http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
3DIV: A 3D-genome Interaction Viewer and database
Yang, Dongchan,Jang, Insu,Choi, Jinhyuk,Kim, Min-Seo,Lee, Andrew J,Kim, Hyunwoong,Eom, Junghyun,Kim, Dongsup,Jung, Inkyung,Lee, Byungwook Oxford University Press 2018 Nucleic acids research Vol.46 No.d1
<P><B>Abstract</B></P><P>Three-dimensional (3D) chromatin structure is an emerging paradigm for understanding gene regulation mechanisms. Hi-C (high-throughput chromatin conformation capture), a method to detect long-range chromatin interactions, allows extensive genome-wide investigation of 3D chromatin structure. However, broad application of Hi-C data have been hindered by the level of complexity in processing Hi-C data and the large size of raw sequencing data. In order to overcome these limitations, we constructed a database named 3DIV (a 3D-genome Interaction Viewer and database) that provides a list of long-range chromatin interaction partners for the queried locus with genomic and epigenomic annotations. 3DIV is the first of its kind to collect all publicly available human Hi-C data to provide 66 billion uniformly processed raw Hi-C read pairs obtained from 80 different human cell/tissue types. In contrast to other databases, 3DIV uniquely provides normalized chromatin interaction frequencies against genomic distance dependent background signals and a dynamic browsing visualization tool for the listed interactions, which could greatly advance the interpretation of chromatin interactions. ‘3DIV’ is available at http://kobic.kr/3div.</P>
통계적 기법에 의한 낙동강하구 점성토 지반의 피에조콘 계수 산정
김영훈(Kim Younghun),장정호(Jang Jungho),최동찬(Choi Dongchan),천병식(Chun Byungsik) 한국지반환경공학회 2009 한국지반환경공학회논문집 Vol.10 No.7
피에조콘 관입시험 중 점성토층 비배수 전단강도를 산정할 때 적용되는 피에조콘 계수는 시험현장에 따라 피에조콘 계수산정을 해야 한다. 경험적 해석방법의 경우에도 피에조콘 계수 산정을 위한 많은 방법들이 제안되어 왔으나, 대부분 국외에서 개발한 상관식이나 도표 등을 활용하여 국내 지반에 적용하므로, 이에 대한 적용성이 한계가 있다. 따라서 신뢰성 있는 피에조콘 계수를 산정하기 위해서는 대상지반의 특성을 비롯하여 비교대상 시험방법들의 연구가 필요하며, 국내지반에 대한 시험결과를 바탕으로한 피에조콘 계수를 산정할 필요가 있다. 본 연구에서는 낙동강 하구에 분포하는 연약점성토 특성을 파악하기 위해서 시추조사를 비롯한 현장시험 및 실내시험을 수행하였으며, 이 결과들을 피에조콘 관입시험과 비교 ? 분석하였다. 또한, 각 시험별 비배수 전단강도 특성을 분석하고, 피에조콘 관입저항치와 비교하여 피에조콘 계수를 구하고, 구한 피에조콘 계수를 통계적 기법을 적용하여 연구대상 지역의 신뢰성 높은 피에조콘 계수를 산정하였다. Recently, the importance of investigation for soft ground has been raised, so that various techniques of the investigation for soft ground are being introduced and applied. In particular, Piezocone penetration test has been utilized frequently home and abroad to identify many features of grounds precisely and gain various results in accordance with dividing strata and depth constantly by measuring continuously. In this study, to identify some features of soft clays distributed in the estuary of Nakdong river, researchers conducted field tests and laboratory tests with boring tests, and analyzed and compared with Piezocone penetration test. In addition, credible Piezocone factor of communities of subjects for this study was estimated to analyze some features of undrained shear strength of clay and calculate Piezocone factor compared with corrected cone resistance and apply some statistical techniques to estimated Piezocone factor.
Almomani, Belal,Kim, Seyeon,Jang, Dongchan,Lee, Sanghoon Korean Nuclear Society 2020 Nuclear Engineering and Technology Vol.52 No.5
A parametric study of several parameters relevant to design safety on the spent nuclear fuel (SNF) rod response under a drop accident is presented. In the view of the complexity of interactions between the independent safety-related parameters, a factorial design of experiment is employed as an efficient method to investigate the main effects and the interactions between them. A detailed single full-length fuel rod is used with consideration of post-irradiated fuel conditions under horizontal and vertical free-drops onto an unyielding surface using finite-element analysis. Critical drop heights and critical g-loads that yield the threshold plastic strain in the cladding are numerically estimated to evaluate the fuel rod structural resistance to impact load. The combinatory effects of four uncertain parameters (pellet-cladding interfacial bonding, material properties, spacer grid stiffness, rod internal pressure) and the interactions between them on the fuel rod response are investigated. The principal finding of this research showed that the effects of above-mentioned parameters on the load-carrying capacity of fuel rod are significantly different. This study could help to prioritize the importance of data in managing and studying the structural integrity of the SNF.