조기영어학습이 유아의 영어능력에 미치는 영향

김근영(Geunyoung Kim),김유리(Yoo Ree Kim),박혜경(Hyekyung Park),김가희(Gahee Kim) 한국산학기술학회 2016 한국산학기술학회논문지 Vol.17 No.11

조기 영어교육이 필요한 것인지, 그리고 효과가 있는 것인지에 대해서는 2000년대 이후 많은 연구들이 실시되어 왔으나, 상당수 연구들은 통제집단의 부재, 관련변인 통제의 실패, 혹은 간이검사의 사용 등으로 인해 해석의 어려움이 존재했다. 본 연구는 8개월간의 영어학습 프로그램이 유아의 영어능력에 유의미한 효과를 미치는 지를 알아보기 위해 미국에서 공식 언어검사로 가장 많이 사용되고 있는 WIDA검사를 사용하여 개입집단과 통제집단의 영어능력치를 3회에 걸쳐 측정하였다. 또 영어학습이 본격화 되기 이전의 아동의 한국어 능력, 지능, 성격변인, 그리고 부모의 사회경제적 변인 및 영어교육에 대한 태도를 측정하고 이를 통제하여 영어학습만의 고유효과를 알아보고자 하였다. 3차 검사를 완료한 39명의 유아들의 영어능력을 분석한 결과, 개입집단은 수용언어 발달과 표현언어 발달에 있어 관련변인의 효과를 통제한 후에도 여전히 통제집단 유아에 비해 우수하였다. 하지만 이러한 효과는 영어검사의 정답문항 수에 근거하였을 때에만 유의미하였으며, 집단간 질적인 측면에서 유의미한 변화는 발견되지 않았다. 본 연구의 결과는 단순 노출교육이라 하더라도 조기영어교육은 최소한 단기간 효과가 있음을 시사한다. Although a number of studies have been conducted in Korea since 2000 on the impact of early English education, their interpretation is still not conclusive, due to their lack of control groups and failure to control for third factors and use valid measurements. The present study was designed to examine the effect of an English education program on young children"s English proficiency after 8 months using the most well-known official English proficiency measure, the WIDA for kindergarteners. In addition, the children"s Korean language proficiency, cognitive abilities, personality, parents" SES, and parents" attitudinal variables before the education were measured and controlled. The results indicated that the intervention group performed better than the control group in both listening and speaking skills, even when all relevant factors were considered. This effect, however, was only found in the item-level analyses.

해수와 패각 기반 간접탄산화에서 설탕 및 구연산나트륨 첨가에 의한 탄산칼슘의 형태 및 입자크기 조절

김근영(GeunYoung Kim),김세훈(Sehun Kim),이유정(Youjeong Lee),김명진(Myoung-Jin Kim) 대한환경공학회 2020 대한환경공학회 학술발표논문집 Vol.2020 No.11

Attachment of flagellin enhances the immunostimulatory activity of a hemagglutinin-ferritin nano-cage

Lee, Emerson B.,Jeon, Hyung-Min,Kim, Chang-Ung,Park, Sang M.,Cho, Geunyoung,Kim, Hyun-Jin,Kim, Youngjin,Kim, Doo-Jin,Kim, Young S.,Lee, Hayyoung,Lee, Jie-Oh Elsevier 2019 Nanomedicine Vol.17 No.-

<P><B>Abstract</B></P> <P>Hemagglutinin (HA) displayed on a ferritin nano-cage has been shown to be effective in generating a potent immune response against a broad range of influenza infections. Here, we showed that conjugation of flagellin together with HA to the exterior surface of the ferritin cage greatly enhanced not only the humoral immune response in mice but also antigen-specific T cell responses that include Th1 cytokine secretion. The effect of flagellin remained essentially unchanged when the molar ratio of flagellin to HA was reduced from 1:1 to 1:3. Injection of the ferritin-HA-flagellin cage provided protection against lethal virus challenge in mice. We used a small immunoglobulin fragment V<SUB>L</SUB>12.3 as a convenient method for attaching HA and flagellin to the ferritin cage. This attachment method can be used for rapid screening of a variety of protein cages and nano-assemblies to identify the most suitable carrier and adjuvant proteins for the target antigen.</P> <P><B>Graphical Abstract</B></P> <P>We have shown that a small immunoglobulin fragment, V<SUB>L</SUB>12.3, as a convenient linker can be used for conjugating protein cages, antigens and adjuvants in this study. We showed that influenza hemagglutinin (HA) could be attached to ferritin and an artificial cage protein, I3-01, by this method. We also showed that Protective Antigen (PA) of <I>Bacillus anthracis</I> could be attached to the ferritin cage with high efficiency. We propose that this approach can be used to quickly screen a variety of protein cages and nano-assemblies to identify the best carrier and adjuvant proteins for desired antigens. To demonstrate the usefulness of our V<SUB>L</SUB>12.3 method in the vaccine development, we generated a ferritin-HA-flagellin nano-cage. We discovered that attachment of flagellin together with HA greatly enhanced not only total IgG level but also Th1 cytokine secretion and class switching to IgG2a in mice.</P> <P>[DISPLAY OMISSION]</P>

