Determinants of Financial Information Disclosure: An Empirical Study in Vietnam’s Stock Market

Thu Thi Bich PHAM 한국유통과학회 2022 The Journal of Asian Finance, Economics and Busine Vol.9 No.4

The focus of the research is to determine the amount of financial information disclosure and the factors that influence it for non-financial enterprises listed on Vietnam’s stock exchange. To evaluate the level of financial information disclosure, the study uses a set of disclosure indexes from the world’s leading credit rating agency, Standard and Poor’s (S&P). It makes some revisions in compliance with regulations for information disclosure on the Vietnam stock market. The study collects data in the form of annual reports for the year 2017-2020 from 350 non-financial firms listed on Vietnam’s stock exchange and then uses a multivariate regression model to assess the effects of factors on the amount of financial information disclosure. The findings show that the size of the firm, the size of the board of directors, and foreign ownership all have a positive impact on financial transparency; however, the number of years the company has a negative impact. According to the findings of this study, companies with more total assets, a larger board of directors, and a higher rate of foreign ownership publish more financial information. Still, long-term listed companies on the stock exchange tend to disclose less.

Zanthoxylum rhetsa Stem Bark Extract Inhibits LPS-induced COX-2 and iNOS expression in RAW 264.7 Cells via the NF-kB Inactivation

Nguyen Bich Thu,Trinh Nam Trung,Do Thi Ha,Nguyen Minh Khoi,Nguyen Viet Than,Thipthaviphone Soulinho,Nguyen Hai Nam,Tran Thi Phuong,배기환 한국생약학회 2010 Natural Product Sciences Vol.16 No.4

The methanol extract of Zanthoxylum rhetsa (MZRR) were evaluated for its ability to suppress the formation of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) in lipopolysaccharide (LPS)-activated RAW 264.7 macrophages. MZRR presented an inhibition of LPS-induced production of nitric oxide (NO) and prostaglandin E2 (PGE2) in RAW 264.7 macrophages. Western blotting and RT-PCR analyses demonstrated that MZRR significantly inhibited the protein and mRNA expressions of iNOS and COX-2 in LPS-activated macrophages in a dose-dependent manner. LPS-induced COX-2, iNOS, and nuclear factor kappa beta (NF-kB) activity were also decreased in the presence of MZRR. The production of tumor necrosis factor-a (TNF-a), the mRNA expression levels of pro-inflammatory cytokines, including TNF-a and IL-1b, were reduced after MZRR administration in a dose dependent-manner. These results suggest that the MZRR extract involved in the inhibition of iNOS and COX-2 via the NF-kB pathway, revealing a partial molecular basis for anti-inflammatory properties of the MZRR extract.

Screening of Vietnamese Medicinal Plants for Cytotoxic Activity

Nguyen Bich Thu,Trinh Nam Trung,Do Thi Ha,Nguyen Minh Khoi,Tran Viet Hung,Tran Thi Hien,Yim Namhui,배기환 한국생약학회 2010 Natural Product Sciences Vol.16 No.1

Thirty-two methanol extracts of thirty-one Vietnamese medicinal plants were evaluated for the cytotoxic activity against five human cancer cell lines, including A549, MCF-7, HT 1080, Huh-7, and HepG2. Of these, the nine extracts of Acanthopanax trifoliatus (4), Acanthopanax gracilistylus (5), Siegesbeckia orientalis (10), Betula alnoides (11), Passiflora edulis (18), Zanthoxylum simulans (leaf, 23), Adenosma caeruleum (26), Solanum verbascifolium (29), and Alpinia malaccensis (31), exhibited high potent cytotoxic activity showing a certain degree of selectivity against the different cell types, with IC50 values ranging from 2.1 to 3.8 mg/mL.

