도시 및 농어촌 지역 거주 청중년 여성 1인가구의 건강수준 특성 비교 연구

김보람 ( Kim¸ Boram ),이경수 ( Lee¸ Kyung-soo ),정미영 ( Jung¸ Mi-yeong ) 한국도서(섬)학회 2021 韓國島嶼硏究 Vol.33 No.3

최근 부부와 자녀 중심으로 이루어진 가구 형태는 감소하고 1인가구가 급속하게 증가하고 있다. 1인가구는 라이프 스타일, 삶의 변화 등은 건강에 영향을 미치는 요인 중의 하나이다. 1인가구는 음주, 흡연, 비만 등의 건강생활행태에 있어 다인가구에 비해 상대적으로 위험성이 높은 집단으로 양극화, 고령화, 여성화의 특성을 가진다. 그러므로 이들은 신 건강취약계층으로 건강 사각지대에 놓일 가능성이 높아 향후 이들에 대한 사회경제적 비용이 점차 증가하게 될 것으로 예측하고 있다. 특히 여성 1인가구의 증가는 여성의 빈곤화를 초래할 수 있어 본 연구는 여성 1인가구를 대상으로 농어촌과 도시지역에 따른 두 집단 간의 건강특성을 분석하고자 하였다. 본 연구는 우리나라 청장년층 1인가구 여성들을 대상으로 이들의 건강한 삶에 영향을 주는 요인을 파악하기 위해 질병관리청으로부터 제공받은 2019년 지역사회 건강조사 원시자료를 활용하였다. 연구에 활용된 변수는 사회인구학적 특성, 건강수준 및 건강행태, 의료 이용, 정신건강, 사회적 연결망 및 사회활동 참여를 바탕으로 여성 1인가구의 거주지역에 따른 도시와 농어촌 두 집단 간 비교, 분석을 실시하였다. 여성 1인가구의 건강행태 및 수준을 보면, 청년은 생애주기 중 가장 건강한 시기이므로 농어촌과 도시 간 건강수준에 있어서 유의미한 차이를 보이지 않았으나, 중년의 경우, 주관적 불건강인지율(p<.001), 높은 현재흡연율(p=.013)과 고위험음주율(p=.038)의 불건강행태가 도시에서 높았고, 농어촌은 비만율(p<.001), 아침식사(주5-7회) 비율이 높았다(p=.009). 정신건강은 청년(p=.567)과 중년(p=.149) 모두 도시와 농어촌 두 집단간 스트레스 인지율의 유의미한 차이는 없었으나 우울감 경험율은 청년(p<.001)과 중년(p<.001) 모두 도시가 농어촌보다 높았고 유의미한 차이를 보였다. 사회적연결망 및 참여는 청년의 경우 농어촌이 친척(p<.001), 이웃(p<.001)과의 만남이 도시 보다 유의미하게 높게 나타났고, 사회활동은 친목활동(p=.040), 여가레저활동(p=.036), 자선단체 활동(p<.001)이 농어촌에 비해 도시가 더 활발하였다. 중년의 경우, 친척(p<.001), 이웃(p<.001)과의 만남이 농어촌이 도시보다 유의미하게 높게 나타났고, 사회활동은 종교활동(p=.102), 여가레저활동(p=.145)은 도시에서 높았던 반면 친목활동(p=.381)과 자선단체활동(p=.364)은 농어촌에서 높았으나 유의미한 차이는 없었다. 그 동안 노인 여성 1인가구를 중심으로 이루어진 연구가 많이 이루어져왔던 반면 청중년 여성 1인가구를 바탕으로 한 건강연구는 많이 이루어지고 있지 않았다는 점에서 본 연구의 의의가 있다. 따라서 본 연구결과는 청중년 여성 1인가구의 특성을 분석한 기초자료를 제공하며, 이들의 건강증진 및 유지를 위한 제언을 제시하고자 하였다. Recently, the number of households centered on couples and children has decreased and the number of single-person households has increased rapidly. Single-person households are one of the factors that affect health, such as lifestyle and life changes. Single-person households have the characteristics of polarization, aging, and feminization compared to multi-person households, so single-person households are likely to be in a health blind spot as one of a set of newly identified health vulnerable groups. Among them, the purpose is to analyze the health characteristics between the two main groups according to urban, farming, and fishing areas, especially focusing on single female households. According to the health behavior and level of single-woman households, young people showed no significant difference in health level among urban, farming, and fishing areas, because it is the healthiest time of their lives, but in middle age, subjective poor self-rated health(p<.001), high current smoking rates(p=.013) and high risk drinking rates(p=.038) was high in cities, and farming and fishing areas had an obesity rate of(p<.001), while breakfast consumption(5-7 times a week) rates were high(p=.009). Mental health in young people is(p=.567) and in middle-aged people recorded at(p=.149) There was no significant difference in stress recognition rates among urban, farming, and fishing areas, but both young people(p<.001) and middle-aged folk(p<.001) showed significant differences as cities were higher statistically than farming and fishing areas. Social networks and participation are related to young people in farming and fishing areas(p<.001) and meeting with neighbors(p<.001) were significantly higher than the city, while social activities were social activities(p=.040), leisure activities (p=.036), and charity work(p<.001) was more active in the city than in farming and fishing areas. In middle age, connection to relatives(p<.001) and neighbors(p<.001) was significantly higher than the city, and social activities such as religious activities(p=.102) and leisure activities(p=.145) were higher in the city while social activities(p=.381) and charity work(p=.364) was high in farming and fishing areas, but there was no significant difference. Based on the results of this study, it was intended to propose suggestions for the promotion and maintenance of health according to the characteristics of single female households in the target audience age group according to the region.

