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      • 악안면골 골절에 관한 임상적 연구

        정호균 중앙대학교 의과대학 의과학연구소 1988 中央醫大誌 Vol.13 No.4

        This report was a retrospective study on maxillofacial bone fractures of Koreans. The study was based on a series 306 patients who had been treated for maxillofacial fractures as in-patient at Hospital of Medical college of Chung-Ang University during the pried of 1982 to 1987. The results obtained are as follows; 1. The ratio of Men to Women was 4.2:1, and the incidence of facial bone fractures increased continuously year after year. 2. The age frequency was highest in Tnd decade(38.3%), and age distribution of patient ranged from 4 years to 84 years. 3. Traffic accident(40.7%), fighting(28.5%) were the most common cause of maxillofacial bone fractures. 4. The frequent locations of maxillofacial fractures were nasal bone(49.4%) and followed by the mandible(22.2%), zygoma and zygomatic arch(16.6%) and maxilla(11.8%) in order. One location fractured in 88.1% and multiple locations were involved in 11.9%. 5. In 98 patients of mandible fractures, 85(86.7) had fractures only in mandible and 13(13.3%) had another facial bone fractures. The most frequent fracture site was Symphyseal area(37.4%) and simple fracture was the most frequent in type of fractures(43.9%). Teeth or alveolar bone trauma cases were 55.5% and close reduction with intermaxillary fixation was major method of treatment(43.9%) in mandible fractures. 6. In 52 patients of Maxillary fractures, 19(36.5%) had fractures only in maxilla and 33(63,5%) had another facial bone fractures. The most predominent fracture site was Le Fort Ⅱ(28.8%), and teeth or alveolar trauma occured in 25.0% and open reduction was major method of treatment(34.6%) in maxillary fractures. 7. In 73 patients of zygoma complex fractures, 41(56.2%) had fractures only in zygoma complex and 32(43.8%) had another facial bone fractures. The most frequent fracture site was zygoma(54.8%), and observation (47.9%) and open reduction(35.6% ) were major method of treatment in zygoma complex fractures. 8. In 218 patients of nasal bone fractures, 195(89.4%) had fractures only in nasal bone and 23(10.6%) had fractures on another facial bone. Closed reduction(55.5%) and observation(28.4%) were major methods of treatment. 9. In 386 patients of facial bone fractures, the most common associated injury with facial bone fractures was head(32.7%) and eye(20.4%) injures.

      • KCI등재

        항정신병 약물 비폭로, 치료 중 및 만성 시설화 정신분열증 환자에서의 연성 신경학적 징후의 비교

        채정호,이규항,백인호,이정균 大韓神經精神醫學會 1997 신경정신의학 Vol.36 No.2

        Objects : Many studies have demonstrated greater frequency of soft neurologic signs in patients with schizophrenia than in controls. However, factors associated with chronicity,institutionalization, individual differences and neuroleptic medication make it difficult to interpret these results. We report on our ongoing study of soft neurologic signs and their relationship to neuroleptics and institutionalization in schizophrenia. Methods : Soft neurologic signs were examined with a standardized instrument, Neurological Evaluation Scale- Korean Version(NES-K) in 11 neuroleptic-naive patients with schizophrenia, 17 neuroleptic-treated patients and 14 chronically institutionalized patients. Results : Scores of total items(p<0.05), sensory integration(p<0.05), sequencing of complex motor acts(p<0.05) and others(p<0.01) functional areas of NES-K were significantly different among three groups. There was no difference in the area of motor coordination. Posthoc analysis showed that scores of total items(p<0.005) and sensory integration areas(p<0.01) of NES-K were significantly higher in the institutionalized patients than those of neurolepticnaive group. However scores of sequencing of complex motor act and others categories were not different in the institutionalized and neuroleptic-naive patients. Conclusion : These findings suggested that neuroleptic treatment or chronic institutionalization might partially affect soft neurologic signs, especially sensory integration area, in patients with schizophrenia. However, the soft neurologic signs of motor coordination area could be a biological trait marker of schizophrenia independent of confounding variables.

