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- 저자 : Figueroa, Pablo (검색결과 51 건)
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Oscar Burbano‑Figueroa1,Jazmin Vanessa Pérez‑Pazos,Milena Moreno‑Moran 한국작물학회 2022 Journal of crop science and biotechnology Vol.25 No.3
Cassava · Commercial inoculants · Data envelopment analysis · DEA · Technical efciency · NPK · Yield gaps · Nutrient-limited yieldPlant growth promoting microorganisms (PGPMs) are inhabitants of the rhizosphere that are able to provide better growth and biomass accumulation. Current agronomic practices have depleted these communities, which has created the opportunity for the development of commercial inoculants. These products use strains that are able to interact with a wide range of plant species and survive in diverse environments. The use of these generalist strains is required for providing a widespread solution that aggregates enough demand to reach market scale. Growth promotion by generalist strains may be suboptimal in comparison to the efect provoked by native and host-specifc populations, but these specialist strains are not a marketavailable solution. In this work, we assess the nitrogen, phosphorus and potassium (NPK) use efciency provided by commercial inoculants to cassava plants using Data Envelopment Analysis (DEA) to demonstrate the advantages of conceiving nutrient-limited yield as a production function. We also estimate the prospective production frontier that commercial inoculants can provide to cassava plants. Our results suggest that commercial inoculants have potential for improving cassava yields via improved NPK use efciency. The methods presented here ofer an ecological/economic production framework for the assessment of PGPMs and PGPMs-based commercial inoculants that can be extended to other laboratory, greenhouse or feld situations. The simple, intuitive and graphical approximation that DEA ofers will facilitate the understanding of the concept of technical efciency and the role of commercial inoculants on closing yield gaps
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Figueroa-Céspedes Ignacio(Figueroa-Céspedes Ignacio),Guerra Paula(Guerra Paula) The Pacific Early Childhood Education Research Ass 2024 Asia-Pacific journal of research in early childhoo Vol.18 No.1
This article analyses the experience of a Chilean early childhood (EC) teacher in the context of the COVID-19 pandemic. Part of a broader qualitative and narrative research, this article is a case study based on her professional experience during the pandemic. The results reveal four phases in the process: (1) initial confusion, (2) proposal, (3) disappointment and action, (4) balance and dialogue. The narrative shows a series of situations experienced by the EC teacher in her relationship with the children’s families, where identity negotiation emerged linked to the revalidation of her professional role. In addition, developing teaching and collaborative skills to respond to emergency situations is highlighted. Based on this experience, the need to elicit cultural changes that articulate care and pedagogical fields in EC education in Chile is analysed.
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L. Figueroa-Valverde,F. Dı´az-Cedillo,E. Garcı´a-Cervera,E. Pool Go´mez,M. Lo´pez-Ramos,M. Rosas-Nexticapa,R. Martinez-Camacho 대한약학회 2013 Archives of Pharmacal Research Vol.36 No.10
Experimental studies indicate that some steroidderivatives have inotropic activity; nevertheless, there isscarce information about the effects of the dehydroisoandrosteroneand its derivatives at cardiovascular level. Inaddition, to date the cellular site and mechanism of actionof dehydroisoandrosterone at cardiovascular level is veryconfusing. In order, to clarify those phenomena in this study,a dehydroisoandrosterone derivative was synthesized withthe objective of to evaluate its activity on perfusion pressureand coronary resistance and compare this phenomenon withthe effect exerted by dehydroisoandrosterone. The Langendorfftechnique was used to measure changes on perfusionpressure and coronary resistance in an isolated rat heartmodel in absence or presence of dehydroisoandrosterone andits derivative. Additionally, to characterize the molecularmechanism involved in the inotropic activity induced bydehydroisoandrosterone derivative was evaluated by measuringleft ventricular pressure in absence or presence offollowing compounds; flutamide, prazosin, metoprolol andnifedipine. The results showed that dehydroisoandrosteronederivative significantly increased the perfusion pressure andcoronary resistance in comparison with the control conditionsand dehydroisoandrosterone. Additionally, other dataindicate that dehydroisoandrosterone derivative increase leftventricular pressure in a dose-dependent manner [1 9 10-9–1 9 10-4 mmol]; nevertheless, this phenomenon was significantlyinhibited by nifedipine at a dose of 1 9 10-6mmol. In conclusion, these data suggest that dehydroisoandrosteronederivative induces positive inotropic activitythrough of activation the L-type calcium channel.