한국 소비자의 온라인 식품구매 결정요인과 식품 공급사슬 다각화에 관한 연구

정재은(Jae-Eun Chung),Nguyen Thi Thu Ha(Thi Thu Ha Nguyen),Nguyen Thi Bich Loan(Thi Bich Loan Nguyen),문희철(Hee-Cheol Moon) 중앙대학교 한국전자무역연구소 2020 전자무역연구 Vol.18 No.1

연구목적: 최근 온라인 공급업체들은 마케팅 방법과 유통방법의 다각화를 통하여 소비자 만족도 향상에 기여하고 있으며, 이에 따라 온라인 식품시장이 급격히 성장하고 있다. 본 연구는 이러한 온라인 식품시장에서 한국 소비자의 식품구매 결정요인을 실증적으로 분석해 식품 공급사슬 현황에 대한 시의 적절한 시사점을 제공하고자 한다. 논문구성/논리: 연구의 논리성 및 시의 적절성을 제시하기 위해 본 연구에서는 이론적인 연구배경과 선행연구에 대해 제시한 후 이를 참고로 연구모형과 연구가설을 구축하였다. 연구가설 검증에는 SPSS 통계패키지와 AMOS 프로그램이 활용되었으며, 요인의 타당성과 신뢰성 및 측정모형의 적합도를 검증한 후 가설검증을 이행하여 실증분석 결과의 신뢰도를 확보하였다. 본 연구의 차별성을 확보한 조절효과 검증에는 다집단분석 방법이 활용되었다. 결과: 본 연구의 실증분석 결과에 의하면 온라인 공급업자가 제공하는 식료품과 관련정보의 높은 신뢰도는 온라인 식품구매 방법에 대한 소비자의 태도에 대해 긍정적인 영향을 미치는 것으로 나타났다. 또한 온라인 식품 구매 방법에 대해 소비자가 유용하다고 인지할수록 소비자가 온라인 식품구매에 대해 긍정적인 태도를 가지게 되며, 이는 소비자의 구매하고자 하는 의도에도 직접적인 영향을 미치는 것으로 분석되었다. 마지막으로 식료품의 구분에 따른 조절효과가 유의한 것으로 검증된 것에서 제품구분에 따른 소비자의 구매 결정에 대한 영향요인이 다르며, 이는 한국 식품시장의 공급사슬이 다변화, 다각화되고 있어 다른 시각적 접근의 필요성을 제시하였다. 독창성/가치: 본 연구는 최근 소비가 급증하고 있는 한국의 온라인 식품시장에 대해 새로운 시각적 접근의 필요성을 제시하고 식료제품의 구분을 조절적으로 분석해 소비자의 결정요인이 다르게 작용하고 있음을 실증적으로 제시하였다. Purpose: Recently, online suppliers have contributed to improving customer satisfaction through diversification of marketing methods and distribution methods. As a result, the online food market is growing rapidly. This study empirically analyzed the determinants of food purchase of Korean consumers in this online food market, and tried to provide timely implications for the current Korean food supply chain status. Composition/Logic: In order to suggest the logic and timeliness of the study, this study first described the theoretical background and previous studies. Based on this, the research model and hypotheses were constructed. To test the hypothesis, SPSS statistical package and AMOS program were used. After verifying the validity and reliability of the factors and the model fit, the hypothesis verification was conducted to secure the reliability of the empirical analysis results. The multi-group SEM analysis was used to verify the moderating effect, which secured the differentiation of this study. Findings: According to the empirical results of this study, the high reliability of food products and related information provided by online suppliers has a positive effect on consumers attitudes toward online food purchase methods. In addition, as consumers perceive the usefulness of online food purchase method, consumers have a positive attitude toward online food purchase, which has a direct effect on their purchase intention also. Lastly, it was analyzed that the moderating effect of food products classification was significant. This suggests the need for a different approach as the supply chain of the Korean online food market is diversifying. Originality/Value: This study suggested the necessity of a new approach to Korea s online food market, which has recently been increasing rapidly, and empirically suggested that consumers determinants are working differently by analyzing the moderate effect of food products classification.

