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Alloxan으로 유도된 당뇨병 mice의 생리 활성 연구
하배진 신라대학교 자연과학연구소 1997 自然科學論文集 Vol.3 No.-
This study was performed to investigate the lipidperoxide, AST and ALT, BUN and blood glucose level in alloxan induced diabetic mice. 1. The lipidperoxide of the liver and kidney increased each 1.36, 1.44 times as much as in the control group. 2. AST and ALT in the diabetic group increased each 4.19, 8.79 times as much as in the control group. 3. The glucose level and BUN in the diabetic group increased each 2.71, 2.34 times as much as in the control group.
박진주(Jin-Ju Park),배초롱(Cho-Rong Bea),이소정(So-Jeong Lee),하얀(Yan Ha) 한국컴퓨터정보학회 2011 한국컴퓨터정보학회 학술발표논문집 Vol.19 No.1
본 논문에서는 사람들의 관심사를 충족시킬 주제로, 소셜 네트워크(SNS)를 활성화 하여 다자간의 대화를 통한 비즈니스 마케팅을 유도하며 기존의 블로그 형식의 커뮤니티와 쇼핑몰의 형태를 결합한 신개념 네트워크를 제안하고 구현한다. 소셜 네트워크를 활성화 시키고, 패션이라는 주제로 사람들의 개성을 살릴 수 있는 아이템을 선정. 각자의 특성이 담긴 "아바타"를 제작, 본 논문 내에서 각자가 특성이 담긴 패셔니스타가 될 수 있는 공간이 된다. 실제 의류, 소품과 제법 유사하게 만든 이미지를 나와의 신체 비율이 비슷한 아바타에 직접 피팅을 시킬 수 있으며 자신이 직접 입어보지 않고, 시간과 공간의 제약을 받지 않는 것이 특징이다. 다자간의 실시간 커뮤니케이션을 통해 네트워킹도 활성화 될 뿐더러 기업과의 연계를 통해 구매로까지 이어질 수 있는 공간을 만든다.
Park Hae-Young,Kwon Jin-Won,Kim Hye-Lin,Kwon Sun-Hong,Nam Jin Hyun,Min Serim,Oh In-Sun,Bea Sungho,Choi Sun Ha 대한의학회 2023 Journal of Korean medical science Vol.38 No.21
Background: Regimens for the treatment of multidrug-resistant tuberculosis (MDR-TB) have been changed from injectable-containing regimens to all-oral regimens. The economic effectiveness of new all-oral regimens compared with conventional injectable-containing regimens was scarcely evaluated. This study was conducted to compare the cost-effectiveness between all-oral longer-course regimens (the oral regimen group) and conventional injectablecontaining regimens (the control group) to treat newly diagnosed MDR-TB patients. Methods: A health economic analysis over lifetime horizon (20 years) from the perspective of the healthcare system in Korea was conducted. We developed a combined simulation model of a decision tree model (initial two years) and two Markov models (remaining 18 years, sixmonth cycle length) to calculate the incremental cost-effectiveness ratio (ICER) between the two groups. The transition probabilities and cost in each cycle were assumed based on the published data and the analysis of health big data that combined country-level claims data and TB registry in 2013–2018. Results: The oral regimen group was assumed to spend 20,778 USD more and lived 1.093 years or 1.056 quality-adjusted life year (QALY) longer than the control group. The ICER of the base case was calculated to be 19,007 USD/life year gained and 19,674 USD/QALY. The results of sensitivity analyses showed that base case results were very robust and stable, and the oral regimen was cost-effective with a 100% probability for a willingness to pay more than 21,250 USD/QALY. Conclusion: This study confirmed that the new all-oral longer regimens for the treatment of MDR-TB were cost-effective in replacing conventional injectable-containing regimens.