Clinical Course and Outcomes of Patients with Severe Acute Respiratory Syndrome Coronavirus 2 Infection: a Preliminary Report of the First 28 Patients from the Korean Cohort Study on COVID-19

Eu Suk Kim,Bum Sik Chin,강창경,Nam Joong Kim,Yu Min Kang,Jae-Phil Choi,Dong Hyun Oh,Jeong-Han Kim,Boram Koh,Seong Eun Kim,Na Ra Yun,Jae Hoon Lee,Jin Yong Kim,Yeonjae Kim,Ji Hwan Bang,송경호,Hong Bin Kim,Ki- 대한의학회 2020 Journal of Korean medical science Vol.35 No.13

Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected pneumonia emerged in Wuhan, China in December 2019. In this retrospective multicenter study, we investigated the clinical course and outcomes of novel coronavirus disease 2019 (COVID-19) from early cases in Republic of Korea. Methods: All of the cases confirmed by real time polymerase chain reaction were enrolled from the 1st to the 28th patient nationwide. Clinical data were collected and analyzed for changes in clinical severity including laboratory, radiological, and virologic dynamics during the progression of illness. Results: The median age was 40 years (range, 20–73 years) and 15 (53.6%) patients were male. The most common symptoms were cough (28.6%) and sore throat (28.6%), followed by fever (25.0%). Diarrhea was not common (10.7%). Two patients had no symptoms. Initial chest X-ray (CXR) showed infiltration in 46.4% of the patients, but computed tomography scan confirmed pneumonia in 88.9% (16/18) of the patients. Six patients (21.4%) required supplemental oxygen therapy, but no one needed mechanical ventilation. Lymphopenia was more common in severe cases. Higher level of C-reactive protein and worsening of chest radiographic score was observed during the 5–7 day period after symptom onset. Viral shedding was high from day 1 of illness, especially from the upper respiratory tract (URT). Conclusion: The prodromal symptoms of COVID-19 were mild and most patients did not have limitations of daily activity. Viral shedding from URT was high from the prodromal phase. Radiological pneumonia was common from the early days of illness, but it was frequently not evident in simple CXR. These findings could be plausible explanations for the easy and rapid spread of SARS-CoV-2 in the community.