Corrigendum to’ Anxiolytic effect of Korean Red Ginseng through upregulation of serotonin and GABA transmission and BDNF expression in immobilized mice’ [Journal of Ginseng Research Volume 46, Issue 6, November 2022, Pages 819-829]

Bich Phuong Bui,Phuong Linh Nguyen,Ha Thi Thu Do,Jungsook Cho 고려인삼학회 2023 Journal of Ginseng Research Vol.47 No.1

Identification of three novel mutations in PCNT in vietnamese patients with microcephalic osteodysplastic primordial dwarfism type II

Thu Hien Nguyen,Ngoc‑Lan Nguyen,Chi Dung Vu,Can Thi Bich Ngoc,Ngoc Khanh Nguyen,Huy Hoang Nguyen 한국유전학회 2021 Genes & Genomics Vol.43 No.2

Background Primordial dwarfsm (PD) is a group of genetically heterogeneous disorders related to developmental disabilities occurring in the uterus and prolongs during all stages of life, resulting in short stature, facial deformities and abnormal brain. Objective To determine the exact cause of the disease in two Vietnamese patients priory diagnosed with PD by severe preand postnatal growth retardation with marked microcephaly and some bone abnormalities. Methods Whole-exome sequencing was performed for the two patients and mutations in genes related to PD were screened. Sanger sequencing was applied to examine the mutations in the patients of their families. Results Three novel mutations in the PCNT gene which have not been reported previously were identifed in the two patients. Of which, two frameshift mutations (p.Thr479Profs*6 and p.Glu2742Alafs*8) were detected in patient I and one stop-gained mutation (p.Gln1907*) was detected in the patient II. These mutations may result in a truncated PCNT protein, leading to an inactivated PACT domain corresponding to residue His3138–Trp3216 of PCNT protein. Therefore, the three mutations may cause a defciency of protein functional activity and result in the phenotypes of primordial dwarfsm in the two patients. Conclusions Clinical presentations in combination with genetic analyses supported an accurate diagnosis of the two patients with microcephalic osteodysplastic primordial dwarfsm type II (MOPD II). In addition, these results have important implications for prenatal genetic screening and genetic counseling for the families.

Anxiolytic effect of Korean Red Ginseng through upregulation of serotonin and GABA transmission and BDNF expression in immobilized mice

Bui, Bich Phuong,Nguyen, Phuong Linh,Do, Ha Thi Thu,Cho, Jungsook The Korean Society of Ginseng 2022 Journal of Ginseng Research Vol.46 No.6

Background: Anxiolytic properties of Korean Red Ginseng (KRG) have been previously reported. However, the exact mechanism(s) of action remains to be elucidated. The present study investigated the effect of KRG on immobilization-induced anxiety-like behaviors in mice and explored the involvement of the serotonin and GABA systems and BDNF in the anxiolytic action. Methods: Mice were orally administered with KRG (200 mg/kg/day) for 4 weeks and immobilized once daily for 2 h. p-Chlorophenylalanine (p-CPA) was intraperitoneally injected on day 22-28, and flumazenil or bicuculline was injected on day 25-28. After behavioral evaluations, brains were dissected for biochemical analyses. Results: KRG improved immobilization-induced anxiety-like behaviors in mice, as assessed by the elevated plus maze (EPM) and marble burying tests (MBT). The anxiolytic effect of KRG was comparable to that of fluoxetine, a reference drug clinically used for anxiety disorders. A serotonin synthesis inhibitor, p-CPA, blocked the effect of KRG in the EPM and MBT, indicating the requirement of serotonin synthesis for anxiolytic action. In addition, the anxiolytic effect of KRG was inhibited by bicuculline (a GABA_A antagonist) in MBT, implying the involvement of GABA transmission. Western blotting analyses revealed that KRG upregulated the expression of tryptophan hydroxylase and GABA_A receptor in the brain, which was blocked by p-CPA. Enhanced BDNF expression by KRG in the hippocampus was also indicated to mediate the anxiolytic action of KRG in immobilized mice. Conclusion: KRG exhibited the anxiolytic effect in immobilized mice by multiple mechanisms of action, involving enhanced serotonin and GABA transmissions and BDNF expression.

