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- 저자 : Botao Ma (검색결과 2 건)
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WenJing Xiao,Jun Hou,Jie Ma,BoTao Yu,JianDong Ren,WeiHua Jin,Juan Wu,DeZhi Zheng,KaiHua Fan 대한약학회 2021 Archives of Pharmacal Research Vol.44 No.8
Mangiferin is a promising effective chemopreventiveagent against various tumors. However, itsclinical use is limited by poor water solubility and lowbioavailability. In this article, mangiferin loaded magneticPCEC microspheres (MG-MS) were designed, characterizedand the antitumor activity of MG-MS was evaluatedin vitro. The magnetic nanoparticles (MNP) were synthesizedvia the high-temperature reaction of ironacetylacetonate in phenyl ether in the presence of oleic acidand oleylamine. Poly (ε-caprolactone)-poly (ethyleneglycol)-poly (ε-caprolactone) (PCL-PEG-PCL, PCEC)copolymers were formed by ring-opening copolymerizationof ε-CL initiated by PEG-diol using Sn(Oct)2 as acatalyst and MG-MS were prepared by solvent diffusionmethod. MNP, PCEC copolymer, and MG-MS werecharacterized by GPC, TEM, XRD, FT-IR, 1H-NMP andMalvern Laser Particle Sizer. Meanwhile, the antiproliferativeactivity in vitro and in vitro release behavior of thismicrospheres were studied in detail. The results indicatethat the obtained magnetic microspheres might have greatpotential as an effective carrier for mangiferin used incancer chemotherapy.
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Performance study on the whole vibration process of a museum induced by metro
Weiguo Yang,Meng Wang,Jianquan Shi,Jiaqi Ge,Nan Zhang,Botao Ma 국제구조공학회 2015 Structural Engineering and Mechanics, An Int'l Jou Vol.55 No.2
The vibrations caused by metro operation propagate through surrounding soil, further induce secondary vibrations of the nearby underground structures and adjacent buildings. In order to investigate the effects of vibrations caused by metro on use performance of buildings, vibration experiment of Chengdu museum was carried out firstly. Then, the coupling tunnel-soil-structure finite element model was established with software ANSYS detailedly, providing a useful tool for investigating the vibration performances of structures. Furthermore, the dynamic responses and vibration predictions of museum building were obtained respectively by the whole process time-domain analysis and frequency-domain analysis, which were compared with the vibration reference values of museum. Quantitative analyses of the museum building performance were carried out, and the possible tendency and changing laws of vibration level with floors were proposed. Finally, the related vibration isolation measures were compared and discussed. The tests and analysis results show that: The vertical vibration responses almost increased with the increasing of building floors, while weak floors existed for the curve of horizontal vibration; The vertical vibrations were larger than the horizontal vibrations, indicating the vibration performances of building caused by metro were characterized with vertical vibrations; The frequencies of the museum corresponding to the peak vibration levels were around 6~17Hz; The damping effect of structure with 33m-span cantilever on vertical vibration was obvious, however, the damping effect of structure with foundation vibration isolators was not obvious.
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