설득적 글쓰기와 정서 표현 글쓰기에 나타난 표현 양상 -강원국·김민식의 저서와 강연 분석을 중심으로-

권순희 ( Kwon Soonhee ),김여흘 ( Kim Yeoheul ),신소연 ( Shin Soyeon ),안병현 ( Ahn Byeonghyun ),원보람 ( Won Boram ) 서울대학교 국어교육과 2021 先淸語文 Vol.49 No.-

In order to examine the connection between logical and emotional writing and writing theory, Kang Wonguk’s book ‘President‘s writing’ and Kim Minsik’s book ‘Did you write every morning?’ were selected as the texts to analyze, and ‘Time to change the world, 15 minutes’, ‘How to Write Moving People (Kang Wonguk)’ and ‘Writing that Changes Pain to Pleasure (Kim Minsik)’ were selected for analysis. The analysis results are shown in the table below. The above difference comes from the difference between the purpose and direction of discourse between Kang Wonguk and Kim Minsik. Kang Wonguk explains his speeches and talks to persuade others in his writings and lectures. Therefore, Kang Wonguk’s writing focuses on logical writing, and the direction of writing is directed to the outside. Kim Minsik, on the other hand, mentions diaries and personal blog posts and talks about self-reflective and internal discourse. The direction of writing is directed inward, communicating with the self, and in the process of self-healing through writing.

Comparison of Prolonged Prothrombin and Activated Partial Thromboplastin Time Results With Thrombelastograph Parameters

Kim, Boram,Quan, Mei-Lian,Goh, Ri-Young,Kim, Ji-Eun,Woo, Kwang-Sook,Kim, Moo-Hyun,Han, Jin-Yeong American Society for Clinical Pathology 2013 Laboratory medicine Vol.44 No.4

<P><B>Objective:</B></P><P>The aim of this study was to investigate the performance and feasibility of the rotational thromboelastometry (ROTEM) profile by comparing prolonged prothrombin time (PT) and activated partial thromboplastin time (APTT) results with ROTEM parameters.</P><P><B>Methods:</B></P><P>We tested external TEM (EXTEM)– and internal TEM (INTEM)–activated determinations, mainly focusing on 5 basic parameters: Clotting time (CT), clot formation time (CFT), α angle, clot formation rate (CFR), and maximum clot firmness (MCF). We then compared PT and APTT results with ROTEM parameters.</P><P><B>Results:</B></P><P>We observed no significant correlations between any of the ROTEM EXTEM or INTEM parameters and PT results. Similarly, only 1 parameter, the INTEM CT value, was significantly correlated with APTT results (<I>r</I><SUP>2</SUP> = 0.165, <I>P</I> <.05).</P><P><B>Conclusion:</B></P><P>Much work is still needed to further evaluate ROTEM assay results stemming from clinical scenarios and standard laboratory testing.</P>

ERRATUM : Clinical Characteristics and Prognostic Factors of Lung Cancer in Korea: A Pilot Study of Data from the Korean Nationwide Lung Cancer Registry

Kim, Ho Cheol,Jung, Chi Young,Cho, Deog Gon,Jeon, Jae Hyun,Lee, Jeong Eun,Ahn, Jin Seok,Kim, Seung Joon,Kim, Yeongdae,Kim, Young-Chul,Kim, Jung-Eun,Lee, Boram,Won, Young-Joo,Choi, Chang-Min The Korean Academy of Tuberculosis and Respiratory 2019 Tuberculosis and Respiratory Diseases Vol.82 No.3

Treatment outcomes after adjuvant radiotherapy following surgery for patients with stage I endometrial cancer

Kim, Jiyoung,Lee, Kyung-Ja,Park, Kyung-Ran,Ha, Boram,Kim, Yi-Jun,Jung, Wonguen,Lee, Rena,Kim, Seung Cheol,Moon, Hye Sung,Ju, Woong,Kim, Yun Hwan,Lee, Jihae The Korean Society for Radiation Oncology 2016 Radiation Oncology Journal Vol.34 No.4

