http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Yoo, Yoonjeong,Oh, Hyemin,Lee, Yewon,Sung, Miseon,Hwang, Jeongeun,Zhao, Ziwei,Park, Sunho,Choi, Changsun,Yoon, Yohan The Korean Society of Fisheries and Aquatic Scienc 2022 Fisheries and Aquatic Sciences Vol.25 No.5
The objective of this study was to evaluate the probability of norovirus foodborne illness by raw oyster consumption. One hundred fifty-six oyster samples were collected to examine the norovirus prevalence. The oyster samples were inoculated with murine norovirus and stored at 4℃-25℃. A plaque assay determined norovirus titers. The norovirus titers were fitted with the Baranyi model to calculate shoulder period (h) and death rate (Log PFU/g/h). These kinetic parameters were fitted to a polynomial model as a function of temperature. Distribution temperature and time were surveyed, and consumption data were surveyed. A dose-response model was also searched through literature. The simulation model was prepared with these data in @RISK to estimate the probability of norovirus foodborne. One sample of 156 samples was norovirus positive. Thus, the initial contamination level was estimated by the Beta distribution (2, 156), and the level was -5.3 Log PFU/g. The developed predictive models showed that the norovirus titers decreased in oysters under the storage conditions simulated with the Uniform distribution (0.325, 1.643) for time and the Pert distribution (10, 18, 25) for temperature. Consumption ratio of raw oyster was 0.98%, and average consumption amount was 1.82 g, calculated by the Pert distribution [Pert {1.8200, 1.8200, 335.30, Truncate (0, 236.8)}]. <sub>1</sub>F<sub>1</sub> hypergeometric dose-response model [1 - (1 + 2.55 × 10<sup>-3</sup> × dose)<sup>-0.086</sup>] was appropriate to evaluate dose-response. The simulation showed that the probability of norovirus foodborne illness by raw oyster consumption was 5.90 × 10<sup>-10</sup> per person per day. The annual socioeconomic cost of consuming raw oysters contaminated with norovirus was not very high.
Dual Imaging-Guided Oxidative-Photothermal Combination Anticancer Therapeutics
Noh, Joungyoun,Jung, Eunkyeong,Yoo, Donghyuck,Kang, Changsun,Kim, Chunho,Park, Sangjun,Khang, Gilson,Lee, Dongwon American Chemical Society 2018 ACS APPLIED MATERIALS & INTERFACES Vol.10 No.47
<P>Heme oxygenase-1 (HO-1) is a stress-response protein with potent cytoprotective and antioxidant activity, and its expression in cancer cells is enhanced in response to chemotherapy and radiotherapy. HO-1 is known to serve as a shield to protect cancer cells from anticancer therapy and attenuate apoptotic signals. It can be therefore reasoned that inhibition of HO-1 reduces the antioxidant level, making cancer cells more sensitive to photothermal heating. In this work, we developed dual imaging-guided oxidative-photothermal combination nanotherapeutics (OPCN) consisting of amphiphilic polymers conjugated with zinc protoporphyrin as a HO-1 inhibitor and fluorescent IR820 as a photothermal agent. A combination of OPCN and near-infrared (NIR) laser irradiation markedly increased the temperature and exerted significant toxicity through induction of apoptosis. In a mouse model of xenografts, tumors were identified by the strong fluorescence and photoacoustic signals. OPCN combined with NIR laser irradiation resulted in effective and complete thermal ablation of tumors without discernable side effects and tumor recurrence. We believe that OPCN hold tremendous translational potential for dual imaging-guided oxidative-photothermal combination anticancer therapy.</P> [FIG OMISSION]</BR>
박우철(Park Woochol),유병선(Yoo Byoungseon),김창선(Kim Changsun) 대한전기학회 2006 대한전기학회 학술대회 논문집 Vol.2006 No.7
준공진형 플라이백 컨버터를 사용하여 Full HD급 DLP 프로젝터용 컨버터 설계에 대해 고찰하였다. 소형 경량화 시키기 위한 방법으로 Full Mode Packaging 형태로 절연설계에 유리하게 하였고, Shidegn사의 MR4040을 사용하여 부분공진 스위칭 동작에 의해 고효율 저노이즈를 실현하였다. 중부하 시 스위칭 주파수는 35㎑, 경부하시 스위칭 주파수는 최대 200㎑이고 입력전압 AC 90~264[v], 출력전력 66W급의 컨버터을 제작하였으며 측정된 효율은 최고 93% 이다.