Helicobacter pylori vacA d1 Genotype Predicts Risk of Gastric Adenocarcinoma and Peptic Ulcers in Northwestern Iran

Basiri, Zeinab,Safaralizadeh, Reza,Bonyadi, Morteza Jabbarpour,Somi, Mohammad Hossein,Mahdavi, Majid,Latifi-Navid, Saeid Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.4

Background: There is a close relationship between Helicobacter pylori (H pylori)-specific factors and different gastroduodenal diseases. The present study aimed to investigate the prevalence of vacA d1, d2 genotypes in the H pylori isolates from patients with gastric adenocarcinoma, peptic ulcer disease (PUD) and gastritis in East Azerbaijan region, where the incidence of gastric cancer (GC) is high. Strains isolated from this area are likely to be of European ancestry. Materials and Methods: In this study, genotyping of the vacA d region of 115 isolates obtained from patients with different gastrodoudenal diseases was accomplished by PCR methods. In addition to PCR amplification of H pylori 16S rDNA, rapid urease tests or histological examination were used to confirm the presence of H pylori in biopsy specimens. Data were collected and analyzed using SPSS version 19. Results: Of the total of 83 H pylori isolates, 36 (43.4%) contained the d1 allele and 47 (56.6%) were subtype d2. The results of the multiple linear/logistic regression analysis showed high correlation between allele d1 and gastric adenocarcinoma or PUD. Conclusions: This study suggests that the H pylori vacA d1 genotype helps predict risk for gastric adenocarcinoma and PUD in East Azerbaijan, Iran.

Difference in the Incidences of the Most Prevalent Urologic Cancers from 2003 to 2009 in Iran

Basiri, Abbas,Shakhssalim, Nasser,Jalaly, Niloofar Yahyapour,Miri, Hamid Heidarian,Partovipour, Elham,Panahi, Mohammad Hossein Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.3

Background: Urological cancers represent a major public problem associated with high mortality and morbidity. The pattern of these cancers varies markedly according to era, region and ethnic groups, but increasing incidence trends overall makes focused epidemiological studies important. The aim of the present study was to assess the incidence of most prevalent urological cancers in Iran from 2003 to 2009. Materials and Methods: The data for this study were obtained from the population-based Cancer Registry Center of the Iran Ministry of Health and Medical Education. Differences of mean age and age distributions of each cancer were compared between 2003 and 2009 in men and women. Results: Bladder cancer was the most common urologic cancer in both genders. The rate difference of age standardized ratio (ASR) of bladder and renal cell carcinoma in women were 1.54 and 2.01 percent per 100,000 population from 2003 to the 2009, respectively. In men, the rate difference of age standardized ratio of prostate, testis, kidney and bladder cancer was also 2.23, 1.2, 1.8 and 1.5 percent per 100,000 population from 2003 to 2009, respectively. The mean ages of patients in all cancers in both genders did not differ significantly through time (p value>0.05) but the distribution of ages of patients with bladder and prostate cancer changed significantly from 2003 to 2009 (p value<0.001). Conclusions: The results of present study suggest the general pattern and incidence of urological cancers in Iran are changing, the observed increase pointing to a need for urological cancer screening programs.

Predictive factors of death in neonates with hypoxic-ischemic encephalopathy receiving selective head cooling

Basiri, Behnaz,Sabzehei, Mohammadkazem,Sabahi, Mohammadmahdi The Korean Pediatric Society 2021 Clinical and Experimental Pediatrics (CEP) Vol.64 No.4

Background: Severe perinatal asphyxia results in multiple organ involvement, neonate hospitalization, and eventual death. Purpose: This study aimed to investigate the predictive factors of death in newborns with hypoxic-ischemic encephalopathy (HIE) receiving selective head cooling. Methods: This cross-sectional descriptive-retrospective study was conducted from 2013 to 2018 in Fatemieh Hospital of Hamadan and included 51 newborns who were admitted to the neonatal intensive care unit with a diagnosis of HIE. Selective head cooling for patients with moderate to severe HIE began within 6 hours of birth and continued for 72 hours. The required data for the predictive factors of death were extracted from the patients' medical files, recorded on a premade form, and analyzed using SPSS ver. 16. Results: Of the 51 neonates with moderate to severe HIE who were treated with selective head cooling, 16 (31%) died. There were significant relationships between death and the need for advanced neonatal resuscitation (P=0.002), need for mechanical ventilation (P=0.016), 1-minute Apgar score (P=0.040), and severely abnormal amplitude-integrated electroencephalography (a-EEG) (P=0.047). Multiple regression of variables or data showed that the need for advanced neonatal resuscitation was an independent predictive factor of death (P=0.0075) and severely abnormal a-EEG was an independent predictive factor of asphyxia severity (P=0.0001). Conclusion: All cases of neonatal death in our study were severe HIE (stage 3). Advanced neonatal resuscitation was an independent predictor of death, while a severely abnormal a-EEG was an independent predictor of asphyxia severity in infants with HIE.

