조영제 사용 전 후 확산강조영상 검사의 비교 분석에 대한 연구

구은회,Goo, Eun-Hoe 대한디지털의료영상학회 2009 대한디지털의료영상학회논문지 Vol.11 No.2

The purpose of this study would evaluate if having clinical effects on diffusion image with quantitative analysis through ADC values of brain's normal tissue and lesions before and after contrast injections using a 3.0T. From November in 2007 until December in 2008, a total of 32 patient was performed on 3.0T(Signa Excite, GE Medical System, USA) with the normal or lesions in the patient who requests diffusion weighted image with 8channel head coil. The pulse sequence was used with spin echo EPI(TR: 10000msec, TE: 72.2 msec, Matrix: 128*128, FOV: 240 mm, NEX: 1, diffusion direction: 3, b-value: 1000). Measurement results of ADC values on lesions, CSF, white matter, gray matter, lesions after contrast injection were measured less 75% than before contrast injection, infarction: 100%, CSF: 78%(high), white matter: 71.4%(low), gray matter: 50%(high, low). The results of paired t-test on the deference of ADC values which statically is significant in three(lesions, CSF, white matter)regions except for white matter(p<0.05). Quantitative analysis of lesions, CSF, white matter, gray matter have difference on all regions. ADC values were low in lesions and white matter, normal CSF after contrast injection commonly is high than before contrast injection, ADC values which white matter were high and low (50:50) after contrast injection. 3.0T diffusion weighted image clinically supposed that performing DWI examination after contrast injection was not desirable because of having effects on brain tissue.

Auditory language task를 이용한 자기공명영상에 관한 고찰 : Visual language task와의 비교

구은회,김인수,정헌정,유병기,김동성,최천규,송인찬,Goo Eun Hoe,Kim In Soo,Jeong Heon Jeong,You Byung Ki,Kim Dong Sung,Choi Cheon Kyu,Song In Chan 대한방사선사협회 2002 대한방사선사협회지 Vol.28 No.1

Purpose: To make a comparison evaluated of the auditory instrument and visual instrument language generation task in the fMRI, on the adult volunteers. Materials and Methods: Total of 6 normal adult volunteers(men;4, women;2, mean age;24) performed in 1.5

관류자기공명영상의 이해

구은회,Goo, Eun-Hoe 대한디지털의료영상학회 2013 대한디지털의료영상학회논문지 Vol.15 No.1

Perfusion MR imaging is how to use exogenous and endogenous contrast agent. Exogenous perfusion MRI methods which are dynamic susceptibility contrast using $T2^*$ effect and dynamic contrast-enhanced using T1 weighted image after injection contrast media. An endogenous perfusion MRI method which is arterial spin labeling using arterial blood flow in body. In order to exam perfusion MRI in human, technical access are very important according to disease conditions. For instance, dynamic susceptibility contrast is used in patients with acute stroke because of short exam time, while dynamic susceptibility contrast or dynamic contrast enhancement provides the various perfusion information for patients with tumor, vascular stenosis. Arterial spin labeling is useful for children, women who are expected to be pregnant. In this regard, perfusion MR imaging is required to understanding, and the author would like to share information with clinical users

간 전이환자에서 최적의 펄스시퀀스에 따른 SPIO 특이성 조영제의 국소병변검출: Case review

구은회,Goo, Eun-Hoe 대한디지털의료영상학회 2012 대한디지털의료영상학회논문지 Vol.14 No.2

To compare the accuracy of breath-hold magnetic resonance imaging sequences to establish the most effective superparamagnetic iron oxide-enhanced sequence for detection of hepatic metastases. A total of 100 patients(50men and 50women, mean age: 60years) with liver disease(including malignant and benign liver lesions) were investigated at 3.0T machine (GE, General Electric Medical System, Excite HD) with 8Ch body coil. Pulse sequence for MR imaging decided to the FS-T2-FSE-RT(TR/TE/Thick./Freq./Phase=12857ms/100ms/7mm/512/384), MGRE(TR/TE/Thick./Freq./Phase=100ms/9.7ms/7mm/384/288), in-out of phase echo(TR/$TE_1$, $TE_2$/Thick./Freq./Phase=140ms/2.4, 5.8ms/7mm/352/300), Images obtained before the injection of SPIO. Six sequences were optimized for lesion detection: FS-T2-FSE-RT, multigradient recalled echo data image(MGRE), T2-weighted MGRE with an 9.7msec echo time. Images were reviewed independently by five blinded observers. The accuracy of each sequence was measured by using picture archiving communication system analysis. All results were correlated with findings at multidectator computed tomography examination. Differences between the mean results of the six observers were measured by using paired student t-test analysis. Postcontrast T2-weighted MGRE sequences were the most accurate and were significantly superior to postcontrast FS-T2-FSE-RT, T2-weighted MGRE, in-out of phase MR sequences(p < .05). For all lesions that were malignant or smaller than 1 cm, respectively, contrast to noise ratio of pre and postcontrast sequences were -1and -0.3 for T2-weighted FSE, 0.53 and 4.5 in-out of phase, 7, 7.08, 5.08, 3.32, 1.7, 1.16, 0.79, 0.68 for GRE with 2.9, 7.5, 12.1, 16.6, 21.2, 25.8, 30.4, 35.0 TE values. Breath-hold various TE precontrast sequences offer improvement in sensitivity compared with fixed multigradient recalled echo sequences alone.

