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Black and Green Tea Supplements Ameliorate Male Infertility in a Murine Model of Obesity
Chunyang Han,Cuiyan Liu,Jiangsu Geng,Yun Tang,Yunsheng Li,Yijun Wang,Zhongwen Xie 한국식품영양과학회 2020 Journal of medicinal food Vol.23 No.12
Obesity, a chronic metabolic disorder, can affect male reproductive function. As a functional beverage, tea has many biological activities and potential in the treatment of obesity. However, its effects on male reproductive damage induced by obesity are not yet clear. In this study, a murine model of obesity was established by feeding with high-fat diet (HF). A total of 24 male mice were divided into four groups: normal diet (control), HF, HF supplemented with 5% green tea powder (HF+G), and HF supplemented with 5% black tea powder (HF+B). The results showed that the HF + B significantly reduced the mouse body weight gain and testicular coefficient and lowered the serum insulin and leptin levels compared with the HF group. The sperm malformation rate of mice in the HF group had a significant increase when compared with the control group, the HF + B group had a significant decrease compared with the HF group, and no difference from the control group. The HF + G and HF + B significantly increased testosterone levels in serum compared with the HF group. The testosterone production-related gene cytochrome P450 family 11 subfamily a member (CYP11A1) and cytochrome p450 family 17 subfamily a member 1 (CYP17A1) expressions in testis were significantly increased in the HF + G group compared with HF group. In addition, the HF + G and HF + B abolished the effects of HF on superoxide dismutase (SOD), malondialdehyde, and glutathione levels in testis and antioxidant-related gene expressions of XRCC1 and SOD1. Overall, our findings have provided evidence that black and green tea has a positive effect on reducing reproductive damage in a male murine model of obesity, and that black tea is more effective than green tea.
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Bert Breuer,Michael barz,Karlheinz Bill,Steffen Gruber,Martin Semsch,Thomas Strothjohann,Chunyang Xie 한국자동차공학회 2002 International journal of automotive technology Vol.3 No.2
Future on-board vehicle control systems can be further improved through new types of mechatronic systems. In particular, these systems' capacities for interaction enhance safety, comfort and economic viability. The Automotive Engineering Department (fzd) of Darmstadt University of Technology is engaged in research of the mechatronic vehicle corner, which consists of three subsystems: sensor tire, electrically actuated wheel brake and smart suspension. By intercommunication of these three systems, the brake controller receives direct, fast and permanent information about dynamic events in the tire contact area provided by the tire sensor as valuable control input. This allows to control operation conditions of each wheel brake. The information provided by the tire sensor for example helps to distinguish between straightline driving and cornering as well as to determine μ-split conditions. In conjunction with current information of dynamic wheel loads. tire pressures and friction tyre/road, the ideal brake force distribution can be achieved. Alike through integration of adaptive suspension bushings, elastokinematic behaviour and wheel positions can be adapted to manoeuver-oriented requirements.
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