Purpose: The purpose of this study is to evaluate the treatment outcomes of adjuvant radiotherapy using vaginal brachytherapy (VB) with a lower dose per fraction and/or external beam radiotherapy (EBRT) following surgery for patients with stage I endometrial carcinoma. Materials and Methods: The subjects were 43 patients with the International Federation of Gynecology and Obstetrics (FIGO) stage I endometrial cancer who underwent adjuvant radiotherapy following surgery between March 2000 and April 2014. Of these, 25 received postoperative VB alone, while 18 received postoperative EBRT to the whole pelvis; 3 of these were treated with EBRT plus VB. The median EBRT dose was 50.0 Gy (45.0-50.4 Gy) and the VB dose was 24 Gy in 6 fractions. Tumor dose was prescribed at a depth of 5 mm from the cylinder surface and delivered twice per week. Results: The median follow-up period for all patients was 57 months (range, 9 to 188 months). Five-year disease-free survival (DFS) and overall survival (OS) for all patients were 92.5% and 95.3%, respectively. Adjuvant radiotherapy was performed according to risk factors and stage IB, grade 3 and lymphovascular invasion were observed more frequently in the EBRT group. Five-year DFS for EBRT and VB alone were 88.1% and 96.0%, respectively (p = 0.42), and 5-year OS for EBRT and VB alone were 94.4% and 96%, respectively (p = 0.38). There was no locoregional recurrence in any patient. Two patients who received EBRT and 1 patient who received VB alone developed distant metastatic disease. Two patients who received EBRT had severe complications, one each of grade 3 gastrointestinal complication and pelvic bone insufficiency fracture. Conclusion: Adjuvant radiotherapy achieved high DFS and OS with acceptable toxicity in stage I endometrial cancer. VB (with a lower dose per fraction) may be a viable option for selected patients with early-stage endometrial cancer following surgery.

Characterization of Glycoside Hydrolase in HMO Cluster I of Bifidobacterium infantis

Boram Kim,Sarang Kim,Nari Seo,Hyunjoo An,Jaehan Kim 한국식품영양과학회 2014 한국식품영양과학회 학술대회발표집 Vol.2014 No.10

Urinary metabolomic profiling for noninvasive diagnosis of acute T cell-mediated rejection after kidney transplantation

Kim, Sun-Young,Kim, Bo Kyung,Gwon, Mi-Ri,Seong, Sook Jin,Ohk, Boram,Kang, Woo Youl,Lee, Hae Won,Jung, Hee-Yeon,Cho, Jang-Hee,Chung, Byung Ha,Lee, Sang-Ho,Kim, Yeong Hoon,Yoon, Young-Ran,Kim, Chan-Duck Elsevier 2019 Journal of chromatography. B, Analytical technolog Vol.1118 No.-

<P><B>Abstract</B></P> <P>To improve early renal allograft function, it is important to develop a noninvasive diagnostic method for acute T cell-mediated rejection (TCMR). This study aims to explore potential noninvasive urinary biomarkers to screen for acute TCMR in kidney transplant recipients (KTRs) using untargeted metabolomic profiling.</P> <P>Urinary metabolites, collected from KTRs with stable graft function (STA) or acute TCMR episodes, were analyzed using liquid chromatography-mass spectrometry (LC-MS). Multivariate statistical analyses were performed to discriminate differences in urinary metabolites between the two groups. Receiver operating characteristic (ROC) curve analysis was used to evaluate the diagnostic performance of potential urinary biomarkers.</P> <P>Statistical analysis revealed the differences in urinary metabolites between the two groups and indicated several statistically significant metabolic features suitable for potential biomarkers. By comparing the retention times and mass fragmentation patterns of the chemicals in metabolite databases, samples, and standards, six of these features were clearly identified. ROC curve analysis showed the best performance of the training set (area under the curve value, 0.926; sensitivity, 90.0%; specificity, 84.6%) using a panel of five potential biomarkers: guanidoacetic acid, methylimidazoleacetic acid, dopamine, 4-guanidinobutyric acid, and <I>L</I>-tryptophan. The diagnostic accuracy of this model was 62.5% for an independent test dataset.</P> <P>LC-MS-based untargeted metabolomic profiling is a promising method to discriminate between acute TCMR and STA groups. Our model, based on a panel of five potential biomarkers, needs to be further validated in larger scale studies.</P> <P><B>Highlights</B></P> <P> <UL> <LI> We explored urinary biomarkers for acute TCMR using LC-MS-based metabolomics. </LI> <LI> OPLS-DA well distinguished between acute TCMR and STA groups. </LI> <LI> Multivariate statistical analyses revealed differences in urinary metabolites. </LI> <LI> ROC curve analysis evaluated the performance of potential urinary biomarkers. </LI> </UL> </P>

Postmastectomy Radiotherapy in Patients with pT1-2N1 Breast Cancer Treated with Taxane-Based Chemotherapy: A Retrospective Multicenter Analysis (KROG 1418)