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Whole-body vibration as a potential countermeasure for dynapenia and arterial stiffness
Arturo Figueroa,Salvador J. Jaime,Stacey Alvarez-Alvarado 한국한의학연구원 2016 Integrative Medicine Research Vol.5 No.3
Age-related decreases in muscle mass and strength are associated with decreased mobility, quality of life, and increased cardiovascular risk. Coupled with the prevalence of obesity, the risk of death becomes substantially greater. Resistance training (RT) has a well-documented beneficial impact on muscle mass and strength in young and older adults, although the high-intensity needed to elicit these adaptations may have a detrimental or negligible impact on vascular function, specifically on arterial stiffness. Increased arterial stiffness is associated with systolic hypertension, left ventricular hypertrophy, and myocardial ischemia. Therefore, improvements of muscle strength and arterial function are important in older adults. Recently, whole-body vibration (WBV) exercise, a novel modality of strength training, has shown to exhibit similar results on muscle strength as RT in a wide-variety of populations, with the greatest impact in elderly individuals with limited muscle function. Additionally, WBV training has been shown to have beneficial effects on vascular function by reducing arterial stiffness. This article reviews relevant publications reporting the effects of WBV on muscle strength and/or arterial stiffness. Findings from current studies suggest the use of WBV training as an alternative modality to traditional RT to countermeasure the age-related detriments in muscle strength and arterial stiffness in older adults.
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Accumulation of High Levels of ABA Regulates the Pleiotropic Response of the nhr1 Arabidopsis Mutant
Francisco Quiroz-Figueroa,Adrián Rodríguez-Acosta,Amed Salazar-Blas,Elizabeta Hernández-Domínguez,Maria Eugenia Campos,Nobutaka Kitahata,Tadao Asami,Rosa M. Galaz-Avalos,Gladys I. Cassab 한국식물학회 2010 Journal of Plant Biology Vol.53 No.1
Plants have evolved a variety of mechanisms for responding to environmental cues, which allows them to survive in the presence of limited resources or environmental stresses. One of the most significant growth adaptations plants have attained is tropism, a growth response that involves bending of plant organs toward or away from a stimulus. Roots exhibit hydrotropism in response to moisture gradients, which is thought to be critical in acquiring water and establishing their stand in the soil. However, the mechanism underlying hydrotropism remains unsolved. Here, we report that the no hydrotropic response (nhr1) mutant of Arabidopsis, which is impaired in hydrotropism, is tolerant to drought. The no hydrotropic response phenotype of nhr1 was repressed by AbamineSG,an inhibitor of abscisic acid (ABA) biosynthesis, indicating that ABA negatively regulates hydrotropism. Furthermore,the content of ABA was higher in nhr1 compared to those of wild type (wt). However, the higher ABA levels in nhr1plants were not due to higher transcript levels of 9-cisepoxycarotenoid dioxygenase (NCED3), since these were diminished compared to those of wt. Our results indicated that the root hydrotropic response of the nhr1 mutant is modulated by ABA and that the higher ABA levels of the mutant might confer it drought resistance.
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Diana Gabriela Figueroa-Pina,Jorge Luis Chavez-Servin,Karina de la Torre-Carbot,Maria del Carmen Caamano-Perez,Gabriela Lucas-Deecke,Patricia Roitman-Genoud,Laura Regina Ojeda-Navarro 한국영양학회 2021 Nutrition Research and Practice Vol.15 No.2
BACKGROUND/OBJECTIVES: Increasing the consumption of vegetables and fruits in Mexico remains a challenge. Promoting sustainable food production systems through schools may be an effective way to educate young people about food and nutrition issues. A study of nutritional education in adolescents, based on the school garden, is necessary in order to evaluate its effects on the consumption of fruits and vegetables among middle- and upper-income segments of the population. The objective of this study was to evaluate the effect of an educational intervention, accompanied by a school garden as an educational teaching tool, to improve vegetable and fruit consumption by Mexican teenagers attending a private middle/high school. SUBJECTS/METHODS: Teenagers between 12 and 18 years of age (n = 126) attending a private middle/high school in Queretaro, Mexico participated in a 3-arm, controlled, comparative impact study using a vegetable and fruit consumption frequency questionnaire, food consumption diaries, a psychosocial factor assessment questionnaire of vegetable and fruit consumption, and structured interviews. The participants were randomized into 3 experimental groups: 1) food education + school garden (FE + SG), 2) FE only, and 3) control group (CG). RESULTS: The FE + SG and FE groups significantly increased the frequency and daily intake of vegetables and fruits compared to the CG. The FE + SG group showed greater understanding of, reflection upon, and analysis of the information they received about vegetable and fruit consumption, as well as a greater willingness to include these in their daily diet. CONCLUSIONS: FE accompanied by a SG as a teaching tool is more effective at promoting vegetable and fruit consumption than either education alone or control in teenagers in middle-upper income segments of the population.
