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      • B형 간염바이러스의 태아와 성인간세포에 대한 감염성 해명 연구

        정태호,김성국,서화정,윤영국,임종완,차상호 경북대학교 의학연구소 1999 경북대학교병원의학연구소논문집 Vol.3 No.1

        사람의 태아와 성인의 간세포에 대한 B형 간염바이러스의 감염도를 비교 분석함으로써 HBV 와 간세포간의 친화도내지는 HBV 수용체에 관한 정보를 얻고자 함 대상 및 방법 : 성인이 외상을 입어 부득이 손상된 간조직을 절제하였을 경우와 모자보건법상 임신지속이 어려운 상태에서 부인과적 수술시 21주 전후의 태아 간조직을 얻어 DMEM 을 배지로 50% 용량으로 HBsAg 양성인 사람 혈청을 가하여 5일간 체외 배양하고 병리조직학적 처리후 효소 면역학적 방법으로 HBsAg 를 염색하여 바이러스의 존재 여부를 검색하였다. 결과 : 태아와 성인 간조직을 5일간 체외 배양하였을 때 그 조직상은 간조직임을 인지할 수 있었다. HBV 의 감염여부는 DAKO 사의 효소면역 법으로 조사한 결과 태아의 간조직에서는 HBsAg 양성부위를 발견하지 못하였으나, 성인 간조직에서는 HBsAg 양성부위가 발견되었다. 결론 : 태생 21주 전후의 태아의 간세포는 HBV 와 친화도는 아주 미약하거나 없고, 성인 간세포는 HBV에 대한 친화도가 높다. 따라서 태생 21주의 간세포에는 HBV 의 감염이 어렵다는 것을 인지하게 되었다. Considerable progress has been made in the immune prophylaxis of hepatitis B virus(HBV) infection and in the understanding of its replication and pathogenecity at the molecular level. However, a convenient in vitro assay for HBV infectivity has been lacking and the early steps of viral life cycle are now yet well understood. Primary cultured human hepatocytes are reported to be susceptible to HBV 10-12, but these systems are not practical because they are short-lived and require primary explanted human liver. However, it is uncertain yet whether primary hepatocytes of human fetal liver are susceptible to HBV for infection or not. We have expanded the infectivity of HBV into a primary cultures of human fetal hepatocytes together with controversy of adult primary hepatocytes. To investigate the infectivity of HBV for, adult and fetal hepatocytes After 5 day culturing fetal(1) and adult(2) liver tissues, which obtained from a surgical operation on DMEM culture media with half HBV positive serum, separating liver cells and fixing them, the existence of HBsAg antigen was investigated through the immuno-enzymatic staining. HBsAg stained area was not found in the 21 weeks gestation liver cells until 5 days of invitro-culture, while it was found in the adult liver cells. This test result showed that the HBV infection is very hard to happen in the liver cells 21 weeks gestation or prior one.

      • 동적 임계치를 이용한 ATM ABR 트래픽 제어의 성능 및 공정성 분석

        정영준,송화선 강원대학교 정보통신연구소 1997 정보통신논문지 Vol.1 No.-

        The rate control method for the Available Bit Rate(ABR) service classes has been developed in ATM Forums over Asynchronous Transfer Mode(ATM). This paper proposes a simulation model of ABR traffic controls based upon a highway merge model and dynamic thresholds for congestion control, to find the optimum parameter values and investigate their performance and fairness with the change of QBR traffic control parameters. Also in this paper, an ABR feedback control models such as FECN(Forward Explicit Congestion Notification), BECN(Backward Explicit Congestion Notification), and BP(Backpressure) with RM(Resource Management) based EPRCA has been analyzed and characterized.

