Research on the Optimization of the Performance of CTL Loop Discriminator

Xu Ying,Yuan Hong,Luo Ruidan,Xu Duo 보안공학연구지원센터 2015 International Journal of Future Generation Communi Vol.8 No.5

Chip Tracking Loop (CTL) is the key to ensure the accuracy of regenerative pseudo-noise ranging in the deep space measurement and control communication system. However, due to the impact of the code imbalance, clock attenuation rate and noise, the loop locking time of CTL is prolonged and the ranging accuracy is degraded. In this paper, we proposed the discriminator optimization algorithm to address this problem. This algorithm is based on the loop discrimination performance of clock code and composite code, and the impact of the noise on the discrimination performance. In order to improve the tracking accuracy and shorten the loop locking time, this algorithm corrected the curve of discriminator’s gain by compensating discriminator’s gain. Both the theory analysis and simulation results illustrate that the algorithm can correct the discriminator’s gain curve, reduce the loop locking time and ensure the significant tracking accuracy in low SNR.

Novel Structural Composite Yarns Spun with Harmonic Migrations of Filaments

Duo Xu,Hang Fan,Wangwang Yang,Keshuai Liu,Weilin Xu 한국섬유공학회 2022 Fibers and polymers Vol.23 No.6

A novel structural composite yarn was fabricated by periodically forcing filaments with harmonic migrations toenhance the cooperativity between filaments and staple fibers. The geometrical principle of yarn structure variations causedby harmonic migrations of filaments was theoretically analyzed, then demonstrated the influences of filament’s positions ondifferent shapes of the composite spinning-triangle zone. Further, the novel structural composite yarn structure was comparedto the seven models of composite yarns which were established with different filament’s positions, showing a varied filamenthelical structure to capture and then lock internal and external staple fibers, distinguishing that other composite yarns inliterature. Then, a synergetic eccentric device was employed to oscillate two filaments to conduct confirmatory tests. Theonline observations of the dynamic spinning-triangle zone were technically applied to evaluate the filaments’ harmonicmigrations. Furthermore, the yarn structural variations were caused by various geometrical configurations. Experimentalresults exhibited that the novel structural composite yarn had relatively fewer hairiness, medium irregularity, and strengthafter comparisons with other composite yarns. Altogether, the cyclically harmonic migrations of filaments were promising asan efficient and novel method for control the configurations between filaments and staple fibers.

Anthocyanins From Black Soybean Seed Coat Enhance Wound Healing

Xu, Lianji,Choi, Tae Hyun,Kim, Sukwha,Kim, Sang-Hyon,Chang, Hyuk Won,Choe, Misun,Kwon, Sun Young,Hur, Ji An,Shin, Sung Chul,Chung, Jong Il,Kang, Dawon,Zhang, Duo by Lippincott Williams Wilkins 2013 Annals of plastic surgery Vol.71 No.4

ABSTRACT: Anthocyanins are known to have antioxidant and antiinflammatory effects. We hypothesized that anthocyanins would enhance wound healing in Sprague-Dawley rats. The purpose of this study was to evaluate our hypothesis and investigate the mechanism of wound healing enhancement. The cytoprotective effect of an immortalized epidermal keratinocyte cell line (HaCaT) and human neonatal dermal fibroblasts in response to various concentrations of anthocyanins was determined. Vascular endothelial growth factor (VEGF) and thrombospondin 1 (TSP1) of HaCaT were measured by Western blot analysis. Anthocyanins were applied to the wounds in rats, and the healing ratio was calculated. Tissue VEGF, TSP1, CD31, nuclear factor-&kgr;B, and phosphorylation of I&kgr;Bα were measured. The viability of the HaCaT cell line and human neonatal dermal fibroblasts increased under cytotoxicity by H2O2 in the anthocyanin-treated groups. The VEGF in the anthocyanin-treated groups increased, whereas TSP1 decreased. Wounds in the experimental groups healed faster, and VEGF and CD31 increased in the experimental groups, whereas TSP1 decreased. Anthocyanins inhibited the translocation of nuclear factor-&kgr;B (p65) from cytosol to nucleus and also prevented the phosphorylation of I&kgr;Bα. Anthocyanins enhance wound healing through a cytoprotective effect, enhancement of angiogenesis, and an antiinflammatory effect.

