Adhesive Properties, Extracellular Protein Production, and Metabolism in the Lactobacillus rhamnosus GG Strain when Grown in the Presence of Mucin

( Borja Sanchez ),( Naima Saad ),( Jean Marie Schmitter ),( Philippe Bressollier ),( Maria C. Urdaci ) 한국미생물 · 생명공학회 2010 Journal of microbiology and biotechnology Vol.20 No.6

Effects of Feeding Licury (Syagrus coronate) Cake to Growing Goats

Borja, M.S.,Oliveira, R.L.,Ribeiro, C.V.D.M.,Bagaldo, A.R.,Carvalho, G.G.P.,Silva, T.M.,Lima, L.S.,Barbosa, L.P. Asian Australasian Association of Animal Productio 2010 Animal Bioscience Vol.23 No.11

The objectives of this study were to determine the highest inclusion of licury (Syagrus coronate) cake in the diet of growing Boer goats without adverse effects on intake and digestibility and to determine its effects on ingestive behavior and physiological responses. Twenty entire, one year old 3/4 Boer goats, 18.1 kg (DS = 2.2) average body weight (BW), were allocated to dietary treatments in a completely randomized design. Each animal was confined in a $1.0\;m^2$ pen with a suspended floor and given ad libitum access to clean, fresh water. Diets were formulated to meet NRC (2007) requirements and the ingredients were: 50% of Tifton-85 (Cynodon sp.) hay, corn meal, soybean meal, mineral and vitamin premix, and licury cake. The treatments were: i) no addition of licury cake to the diet, ii) 15% (DM basis) addition of licury cake, iii) 30% licury cake and, iv) 45% licury cake. The experiment lasted for 17 days; the first 10 days were used to adapt the animals to the diets and facilities. The inclusion of licury cake increased the fiber concentration of the diets; however, there was no effect on either dry matter (DM) or organic matter (OM) intake. There was a linear increase (p<0.05) in the EE content of the diet as the addition of licury cake increased; however, EE intake did not differ (p>0.05) between treatments. The digestibility of non-fibrous carbohydrates (NFC) decreased with increasing inclusion of licury cake, as did NFC intake. The efficiency of ingestion of DM and NDF presented a negative quadratic effect with the inclusion of licury cake. Results from this study indicate that licury cake can be fed to goats at up to 45% of the diet without adverse effects on either intake or digestibility.

The influence of climate change on irrigation water requirements for corn in the coastal region of Ecuador

Borja, N. s.,Cho, J.,Choi, K. S. SPRINGER SCIENCE + BUSINESS MEDIA 2017 Paddy and water environment Vol.15 No.1

<P>This study investigated the irrigation water requirements (IWR) for corn in five provinces of the coastal region of Ecuador that have been influenced by climate change. The weather data were statistically downscaled from six General Circulation Models and compared with the current climate period from 1986 to 2012. CROPWAT 8.0 was used to estimate future IWR for corn cultivation from 2011 to 2100 based on the Representative Concentration Pathways 4.5 and 8.5 scenarios. Also the frequency of predicted rainfall for future periods was analysed to identify the possibility of obtaining the amount of water required for corn plantation from rainfall. The projected trend of future climate showed increases in temperature and rainfall. The predicted IWR showed a decreasing trend in the rainy season and a similar or slightly lower trend in the dry season. Sufficient rain for corn cultivation was predicted for the wet region of the study area, with lower IWR, whereas most of the dry region was shown to have similar patterns of current water demands, except an increase in predicted rainfall resulted in lower IWR in some parts of this region.</P>

Review Article : Current Evidence for Spinal Opioid Selection in Postoperative Pain

( Borja Mugabure Bujedo ) 대한통증학회 2014 The Korean Journal of Pain Vol.27 No.3

Background: Spinal opioid administration is an excellent option to separate the desirable analgesic effects of opioids from their expected dose-limiting side effects to improve postoperative analgesia. Therefore, physicians must better identify either specific opioids or adequate doses and routes of administration that result in a mainly spinal site of action rather than a cerebral analgesic one. Methods: The purpose of this topical review is to describe current available clinical evidence to determine what opioids reach high enough concentrations to produce spinally selective analgesia when given by epidural or intrathecal routes and also to make recommendations regarding their rational and safety use for the best management of postoperative pain. To this end, a search of Medline/Embase was conducted to identify all articles published up to December 2013 on this topic. Results: Recent advances in spinal opioid bioavailability, based on both animals and humans trials support the theory that spinal opioid bioavailability is inversely proportional to the drug lipid solubility, which is higher in hydrophilic opioids like morphine, diamorphine and hydromorphone than lipophilic ones like alfentanil, fentanyl and sufentanil. Conclusions: Results obtained from meta-analyses of RTCs is considered to be the ‘highest’ level and support their use. However, it´s a fact that meta-analyses based on studies about treatment of postoperative pain should explore clinical surgery heterogeneity to improve patient`s outcome. This observation forces physicians to use of a specific procedure surgical-based practical guideline. A vigilance protocol is also needed to achieve a good postoperative analgesia in terms of efficacy and security.