      • 電壓源 인버터를 制御하기 위한 SHE PWM의 最適 스위칭 패턴

        鄭東和 순천대학교 공업기술연구소 1989 工業技術硏究所論文集 Vol.3 No.-

        本 硏究는 SHE(Selected Harmonic Elimination) PWM(Pulse Width Modulation)의 正確한 最適 스위칭패턴의 한 方式으로 CV(Constant Voltage)에서 HEB(Harmonic Elimination Band)를 定하여 이 HEB에 속하는 모든 解를 구한 다음, 이 解에 해당하는 GKF(Generalized Klirr Factor)를 計算하여 GKF가 最小가 되는 最適 스위칭패턴을 決定하였다. 이와같이 計算된 最適 스위칭패턴의 解를 NR(Newton―Raphson)法의 初期條件으로 하여 VV(Variable Voltage)의 스위칭패턴을 容易하게 決定할 수 있도록 하였다. 이러한 理論的 提案의 妥當性을 立證하기 위하여 PTR(Power Transistor)로 構成된 인버터를 設計하여 誘專電動機를 可變速 運轉시켜 보았으며 이 때 나타나는 結果들을 比較, 分析하여 提示하였다. This paper is proposed one method of the exat optimal switching patterm of Selected Harmonic Elimination (SHE) Pulse Width Modulation (PWM). It defined Harmonic Elimination Band (HEB) in Constant Voltage (CV) and sought all solutions which are included HEB. Then, it calculated Generalized Klirr Factor (GKF) belong to this solution and decided optimal switching pattern is minimized this GKF. This optimal switching solution is used as initial condition of Newton Raphson (NR) method to decided easily switching pattern at Variable Voltage (VV) To verify the validity of this theoretical proposition, It is designed inverter by power Transistor(PTR) and is implemented Variable Speed Drive (VSD) of Induction Motor (IM). This paper is proposed results which is comparison and analysis.

      • DCMU에 依한 보리 葉綠體의 色素 含量變化

        鄭華淑 慶北大學校 師範大學 1980 敎育硏究誌 Vol.22 No.-

        The present experiment was conducted to characterize the changes of pigment contents induced by DCMU. Chloroplasts from barley leaves (Hordeum vulgare L.) were incubated in the light and dark with DCMU for 24 hours. The most rapid loss of chlorophyll was observed in the chloroplasts incubated in light with 5μM DCMU. Similar results of Chlorophyll loss were also observed in DCMU-treated lamellae. The loss of total carotenoid was somewhat greater and more rapid than that of the chlorophyll in DCMU-treated chloroplasts and lamellae. Isoascorbate and DCIP provided complete protection against loss of chlorophyll and carotenoid. After illumination of DCMU-treated chloroplasts showed the greatest loss in the carotene, followed by chlorophyll a and xant-hophylls in a constant ratio and finally by chlorophyll b.

      • 정수장에서 SCUM의 발생원인과 제거방안

        정팔진,차화정,곽동희 全北大學校 附設 都市및環境硏究所 1995 都市 및 環境硏究 Vol.10 No.1

        This study was performed to present the removal method and occurrence cause of scum in water treatment plant of Chonju city. Because e scum generally involves foam and bubble, occurred scum in especially Jigok water treatment plant among the water treatment plants of Chonju city makes not only much difficulty for treatment, but also the problem of an aesthetic In the result, the cause of scum occurrence was happened by ABS components and occurred bubble. ABS results from the input of domestic and industrial waste water. It forms bubble on the water surface in the process of fall and coagulation, and forms scum on the water surface in the condition of capture and rise of coagulated floc. Daesung water treatment plant appeared ABS concentration of 0.25∼0.32ppm, where that of Jigok water treatment was 0.37∼0.42ppm. As the DO saturation rate to intake station and gauging well was investigated, and the retention time of water channel was considered, the air bubble was occurred by the separation of supersaturation DO because of the intake air. Therefore, the cause of scum generation was found to the air bubble mentioned above. So, it was required to minimize the air intaking at pump and pipe line.