      • KCI등재

        한 정신병원에서의 강박 처치에 대한 입원 환자 및 병원 직원의 지각의 차이

        채정호,차성조,함웅,이규항,이정균 大韓神經精神醫學會 1996 신경정신의학 Vol.35 No.5

        한 정신병원에서 강박처치의 적응증, 합병증, 대체법, 감정적 영향, 적당한 처치 시간, 처치의 효능과 필요성등을 병원에 입원 중인 환자들과 직원들에게 설문조사를 하여 양 집단간에 차이가 있는 지를 알아봄으로써 환자들과 직원들간에 있는 강박처치에 대한 지각 차이를 조사하고 나아가 강박처치 시행의 규준을 확립하기 위한 기본 자를 제시하기 위하여 본 연구를 시행하였다. 강박처치의 적응증에 대해서 입원환자들은 대부분의 항목에 대해 부정적으로 보았고 단지 타환자에 대한 신체적 공격에 대해서만 다소 긍정적인 반응을 보인 반면 직원들의 경우 자해, 타환자에 대한 신체적 공격, 치료진에 대한 공격 등에 높은 응답율을 보였다. 강박처치의 부작용에 대한 지각은 입원환자의 경우 정신상태의 악화, 자해의 증가 등에 대해 보다 민감하게 반응 하였고, 실제로 경험한 부작용에 있어서는 직원들의 경우 피부박탈을 더 강조한 반면 환자군에서는 호흡곤란, 정신 상태의 악화 등을 강조하였다. 강제 처치에 대한 대체치료 방법으로는 환자군에서 면담을 중요시한 반면 직원군에서는 격리실의 이용을 강조하였다. 신체억제와 고용량의 정온화를 비교한 것은 환자군에서 신체억제가 더 효과적이라고 하였다. 신체억제 동안 느끼는 감정에 대한 지각에서 환자군은 슬픔을 가장 많이 보고하였고, 직원군은 적개심을 가장 많이 느낄 것으로 추정하였다. 신체억제의 시간에 대해서는 환자군이 긴 것으로 지각하고 있으며, 이상적인 신체억제의 시간은 환자군이 짧은 것이 좋다고 생각하고 있었다. 본 연구 결과 정신과 입원환자들과 병원직원들은 강박처치에 대하여 유의한 지각의 차이가 있다는 것을 알았으며 정신병원내에서 강제처치를 실시할 때에는 명확한 강박처치 시행에 대한 규준에 따라야 할 것임을 확인할 수 있었다. Objectives : The purpose of this study was to examine different perceptions of physical restraint and their nature between psychiatric inpatients and hospital staffs in a mental hospital and to provide baseline data for establishing the practicing standard of this therapeutic maneuver. Methods : Two hundred and two psychiatric inpatients who experienced physical restraint and 103 hospital staffs who frequently used this maneurer were surveyed with a questionnaire regarding indications, complications, alternative methods, emotional influences, duration of treatment and subjective effects of restraint. Results : Regarding indications of physical restraint, the inpatient group had negative viewpoint on the most items except "physical assault to other patients". Regarding the perception about possible complications of this treatment, the inpatient group had more concerns about "deterioration of mental status" and "increasing risk of self-injury". For experienced complications, staffs stressed "skin abrasion " while inpatients believed of "respiratory difficulties" and "deterioration of mental status" more frequently. As alternative methods of physical restraint, "increasing frequency of interview" was suggested by the inpatient group and "using seclusion room" was favored by the staff group. The inpatient group had an impression that physical restraint was more effective than high-dose neuroleptic tranquilization. For suspected emotion during this procedure, the inpatient group reported "sorrow" most frequently while the staff group presumed that "hostility" might be most frequent. Inpatients estimated that the average duration of physical restraint was longer than staffs did. Ideal duration of physical restraint was shorter in the inpatient group. Conclusion : These results suggest that there are definite differences in the perception of physical restraint between psychiatric inpatients and hospital staffs. Formal practing guideline for restraint should be set up with careful attention for these differences to maximize the therapeutic effect of this maneuver.

      • KCI등재
      • KCI등재
      • SCIESCOPUSKCI등재

        Changes of Creatine Phosphokinase Activities in Serum and Thoracie Duct Lymph Durig Hemorrhagic Shock in Dogs

        정태호,곽준식,김장균 생화학분자생물학회 1985 BMB Reports Vol.11 No.4

        The purpose of this study was to investigate the change of the activity of creative phosphukinase ;EC 2.7.3.2), glutamic oxaloacetic transaminase (EC 2.6.1.1) ana glutamic pyruvic transaminase (EC 2.6.1.2) of serum and thoracic duct lymph in dogs induced hetnocrhagic shock with the blood pressure maintained at 60mmHg. for 4 hours. The serum and thoracic duct lymph creative phosphokinase activities were found similarly increased in both sham (6 animals) and hemorrhagic shock (8 animals) induced groups following hemorrhage. But the increased level was less significant in sham operation dogs. The activities of serum a11d thoracic duct lymph transaminase were significantly increased Due to narrowness between tumor effective dose and toxic dose, there appeared a variety of dose of BCNU to be used in cancer. It was an annoying problem that the seemingly optimal dose in one patient would sometimes induce serious side effects. This study was carried out to determine the efficacy of lower dose of BCNU with immunotherapeutic agent tubercin-3, tuberculoprotein complex, extracted from human type Mycobacterium tuberculosis in Ehlich ascited mice. Sixty tumor-bearing mice were divided into 6 groups; 10 animals in each group receiving saline, tubercin-3, 2㎎ or 4㎎ per ㎏ body weight of BCNU, and 2㎎, and 4㎎ per ㎏ body weight of BCNU combined with tubercin-3, respectively in each time. Treatment was started 24 hours after tumor cell implantation and every other day for six times. The tubercin-3 was administered subcutaneously and BC NU intraperitoneally. After treatment began, the animal condition was observed daily two times and the time of death was recorded for life expectation of mice. The average increases of animal life span of each group were respectively as follows. Control is 13.8 days; tubercin-3 administration, 27.8 days; 2㎎ per ㎏ body weight BCNU, 36.4 days; 4㎎ per ㎏ body weight BCNU, 38.6 days; 2㎎ BCNU with tubercin-3, 42.6 days; and 4㎎ BCNU with tubercin-3, 43.5 days. Conclusively, the therapeutic potentiation is reflected to be extened life span in combined treatment of tubercin-3 and BCNU then none combine3 and it was also noticed that the low dose of BCNU could extend the life of Ehrlich ascites cancer-bearing mice when administered in combination with tubercin-3.

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