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      • KCI등재후보

        Epithelioid Sarcoma in the Cervical Spine: A Case Report

        Chungnam Lee,최우진,Na Ra Kim 대한척추신경외과학회 2015 Neurospine Vol.12 No.3

        Epithelioid sarcoma is a rare and highly malignant soft tissue neoplasm that most commonly occurs in the long bones. This uncommon tumor has a poor clinical outcome, and the modality of its treatment has not yet been fully established. The authors report an extremely rare presentation of epithelioid sarcoma in the cervical spine, along with its clinical progression, imaging, and pathology. The patient underwent three surgical procedures and adjuvant radiochemical management. He survived for 25 months with a good general condition and adapted well to his social activity. Systemic metastasis was not found, but the patient died of respiratory failure due to direct tracheal invasion of the tumor.

      • Effect of Intra-operative Saline Irrigation during Burr Hole Surgery on the Recurrence for Chronic Subdural Hematomas

        Chungnam Lee,Dong Sun Park,송상우,Young Il Chun,조준,문창택,Young Cho Koh 대한말초신경학회 2015 The Nerve Vol.1 No.1

        Objective The aim of this study is to compare the postoperative recurrence rates and alteration in follow-up brain CT radiographic results between patients with chronic subdural hematoma (CSDH) treated by burr hole trephination with or without irrigation during the surgery. Methods A total of 100 patients diagnosed with CSDH underwent burr hole trephination from January 2013 to May 2015. The patients were divided into two groups: those who underwent intra-operative saline irrigation and those who did not. Difference in the rate of symptomatic recurrence requiring second surgery between the two groups was evaluated. Radiographic results were analyzed based on the patients’ follow-up brain CTs taken 1 month after the surgery. Results Sixty eight patients underwent intra-operative irrigation while 32 patients did not. The median ages of the two groups were 69.6 years (range, 39-91 years) and 69.1 years (range, 38-86 years), respectively. Among the “irrigated” group, six patients required second surgery due to recurrent hematoma (8.8%) while nine patients in the “not irrigated” group underwent second surgery (28.1%). Difference in the Glasgow coma scale (GCS) between the two groups had no statistical significance. Conclusion Upon conducting burr hole trephination surgery for CSDH, saline irrigation is a simple procedure that can reduce the recurrence rate

      • KCI등재

        Inhibitory effects of medicinal plants on elastase activity and biological activities in the active Plant extracts

        ( Lee K. K ),( Cho J. J ),( Choi J. D ),( Jeongchon-ri ),( Seonggeo-eup ),( Cheonan-si ),( Chungnam ) 대한화장품학회 1997 대한화장품학회지 Vol.23 No.2

        Inhibitory effects of 200 medicinal plants on elastase activity were screened. Among the 200 plants, six plant extracts exhibited more than 65% of inhibition on elastase activity by their total methanol extracts at 1, 000㎍/㎖ as a final concentration. For six active plants including Areca catechu(IC<sub>50</sub>:42.4 ㎍/㎖), Cinnamonum cassia(IC<sub>50</sub>:208.7 ㎍/㎖), Myristica frograns(lC<sub>50</sub>:284.1 ㎍/㎖), Curcumma longa(lC<sub>50</sub>:398.4 ㎍/㎖), Alponia katsumadai(lC<sub>50</sub>:465.7 ㎍/㎖), and Dryopteris crassirrhizoma(IC<sub>50</sub>:714.4 ㎍/㎖), the inhibitory effects of their comsituents were examined on the activity of human leukocyte elastase, hyaluronidase and lipid peroxidation. In lipid peroxidation assay using TBA method, three of the 6 plants including Curcumma longa(lC<sub>50</sub>:45.5 ㎍/㎖), Areca Catechu(lC<sub>50</sub>:51.0 ㎍/㎖) and Alponia katsumadai(lC<sub>50</sub>:116.3 ㎍/㎖) exhibited more than 70% of inhibition at the concentration of 1, 000㎍/㎖, but only one plant, Areca Ctechu(lC<sub>50</sub>:563 ㎍/㎖) showed high inhibitory effect on hyaluronidase activity. The results suggest that medicinal plants showing several biological activities may be potent inhibitors of anti-aging process on skin and that might be useful for application in cosmetics.

