Structural and mechanical investigations of magnesium and fluoride doped nanosize calcium phosphates

Zafer Evis 한양대학교 세라믹연구소 2010 Journal of Ceramic Processing Research Vol.11 No.6

Thoracic metastasis in advanced ovarian cancer: comparison between computed tomography and video-assisted thoracic surgery

Oleg Mironov,Evis Sala,Svetlana Mironov,Harpreet Pannu,Dennis S. Chi,Hedvig Hricak 대한부인종양학회 2011 Journal of Gynecologic Oncology Vol.22 No.4

Objective: To determine which computed tomography (CT) imaging features predict pleural malignancy in patients with advanced epithelial ovarian carcinoma (EOC) using video-assisted thoracic surgery (VATS), pathology, and cytology findings as the reference standard. Methods: This retrospective study included 44 patients with International Federation of Obstetrics and Gynecology (FIGO) stage III or IV primary or recurrent EOC who had chest CT ≤30 days before VATS. Two radiologists independently reviewed the CT studies and recorded the presence and size of pleural effusions and of ascites; pleural nodules, thickening, enhancement, subdiaphragmatic tumour deposits and supradiaphragmatic, mediastinal, hilar, and retroperitoneal adenopathy; and peritoneal seeding. VATS, pathology, and cytology findings constituted the reference standard. Results: In 26/44 (59%) patients, pleural biopsies were malignant. Only the size of left-sided pleural effusion (reader 1: rho= -0.39, p=0.01; reader 2: rho=-0.37, p=0.01) and presence of ascites (reader 1: rho=-0.33, p=0.03; reader 2: rho=-0.35, p=0.03) were significantly associated with solid pleural metastasis. Pleural fluid cytology was malignant in 26/35 (74%) patients. Only the presence (p=0.03 for both readers) and size (reader 1: rho=0.34, p=0.04; reader 2: rho=0.33, p=0.06) of right-sided pleural effusion were associated with malignant pleural effusion. Interobserver agreement was substantial (kappa=0.78) for effusion size and moderate (kappa=0.46) for presence of solid pleural disease. No other CT features were associated with malignancy at biopsy or cytology. Conclusion: In patients with advanced EOC, ascites and left-sided pleural effusion size were associated with solid pleural metastasis, while the presence and size of right-sided effusion were associated with malignant pleural effusion. No other CT features evaluated were associated with pleural malignancy. Objective: To determine which computed tomography (CT) imaging features predict pleural malignancy in patients with advanced epithelial ovarian carcinoma (EOC) using video-assisted thoracic surgery (VATS), pathology, and cytology findings as the reference standard. Methods: This retrospective study included 44 patients with International Federation of Obstetrics and Gynecology (FIGO) stage III or IV primary or recurrent EOC who had chest CT ≤30 days before VATS. Two radiologists independently reviewed the CT studies and recorded the presence and size of pleural effusions and of ascites; pleural nodules, thickening, enhancement, subdiaphragmatic tumour deposits and supradiaphragmatic, mediastinal, hilar, and retroperitoneal adenopathy; and peritoneal seeding. VATS, pathology, and cytology findings constituted the reference standard. Results: In 26/44 (59%) patients, pleural biopsies were malignant. Only the size of left-sided pleural effusion (reader 1: rho= -0.39, p=0.01; reader 2: rho=-0.37, p=0.01) and presence of ascites (reader 1: rho=-0.33, p=0.03; reader 2: rho=-0.35, p=0.03) were significantly associated with solid pleural metastasis. Pleural fluid cytology was malignant in 26/35 (74%) patients. Only the presence (p=0.03 for both readers) and size (reader 1: rho=0.34, p=0.04; reader 2: rho=0.33, p=0.06) of right-sided pleural effusion were associated with malignant pleural effusion. Interobserver agreement was substantial (kappa=0.78) for effusion size and moderate (kappa=0.46) for presence of solid pleural disease. No other CT features were associated with malignancy at biopsy or cytology. Conclusion: In patients with advanced EOC, ascites and left-sided pleural effusion size were associated with solid pleural metastasis, while the presence and size of right-sided effusion were associated with malignant pleural effusion. No other CT features evaluated were associated with pleural malignancy.

