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OSCAR is a collagen receptor that costimulates osteoclastogenesis in DAP12-deficient humans and mice
Barrow, A.D.,Raynal, N.,Andersen, T.L.,Slatter, D.A.,Bihan, D.,Pugh, N.,Cella, M.,Kim, T.,Rho, J.,Negishi-Koga, T. American Society for Clinical Investigation 2011 The Journal of clinical investigation Vol.121 No.9
Ekholuenetale Michael,Barrow Amadou 대한고혈압학회 2020 Clinical Hypertension Vol.26 No.4
Background: Addressing chronic diseases is a challenge for healthcare systems worldwide, which have largely developed to deal with acute episodic care, rather than to provide organized care for people with age-long conditions. Therefore, exploring the prevalence and identifying the risk factors is a major approach to prevention and control of chronic diseases. The aim of this study was to examine the prevalence and factors associated with self-reported high blood pressure among women of reproductive age in Benin. Methods: We utilized population-based cross-sectional data from Benin Demographic and Health Survey (BDHS). BDHS 2017–18 is the round V of the survey. A total of 7712 women of reproductive age were included in this study. The outcome variable was self-reported high blood pressure. Percentages, chi-square test and multivariable logistic regression model were used to analyze the data. Results from the multivariable logistic model were presented as adjusted odds ratio (aOR) and confidence interval (95%CI). The significance level was set at p < 0.05. Results: The total prevalence of self-reported high blood pressure among women of reproductive age in The Gambia was about one-tenth (9.9%). Furthermore, geographical region was associated with high blood pressure. Women aged 45–49 years had increased odds of high blood pressure, when compared with women aged 15–19 years (aOR = 2.73; 95%CI: 1.10, 6.79). In addition, increased maternal enlightenment gave higher odds of high blood pressure, when compared to women with low maternal enlightenment (aOR = 1.41; 95%CI: 1.08, 1.84). Women with highest neighbourhood socioeconomic disadvantaged status (poor women) had 30% reduction in the odds of high blood pressure, when compared with women of low neighbourhood socioeconomic disadvantaged status (aOR = 0.70; 0.50, 0.99). Women having increased lifetime number of sex partners (total of 3 lifetime number of sex partners: aOR = 1.40; 95%CI: 1.01, 1.94; more than 3 total lifetime number of sex partners: aOR = 1.53; 95%CI: 1.01, 2.32) were more likely to have high blood pressure, when compared to women with only one lifetime number of sex partner. Conclusions: Emphasis on high blood pressure prevention methods and involvement of multiple sectors could help to disseminate health care interventions widely. Also, a concerted effort from the stakeholders in health care system and decision-makers is needed to address the drivers of high blood pressure while maintaining health system improvement strategies. The findings could prompt appropriate policy responses towards improving the knowledge and control of high blood pressure in Benin.
Emanuel Schembri,Michelle Barrow,Christopher McKenzie,Andrew Dawson 대한통증학회 2022 The Korean Journal of Pain Vol.35 No.1
Changes in diagnostic criteria, for example, the various International Classification of Headache Disorders criteria, would lead to changes in the outcomes of epidemiological studies. International Classification of Headache Disorders-1 was based mainly on expert opinion, yet most of the diagnostic criteria were reliable and valid, but it did not include chronic migraine. In its second version, the classification introduced chronic migraine, but this diagnosis resembled more a high-frequency migraine rather than the actual migraine transformation process. It also introduced medication overuse headache, but it necessitated analgesic withdrawal and subsequent headache improvement to be diagnosed as such. Hence patients having medication overuse headache could only be diagnosed in retrospect, which was an awkward situation. Such restrictive criteria for chronic migraine and medication overuse headache omitted a high proportion of patients. International Classification of Headache Disorders-3 allows a diagnosis of medication overuse headache due to combination analgesics if taken for at least 10 days per month for more than three months. Hence the prevalence rate of medication overuse headache and chronic migraine can increase compared to the previous version of the headache classification. Different criteria have been used across studies to identify chronic migraine and medication overuse headache, and therefore the information acquired from previous studies using earlier criteria becomes uncertain. Hence much epidemiological research would need to be interpreted cautiously or repeated with the most updated criteria, since the subjects in studies that apply the latest criteria may be phenotypically different from those in older studies.