Changes in Vietnamese Male Smokers' Reactions Towards New Pictorial Cigarette Pack Warnings Over Time

Tran, Thu Ngan,Le, Vu Anh,Nguyen, Thi Tuyet My,Nguyen, Ngoc Bich Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.no.sup1

Printing of pictorial health warnings (PHWs) on cigarette packages became obligatory by the Vietnam Law on Prevention and Control of Tobacco Harm in May 2013. Literature from high-income countries suggests that PHWs motivate smokers to quit smoking although their long-term effects have been questioned due to reduction of impact over time. This study aimed to assess the salience of PHWs and smokers' reactions towards PHWs over time. In May 2014 and May 2015, a cross-sectional questionnaire-based household survey was administered to respectively 1,462 and 1,509 Vietnamese male smokers aged 18 to 35. The result showed that salience of the PHWs 2 years after the implementation was higher than at the point of 1 year after the implementation. The proportion of respondents who tried to avoid noting the PHWs was reduced from 35% in wave 1 to 23% in wave 2. However, "Tried to avoid looking/thinking about the PHWs" increased 1.5 times the odds of presenting quit intention compared to those respondents who did not try to avoid looking/thinking about the PHWs (OR=1.5; 95%CI: 1.2-2.0). In conclusion, avoidance regarding PHWs may not work as a barrier when aiming at a higher level of quit intention. Salience of the PHWs may increase in the period shortly after their introduction onto packs but can be expected to decrease with time. In other words, it might be advisable to change or renew PHWs after a period of implementation to maintain their beneficial effects.

Audit Quality and Stock Return Co-Movement: Evidence from Vietnam

PHAM, Chi Bich Thi,VU, Thu Minh Thi,NGUYEN, Linh Ha,NGUYEN, Dung Duc Korea Distribution Science Association 2020 The Journal of Asian Finance, Economics and Busine Vol.7 No.7

This paper aims to explore the relationship between the quality of the audit and the level of stock return co-movement in the context of the Vietnamese emerging market. The empirical study is designed based on the quatitative method and deductive approach. The panel dataset includes 256 listed firms from different industries,with 1115 firm-year observations on Ho Chi Minh City Stock Exchange for the period from 2014 to 2018. In the research, we built the econometric regression model, using stock return synchronicity and audit quality as the dependent and independent variable, respectively. Some control variables are also added to the econometric regression models as they are well-documented in prior research to have an effect on stock price synchronicity. To improve the accuracy of the regression coefficients, beside the Ordinary Least Squares, we employ the Random Effects Model and the Fixed Effects Model for better statistical analysis of panel data set. The results show that the quality of the audit is positively correlated to stock price synchronicity. This finding suggests that stock returns of companies with higher quality of the audit are more synchronous with the market. Results for other control variables also support our reasoning for the main findings.

Isolation and Cytotoxic Potency of Endophytic Fungi Associated with Dysosma difformis, a Study for the Novel Resources of Podophyllotoxin

Hoa Thi Tran,Giang Thu Nguyen,Hong Ha Thi Nguyen,Huyen Thi Tran,Quang Hong Tran,Quang Ho Tran,Ngoc Thi Ninh,Phat Tien Do,Ha Hoang Chu,Ngoc Bich Pham 한국균학회 2022 Mycobiology Vol.50 No.5

Endophytic fungi are promising sources for the production of podophyllotoxin-an important anticancer compound, replacing depleted medical plants. In this study, the endophytes asso- ciated with Dysosma difformis-an ethnomedicinal plant species were isolated to explore novel sources of podophyllotoxin. Fifty-three endophytic fungi were isolated and identified by morphological observation and ITS-based rDNA sequencing, assigning them to 27 genera in 3 divisions. Fusarium was found the most prevalent genus with a colonization frequency of 11.11%, followed by Trametes (9.26%) and Penicillium (7.41%). Phylogenetic trees were constructed for the endophytic fungi community in two collection sites, Ha Giang and Lai Chau, revealing the adaptation of the species to the specific tissues and habitats. Cytotoxic activity of endophytic fungal extracts was investigated on cancer cell lines such as SK-LU-1, HL-60, and HepG2, demonstrating strong anti-cancer activity of six isolates belonging to Penicillium, Trametes, Purpureocillium, Aspergillus, and Ganoderma with IC50 value of lower than 10 mg/mL. The presence of podophyllotoxin was indicated in Penicillium, Trametes, Aspergillus and for the first time in Purpureocillium and Ganoderma via high-performance liquid chromatography, which implied them as a potential source of this anti- cancer compound.