      • PRECEDE-PROCEDE 모형을 활용한 실업계 고등학생의 건강증진 프로그램 개발

        이화연(Lee, Hwa-Yean),김정남(Kim, Chungnam) 계명대학교 간호과학연구소 2010 계명간호과학 Vol.14 No.1

        Purpose: The purpose of this study was to develop the tailored health promotion program for vocational high school students through PRECEDE-PROCEDE process. Method: The data were collected from August 23rd to December 30th, 2004. The subjects of this study were the 10th graders in the D vocational high school in D city. On diagnostic stage, the total number(297) of 10th graders were participated. Result: The tailored health promotion program for vocational high school students was developed based on the diagnostic result using PRECEDE-PROCEED model (social, epidemiological, behavioral, environmental, educational, ecological and administrative, policy assessment). The contents of health education program were included growth and development of adolescence, improvement of self-esteem and communication skill, mental health for adolescent, family health, physical health for adolescent, prevention of school violence and ostracism, pregnancy and contraception, prevention of sex related problem and sexual violence, alcohol and health, understand human mind and control self anger, safety and accident prevention, computer game addiction and VDT syndrome, and stress management. The contents of smoking cessation program were included smoking cessation classes(preparation phase), art therapy(drawing poster, making clay ceramics, and making collagist), watching smoking cessation videos(resolution phase), experimental test by SMOKYⓇ doll and gold fish, discussion class after experimental test, a mock trial on smoking, role-playing, make a written pledge and swear on no smoking(practice phase). The exercise program was included jumping rope exercise and physical fitness exercise by using instruments which located in school physical training center. In addition, the students were required to perform a 30 minutes rope jumping exercise everyday at home. The health-counseling program was conducted based on self reported health behavior practice checklist. Positive reinforcement and encouragement counseling approach was used. When the students fail the practice, discussed the reasons and found the way how to solve the problems. This counseling program included the participation of the parents through the use of notes and letters sent to their homes. Conclusion: In conclusion, the health promotion program which developed by the researcher for vocational high school students was expected as an effective, working, and easily applicable intervention program for improving the vocational high school students' self-efficacy, self-esteem, health knowledge, health promoting behavior, health status, and life satisfaction level, and reducing harmful-unhealthy behavior, physical health problem, and mental health problem.

      • KCI등재
      • 일 보건소 호스피스ㆍ완화의료 사업을 위한 지역주민의 요구도 평가

        이병숙(Lee Byoungsook),고효정(Kho Hyojung),권영숙(Kwon Youngsook),김정남(Kim chungnam),곽혜원(Kwak Hyeweon),박미현(Park Mihyun) 계명대학교 간호과학연구소 2008 계명간호과학 Vol.12 No.1

          Purpose : The purpose of this study was to identify the perception about hospice and palliative program offered by Sungju-gun public health center and the needs for the hospice and palliative service in the residents of Sungju-gun. Method : The subjects of this study were 500 residents who were 20 years old and more. Data were collected from Aug. 6, 2007 to Aug. 31, 2007 with tools developed by researchers. Data were analyzed with SPSS/WIN 12.0 version. Results : Mean score of the perception about hospice and palliative program offered by Sungju-gun public health center was 8.45(SD 5.75) out of 19.00. There were significant difference in the score of the perception according to the subjects" age, monthly income, religion, education and marital status. In the needs for hospice and palliative service offered by Sungju-gun public health center, the score of the dimension "Service Connection" was highest, 1.75 out of 2.00, and the score of the item "Assistance for activities in daily living" in volunteer service was highest, 1.82 out of 2.00. There were significant difference in the score of the needs for hospice and palliative service according to the subjects" monthly income. Conclusion : The results showed the perception of the subjects about hospice and palliative program offered by Sungju-gun public health center was low while the perception of the subjects with old age, low income, and low education was relatively high. So, hospice and palliative service programs for these populations service connection and volunteer services are especially strengthened should be developed and actively informed to the residents.