Structural and mechanical characteristics of hydroxyapatite and tri-calcium phosphates doped with Al3+ and F- ions

A. Tahmasebifar,Z. Evis 한양대학교 세라믹연구소 2013 Journal of Ceramic Processing Research Vol.14 No.4

In this study, doping of aluminum (Al3+) and/or fluoride (F) ions into tri-calcium phosphate (TCP)-hydroxyapatite (HA) composites at various compositions were performed to investigate their microstructure and mechanical properties. Composites were synthesized by a precipitation method and sintered at 1100 o C for 1 hr and 5 hrs. Densities of the sintered materials were increased by extending the sintering time and increasing the amount of Al3+ and F doping. β-TCP was observed as the main phase in the composites by Rietveld refinement method. Moreover, considerable amount of HA was detected in the composites. Lattice parameters decreased upon ions substitution. Addition of doping ions resulted in smaller grains. In general, presence of Al3+ ions in the composites had negative effects on mechanical properties of the samples while substitution of the F ions improved that of the samples.

Synthesis of baghdadite using modified sol–gel route and investigation of its properties for bone treatment applications

Jodati Hossein,Tezcaner Ayşen,Evis Zafer,Alshemary Ammar Z,Çelik Erdal 한국세라믹학회 2023 한국세라믹학회지 Vol.60 No.2

The requirement for biomaterials with superior properties, used in bone treatment applications, is inevitable due to escalated bone tissue defects. Baghdadite (BAG) is a calcium silicate that benefits from the presence of zirconium (Zr) in its structure and has attracted huge attention in recent years. In this study, a modified sol–gel route was proposed to synthesize BAG by dissolving Zr precursor separately and using optimum amounts of solvent and chelating agent. Due to thermal gravimetric analysis and differential thermal analysis (TGA–DTA), X-ray diffraction (XRD), and Fourier Transform Infrared Spectroscopy (FTIR) results, the BAG nanoparticles were successfully synthesized using this modified approach for the first time, and they were comprehensively characterized in terms of physicochemical, mechanical, and biological properties. During synthesis, a transparent sol without any insoluble Ca or Zr precursors and/or no premature gelation was observed, unlike samples that we produced using the conventional sol–gel method in the literature. The crystalline BAG nanoparticles with semi-spherical shapes demonstrated ~ 20% weight loss after 28 days during the biodegradability test, extensive bioactivity, and enhanced mechanical strength (~4 MPa). Moreover, BAG powder was biocompatible with no cytotoxic effect and osteoinductive in the absence of an osteogenic medium. We believe that the synthesized BAG nanoparticles through this modified sol–gel route could serve as a promising biomaterial for cancellous bone defect treatment applications.

Clinical, Quality of Life, Patient Adherence, and Safety Outcomes of Short-Course (12 Weeks) Treatment with Cyclosporine in Patients with Severe Psoriasis (the Practice Study)

( Sandra Swimberghe ),( Pierre Dominique Ghislain ),( Evis Daci ),( Katrien Allewaert ),( Kris Denhaerynck ),( Christine Hermans ),( Christy Pacheco ),( Stefaan Vancayzeele ),( Karen Macdonald ),( Ivo 대한피부과학회 2013 Annals of Dermatology Vol.25 No.1

Background: Apart from clinical outcomes, the realworld outcomes of intermittent short-course cyclosporine treatment remain poorly documented. Objective: To evaluate various outcomes of short-course cyclosporine treatment for severe psoriasis; and to describe dermatologists` use of the Rule of Tens. Methods: A 12-week pharmacoepidemiological study; 112 evaluable patients recruited by 43 dermatologists. Results: The mean initial cyclosporine dose was 2.88±0.74 mg/kg/day. At 12 weeks, 64.3% of patients were continued beyond the study period at mean dose of 2.51±0.91 mg/kg/day. Percent body surface affected, Psoriasis Area Severity Index score, and patient and physician rating of psoriasis severity decreased significantly, while quality of life (QoL) improved significantly. Median patient satisfaction at 12 weeks was 85 (0∼100 scale). Patient-reported non-adherence was 43.9% and 56.1%, respectively at both the time points (p=0.18). In modeling on logarithmized outcomes variables, living along was consistently the single most important (negative) determinant of therapeutic and patient outcomes. Safety and tolerance parameters were similar to the ones reported in the literature. Only 7.3% of physicians correctly identified the measures included in the Rule of Tens and the Rule`s criterion for inferring severe psoriasis. Conclusion: With adequate monitoring and patient adherence, cyclosporine treatment reduces the severity of severe psoriasis, improves QoL, and is appropriately tolerated; leading to high patient satisfaction. Social support is a key determinant of therapeutic and patient outcomes and patients living along may require clinical attention. The relevance of the Rule of Tens was not evident. (Ann Dermatol 25(1) 28∼35, 2013)