대설 대응의 제도적 개선을 위한 중요도 분석

Kim, Heejae,Yoon, Sanghoon,Park, Keunoh,Kim, Geunyoung 한국재난정보학회 2017 한국재난정보학회 논문집 Vol.13 No.3

본 연구는 대설재난 대응을 위한 제도적 개선요인을 도출하고 주요 우선순위를 선정하기 위해 AHP분석을 수행하였다. 그 결과, 대설대응관련 계획수립이 중요도 0.461로 가장 중요한 것으로 나타났다. 이는 대설대응체계 구축을 위해서는 시설, 자원, 정책보다 계획의 수립이 더 중요하다는 것을 의미한다. 대설대응을 위한 계획 중에서도 대응과 관련된 계획 수립이 종합중요도 0.175로 다른 개선요소에 비해 가장 우선적으로 선행되어야 한다고 도출되었다. 이것은 대설관련 계획 중 경감 및 예방, 대비, 대응, 복구계획 중에서 대응측면을 가장 중요하게 생각하는 것으로 대설과 관련된 법제도 개선시 가장 필요하다는 것을 시사해주고 있다. 본 연구결과는 향후 대선재난 대응을 위한 제도적 개선방안 수립시 기초자료로 활용할 수 있을 것이다. This study deducted institutional improvement factors for respond of heavy snowfall disaster and performed AHP analysis for choosing the priority. The result of Analysis, establishment of plan concerned heavy snowfall respond was represented most important factor(Importance : 0.461), this is meaningful establishment of plan is more important than facilities, sources, policies for building system of heavy snowfall respond. Establishment of plan concerned respond was represented most important element(Comprehensive Importance : 0.175) in plan for heavy snowfall respond, it is suggested that establishment of respond plan of heavy snowfall has to need for improving law and institution about heavy snowfall. The result of this study will be useful when the central or local government establish institutional improvement plan for respond of heavy snowfall disaster.

Simple Atmospheric-Pressure Nonthermal Plasma-Jet System for Poly(dimethylsiloxane) Bonding Process

Kim, Kangil,Kim, Geunyoung,Oh, Yeongtaek,Park, Tae-Gyu,Han, Dong Chul,Yang, Sang Sik IOP Publishing 2012 Japanese journal of applied physics Vol.51 No.6

도로 제설 시나리오별 소요 제설장비 및 차량 추정에 관한 연구

Kim, Heejae,Kim, Sunyoung,Kim, Geunyoung 한국재난정보학회 2017 한국재난정보학회 논문집 Vol.13 No.2

기후변화로 인한 지구 온난화 현상으로 대설재난의 발생을 예측하기가 더욱 어려워지면서 신속한 도로제설이 중요해지고 있다. 우리나라의 지자체는 관할 행정구역의 강설 및 도로특성을 고려하지 않고 과거 경험을 참고하여 제설장비와 차량을 보유하고 있다. 본 연구는 우리나라 지자체의 강설과 도로 특성을 고려하여 제설장비와 차량 수요를 추정하는 절차를 개발하는 데 목적이 있다. 본 연구는 첫 단계로 기상청의 과거 10년 강설자료를 이용하여 지역의 강설 특성을 유형화한 후 관리기관별 도로제설 연장을 산정하였다. 다음으로 도로제설 시나리오를 설정하여 지자체의 제설장비와 차량 수요를 추정하고 실제 보유량과 비교하였다. 마지막으로 지역별 강설량과 제설시간을 고려하여 지자체별 필요 제설장비와 차량수요를 추정하였다. 본 연구의 결과는 229개 지자체별로 적정 제설차량과 장비를 보유하고, 제설노선을 결정하는 대설재난 관리정책을 수립하는데 활용할 수 있다. Rapid roadway snow removal is significantly important due to difficult occurrence estimation of heavy snowfall disasters by global warming and climate change. Local governments of S. Korea have snow removal equipments and vehicles based on past experiences without considering snowfall and roadway characteristics. The objective of this research is to develop the demand estimation procedure for snow removal equipments and vehicles based on regional snowfall and roadway characteristics. This research first classifies regional snowfall characteristics using KMO's ten-year snowfall data. Second, roadway snow removal length is computed for local governments. Real possession data is compared with demand estimation of snow removal equipments & vehicles for each local government with roadway snow removal scenarios. Finally, required demands of snow removal equipments & vehicles are predicted by concerning regional snowfall amount and required snow removal hours. Results from this research are used for developing heavy snowfall disaster management policies for optimal demands and snow removal routes of 229 local governments.