Degradation of azo dye C.I. Acid Red 18 in aqueous solution by ozone-electrolysis process

J. Basiri Parsa,M. Golmirzaei,M. Abbasi 한국공업화학회 2014 Journal of Industrial and Engineering Chemistry Vol.20 No.2

In this paper, the degradation of azo dye C.I. Acid Red 18 (AR18) with initial concentration of 100 mg L-1 in aqueous solution by ozone-electrolysis process (OEP) as hybrid method of advance oxidation processwas investigated. All experiments were performed in a 450 mL mixed semi-batch reactor to obtain theoptimal conditions. The effects of NaCl concentration as supporting electrolyte, current density andinitial pH on the removal efficiency of AR18 solution were investigated. The efficiency of color and TOCremoval were compared as functional of degradation and decolorization of AR18. The results of UV/visspectra showed that the AR18 structures were destroyed under ozone-electrolysis reaction. Thisinvestigation revealed ozone-electrolysis presents good efficiency for both solution decolorization andtotal organic carbon (TOC) removal. Results of experiments indicated that ozone-electrolysis process hasa synergistic effect on decolorization rate of AR18.

Evaluation of electro-coagulation method for decolorization and degradation of organic dyes in aqueous solutions

Jalal Basiri Parsa,Farideh Nabizadeh Chianeh 한국화학공학회 2012 Korean Journal of Chemical Engineering Vol.29 No.11

This research has two parts: at first part electro coagulation (EC) method was used to remove the dye Direct Black 22 (DB22 (in aqueous media. All experiments were done in a 2 liter reactor with two electrodes made of steel (SS-304) as cathodes and one aluminum electrode as anode. Parameters affecting the process, such as anode material,electrolyte concentration, current density, initial pH of solution and the initial dye concentration, were investigated. Total amount of consumed energy was used for determination of optimal conditions. According to the results obtained for DB22 at optimized conditions, color and COD removal percentage were 92% and 85%, respectively. In addition,the current efficiency for aluminum anode in removal of DB22 was 90%. At the second part of the research work, color removal by EC for six different dyes was evaluated. The results showed that dye structure and anode type are very important factors on performance of the process.

Modeling and optimizing of electrochemical oxidation of C.I. Reactive Orange 7 on the Ti/Sb–SnO2 as anode via response surface methodology

J. Basiri Parsa,M. Abbasi,Z. Merati 한국공업화학회 2013 Journal of Industrial and Engineering Chemistry Vol.19 No.4

The decolorization and degradation of an organic dye, Reactive Orange 7 (RO7) in aqueous media by electrochemical oxidation process using Ti/Sb–SnO2 electrode as anode was modeled and optimized using response surface methodology (RSM) based on central composite design (CCD). The anode electrode was prepared using dip-coating and thermal decomposition method. Accordingly reduced quadratic model was developed to give the substrate color removal efficiency percentage as function of effective parameters such as: initial dye concentration, pH of the solution, electrolyte concentration and current density. The fit of the model is checked by the determination coefficient (R2). In this case, the value of the determination coefficient (R2 = 0.9949) is indicated. Maximum color removal efficiency was achieved at the obtained conditions of: pH = 4, concentration of electrolyte = 3.5 g/L and current density = 19 mA/cm2. Dye removal rate increased by increasing the concentration of electrolyte,lowering pH and increasing the current density. In optimum conditions, decolorization was obtained completely after 5 min; and the removal of chemical oxygen demand (COD) was reduced to 70.3% after 90 min.

Neurologic Complications in Percutaneous Nephrolithotomy

Abbas Basiri,Mohammad Hossein Soltani,Mohammadreza Kamranmanesh,Ali Tabibi,Seyed Amir Mohsen Ziaee,Akbar Nouralizadeh,Farzaneh Sharifiaghdas,Mahtab Poorzamani,Babak Gharaei,Ardalan Ozhand,Alireza Lash 대한비뇨의학회 2013 Investigative and Clinical Urology Vol.54 No.3

Purpose: Percutaneous nephrolithotomy (PCNL) has been the preferred procedure for the removal of large renal stones in Iran since 1990. Recently, we encountered a series of devastating neurologic complications during PCNL, including paraplegia and hemiplegia. There are several reports of neurologic complications following PCNL owing to paradoxical air emboli, but there are no reports of paraplegia following PCNL. Materials and Methods: We retrospectively reviewed the medical records of patients who had undergone PCNL in 13 different endourologic centers and retrieved data related to neurologic complications after PCNL, including coma, paraplegia, hemiplegia,and quadriplegia. Results: The total number of PCNL procedures in these 13 centers was 30,666. Among these procedures, 11 cases were complicated by neurologic events, and four of these cases experienced paraplegia. All events happened with the patient in the prone position with the use of general anesthesia and in the presence of air injection. There were no reports of neurologic complications in PCNL procedures performed with the patient under general anesthesia and in the prone position and with contrast injection. Conclusions: It can be assumed that using room air to opacify the collecting system played a major role in the occurrence of these complications. Likewise, the prone position and general anesthesia may predispose to these events in the presence of air injection.