유고슬라비아(세르비아) 전통 구비문학

Nada Milo?evi?-?orđevi? 한국외국어대학교(글로벌캠퍼스) 동유럽발칸연구소 2003 동유럽발칸연구 Vol.11 No.2

본 논문은 주로 부크 스테파노비치 까라지치(Vuk Stefanovi Karad i )에 의해 집성된 구비서정시와 구비서사시, 그리고 또 다른 갈래들에 대한 최초의 체계적인 채록집이 출판된 15세기로부터 19세기에 이르는 시기의 구비전승에 대한 개괄을 기술한다.구비서정시는 가부장적 문화의 요소가 살아 있는, 매우 오래된 시대적 관점의 숨겨진 층위를 가진 복합적인 구비전승양식으로 간주된다. 구비서정시가 개인적인 감정과 소망을 표현한다고 생각됨에도 불구하고, 단도직입적인 감정의 표현은 거의 드문 편이다. 이에 대한 설명은 문화와 집단적 표현간의 상호의존에서 찾아질 수 있다. 얼마간의 극단적으로 섬세한 시가들은 여성들에게 강요된 모든 억압들을 드러내기도 하며, 따라서 시가들은 가장 적합한 외적 심상을 선택해야만 하고, 고도로 발달된 詩作法의 실재를 통해서 감정의 메시지를 구체화해야만 한다. 동시에, 심리학적으로 중요한 기능을 가진 가공하지 않은 행위예술을 참고해야만 한다.코소보에 관한 구비서사시가 모든 개개인이 자신의 국가에 속한다는 사실과 국가를 향한 기사로서의 의무를 깨닫게 되었을 때 나타났다는 것은 본 논문에서 지적되었다. 밀로슈 오빌리치(Milo Obili )에 의한 터키의 술탄 무라드(Murad)의 죽음은 역사적인 행위로써 애국적인 것이었으며, 이는 자신의 국가를 위해서 자신을 희생한다는 밀로슈의 내적 필요에 의해 유발된 것이었다. 이는 부크 브랑코비치(Vuk Brankovi )의 비방과 자신으로부터 그것을 떨쳐버리려는 밀로슈의 욕구 사이에서 起因效果를 지닌 기사도적 구비서사시의 모티프방식에 적합한 것이며, 따라서 군주인 라자르(Lazar)에 대한 자신의 충성심을 증명하는 것은 시적 내용에 있어서 초기 구비서사시의 자극이 되었고, 전쟁의 비극적 결말을 제공하는 비방자가 배신자로 되었다는 사실에 의해 확대된 것이다.모든 시가는 개인적 감정과 영웅 서사시의 상호관계에 양식을 맞추고, 따라서 객관적인 역사 사건들은 모든 인물의 개인적 운명과 동일시된다.반란에 대한 시가들 속에서 농민이라는 인물들은 자신들을 코소보에서 희생당한 귀족의 직접적인 자손으로 생각한다. 코소보 서사시와의 근접성은 문체적 표현접근에 의해 지속적으로 이루어진다.매우 풍부한 구비산문 역시 언급되어져야만 한다. 그것은 두 개의 기본적인 범주로 나뉘어진다: 설화부분과 전설부분. 구비산문의 기본적인 특징은 문화적 특색을 보여주는, 갈래의 국제적인 체계에 맞춰져 있다.

The Lack of Sex Differentiation in Micronuclei Frequency in Umbilical Cord Blood Lymphocytes

Olivera Milo?evi?-Djordjevi?,Darko Gruji?i?,Dargoslav Marinkovi? 한국유전학회 2007 Genes & Genomics Vol.29 No.1

The baseline frequency of DNA changes is influenced by many exogenous and endogenous factors, such as age, sex and environmental toxicants. The purpose of this study was to uclei in umbilical blood lymphocytes of neonates immediately after birth. Umbilical cord blood samples were obtained from a total of 52 newborns (26 females and 26 males). Isolated lymphocytes from all subjects were cultured by using the whole blod method, and were blocked with cytochalasin B. One lished criteria. The obtained mean values of baseline micronuclei in umbilical lymphocytes were 5.31± 3.17 for females and 4.77± 2.82 for males (t = 0.592, p = 0.559). The analysis of variance did not reveal any statisticaly significant diference in a comparison of betwen-groups vs within-group variance with one micronucleus were more prevalent (0.49% for females and 0.45% for males), while cels with two micronuclei were observed less. Three female babies out of 26 (1.54%) and only two male babies out of 26 (7.69%) showed two micronuclei per binucleated cel. Our resu l t s d i d n o t s h o w a n y significant efect of sex on micronuclei frequency in umbilicalnewborns.