Surgical Management of Intracranial Aneurysms in the Endovascular Era : Review Article
Mason, Alexander M.,Cawley, C. Michael III,Barrow, Daniel L. The Korean Neurosurgical Society 2009 Journal of Korean neurosurgical society Vol.45 No.3
The advent of endovascular therapy for intracranial aneurysms and the rapid advances in that field have supplanted microsurgical treatment for many intracranial aneurysms. Applying current outcome data and other parameters, nuances of selecting the modality of treatment for intracranial aneurysms are reviewed. Patient factors, such a age, co-morbidities, vasospasm and other medical conditions, are addressed. A custom-tailored multimodality treatment paradigm for the management of ruptured and unruptured aneurysms will maximize the favorable results seen in this difficult patient population.
Indocyanine Green Videoangiography for Confirmation of Bypass Graft Patency
Schuette, Albert J.,Dannenbaum, Mark J.,Cawley, Charles M.,Barrow, Daniel L. The Korean Neurosurgical Society 2011 Journal of Korean neurosurgical society Vol.50 No.1
Objective : The aim of the study is to determine the efficacy of indocyanine green (ICG) videoangiography for confirmation of vascular anastomosis patency in both extracranial-intracranial and intracranial-intracranial bypasses. Methods : Intraoperative ICG videoangiography was used as a surgical adjunct for 56 bypasses in 47 patients to assay the patency of intracranial vascular anastomosis. These patients underwent a bypass for cerebral ischemia in 31 instances and as an adjunct to intracranial aneurysm surgery in 25. After completion of the bypass, ICG was administered to assess the patency of the graft. The findings on ICG videoangiography were then compared to intraoperative and/or postoperative imaging. Results : ICG provided an excellent visualization of all cerebral arteries and grafts at the time of surgery. Four grafts were determined to be suboptimal and were revised at the time of surgery. Findings on ICG videoangiography correlated with intraoperative and/or postoperative imaging. Conclusion : ICG videoangiography is rapid, effective, and reliable in determining the intraoperative patency of bypass grafts. It provides intraoperative information allowing revision to reduce the incidence of technical errors that may lead to early graft thrombosis.
Cho, Yunju,Qi, Yulin,O’Connor, Peter B.,Barrow, Mark P.,Kim, Sunghwan Springer New York LLC 2014 Journal of the American Society for Mass Spectrome Vol.25 No.1
<P>In this study, a phase-correction technique was applied to the study of crude oil spectra obtained using a 7 T Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS). 7 T FT-ICR MS had not been widely used for oil analysis due to the lower resolving power compared with high field FT-ICR MS. For low field instruments, usage of data that has not been phase-corrected results in an inability to resolve critical mass splits of C<SUB>3</SUB> and SH<SUB>4</SUB> (3.4 mDa), and <SUP>13</SUP>C and CH (4.5 mDa). This results in incorrect assignments of molecular formulae, and discontinuous double bond equivalents (DBE) and carbon number distributions of S<SUB>1</SUB>, S<SUB>2</SUB>, and hydrocarbon classes are obtained. Application of phase correction to the same data, however, improves the reliability of assignments and produces continuous DBE and carbon number distributions. Therefore, this study clearly demonstrates that phase correction improves data analysis and the reliability of assignments of molecular formulae in crude oil anlayses.</P> [FIG OMISSION]</BR>
Radiative decays of theΣ0(1385)andΛ(1520)hyperons
Taylor, S.,Mutchler, G. S.,Adams, G.,Ambrozewicz, P.,Anciant, E.,Anghinolfi, M.,Asavapibhop, B.,Asryan, G.,Audit, G.,Avakian, H.,Bagdasaryan, H.,Ball, J. P.,Barrow, S.,Batourine, V.,Battaglieri, M.,Be American Physical Society 2005 PHYSICAL REVIEW C - Vol.71 No.5