6747, and 0.7150, respectively, providing evidence of the relatively higher cold-resistance capabilities of these two strains. Furthermore, both the biomass yields and lipid content of the two novel strains were found to be higher than those of UTEX265; the overall lipid productivities of ABC-002 and ABC-008 were 1.7 ~ 2.8 fold and 1.6 ~ 4.2 fold higher compared to that of UTEX265, respectively. Thus, the high biomass and lipid productivity over a wide range of temperatures indicate that C. vulgaris ABC-002 and ABC-008 are promising candidates for applications in biofuel productions via outdoor biomass cultivation.