고 자장에서 Dynamic Susceptibility Contrast 효과에 관한 연구 : Gradient EPI와 Spin-EPI기법의 비교

구은회,채홍인,박종배,임청환,김정구,Goo, Eun-Hoe,Chae, Hong-In,Park, Jong-Bae,Im, Cheong-Hwan,Kim, Jeong-Koo 대한디지털의료영상학회 2007 대한디지털의료영상학회논문지 Vol.9 No.2

We have evaluated and compared of gradient echo and spin echo EPI for compensating about deeply distortion aspect in case of post-operation patients in magnetic resonance image. A total of 100 patients were performed on 3.0 T(GE Signa Excite E2, USA) with 8ch head coil. As a result of analysis, The SNRs of whiter and gray matter areas were 36.74 $\pm$ 06 and 39.96 $\pm$ 09 in the gradient echo EPI, the SNRs which white and gray matter areas were slightly higher than gradient echo EPI(P<0.005, paired student t-test). It was 46.24 $\pm$ 11 and 51.38 $\pm$ 13 in gradient and spin echo EPI, respectively. The signal intensity in the whiter and gray matter areas also were 87.33 $\pm$ 15.24 and 140.66 $\pm$ 13.45 in the gradient echo EPI techniques, The signal intensity of gradient echo EPI showed higher values compared to spin echo EPI. Otherwise, gradient echo EPI technique is distortion enough to operation wound and edge of the image, while spin echo EPI technique did not appear almost. In this point, the spin echo EPI technique, after surgical operation according to patient state beside gradient echo EPI techniques that signalbeside gradient echo EPI techniques that signal intensity is high and patient's case which image distortion is serious by metal etc, will be provide the useful information in adults and pediatric patients.

자기공명영상 검사 시 음악을 이용하여 환자의 불안감 해소에 관한 고찰: 사례 보고

구은회,강수철,Goo, Eun-Hoe,Kang, Soo-Cheol 대한디지털의료영상학회 2009 대한디지털의료영상학회논문지 Vol.11 No.2

The purpose of this study is to know about solution of insecurity sense for solving the tediousness and inducing comfortableness in long time MRI examination. Studies were examined with total of 117 patients that the intention expression of self is possible for a month without dividing man and woman in november 2006. Examination methods were filled in questionnaire after testing using Siemens Impact 1.0T. The musical art were selected through intranet search and record sale inquiry using CD player and speaker. That kind of a music were selected with Korean classical music's 10 chapter, pop song 10's chapter, classic's 10 chapter and Korean popular song's 10 chapter. With analytical method, patients of under 40 year-old, or older and patients using ear-pad and head-phone were classified into groups. As analysis result with question item of questionnaire, most of the patients were showed a favor(36.72%) in playing a music, specially, examination of about 15.38% which uses the headphone prefer a music as older generation of over 40 year-old. In conclusion, with installing of the professional musical program in MRI test rooms, if listening to the music with selection by oneself before testing by season, age, time through development of appropriate musical program will be able to expect the more effect.

DCE 3D Breast MRI 검사 시 30 sec 이내에 혈류 역학적 정보에 대한 연구 : Experienced Reports

구은회,Goo, Eun-Hoe 대한디지털의료영상학회 2014 대한디지털의료영상학회논문지 Vol.16 No.1

The purpose of this study evaluated the hemo-dynamic information within 30 seconds clinically in 3D breast MRI. From January to March 2014, A total of 40 people were examined at 1.5 Tesla(Philips, Medical System, Achieva, The Netherlands) MRI equipments using 16 channel SENSE breast coil. The imaging parameters on vibrant are fellow as: $TR/TE/FA^{\circ}$/Matrix size/Slice thickness/Slab($5ms/2ms/10^{\circ}/180{\times}139{\times}2mm/80$). This study used a Gadovist and injected it with injection speed of 4 ml /sec by auto injector with 15 ml saline flushing. Firstly, for the delay time study, it divided three different delay time from immediately, 20 seconds, and 30 seconds. In quantitative analysis, the ROI signal intensities of tumor and surrounding tissues were measured retrospectively. In qualitative analysis, the image quality was scored from 1 to 5 point by one experienced radiological technologists as a visual test. The significance level of each delay time was evaluated with a one-way ANOVA(p<0.05). In the visual test, score levels on 30 seconds delay time was a little bit higher than others(p<0.05). The signal intensity of the tumor were $1445{\pm}360$, $1410{\pm}320$, $1510{\pm}415$ on immediately, 20 seconds, and 30 seconds and score levels were $4.18{\pm}0.85$, $3.54{\pm}0.94$, $4.45{\pm}0.74$(p<0.05). The data on immediate images showed better results than that others(p<0.05). Conclusively, Although it has been high scored in 30sec delay time for visual test in order to avoid failure in 20second, 30seconds delay time after contrast media administration, we recommend that the DCE 3D breast MRI commence immediately.

