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기저세포암 및 편평세포암에서 미세혈관밀도와 p53 단백 발현에 관한 연구
어수락,조규성,안호범,김대영,이삼용,조백현 大韓成形外科學會 1999 Archives of Plastic Surgery Vol.26 No.3
Basal cell carcinoma(BCC) and squamous cell carcinoma (SCC) are very prevalent neoplasms of the human skin. Ultraviolet radiation in sunlight is a well-established mutagen of the p53 gene and is one of basal cell carcinoma and squamous cell carcinoma. The newly-formed vascular network is important for neoplasms to grow beyond a size of about 1 ㎣. Recent reports have suggested the hypothesis that a mutant p53 protein is closely related with capillary density. Immumohistochemistry for p53 protein and CD34 was performed in 20 cases of BCCs and 14 SCCs to evaluated the relationship between p53 protein and capillary density. The results were as follows:1. The microvessels stained by CD34 were mainly located in the interface of tumor cells and stroma. 2. There was no difference in the microvessel density according to the histologic types and age of the patients, but a higher microvessel density was noted in male patients. 3. The aggressive BCCs and the less-differentiated SCCs showed higher p53 immunostaining. 4. The mean microvessel density of cases showing strong positive immunostaining of the p53 gene(54.73±17.75) was higher than that of others(39.75±18.30). These results suggested that p53 protein expression and microvessel density are not related to the histologic types and age of the patients, but that differentiation and biologic behavior such as the infiltrating property of tumors and the microvessel density are closely related to p53 protein expression.
심포지움,특별강연 및 일반연제 발표 : 한국인 상염색체 우성 다낭신 환자의 PKD1과 PKD2 유전자 돌연변이 분석
어현선 ( Eo Hyeon Seon ),안규리 ( An Gyu Li ),채희진 ( Chae Hui Jin ),이은주 ( Lee Eun Ju ),황영환 ( Hwang Yeong Hwan ),황대연 ( Hwang Dae Yeon ),이중건 ( Lee Jung Geon ),김연수 ( Kim Yeon Su ),한진석 ( Han Jin Seog ),김성권 ( Kim 대한신장학회 2000 춘계학술대회 초록집 Vol.19 No.2
김광석,어수락,김대영,이삼용,조백헌 大韓成形外科學會 2000 Archives of Plastic Surgery Vol.27 No.1
As the use of free tissue reconstruction becomes more routine, attention is being focused not only on flap survival, but also on functional refinements in these flaps. One of the more important aspects of improving the outcome of these reconstruction may relate to the return of sensation. The anterolateral thigh free flap is based on the descending branch of the lateral circumflex femoral artery. This fasciocutaneous flap is indicated whenever a relatively thin flap is required in reconstruction. A neurosensory flap can be employed based on the anterior branched of the lateral femoral cutaneous nerve of the thigh. Since 1996, 15 patients with soft tissue defect on various regious were treated by using the anterolateral thigh sensate free falp. All flaps survived without total loss. Anastomosis of the sensible nerve on the recipient site with the anterior branch of the lateral femoral cutaneous nerve of the thigh was performed. All patients showed recovery of sensation in the anterolateral thigh sensate free falp beginning between the 4th and 6th month postoperatively. Follow-up periods ranged from 8 to 34 months and the results of sensory recovery were satisfactory. Therefore, resensitization of an anterolateral thigh free flap should be attempted by a nerve anastomosis in this transplant. The longterm success in this study suggests the benefits of microsurgical neurotization in free tissue transplantation.
표준편차 값의 자동 임계값 결정을 통한 Time-of-Flight 카메라의 플라잉 화소 (flying pixels) 제거
김대성(Kim, Dae Sung),어양담(Eo, Yang Dam),편무욱,문수정(Moon, Su Jung),조용원(Cho, Yong Won),장일웅,배상원 한국측량학회 2013 한국측량학회 학술대회자료집 Vol.2013 No.4
This study proposes the method for removing the flying points of TOF (Time-of-Flight) camera through the automatic thresholding determination of standard deviation. The proposed method and previous method using the confidence image were compared. Our method showed the possibility of automatic and objective method for flying points removal with the comparison.