Gefitinib Alone or with Concomitant Whole Brain Radiotherapy for Patients with Brain Metastasis from Non-small-cell Lung Cancer: A Retrospective Study

Zeng, Yin-Duo,Zhang, Li,Liao, Hai,Liang, Ying,Xu, Fei,Liu, Jun-Ling,Dinglin, Xiao-Xiao,Chen, Li-Kun Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.3

Background: Gefitinib, a tyrosine kinase inhibitor (TKI) of epidermal growth factor receptor (EGFR), is used both as a single drug and concurrently with whole brain radiotherapy (WBRT) the standard treatment for brain metastases (BM), and is reported to be effective in a few small studies of patients with BM from non-small-cell lung cancer (NSCLC). However, no study has compared the two treatment modalities. This retrospective analysis was conducted to compare the efficacy of gefitinib alone with gefitinib plus concomitant WBRT in treatment of BM from NSCLC. Methods: We retrospectively reviewed 90 patients with BM from NSCLC who received gefitinib alone (250mg/day, gefitinib group) or with concomitant WBRT (40Gy/20f/4w, gefitinib-WBRT group) between September 2005 and September 2009 at Sun Yat-Sen University Cancer Center. Forty-five patients were in each group. Results: The objective response rate of BM was significantly higher in gefitinib-WBRT group (64.4%) compared with gefitinib group (26.7%, P<0.001). The disease control rate of BM was 71.1% in gefitinib-WBRT group and 42.2% in gefitinib group (P=0.006). The median time to progression of BM was 10.6 months in gefitinib-WBRT group and 6.57 months in gefitinib group (P<0.001). The median overall survival(OS) of gefitinib-WBRT and gefitinib alone group was 23.40 months and 14.83 months, respectively (HR, 0.432, P=0.002). Conclusion: Gefitinib plus concomitant WBRT had higher response rate of BM and significant improvement in OS compared with gefitinib alone in treatment of BM from NSCLC.

Preparation of Silver Nanocap Arrays and Their Surface-enhanced Raman Scattering Activity

Chunxu Wang,Duo Xu,Yuhai Wang,Li Wang,Lei Chen,Xiangxin Xue,Zhengkun Qin 대한화학회 2017 Bulletin of the Korean Chemical Society Vol.38 No.10

In this article, a surface-enhanced Raman scattering (SERS) substrate of silver nanocap arrays was reported. With increasing the size of nanocaps, the localized surface plasmon resonance (LSPR) of the arrays exhibited tunable ability in the visible spectral region. The optical response of the nanocap arrays stimulated their use in SERS experiments. The assessment of SERS activity of the nanocap arrays was performed by using the 514.5 nm excitation line, and different average enhancement factor (EF) values were obtained. The good tunability of LSPR, relatively high average EF values and long-range order of these substrates suggest that the silver nanocap arrays have promising applications as functional components in spectroscopy, immunoassay, biosensors, and biochips.

QUANTIFYING DARK GAS

LI, DI,XU, DUO,HEILES, CARL,PAN, ZHICHEN,TANG, NINGYU The Korean Astronomical Society 2015 天文學論叢 Vol.30 No.2

A growing body of evidence has been supporting the existence of so-called "dark molecular gas" (DMG), which is invisible in the most common tracer of molecular gas, i.e., CO rotational emission. DMG is believed to be the main gas component of the intermediate extinction region from Av~0.05-2, roughly corresponding to the self-shielding threshold of $H_2$ and $^{13}CO$. To quantify DMG relative to $H{\small{I}}$ and CO, we are pursuing three observational techniques; $H{\small{I}}$ self-absorption, OH absorption, and THz $C^+$ emission. In this paper, we focus on preliminary results from a CO and OH absorption survey of DMG candidates. Our analysis shows that the OH excitation temperature is close to that of the Galactic continuum background and that OH is a good DMG tracer co-existing with molecular hydrogen in regions without CO. Through systematic "absorption mapping" by the Square Kilometer Array (SKA) and ALMA, we will have unprecedented, comprehensive knowledge of the ISM components including DMG in terms of their temperature and density, which will impact our understanding of galaxy evolution and star formation profoundly.