뇌손상 환자에서 SE, TSE, TGSE의 적용에 대한 비교 연구

구은회,방용식,신용환,김학문,김성룡,김동성,이용우,Goo Eun Hoe,Bang Yong Sik,Shin Yong Hwan,Kim Hak Moon,Kim Seong Ryong,Kim Dong Sung,Lee Yong Woo 대한방사선사협회 2001 대한방사선사협회지 Vol.27 No.2

I. Purpose : There are many kinds of MRI techniques and there have been new techniques spreading clinically with the development of software. Clinical diagnosis value has been comparatively studied by conducting the techniques of SE, TSE, and TGSE on the

여성골반에 대한 최적의 b-value(s/mm²)를 이용한 확산강조 자기공명영상의 정량적, 성적 평가

구은회,Goo, Eun-Hoe 한국디지털정책학회 2013 디지털융복합연구 Vol.11 No.1

본 연구의 목적은 악성 및 양성 여성골반 병변에서 자기공명 확산강조영상의 정량적, 정성적평가을 통하여 최적의 확산경사계수(b-values) 값을 구하고, 임상적 유용성을 알아보고자 하였다. 확산강조영상의 b-value($s/mm^2$)값을 600, 800, 1000, 1200, 1400까지 변화시키면서 얻었다. 정량적 분석결과 b-values 값 중 800에서 자궁근종의 평균 신호대 잡음비 $84.6{\pm}4.57$(p=0.024) 와 대조도대 잡음비 $50.13{\pm}5.47$(p=0.028)로 가장 높았고, 자궁경부암의 평균 신호대 잡음비 $12.0{\pm}2.04$(p=0.047)와 대조도대 잡음비 $10.6{\pm}1.24$(p=0.001)로 가장 높았으며, 이때 현성확산계수는 자궁근종 $1.19{\times}10^{-3}$(p=0.008), 자궁경부암 $0.96{\times}10^{-3}$(p=0.027) 이었다. 정성적 분석결과로서 병변의 묘출도와 명확성은 $4.02{\pm}0.18$(p=0.028), $4.39{\pm}0.25$(p=0.015)로 800에서 가장 높았다. 결론적으로 확산강조 자기공명영상은 여성골반 병변 검출에 있어서 중요한 방법이고, 최적의 b-value($s/mm^2$)값은 $800s/mm^2$ 이었으며, 정량적, 정성적 평가는 여성골반의 악성 및 양성 감별진단에 도움을 주었다. The purpose of this study is to know the clinical usefulness of optimal b-values by quantitative, qualitative evaluation of DW-MRI for lesions of benignity and malignity of female pelvis. The b-values used in DWI were 600, 800, 1000, 1200, 1400($s/mm^2$). Mean SNR and CNR of myoma in b-value 800 were the highest result as $84.6{\pm}4.57$(p=0.024) and $50.13{\pm}5.47$(p=0.028), Mean SNR and CNR of cervical cancer were the highest result as $12.0{\pm}2.04$(p=0.047) and $10.6{\pm}1.24$(p=0.001), Mean ADC value in myoma and cervical cancer in b-value 800 were $1.19{\times}10^{-3}mm^2/s$(p=0.008), $0.96{\times}10^{-3}mm^2/s$(p=0.027). As a qualitative analysis, the delineation and conspicuity were the highest result as $4.02{\pm}0.18$(p=0.028), $4.39{\pm}0.25$(p=0.015) on b-value 800. DW-MRI is an important method, and the optimal b values is 800 $s/mm^2$ for differentiation between benign and malignant lesions of female pelvis.

고 자장 기능적 MR 영상을 이용한 뇌 운동 영역에서 산소 주입에 따른 활성화 영역에 관한 연구

구은회,권대철,Goo, Eun-Hoe,Kweon, Dae-Cheol 대한인간공학회 2005 大韓人間工學會誌 Vol.24 No.4

This study aim to investigate the effects of supply of oxygen enhances cerebral activation through increased activation in the brain and using a 3 Tesla fMRI system. Five volunteers (right handed, average age of 21.3) were selected as subjects for this study. Oxygen supply equipment that provides 30% oxygen at a constant rate of 15L/min was given using face mask. A 3 Tesla fMRI system using the EPI BOLD technique, and three-pulse sequence technique get of the true axial planes scanned brain images. The author can get the perfusion images of the brain by oxygen inhalation with susceptibility contrast EPI sequence at the volunteers. Complex movement consisted of a finger task in which subjects flexed and extended all fingers repeatedly in union, without the fingers touching each other. Both task consisted of 96 phases including 6 activations and rests contents. Post-processing was done on MRDx software program by using cross-correlation method. The result shows that there was an improvement in performance and also increased activation in several areas in the oxygen method. These finding demonstrates that while performing cognitive tasks, oxygen administration was due to increase of cerebral activation.