      • Harmonic Analysis of Three-Phase Diode Rectifier and Measurement of Conducted EMI Emission Using LISN

        Y.M.Chae,G.H.Choe,H.S.Mok,E.W.Lee,S.C.Hong,S.H.Baek,Kon-Kuk,Seoul National Polytechnic Unv,ChungNam Unv,Dan-Kook Unv,Dong-guk Unv 전력전자학회 1995 ICPE(ISPE)논문집 Vol.1995 No.10

        Three phase diode rectifier are widely used in high power rating system because of simple structure and low cost. But AC spiky input current which has plentiful harmonics flows to the power line and cause low input power factor. So this paper represents harmonics analysis and characteristic analysis of. DPF, THD and PF of input current.<br/> And conducted EMI emission which can be measured using IISN(L. me Impedance Stabilization Network), is studied in case of three phase diode rectifier to investigate the behavior of Conducted EMI emission .

      • MOLECULAR GENETIC STUDIES OF KOREAN POPULATION : 6. Genetic Polymorphism and gene frequency of TPI, GPI and α_2 HSGP

        KIM, YUNG JIN,PAIK, SANG GI,LEE, CHUNG CHOO,AHN, GWANG SOOK,KIM, JONG SOON 충남대학교 기초과학연구소 1989 연구논문집 Vol.9 No.-

        In order to study the genetic characteristics of Korean population, 1,202 hemolysate samples were screened for TPI and GPI, and 505 serum samples were analysed for α_2 HSGP. Both of the genes controlling TPI and GPI were fixed at TPI*1 and GPI*1 alleles, respectively. However, α_2 HSGP was polymorphic and controlled by two alleles, α_2 HSGP*1 and α_2 HSGP*2 with the frequency of 0.7090 and 0.2910, respectively.

      • Expression Analysis of the Ligand to Ly-6E.1 Mouse Hematopoietic Stem Cell Antigen

        Hwang, Dae Youn,Min, Dullei,Sonn, Chung Hee,Chang, Mi Ra,Lee, Mi Hyun,Paik, Sang-Gi,Kim, Young Sang 충남대학교 생물공학연구소 1998 생물공학연구지 Vol.6 No.-

        Ly-6E.1 antigen was proposed as a regulatory molecule of T lymphocyte activation, a hematopoietic stem cell marker, a memory cell marker, and an adhesion molecule. Though there were several reports suggesting the presence of Ly-6 ligand, the characterization of the ligand was not yet performed. As an attempt to screen the expression of Ly-6E.1 ligand, we prepared a probe for detecting Ly-6E.1 ligand by producing a fusion protein between Ly-6E.1 and hlgC_r1. A mammalian cell expression vector with Ly-6E.1/hlgC_r1 chimeric cDNA was transfected in SP2/0-Ag14 myeloma cells, and stable transfectants were selected. The fusion protein was produced as a dimer and maintained the epitopes for monoclonal antibodies specific for Ly-6E.1 and for anti-human lgG antibody. The purified fusion protein through Gammabind G column was used for FACS analyses for the expression of Ly-6E.1 ligand. The fusion protein interacted with several cell lines originating from B cells, T cells, or monocytes. The fusion protein also strongly stained bone marrow, lymph node, and spleen cells, but thymic cells weakly, if any. The staining was more obvious in C57BL/6 (Ly-6^b) than Balb/c (Ly-6^a) mice. These results suggest that the interaction of Ly-6E.1 with Ly-6E.1 ligand may function both in the stem cell environment and in the activation of mature lymphocytes. The fusion protein may be a valuable tool in characterization of biochemical properties of the Ly-6E.1 ligand and, further, in isolating its cDNA.

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