Ultrasound spray nozzle atomizer as a chemical reaction medium: Evaluation using Villermaux-Dushman test reaction

Mojdeh Basiri,Masoud Rahimi 한국화학공학회 2023 Korean Journal of Chemical Engineering Vol.40 No.5

The present work illustrates the possibility of atomizing the reactant mixture using an ultrasound spray nozzle atomizer to increase reactant contact surface area. The more surface area of the mist-like spray generated due to the atomization provides a means for mixing of reactants, thereby enhancing the reaction rate. Therefore, this work implements an ultrasound spray nozzle atomizer as a reactor. The micromixing efficiency of this novel reactor was evaluated using the Villermaux-Dushman test reaction protocol. An inlet micromixer was placed upstream of the ultrasonic atomizer reactor to provide an early mixing of the reactants. Two simple Y-shaped micromixers with diameters of 0.8 mm and 1.5 mm were examined as the inlet micromixers. The effects of flow rate ratio, flow rate, reactant concentration and inlet micromixer diameter on micromixing efficiency were investigated. Furthermore, the micromixing time was calculated based on the incorporation model through a detailed mathematical formulation. For the studied ranges of operating conditions, the micromixing time was in the range of 0.1–1 s. The small value of estimated micromixing times confirmed that the proposed technique is a valuable concept for intensifying micromixing in chemical reactors.

The histologic features of intratubular germ cell neoplasia and its correlation with tumor behavior

Abbas Basiri,Saeed Movahhed,Mahmood Parvin,Maziar Salimi,Gholam Hossein Rezaeetalab 대한비뇨의학회 2016 Investigative and Clinical Urology Vol.57 No.3

Purpose: To assess the prevalence of intratubular germ cell neoplasia (ITGCN) in patients with concurrent testis tumor and its correlation with histologic features and serum tumor markers. Materials and Methods: From 2003 to 2015, 179 patients underwent radical orchiectomy due to testicular mass. Tissue specimens were evaluated by an expert uro-pathologist using immunohistochemistry (IHC) staining, in addition to light microscopy, to identify presence of ITGCN. Patients' demographic characteristics, histologic subtypes, pathologic stage of tumor and serum tumor markers were gathered and analyzed. Results: Eighty-five out of 179 patients (47.5%) had concomitant ITGCN according to IHC staining. There was not statistically significant difference in histologic type, histologic components, cryptorchidism, and lymphovascular invasion between the 2 groups (p=0.151, p=0.11, p=0.233, p=0.413, and p=0.14, respectively). The prevalence of ITGCN was significantly higher in patients with stage T2 and T3 of tumor than those with stage T1. Elevated serum alpha feto protein level is much common in patients with ITGCN (p<0.001). Conclusions: The prevalence of concurrent ITGCN in our region is lower than previous data from western countries. ITGCN is more common in higher tumor stages and is accompanied with elevated serum alpha feto protein levels before surgery. Presence of ITGCN in adjacent tissue may suggest a negative cancer behavior.

Comparison of minimally invasive surfactant therapy with intubation surfactant administration and extubation for treating preterm infants with respiratory distress syndrome: a randomized clinical trial

Sabzehei Mohammadkazem,Basiri Behnaz,Shokouhi Maryam,Ghahremani Sajad,Moradi Ali 대한소아청소년과학회 2022 Clinical and Experimental Pediatrics (CEP) Vol.65 No.4

Background: Respiratory distress syndrome (RDS) is a common cause of hospitalization and death in preterm infants who require surfactant treatment and respiratory support.Purpose: This study aimed to compare the clinical outcomes of minimally invasive surfactant therapy (MIST) and the INtubation, SURfactant administration, and Extubation (INSURE) technique in preterm infants with RDS.Methods: In this clinical trial, 112 preterm infants born at 28–36 weeks of gestation and diagnosed with RDS randomly received 200-mg/kg surfactant by MIST or the INSURE method. In the MIST group, surfactant was administered using a thin catheter (5F feeding tube); in the INSURE group, surfactant was administered after intubation using a feeding tube and the tracheal tube was removed after positive pressure ventilation was started. Nasal continuous positive airway pressure was applied in both groups for respiratory support and the postprocedure clinical outcomes were compared.Results: The mean hospitalization time was shorter for infants in the MIST group than for those in the INSURE group (9.19± 1.72 days vs. 10.21±2.15 days, P=0.006). Patent ductus arteriosus was less frequent in the MIST group (14.3% vs. 30.4%, P=0.041). Desaturation during surfactant administration occurred less commonly in the MIST group (19.6% vs. 39.3%, P=0.023). There were no significant intergroup differences in other early or late complications.Conclusion: These results suggest that surfactant administration using MIST could be a good replacement for INSURE in preterm infants with RDS since its use reduced the hospitalization time and the number of side effects.