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Effect of Partially Purified Lipid from the Mussel Mytilus coruscus on Apoptosis in Cancer Cells
( You Jin Jeon ),( Jae Hyun Jeong ),( Yong Tae Kim ),( Seung Jae Lee ),( Eun Kyung Kim ),( Pyo Jam Park ),( Byong Tae Jeon ),( Sang Ho Moon ),( Chang Bum Ahn ),( Hyun Kang ),( Yon Suk Kim ) 한국응용생명화학회 2011 Applied Biological Chemistry (Appl Biol Chem) Vol.54 No.1
Anticancer effects of the mussel (Mytilus coruscus) cultivated in Korea were determined. Lipid extracts of Mytilus coruscus were prepared using extractions in several organic solvents: methanol, chloroform, hexane, methanol:chloroform=1:1, and chloroform:hexane=1:1. Anticancer activities of the extracts were evaluated using apoptosis assays analyzed by flow cytometry. The hexane extract exhibited the highest anticancer activity. This extract was further separated and purified using thin layer chromatography, through which lipid compounds were isolated, and their components were analyzed; the major fatty acids were eiocosadienoic acid (EA, C20:2), eicosapentaenoic acid (EPA, C20:5), and docosahexaenoic acid (DHA, C22:6), and these components were higher than those of the mussels cultivated in New Zealand and Italy. The partially purified lipid compounds exhibited an anticancer effect in several cancer cell lines. These results indicate that lipid extract of M. coruscus effectively inhibits in vitro tumor growth by inducing apoptosis of cancer cells.
Poster Display : Pathogenicity of Korean Winter Dysentery (WD) Bovine Coronavirus to Calves
( Jae Ho Jeong ),( Gye Yeop Kim ),( Soon Seek Yoon ),( Su Jin Park ),( You Jung Kim ),( Chang Min Sung ),( Sung Shik Shin ),( Bong Ju Lee ),( Hong Bum Koh ),( Chai Yong Lee ),( Nam Yong Park ),( Mun I 한국수의병리학회 2004 학술대회 Vol.8 No.-
Poster Display : Pathogenicity of Korean Winter Dysentery (WD) Bovine Coronavirus to Calves
( Jae Ho Jeong ),( Gye Yeop Kim ),( Soon Seek Yoon ),( Su Jin Park ),( You Jung Kim ),( Chang Min Sung ),( Sung Shik Shin ),( Bong Ju Lee ),( Hong Bum Koh ),( Chai Yong Lee ),( Nam Yong Park ),( Mun I 한국수의병리학회 2004 학술대회 Vol.2 No.-
Lasing in hybrid metal-Bragg nanocavities.
You, Jong-Bum,Kwon, Kyungmook,Lee, Wook-Jae,Shim, Jaeho,Won, Dongshik,Jung, Youngho,Park, Byounghun,Yu, Kyoungsik Optical Society of America 2013 Optics letters Vol.38 No.10
<P>We report room-temperature lasing from an optically pumped subwavelength-scale cylindrical InGaAsP pillar surrounded by circular Bragg reflectors on a metal substrate with a dielectric spacer layer. By taking advantage of wide in-plane photonic bandgaps and proper vertical antiresonances, three dielectric Bragg pairs produce a sufficient optical feedback capable of low threshold lasing from the fundamental TE011 mode. A large spontaneous emission coupling into the lasing mode is obtained from the cavity-enhanced Purcell effects and effective suppression of nonlasing modes.</P>