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( Eui Seock Hwang ),( Kee Joon Choi ),( Duk Hyun Kang ),( Gi Byoung Nam ),( Jae Sik Jang ),( Young Hoon Jeong ),( Chang Hoon Lee ),( Ji Young Lee ),( Hyun Koo Park ),( Chong Hun Park ) 대한내과학회 2007 The Korean Journal of Internal Medicine Vol.22 No.4
Background: The prevalence and clinical significance of white-coat hypertension (WCHT) and masked hypertension (MHT) are unknown in Koreans. Here we measure the frequency of WCHT and MHT in hypertensive subjects and identify the epidemiologic and/or clinical factors that predict it in Korean subjects. Methods: This study is a retrospective analysis of a random sample from February 2004 to October 2005. All patients had measurements of blood pressure (BP) in the clinic and 24-hour ambulatory blood pressure monitoring (ABPM). Subjects were classified into four groups on the basis of daytime ambulatory BP and clinic BP level: 1) Normotension (NT), 2) MHT, 3) WCHT, and 4) sustained hypertension (SHT). Results: For all 967 patients, the mean clinic BP was 157.7±22.0/95.3±13.1 mmHg, and the mean daytime ambulatory BP was 136.4±15.0/86.2±10.7 mmHg. The NT, MHT, WCHT, and SHT groups consisted of 51 (5.3%), 55 (5.7%), 273 (28.2%), and 588 (60.8%) subjects, respectively. The left ventricular mass index was significantly higher in SHT than in the other groups, and was positively correlated with BP, especially ABPM. Compared with NT, the factors associated with MHT were younger age, male gender, higher BMI, clinic BP ≥130 mmHg, and alcohol consumption. Compared with SHT, the factors associated with WCHT were female gender, lower BMI, and clinic BP <150 mmHg. Conclusions: WCHT and MHT were prevalent in the hypertensive population. ABPM was more predictive of target organ damage than clinic BP, and could be useful in identifying subjects at risk for WCHT and MHT.
면역저하 환자에서의 Listeria Monocytogenes에 의한 균혈증-뇌막염
최강원,김병국,정문현,고은미,김의종,김노경 대한감염학회 1986 감염 Vol.18 No.2
Meningitis caused by Listeria monocytogenes has been known to occur frequently in the immunocompromised host. We have experienced three cases of Listeria monocytogenes bacteremia-meningitis in the patients with chronic myelogenous leukemia, with Hodgkin's disease, and with acute nonlymphocytic leukemia. With a summary of 9 cases reported in Korea, clinical features of three patients are described.
Choi, Eui-Young,Choi, Byoung Wook,Kim, Sung-Ai,Rhee, Sang Jae,Shim, Chi Young,Kim, Young Jin,Kang, Seok-Min,Ha, Jong-Won,Chung, Namsik Elsevier Science 2009 European journal of heart failure Vol.11 No.6
<P>AIMS: Despite the prognostic importance of ventricular filling and ventricular-arterial interaction in patients with advanced systolic heart failure, the structural determinants of these parameters have not been fully studied. We aimed to investigate whether patterns of late gadolinium enhancement (LGE) on cardiac magnetic resonance affect ventricular elastic properties or performance in patients with non-ischaemic dilated cardiomyopathy (DCM). METHODS AND RESULTS: Patients (n = 49) with markedly reduced systolic function (left ventricular (LV) ejection fraction <35%) due to longstanding non-ischaemic DCM underwent contrast-enhanced cardiac magnetic resonance after comprehensive echo-Doppler evaluations. The single beat-derived end-diastolic elastance, end-systolic elastance, arterial elastance, and dyssynchrony indices were measured by echo. On the basis of LGE patterns, patients could be divided into three groups: non-LGE (n = 18), non-midwall LGE (n = 13), and midwall LGE (n = 18). The midwall LGE group had lower LV systolic longitudinal velocity (4.6 +/- 1.7 for non-LGE vs. 4.3 +/- 1.2 for non-midwall LGE vs. 3.5 +/- 1.0 cm/s for midwall LGE, P = 0.025), higher end-diastolic elastance index (0.41 +/- 0.21 vs. 0.46 +/- 0.31 vs. 0.85 +/- 0.51 respectively, P = 0.008), and a more impaired ventriculoarterial coupling index (3.14 +/- 1.53 vs. 2.88 +/- 1.94 vs. 5.52 +/- 3.18, P = 0.006) than other subgroups. CONCLUSION: Patients with midwall LGE had a higher ventricular stiffness index and more impaired ventriculoarterial coupling when compared with other non-ischaemic DCM patients.</P>