Kim, Yeon-Joo,Park, Won,Ha, Boram,Park, Boram,Joo, Jungnam,Kim, Tae Hyun,Park, In Hae,Lee, Keun Seok,Lee, Eun Sook,Shin, Kyung Hwan,Kim, Haeyoung,Yu, Jeong Il,Choi, Doo Ho,Huh, Seung Jae,Wee, Chan Woo 대한암학회 2017 Cancer Research and Treatment Vol.49 No.4

<P><B>Purpose</B></P><P>The purpose of this study was to evaluate the impact of postmastectomy radiotherapy (PMRT) on loco-regional recurrence-free survival (LRRFS), disease-free survival (DFS), and overall survival (OS) in pT1-2N1 patients treated with taxane-based chemotherapy. </P><P><B>Materials and Methods</B></P><P>We retrospectively reviewed the medical data of pathological N1 patients who were treated with modified radical mastectomy and adjuvant taxane-based chemotherapy in 12 hospitals between January 2006 and December 2010. </P><P><B>Results </B></P><P>We identified 714 consecutive patients. The median follow-up duration was 69 months (range, 1 to 114 months) and the 5-year LRRFS, DFS, and OS rates were 97%, 94%, and 98%, respectively, in patients who received PMRT (PMRT [+]). The corresponding figures were 96%, 90%, and 96%, respectively, in patients who did not receive PMRT (PMRT [–]). PMRT had no significant impact on survival. Upon multivariable analysis, only the histological grade (HG) was statistically significant as a prognostic factor for LRRFS and DFS. In a subgroup analysis of HG 3 patients, PMRT (+) showed better DFS (p=0.081).</P><P><B>Conclusion </B></P><P>PMRT had no significant impact on LRRFS, DFS, or OS in pT1-2N1 patients treated with taxane-based chemotherapy. PMRT showed a marginal benefit for DFS in HG 3 patients. Randomized studies are needed to confirm the benefit of PMRT in high risk patients, such as those with HG 3.</P>

Clinical Characteristics and Prognostic Factors of Lung Cancer in Korea: A Pilot Study of Data from the Korean Nationwide Lung Cancer Registry

Kim, Ho Cheol,Jung, Chi Young,Cho, Deog Gon,Jeon, Jae Hyun,Lee, Jeong Eun,Ahn, Jin Seok,Kim, Seung Joon,Kim, Yeongdae,Kim, Young-Chul,Kim, Jung-Eun,Lee, Boram,Won, Young-Joo,Choi, Chang-Min The Korean Academy of Tuberculosis and Respiratory 2019 Tuberculosis and Respiratory Diseases Vol.82 No.2

Background: Lung cancer is a leading cause of morbidity and mortality worldwide, and the incidence continues to rise. Although many prognostic factors have been identified, the clinical characteristics and outcomes in Korean lung cancer patients are not well defined. Methods: Of the 23,254 new lung cancer cases registered at the Korea Central Cancer Registry in 2013, total 489 patients from 19 hospitals were abstracted by the Korean Central Cancer Registry. The clinical data retrospectively analyzed, patients were followed up until December 2015. Results: The median age was 69 years (interquartile range, 60-74 years); 65.4% were male and 62.1% were ever-smokers. Cough was the most common initial symptom (33.5%); 13.1% of patients were asymptomatic. While squamous cell carcinoma was the most common subtype in male patients (37.2%), adenocarcinoma was the most frequent histological type in all patients (48.7%) and females (76.3%). The majority of patients received treatment (76.5%), which included surgery, radiation therapy, and chemotherapy. Older age (hazard ratio [HR], 1.037), lower body mass index (HR, 0.904), ever-smoker (HR, 2.003), small cell lung cancer (HR, 1.627), and distant metastasis (HR, 3.990) were independent predictors of mortality. Patients without symptoms (HR, 0.387) and without treatment (HR, 0.364) were associated with a favorable outcome in multivariate Cox analysis. Conclusion: Lung cancer in Korea occurs predominantly in elderly patients, with adenocarcinoma being the most frequent subtype. The prognosis was poorer in ever-smokers and older, malnourished, and untreated patients with advanced lung cancer.