한(韓)ㆍ중(中) 문화교류를 통한 전통조경의 비교 연구

펑홍쉬 ( Peng Hong-xu ),장징 ( Zhang Jing ),장치엔두어 ( Jiang Qian-duo ),노재현 ( Rho Jae-hyun ) 한국전통조경학회(구 한국정원학회) 2020 한국전통조경학회지 Vol.38 No.4

전통조경은 선현(先賢)들이 현대사회에게 남긴 문화적 자산으로, 고대의 전통문화를 이해할 수 있을 뿐만 아니라 현대의 조경설계에도 새롭고 창의적인 소재를 제공할 수 있다. 한ㆍ중 양국은 고대부터 문화교류를 통해 전통 조경문화의 계승과 보호 및 발전을 이루었을 뿐만 아니라 ‘전통과 현대’ 및 '지역성과 국제성'이 서로 어우러져 발전하여 왔음은 익히 잘 알려져 있다. 본 연구는 한ㆍ중 전통조경의 비교 연구를 목적으로 우선 양국 전통조경문화를 선행연구 문헌을 통해 분석하였다. 다음으로 양국의 문화적 배경을 종교사상, 전통문화, 자연관으로 나눠 해석하고 양국의 조경 역사와 원류관계를 조명하였다. 이를 바탕으로 한ㆍ중 조경 사조(思潮)의 비교 및 전통조경의 발전과정, 한ㆍ중 조경의 예술적 공간과 경지(境地) 등 세 방향에서 분석 고찰하였으며, 양국의 전통조경의 조성 방식에 있어 차이점을 분석하고, ‘의경조성’ 및 ‘의경수법’을 구명하였다. 특히 본 연구에서는 전통조경의 이론적 배경 및 조경의 경의성(景意性)에 대해 전통조경의 배치 및 주변 환경과 형식 그리고 전통조경의 색채 등을 명ㆍ청시대의 ‘이화원(頤和園)’과 조선 시대의 ‘경복궁(景福宮)’을 사례대상으로 비교 분석하였다. 이를 통하여 한ㆍ중 조경의 특징을 토대로 국제화를 위한 전통적인 조경문화의 계승과 혁신방안을 모색하였다. 한ㆍ중 조경사의 발전 추세에 따른 양국 간 문화교류의 중요성은 아무리 강조해도 지나치지 않다. 앞으로 양국 조경의 발전은 전통문화에 대한 국제 간 협력 및 지역 특색의 창조적 결합, 화이부동(和而不同)한 전통조경 환경의 조성, 다양한 문화의 다층적 상생이 양국의 우호증진에도 기여할 것으로 기대된다. Traditional landscape is a cultural asset left by Seonhyeon to modern society, and it can not only understand the landscape culture of ancient tradition but also provides / provided a new creative material for modern landscape designs / designed. However, it is well known that Korea and China have a relationship between the development and exchange of landscaping in a global background, the succession of traditional landscape architecture culture in a global background covers many dimensions, including protection, development and innovation, and that "traditional and modern" and "regionally and internationality" should be harmonized with each other. This study uses traditional Korean and Chinese landscaping buildings as research subjects to extract and organize related data through various channels, including basic literature research that understands the history and culture of the two countries. I interpreted the cultural backgrounds of the two countries by dividing them into religious ideas, traditional culture, and natural views, and highlighted the history of development and the relationship between the two countries. Based on this, it analyzed the differences created by traditional landscaping between Korea and China, and also specifically analyzed the "creation of righteous army" and "the law of righteous army." In particular, this study sought to inherit and innovate traditional landscape culture for the internationalization of "One Belt, One Road" based on the characteristics of Korea and China's landscape through a comparative analysis of the construction elements and methods of Yihwawon of the Ming and Qing periods and Gyeongbokgung Palace of the Joseon Dynasty on the theoretical background of landscaping and the significance of landscaping. The direction for the development and exchange with landscaping between the two countries was presented in line with the development trend of Korea-China landscaping in the global environment. In the future, the development of landscaping between the two countries is expected to be key to international cooperation in traditional culture, creative combination of local characteristics, creation of a harmonious landscape architecture environment, and co-prosperity of various cultures.

Prevalence of BRCA1 and BRCA2 Germline Mutations in Breast Cancer Women of Multiple Ethnic Region in Northwest China

Jianghua Ou,Tao Wu,Rolf Sijmons,Duo Ni1,Wenting Xu,Halmurat Upur 한국유방암학회 2013 Journal of breast cancer Vol.16 No.1

