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4D printed Microvehicle for Gastric Cancer Therapy
Darmawan Bobby Aditya,Dohoon Gong(공도훈),Hyeon Gyu Park(박현규),Gwangjun Go(고광준),Seok-Jae Kim(김석재),Nguyen Kim Tien,Zheng Shirong,Nan Minghui,Ratri Monica Cahyaning,Hyungwoo Kim(김형우),Doyeon Bang(방도연),Jong-O 한국자동차공학회 2021 한국자동차공학회 지부 학술대회 논문집 Vol.2021 No.12
Gold Nanoparticles Embedded Microrobots for Real-time X-ray Imaging
Bobby Aditya Darmawan,Sang Bong Lee,Gwangjun Go,Chang-Sei Kim,Doyeon Bang,Jong-Oh Park,Eunpyo Choi 제어로봇시스템학회 2020 제어로봇시스템학회 국제학술대회 논문집 Vol.2020 No.10
Microrobots have been demonstrated to have the potential in medical approaches, such as for targeted drug delivery. However, real-time tracking and imaging are still one of the major issues faced by microrobots. Here, we fabricated helical microrobots based on self-folding technique, and we performed double coating of gold nanoparticles (AuNPs) to the surface of microrobots to enhance the image quality under X-ray. The result shows that, we successfully coated the AuNPs into the self-rolled microrobots, and it increases the image quality when compared to non-coated microrobots. Despite the fact that there still remain some challenges to achieve successful applications of microrobots, we believe that the potential of this study can contribute to reduce the challenges faces in the medical microrobot fields.
Sang Bong Lee,Ho Won Lee,Bobby Aditya Darmawan,In-Kyu Lee,Sung Jin Cho,Jungwook Chin,Sang Kyoon Kim,Jong-Oh Park,Kil Soo Kim,Sang-Woo Lee,Jaetae Lee,Yong Hyun Jeon 한국공업화학회 2020 Journal of Industrial and Engineering Chemistry Vol.88 No.-
We report the fabrication of multifunctional theranositic biomaterials via non-covalent, rapid, andeffective encapsulation of 1,10dioctadecyl-3,3,30,30-tetrametylindotrucarbocyanine iodide (DIR)onto mesoporous silica nanoparticles by coating the surface of polyethylene glycol (PEG-DIR@MSN). PEG-DIR@MSNs exhibited great stability with excellent biocompatibility and photothermal conversionproperties. PEG-DIR@MSN allowed for not only the detection of various types of tumor and ischemiclesions but also photothermal therapy against breast cancer in living mice, suggesting that PEGDIR@MSN is a valuable multifunctional theranostic platform.