Poster Session : PS 0284 ; Gastroenterology : Ceftriaxone-Induced Neutropenia and Transaminitis : A Rare Idiosyncratic Reaction

( Annamarie Borja ),( Ivan Declarador ),( Veerendra Chadachan ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

Background: Neutropenia is a recognized, although a rare side effect of ceftriaxone. In clinical trials of ceftriaxone, neutropenia was mostly observed with prolonged (more than 4 weeks) treatment. We report here a patient who developed neutropenia and transaminitis within 3 days of starting ceftriaxone. We will also review here the literature on ceftriaxone-induced neutropenia and discuss the various mecha Methods: A 48-year old Chinese female was admitted for intermittent abdominal pain associated with fever and vomiting of nonbilous and nonbloody content. Her past medical history included that of a previous episode of UTI, which was treated with ceftriaxone. Physical examination was unremarkable except for mild epigastric tenderness. Results: Investigations revealed she had neutrophilic leucocytosis and the urine microscopy revealed pyuria. She was treated for UTI with intravenous Ceftriaxone. Serial laboratory showed the development of neutropenia and transaminitis after starting Ceftriaxone. Ceftriaxone was then withheld and marked improvement of the total white cell count and transaminases was noted. Conclusions: In the case presented, looking at the temporal profi le of the patient`s results, her neutropenia and transaminitis are likely ceftriaxone-induced. The development of transaminitis and neutropenia within 3 days of ceftriaxone use is likely due to the fact that the patient has already been sensitized from prior exposure to ceftriaxone during her previous admission for UTI. This case illustrates that the treating physicians should be aware of this rare but a serious potential idiosyncratic complication arising from the use of parenteral ceftriaxone in the community.

Current Evidence for Spinal Opioid Selection in Postoperative Pain

Bujedo, Borja Mugabure The Korean Pain Society 2014 The Korean Journal of Pain Vol.27 No.3

Background: Spinal opioid administration is an excellent option to separate the desirable analgesic effects of opioids from their expected dose-limiting side effects to improve postoperative analgesia. Therefore, physicians must better identify either specific opioids or adequate doses and routes of administration that result in a mainly spinal site of action rather than a cerebral analgesic one. Methods: The purpose of this topical review is to describe current available clinical evidence to determine what opioids reach high enough concentrations to produce spinally selective analgesia when given by epidural or intrathecal routes and also to make recommendations regarding their rational and safety use for the best management of postoperative pain. To this end, a search of Medline/Embase was conducted to identify all articles published up to December 2013 on this topic. Results: Recent advances in spinal opioid bioavailability, based on both animals and humans trials support the theory that spinal opioid bioavailability is inversely proportional to the drug lipid solubility, which is higher in hydrophilic opioids like morphine, diamorphine and hydromorphone than lipophilic ones like alfentanil, fentanyl and sufentanil. Conclusions: Results obtained from meta-analyses of RTCs is considered to be the 'highest' level and support their use. However, it's a fact that meta-analyses based on studies about treatment of postoperative pain should explore clinical surgery heterogeneity to improve patient's outcome. This observation forces physicians to use of a specific procedure surgical-based practical guideline. A vigilance protocol is also needed to achieve a good postoperative analgesia in terms of efficacy and security.

Prediction of Water Requirement for Corn in the Coastal Region of Ecuador

( Nicolas Borja ),( Jaepil Cho ),( Kyungsook Choi ) 한국농공학회 2015 한국농공학회 학술대회초록집 Vol.2015 No.-

The impacts of future climate change in crop water requirement (CWR) for corn were investigated in 5 provinces of the coastal region of Ecuador, which presents rainy (winter) and dry (summer) seasons with two climatological regions including wet and dry regions. Weather data from 1986 to 2012 was extracted and adopted as the base line for the study area. The Representative Concentration Pathways 4.5 and 8.5 scenarios were selected for this study, and 6 Global Climate Model (GCM) selected were downscaled and bias-corrected to predict three future periods of 2025s, 2055s, and 2085s. CROPWAT 8.0 was implemented to estimate the present and future CWR for corn growth. The projected climate showed an increase trend of temperature and rainfall under the RCPs scenarios for three time series. Due to the changes in rainfall and temperature, decreasing CWR in rainy season due to the increment in rainfall was shown while the dry season would have similar pattern of current water demand except some parts of this area showing less water requirement due to increase of rainfall. Since the climate change could affect to corn growth, appropriate measurements should be applied based on the predicted CRW to adapt climate changes.

Proposal for Microwave Boson Sampling

Peropadre, Borja,Guerreschi, Gian Giacomo,Huh, Joonsuk,Aspuru-Guzik, Alá,n American Physical Society 2016 Physical Review Letters Vol.117 No.14

Bioethanol Production by Mixed Culture of Saccharomyces Cerevisiae and Pachysolen Tannophilus

Josephine BORJA,Jimmie Neil KANG,Joseph AURESENIA 한국생물공학회 2017 한국생물공학회 학술대회 Vol.2017 No.4

Management and Marketing of Cultural Tourism in Spain

Luis de Borja Solé,Anne Zanatta 세계문화관광학회 2006 Conference Proceedings Vol.7 No.0

In light of WTO predictions for continued growth in world tourism and new trends in the tourism sector, Spain must look at and improve its existing offer of traditional sun and beach tourism to include an improved and more developed offer of cultural attractions and products. This implies careful planning and implementation of strategies and actions which will appeal to the growing number of cultural tourists attracted to various cities and areas around the country due to the growing number of low-cost airlines opening new routes between major and lesser known cities and the political, economic and socio-cultural changes occurring in Europe.