Purpose: The aim of this study is to further understand the status of BRCA1 and BRCA2 mutation among Chinese high-risk breast cancer patients in multiple-ethnic regions of China. Methods: A total of 79 blood samples of high-risk breast cancer patients from Xinjiang Uyghur autonomous region were analyzed by PCR-DHPLC sequencing analysis. Results: Analysis with full length of the two genes identified a total of 6 deleterious mutations (2073delA, 2394C-T [Q759X] and IVS16+1G>A in BRCA1; 1627A-T [K467X], 6873delCTCC and 9481delA in BRCA2) in this cohort. The prevalence of BRCA1/2 germline mutation was about 7.6% (6/79) in the Xinjiang multiple ethnic region of China. Among them, 3 novel deleterious mutations, 2073delA in BRCA1 (Han ethnic Chinese) and BRCA2 variants 6873delCTCC and 9481delA (both are Kazakh ethnic Chinese), were identified and they had never been reported in breast cancer information core (BIC) database before. 2394C-T (Q759X) and IVS16+1G>A, in BRCA1 and BRCA2 variants 1627A-T were previously reported in other populations but not Chinese. Among 6 of the BRCA-related tumors, three BRCA1- and one BRCA2-associated tumors were in triple negative (estrogen receptor, progesterone receptor, and HER2 negative expressed) status and exhibited a high tumor grade. So far none of these 6 deleterious mutations were reported in ethnic Han Chinese. Conclusion: BRCA germline mutation in Chinese multiple ethnicity region may exhibit different genotypes compared to ethnic Han Chinese in other regions. These differences may arise from interaction of genetic background and environmental factors.

A Spectroscopic Study on Singlet Oxygen Production from Different Reaction Paths Using Solid Inorganic Peroxides as Starting Materials

Li, Qingwei,Chen, Fang,Zhao, Weili,Xu, Mingxiu,Fang, Benjie,Zhang, Yuelong,Duo, Liping,Jin, Yuqi,Sang, Fengting Korean Chemical Society 2007 Bulletin of the Korean Chemical Society Vol.28 No.10

Using solid inorganic peroxides (including Li2O2, Na2O2, SrO2 and BaO2) as starting materials, three reaction paths for singlet oxygen (1O2) production were developed and studied. Their 1O2 emission spectra in the near- IR region and visible region from these reaction paths were simultaneously recorded by a near-IR sensitive Optical Multichannel Analyzer and a visible sensitive Optical Spectrum Analyzer, respectively. The comparison of their 1O2 emission spectra indicated that: (1) in term of the efficiency for 1O2 production, the gasliquid- solid reaction path (in which Cl2 or HCl and H2O reacted with the solid inorganic peroxides suspension in CCl4) was prior to the gas-solid reaction path (in which Cl2 or HCl reacted with the solid inorganic peroxides suspension in CCl4), but was inferior to the gas-liquid reaction path (in which Cl2 or HCl reacted with the solid inorganic peroxides solution in H2O or D2O); (2) the alkali metal peroxides (such as Li2O2 and Na2O2) was prior to the alkaline earth metal peroxides (such as SrO2 and BaO2) as the solid reactants, and Cl2 was favorable than HCl as the gas reactant in efficiency for 1O2 production in these reaction paths.

A Spectroscopic Study on Singlet Oxygen Production from Different Reaction Paths Using Solid Inorganic Peroxides as Starting Materials

Qingwei Li*,Fang Chen,Weili Zhao,Mingxiu Xu,Benjie Fang,Yuelong Zhang,Liping Duo,Yuqi Jin,Fengting Sang 대한화학회 2007 Bulletin of the Korean Chemical Society Vol.28 No.10

Using solid inorganic peroxides (including Li2O2, Na2O2, SrO2 and BaO2) as starting materials, three reaction paths for singlet oxygen (1O2) production were developed and studied. Their 1O2 emission spectra in the near-IR region and visible region from these reaction paths were simultaneously recorded by a near-IR sensitive Optical Multichannel Analyzer and a visible sensitive Optical Spectrum Analyzer, respectively. The comparison of their 1O2 emission spectra indicated that: (1) in term of the efficiency for 1O2 production, the gas-liquid-solid reaction path (in which Cl2 or HCl and H2O reacted with the solid inorganic peroxides suspension in CCl4) was prior to the gas-solid reaction path (in which Cl2 or HCl reacted with the solid inorganic peroxides suspension in CCl4), but was inferior to the gas-liquid reaction path (in which Cl2 or HCl reacted with the solid inorganic peroxides solution in H2O or D2O); (2) the alkali metal peroxides (such as Li2O2 and Na2O2) was prior to the alkaline earth metal peroxides (such as SrO2 and BaO2) as the solid reactants, and Cl2 was favorable than HCl as the gas reactant in efficiency for 1O2 production in these reaction paths.