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Hasan Brau-Figueroa,Eder Arango-Bravo,Denisse Castro-Eguiluz,Tatiana Galicia-Carmona,Leopoldo Abraham Lugo-Alferez,Ivette Cruz-Bautista,Roberto Jiménez-Lima,Lucely Cetina-Pérez 대한암학회 2022 Cancer Research and Treatment Vol.54 No.2
Purpose The standard treatment for locally advanced cervical cancer (LACC) is concomitant chemoradiotherapy with cisplatin (CDDP) followed by brachytherapy. The presence of comorbidities are risk factors for nephrotoxicity and are associated with lower survival. Gemcitabine is a radiosensitizing drug that has shown efficacy and safety in this context. The effectiveness of concomitant chemoradiotherapy with gemcitabine was evaluated versus cisplatin in LACC patients with comorbidities and preserved renal function. Materials and Methods An observational, longitudinal and paired study was carried out that included patients treated between February 2003 and December 2015. The primary objectives were to evaluate response rates, progression-free survival, and overall survival; the secondary objectives were to evaluate toxicity and renal function. Results Sixty-three patients treated with gemcitabine at 300 mg/m2 weekly and 126 patients treated with CDDP 40 mg/m2 weekly were included. There were no significant differences in response rates and survival rates. Treatment with cisplatin presented a higher frequency of hematological toxicities, while gemcitabine presented a higher frequency of gastrointestinal toxicities. A decrease in glomerular filtration rate (GFR; baseline vs. 1-year post-treatment) was observed in the cisplatin group (p=0.002), while not in the gemcitabine group (p=0.667). In a multivariate analysis, it is observed that only CDDP correlates with the decrease in GFR (hazard ratio, 2.42; p=0.012). Conclusion In LACC patients with comorbidities, gemcitabine and CDDP show the same efficacy, with different toxicity profiles. Treatment with cisplatin is associated with a significant decrease in GFR during follow-up, compared to treatment with gemcitabine that does not decrease it. PurposeThe standard treatment for locally advanced cervical cancer (LACC) is concomitant chemoradiotherapy with cisplatin (CDDP) followed by brachytherapy. The presence of comorbidities are risk factors for nephrotoxicity and are associated with lower survival. Gemcitabine is a radiosensitizing drug that has shown efficacy and safety in this context. The effectiveness of concomitant chemoradiotherapy with gemcitabine was evaluated versus cisplatin in LACC patients with comorbidities and preserved renal function. Materials and MethodsAn observational, longitudinal and paired study was carried out that included patients treated between February 2003 and December 2015. The primary objectives were to evaluate response rates, progression-free survival, and overall survival; the secondary objectives were to evaluate toxicity and renal function. ResultsSixty-three patients treated with gemcitabine at 300 mg/m2 weekly and 126 patients treated with CDDP 40 mg/m2 weekly were included. There were no significant differences in response rates and survival rates. Treatment with cisplatin presented a higher frequency of hematological toxicities, while gemcitabine presented a higher frequency of gastrointestinal toxicities. A decrease in glomerular filtration rate (GFR; baseline vs. 1-year post-treatment) was observed in the cisplatin group (p=0.002), while not in the gemcitabine group (p=0.667). In a multivariate analysis, it is observed that only CDDP correlates with the decrease in GFR (hazard ratio, 2.42; p=0.012).ConclusionIn LACC patients with comorbidities, gemcitabine and CDDP show the same efficacy, with different toxicity profiles. Treatment with cisplatin is associated with a significant decrease in GFR during follow-up, compared to treatment with gemcitabine that does not decrease it.
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