Cultural Diversity in Greek Religion: From the Modern Anastenaria Festival to the Ancient World

( Evy Johanne Haland ) 부산외국어대학교 지중해연구소 2013 The Mediterranean Review Vol.6 No.1

The Anastenaria festival is celebrated in the village of Agia Elene in Greek Macedonia in May. The main ritual during the festival is the ecstatic dance over red-hot coals by people who are possessed by their saint. Thus, the festival presents a ritual, which in many ways is in opposition to the official Orthodox religion. A particular theme in the festival, which has been compared with ancient sources, is the "Dionysian" element and the "holy dyade" related to the cult of the Great Mother and the personified Bull god, via several couples, such as Kybele and Attis, and the modern cult dedicated to Agia , i.e. Saint Elene and Agios , Saint K?nstantinos. But, the similarities between the ancient cult dedicated to Aphrodite and Adonis and the modern cult may also be of relevance. Accordingly, the article will present the modern Anastenaria festival. It will further make a comparison with an ancient parallel celebrated in connection with the same passage during the agricultural year, the unofficial Athenian festival dedicated to the vegetation god, Adonis, the Adonia. A reason to this is that both festivals present ritual diversity within their respective societies, simultaneously as they belong to the same cosmologies within their respective communities.

Greek Women, Power and the Body : From Fieldwork on Cults Connected with the Female Sphere towards a Deconstruction of Male Ideologies, Modern and Ancient

Evy Johanne H?land 부산외국어대학교 지중해연구소 2010 The Mediterranean Review Vol.3 No.1

Based on studies in ancient Greek sources, mainly produced by men, combined with results from fieldwork carried out on contemporary Greek religious festivals, a comparison is made with similar ancient festivals though an analysis of the fertility-cult, which is important in the festivals. This is a useful way to try to consider the female part of society, since women are the central performers of the actual cult that plays an important role within the official male value-system. This is the value-system, from which the festivals and the society that they reflect, traditionally have been considered. The absence of the female value-system leaves previous analyses one-sided and incomplete. Therefore, a comprehensive analysis requires the female point of view to be included. Hence, the paper argues for the importance of changing our approach when working with ancient culture. Taking account of the female sphere, which still exists in Greece, provides us with a basis for considering the female part of society. But, by so doing, the official male perspective, which is similar to the Western male perspective generally applied within Greek studies, has to be deconstructed. So, by arguing for the importance of not using the general male model when presenting Greek women, the article tries to deconstruct the male ideologies “from within”.

Multi-objective Mathematical Modeling for Scheduling Machines in Parallel with Batch Processors

Evy Segarawati Ampry,Aan Komariah,Dedy Achmad Kurniady,Muhammad Rafiq,Asep Priatna,Muneam Hussein Ali,Haydar Abdulameer Marhoon,Lakshmi Thangavelu,Purnima Chaudhary 대한산업공학회 2022 Industrial Engineeering & Management Systems Vol.21 No.2

In this paper, the problem of scheduling the production of unrelated parallel machines to simultaneously minimize the goals of production time span, early and late fines, and the cost of purchasing machines is investigated, and a two-objective mathematical model is considered considering clearance and preparation times and limit capacity. Due to faster and cheaper operations with batch processors and increasing the efficiency of operating systems, all machines are batch processors. Initially, the model is coded and executed using the exact method in GAMS software. Due to the hard-NP nature and complex nature of the problem, a multi-objective meta-heuristic algorithm based on the coordination search method is proposed and designed. Then Taguchi method is used to find the best level for the algorithm parameters, and two examples of problems in different dimensions of tasks and machines are presented and solved by this proposed algorithm. The results of the calculations show the efficiency of this algorithm to generate more solutions at a much lower solution time.