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RISS 인기검색어
- 검색키워드
- 저자 : Boonsil Jang (검색결과 2 건)
- 무료
- 기관 내 무료
- 유료
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SEM Findings on the Dentinal Tubules Changes by Application of the Desensitization Agents
Boonsil Jang,Su-Kyung Jwa,Yun Hwa Choi 대한예방치과학회 2012 International Journal of Clinical Preventive Denti Vol.8 No.1
Objective: In order to observe and to compare several desensitization agents for dentinal tuble changes, Gluma, MS coat, 2% NaF, 10% SnF2 and SE bond were prepared. Methods: 5 extracted 3rd Molar were prepared, and devided with 6 pieces per a tooth for 30 specimens, classified them with 6 groups as group 1 as without any treatment, group 2 as applied with Gluma for 3 times, group 3 as MS coat for 3 times, group 4 as 2% NaF for 4 times, group 5 as 10% SnF2 and group 6 as SE bond for a time. SEM observation was done for all specimens for 2 portions per a sample and the number and degree of the obstacle of dentinal tubules were calculated. Results: It revealed the closing phenomina in all experimental group's samples were more in numbers of the degree than in control group (p<0.05), SE bond group was the most in closing the dentinal tubles and 10% SnF2 group was next, and MS coat, Gluma, and 2% NaF in sequence. There was no significant differences between in each experimental group by one way ANOVA test, with Tuckey or Sheffe test, otherwise there was a significant difference in statistical between in Gluma, 2% NaF and SE bond group by Dunkan test (p<0.05). Conclusion: All experimental group's agents can be used for desensitization agents in hypersensitive dentin clinically, and SE bond was the most recommended for severe hyper sensitive dental patient.
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Lycorine의 사람 구강 암 세포주에서 survivin 단백질 분해 증진으로 세포자멸사
Joseph H. Jeong,Nam-Pyo Cho,Boonsil Jang 대한구강악안면병리학회 2017 대한구강악안면병리학회지 Vol.41 No.1
Lycorine, a natural alkaloid extracted from the Amaryllidaceae plant family, was reported to various physiological and pharmacological effects including anti-cancer activity. Nevertheless, there is no report of the anticancer effect of lycorine in oral cancer cells. The effects of lycorine on cell proliferation and apoptosis were examined through trypan blue exclusion assay, 4’-6-diamidino-2-phenylindole (DAPI) stain, Live/Dead assay, Western blot analysis and RT-PCR. Lycorine suppressed cell viability and induced apoptosis in MC3 and HSC-3 cell lines. Lycorine decreased survivin protein but did not affect its mRNA. It regulated survivin through accelerating protein degradation in a time-dependent manner although neither proteasome nor lysosome was not associated with lycorine-mediated protein degradation. Collectively, our results suggest that lycorine may be a potential therapeutic anti-cancer drug candidate for the treatment of human oral cancer.
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