The Study for Hazardous Material Incidents in Korea

Kim, Geunyoung,James E. Moore 한국방재학회 2009 한국방재학회논문집 Vol.9 No.1

Hazardous material (HazMat) is the material or substance that poses an unreasonable risk to human safety and health, and to property when transported in gases, solids, and liquids of all sizes. When HazMats are improperly released, they have potential to harm humans, property, or the environment to be considered hazardous, resulting in human-caused disasters. As the Korean economy has advanced, the use of HazMats has increased. And, the total number and the impacts of HazMat incidents have grown up. It increases the risk of HazMat incidents. When many goods of HazMats are transported from supply points to demand places, it is important to know what the types and characteristics of HazMat incidents are in terms of disaster management. The objectives of this research are: (1) to investigate types and characteristics of HazMats that generate HazMat incidents in Korea, and (2) to analyze time-series trends of HazMat incidents in terms of facilities and/or transportation. Statistical analysis methods including frequency analysis or analysis of category data are applied to examine the significance of difference in HazMat incidents.

Novel Fabrication Method of a Round Microtip Based on Aluminum Spike Phenomenon

Kim, Geunyoung,Kim, Kangil,Park, Tae-Gyu,Yang, Sang Sik IOP Publishing 2011 Japanese journal of applied physics Vol.50 No.r1

The Study for Spatial Change of Educational Conditions of Elementary Schools in Seoul

Kim GeunYoung 한국지역개발학회 2001 韓國地域開發學會誌 Vol.13 No.3

Application of antihelix antibodies in protein structure determination

Kim, Ji Won,Kim, Songwon,Lee, Haerim,Cho, Geunyoung,Kim, Sun Chang,Lee, Hayyoung,Jin, Mi Sun,Lee, Jie-Oh National Academy of Sciences 2019 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF Vol.116 No.36

<P><B>Significance</B></P><P>Antibodies have been found to be helpful for structural studies of challenging proteins by X-ray crystallography and electron microscopy. They are being used to construct useful protein nanostructures as well. Antibodies suitable for structural study should recognize the 3-dimensional conformations of target proteins. However, generating such antibodies and characterizing structures of their complexes with antigens take months or even years of research. Here, we show that we can expand the application of well-characterized antibodies by “transplanting” the alpha-helical epitopes that they recognize to proteins with completely different structures and sequences. Systematic screening of more antihelix antibodies will greatly expand the scope of the method.</P><P>Antibodies are indispensable tools in protein engineering and structural biology. Antibodies suitable for structural studies should recognize the 3-dimensional (3D) conformations of target proteins. Generating such antibodies and characterizing their complexes with antigens take a significant amount of time and effort. Here, we show that we can expand the application of well-characterized antibodies by “transplanting” the epitopes that they recognize to proteins with completely different structures and sequences. Previously, several antibodies have been shown to recognize the alpha-helical conformation of antigenic peptides. We demonstrate that these antibodies can be made to bind to a variety of unrelated “off-target” proteins by modifying amino acids in the preexisting alpha helices of such proteins. Using X-ray crystallography, we determined the structures of the engineered protein–antibody complexes. All of the antibodies bound to the epitope-transplanted proteins, forming accurately predictable structures. Furthermore, we showed that binding of these antihelix antibodies to the engineered target proteins can modulate their catalytic activities by trapping them in selected functional states. Our method is simple and efficient, and it will have applications in protein X-ray crystallography, electron microscopy, and nanotechnology.</P>