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        Dental Caries Experience and Oral Health Practice among 12-Years-Old Schoolchildren

        Eman K. M. Mansur,Halima A. Ayyad,Raga A. Elzahaf 대한예방치과학회 2022 International Journal of Clinical Preventive Denti Vol.18 No.1

        Objectives: To assess the experience of dental caries and practice of oral health preventive measures. Methods: This was a secondary data study extracted from primary data through a cross-sectional study of a random sample of two hundred and forty-six 12 years-old Libyan schoolchildren (in 2019). Children underwent clinical examinations for dental caries experience. Then, they asked to complete a self-administrated questionnaire that designed to evaluate the oral health practices. The collected data were analysed using SPSS for Windows, version 25. The alpha value was 0.05. Results: The prevalence of dental caries, for the total sample, was 80.5% and the mean Decayed, Missing and Filled Teeth index (DMFT) was 2.4 (SD, 1.7). A clear gradient in the DMFT means with statistically significant was observed only across the categories of frequency of toothbrushing and frequency of sugary foods and drinks consumption in between meals. In addition, statistical significant was found for using fluoridated toothpaste. Conclusion: Dental caries in children aged 12 years old was prevalent in this study. The present survey provided an overview of practice of oral health preventive measures of participants, as the differences in these practices have influenced the DMFT values and provided knowledge about the disease experience.

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        Potential Role for a Panel of Immunohistochemical Markers in the Management of Endometrial Carcinoma

        Amany Salama,Mohammad Arafa,Eman ElZahaf,Abdelhadi Mohamed Shebl,Azmy Abd El-Hameed Awad,Sylvia A. Ashamallah,Reda Hemida,Anas Gamal,Abd AlRahman Foda,Khaled Zalata,El-Said M. Abdel-Hady 대한병리학회 2019 Journal of Pathology and Translational Medicine Vol.53 No.3

        Background: In order to improve the efficacy of endometrial carcinoma (EC) treatment, identifying prognostic factors for high risk patients is a high research priority. This study aimed to assess the relationships among the expression of estrogen receptors (ER), progesterone receptors (PR), human epidermal growth factor receptor 2 (HER2), Ki-67, and the different histopathological prognostic parameters in EC and to assess the value of these in the management of EC. Methods: We examined 109 cases of EC. Immunohistochemistry for ER, PR, HER2, and Ki-67 were evaluated in relation to age, tumor size, International Federation of Gynecology and Obstetrics (FIGO) stage and grade, depth of infiltration, cervical and ovarian involvement, lymphovascular space invasion (LVSI), and lymph node (LN) metastasis. Results: The mean age of patients in this study was 59.8 ± 8.2 years. Low ER and PR expression scores and high Ki-67 expression showed highly significant associations with non-endometrioid histology (p = .007, p < .001, and p < .001, respectively) and poor differentiation (p = .007, p < .001, and p <. 001, respectively). Low PR score showed a significant association with advanced stage (p = .009). Low ER score was highly associated with LVSI (p = .006), and low PR scores were associated significantly with LN metastasis (p = .026). HER2 expression was significantly related to advanced stages (p = .04), increased depth of infiltration (p = .02), LVSI (p = .017), ovarian involvement (p = .038), and LN metastasis (p = .038). There was a close relationship between HER2 expression and uterine cervical involvement (p = .009). Higher Ki-67 values were associated with LN involvement (p = .012). Conclusions: The over-expression of HER2 and Ki-67 and low expression of ER and PR indicate a more malignant EC behavior. An immunohistochemical panel for the identification of high risk tumors can contribute significantly to prognostic assessments.

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