SETTLING VELOCITY DISTRIBUTION OF MUDDY SEDIMENTS FROM SAEMANKEUM, WEST COAST OF KOREA
황규남,Jae Youn Lee,Dae Su Eo,조용준 한국해안해양공학회 1999 학술강연회 발표논문초록집 Vol.1 No.1
An experiment was conducted with muddy sediments from Saemankeum Project Site to quantify its settling velocity, using a specially designed 1.8 m tall settling column. Since settling velocity of muddy sediment is known to strongly vary with concentration in suspension, an effort has been made to examine the settling velocity in concentration. It is shown that settling velocity variation for Saemankeum mud is in the range of two orders of magnitude (from 0.01 to 1 ㎜/sec) over the corresponding concentration range of I to 60 g/L. A feature of settling velocity profile for Saemankeum mud is quite different in quantity as compared to those of previous studies with mud of other regions: Tampa Bay and Severn Estuary. Its settling velocities were relatively lower in the low concentration range than those for Tampa Bay and Severn Estuary mud. Particularly, its peak settling velocity occurs at very high concentration, which is about 5 times higher than those of Severn Estuary mud and Tampa Bay mud. It is concluded that magnitude of settling velocities of muddy sediments can be quite different regionally depending on its physico-chemical properties. It means that field or laboratory experiments for settling velocity measurement should be preceded over the numerical modeling of muddy sediment transport in order to obtain the reliable prediction results for a given specific site.
어대수,최강원,강상기,Eo Dae-su,Choi Kang-won,Kang Sang-ki 한국관개배수위원회 1999 한국관개배수논문집 Vol.6 No.1
One of the important features of a beach face is the dynamic response to the ever-changing waves and tides imposed from the body of water. Furthermore, human activities at or near the beach can enforce the characteristic changes on tidal motions and wave
박영욱 ( Park Yeong Wok ),어대수 ( Eo Dae Su ),박상현 ( Park Sang Hyun ) 한국농공학회 2000 한국농공학회 학술대회초록집 Vol.2000 No.-
Sea dike construction for the tidal flat reclamation works in estuary and coast may change the characteristics of tidal motion and wave conditions in the region. In turn, a new hydraulic condition provides the impacts on sediment transport pattern and forms a new morphological environment. Also, morphological changes during the closure works of sea dike are closely related with a safy of sea dike. Therefore, the prediction of morphological changes is required secure the safe closure work and the economic design of sea dikes. To investigate morphological changes due to sea dike construction, hydrodynamic changes of tides and waves have to be evaluated, then sediment transport and sea bottom changes are computed. Mathematical modelling is required for representation of interrelation of tidal motion, wave and sediment transport. In this study, numerical model MORSYS is applied to compute the hydrodynamics and morphological changes around the closure gap for Saemankuem dike. This model allows a flexible integration of the module for waves, currents, sediment transport and bottom changes.
Lee, Hee-Jun,Choi, Kang-Won,Eo, Dae-Su,Chu, Yong-Shik The Korean Society of Oceanography 2001 Journal of the Korean Society of Oceanography Vol.36 No.3
The progress of giant dyke construction off the Mangyung and Donajin rivers, has yielded enormous impact on the estuarine environment, both hydrodynamically and sedimentologically. Especially the inter-dyke gap in the northern Saemankeum area, 4 km wide between Yamido and Piungdo, has acted as an artificial tidal inlet. Due to such a changed geometry, tidal regime has been reversed from being flood- to ebb-dominated with a directional change from NE-SW to E-W. As a result, a large tongue-like tidal sand bar (named Saemankeum Bar) has conspicuously grown seaward through the artificial tidal inlet. The Saemankeum Bar composed of well-sorted very fine sands (3.0-3.5${\phi}$) has grown at a rate of 1.63 km/yr for the past three yews (1996-1998). Such a rapid growth of the sand bar is attributed to enhanced sediment supply derived from the degradation of former tidal sand bars at the mouth of the Mangyung River. Eventually the reworking of the tidal sand bars also caused the pre-existing tidal channels to be wider, deeper and more straightened. All of these phenomena well examplify the critical effect of artificial modifications on the natural estuarine environments.