      • 급성 심근경색증에 동반된 승모판 폐쇄부전증의 임상적 특징

        정상만,조영일,조화상,유광하,송기호,인행환 건국대학교 의과학연구소 1997 건국의과학학술지 Vol.7 No.-

        The early detection and proper management of mitral regurgitation(MR) associated with acute myocardial infarction(MI) is very important to improve the clinical course and outcome of disease. The change of left ventricular shape and regional function, papillary muscle rupture are major determinant of the existence and severity of MR. We performed 2D and M mode echocardiography of 28 patients at the early stage of acute MI to evaluate the existance and degree of MR and its pathogenetic factor. Significant MR occured in 12 (42.9%) patients. In the group of MI with MR, the inferior MI was frequent (7 case) than anterior MI (5 case) comparing to the patient group of MI without MR (inferior MI : 6 case, anterior MI : 10 case) (p<0.01).The left ventricular end diastolic dimension(LVEDD), end systolic dimension (LVESD) and left atrial dimension (LAD) were significantly increased in MI with MR than MI without MR (LVEDD : 57.3 ±8.6 vs 46.4 ±9.2, p<0.05 ; LVESD : 52.9 ±9.2 vs 38.3 ±7.4, p<0.01 ; LAD : 45.4 ±3.8 vs 37.7 ±3.7, p<0.05).However, the ejection fraction was not different between two group two groups. These datas showed that MR was more frequent in inferior MI and the hemodynamic derangement was more serious in acute MI with MR.

      • KCI등재

        이소매복된 하악 제2소구치의 자가치아이식을 이용한 치험례

        정윤주,궁화수,최성철,김광철,박재홍 大韓小兒齒科學會 2009 大韓小兒齒科學會誌 Vol.36 No.4

        악골내 이소매복된 치아로 인해 유치의 만기잔존, 교합이상과 같은 교정적인 문제가 발생할 경우 그 해결책으로 주기적 관찰, 최소한의 개입, 교정적 견인, 발치, 그리고 환자 자신의 매복치아를 이용하는 자가이식술 등을 들 수 있다. 자가치아이식은 치아를 구강내의 한 위치에서 다른 발치와나 외과적으로 형성된 치조와로 이동시키는 술식으로, 치아가 교정력을 가할 수 없는 위치에 존재하거나 치아 이동에 제한이 있어 통상적인 치료가 불가능할 경우에 발거에 앞서 고려할 수 있는 방법이다. 자가치아이식은 치료기간을 단축시키고, 치근 형성이 완료되지 않은 어린 환자의 경우 이식된 새로운 위치에서 치근 형성이 이루어지며, 새로운 치조골의 형성을 유도할 수 있다. 본 증례는 하악 우측 제2소구치의 매복과 하악 우측 제2유구치의 만기잔존을 주소로 본원에 내원한 11세 여아로, 하악 우측 제2소구치의 매복의 깊이가 깊고, 방향이 교정적 견인에 불리하다는 점, 미성숙 치근 발육 상태와, 만기잔존한 유구치로 인해 공간 상실이 없다는 점 등을 고려하여 자가치아이식을 시행한 뒤, 1년간의 주기적 관찰 결과, 양호한 결과를 얻어 이에 보고하는 바이다. In the case of the impacted teeth, the clinician has to consider development of tooth, site of impaction, eruption path, and cooperation of patient. Treatment options for the management of impacted teeth are separated into four categories: observation, intervention, orthodontic or surgical relocation and extraction. Autotransplantation may be defined as the transplantation of embedded, impacted or erupted teeth, from one site to another in the same individual into extraction site or surgically prepared sockets. Autotransplantation ensures preservation of natural tooth, induction of alveolar bone growth and root development, offers one of the fastest and most economically feasible means in the replacement of young patients' missing teeth. This case presents a malpositioned impacted mandibular premolar of an 11-year-old girl. It was thought that orthodontic traction was difficult because of its unfavorable impacted position. Therefore the tooth was treated by autotransplantation, we can observe good healing pattern during 12 months.

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