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RISS 인기검색어
- 검색키워드
- 저자 : Dutta Pallav (검색결과 4 건)
- 무료
- 기관 내 무료
- 유료
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Grey Wolf Optimizer Based PID Controller for Speed Control of BLDC Motor
Dutta Pallav,Nayak Santanu Kumar 대한전기학회 2021 Journal of Electrical Engineering & Technology Vol.16 No.2
A BLDC motor is superior to a brushed DC motor, as it replaces the mechanical commutation unit with an electronic one; hence improving the dynamic characteristics, effi ciency and reducing the noise level marginally. Maximum BLDC motor drives use PID controller to control the speed of the machine; because it is simple in structure, relatively cheaper and exhibits good performance. But the main problem associated with PID controller is adjusting its parameters during implementation. In recent works, it has been observed that Particle Swarm Optimization (PSO) technique showed good performance in tuning PID controller. For this purpose, in this article, “Grey Wolf Optimization” (GWO) algorithm is introduced; which is used to optimally tune the PID controller parameters. The objective of this article is to compare the results obtained for tuning of PID controller based on of GWO and PSO technique and a conclusion has been derived that the proposed approach yields superior dynamic performance for BLDC motor.
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Ahmed T Alahmar,Pallav Sengupta,Sulagna Dutta,Aldo E. Calogero 대한생식의학회 2021 Clinical and Experimental Reproductive Medicine Vol.48 No.2
Objective: Oxidative stress (OS) plays a key role in the etiology of unexplained male infertility. Coenzyme Q10 (CoQ10) is a potent antioxidant that may improve semen quality and OS in infertile men with idiopathic oligoasthenoteratospermia (OAT), but the underlying mechanism is unknown. Therefore, the present study was undertaken to investigate the effect of CoQ10 on OS markers and sperm DNA damage in infertile patients with idiopathic OAT. Methods: This prospective controlled study included 50 patients with idiopathic OAT and 50 fertile men who served as controls. All patients underwent a comprehensive medical assessment. Patients and controls received 200 mg of oral CoQ10 once daily for 3 months. Semen and blood were collected and analyzed for sperm parameters, seminal CoQ10 levels, reactive oxygen species (ROS) levels, total antioxidant capacity, catalase, sperm DNA fragmentation (SDF), and serum hormonal profile. Results: The administration of CoQ10 to patients with idiopathic OAT significantly improved sperm quality and seminal antioxidant status and significantly reduced total ROS and SDF levels compared to pre-treatment values. Conclusion: CoQ10, at a dose of 200 mg/day for 3 months, may be a potential therapy for infertile patients with idiopathic OAT, as it improved sperm parameters and reduced OS and SDF in these patients.
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Alahmar Ahmed T.,Calogero Aldo E.,Sengupta Pallav,Dutta Sulagna 대한남성과학회 2021 The World Journal of Men's Health Vol.39 No.2
Purpose: Oxidative stress and sperm DNA fragmentation (SDF) are potential contributing factors for idiopathic male infertility. Coenzyme Q10 (CoQ10) have been reported to be effective in the treatment of idiopathic male infertility, in general, owing to its antioxidant properties. Thus, the present study intends to investigate the effects of CoQ10 therapy on semen parameters, oxidative stress markers and SDF in infertile men, specifically with idiopathic oligoasthenozoospermia (OA). Materials and Methods: In this case-control study, sixty-five infertile patients with idiopathic OA and forty fertile men (control) were included. All participants underwent semen analysis based on the World Health Organization guidelines (5th edition, 2010). Patients received CoQ10 at the dose of 200 mg/d orally for three months. Seminal plasma CoQ10, total antioxidant capacity (TAC), total reactive oxygen species (ROS), glutathione peroxidase (GPx), and SDF levels were measured in controls (baseline) and infertile patients pre- and post-CoQ10 treatment. Results: CoQ10 treatment for three months significantly improved sperm concentration (p<0.05), progressive motility (p<0.05), total motility (p<0.01), seminal fluid CoQ10 concentration (p<0.001), TAC (p<0.001), and GPx (p<0.001) levels in infertile men with OA. Further, ROS level (p<0.05) and SDF percentage (p<0.001) were reduced in OA patients as compared to the baseline. CoQ10 levels also correlated positively with sperm concentration (r=0.48, p=0.01) and total motility (r=0.59, p=0.003) while a negative correlation was recorded between SDF and sperm motility (r=-0.54, p=0.006). Conclusions: CoQ10 supplementation for three months could improve semen parameters, oxidative stress markers and reduce SDF in infertile men with idiopathic OA.
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Coenzyme Q10, oxidative stress, and male infertility: A review
Ahmed T. Alahmar,Aldo E. Calogero,Rajender Singh,Rossella Cannarella,Pallav Sengupta,Sulagna Dutta 대한생식의학회 2021 Clinical and Experimental Reproductive Medicine Vol.48 No.2
Male infertility has a complex etiopathology, which mostly remains elusive. Although research has claimed that oxidative stress (OS) is the most likely underlying mechanism of idiopathic male infertility, the specific treatment of OS-mediated male infertility requires further investigation. Coenzyme Q10 (CoQ10), a vitamin-like substance, has been found in measurable levels in human semen. It exhibits essential metabolic and antioxidant functions, as well as playing a vital role in mitochondrial bioenergetics. Thus, CoQ10 may be a key player in the maintenance of biological redox balance. CoQ10 concentrations in seminal plasma directly correlate with semen parameters, especially sperm count and sperm motility. Seminal CoQ10 concentrations have been shown to be altered in various male infertility states, such as varicocele, asthenozoospermia, and medical or surgical regimens used to treat male infertility. These observations imply that CoQ10 plays an important physiological role in the maintenance and amelioration of semen quality. The present article thereby aimed to review the possible mechanisms through which CoQ10 plays a role in the regulation of male reproductive function, and to concisely discuss its efficacy as an ameliorative agent in restoring semen parameters in male infertility, as well as its impact on OS markers, sperm DNA fragmentation, pregnancy, and assisted reproductive technology outcomes.
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