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      • A sliding-mode control approach towards design of driving assistance system for lane-change maneuver in connected vehicles

        Uddipan Barooah,Sreelakshmi Manjunath 제어로봇시스템학회 2021 제어로봇시스템학회 국제학술대회 논문집 Vol.2021 No.10

        Advanced driver assistance systems (ADAS) that can assist a human driver in performing complicated maneuvers are known to reduce driver stress, enhance safety, and improve road throughput. We approach the design of ADAS, specifically for lane changing in connected vehicles, from a trajectory tracking perspective. In particular, we design a controller that ensures that the dynamics of the subject vehicle (SV) tracks a reference trajectory for safe lane changing, while avoiding collisions with lead vehicles (LVs) in the current and target lanes. The dynamics of the SV is modelled using the basic kinematic bicycle model. The reference trajectory comprises: (i) the longitudinal trajectory based on the two-lane car-following framework that considers the positions of the two LVs, (ii) the heading angle trajectory based on a logistic growth-decay model which accounts for the lane width and time available for the maneuver, and (iii) the lateral trajectory obtained using the two aforementioned trajectories. A coupled multiple sliding-mode control based controller is designed for trajectory tracking such that the SV traverses along the desired path. Our theoretical results are substantiated with numerical simulations. It is seen that the derived controller tracks the desired trajectories efficiently.

      • Polymorphisms in Heat Shock Proteins A1B and A1L (HOM) as Risk Factors for Oesophageal Carcinoma in Northeast India

        Saikia, Snigdha,Barooah, Prajjalendra,Bhattacharyya, Mallika,Deka, Manab,Goswami, Bhabadev,Sarma, Manash P,Medhi, Subhash Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.18

        Background: To investigate polymorphisms in heat shock proteins A1B and A1L (HOM) and associated risk of oesophageal carcinoma in Northeast India. Materials and Methods: The study includes oesophageal cancer (ECA) patients attending general outpatient department (OPD) and endoscopic unit of Gauhati Medical College. Patients were diagnosed based on endoscopic and histopathological findings. Genomic DNA was typed for HSPA1B1267 and HSPA1L2437 SNPs using the polymerase chain reaction with restriction fragment length polymorphisms. Results: A total of 78 cases and 100 age-sex matched healthy controls were included in the study with a male: female ratio of 5:3 and a mean age of $61.4{\pm}8.5years$. Clinico-pathological evaluation showed 84% had squamous cell carcinoma and 16% were adenocarcinoma. Dysphagia grades 4 (43.5%) and 5 (37.1%) were observed by endoscopic and hispathological evaluation. The frequency of genomic variation of A1B from wild type A/A to heterozygous A/G and mutant G/G showed a positive association [chi sq=19.9, p=<0.05] and the allelic frequency also showed a significant correlation [chi sq=10.3, with cases vs. controls, OR=0.32, $p{\leq}0.05$]. The genomic variation of A1L from wild T/T to heterozygous T/C and mutant C/C were found positively associated [chi sq=7.02, p<0.05] with development of ECA. While analyzing the allelic frequency, there was no significant association [chi sq=3.19, OR=0.49, p=0.07]. Among all the risk factors, betel quid [OR=9.79, Chi square=35.0, p<0.05], tobacco [OR=2.95, chi square=10.6, p<0.05], smoking [OR=3.23, chi square=10.1, p<0.05] demonstrated significant differences between consumers vs. non consumers regarding EC development. Alcohol did not show any significant association [OR=1.34, chi square=0.69, p=0.4] independently. Conclusions: It can be concluded that the present study provides marked evidence that polymorphisms of HSP70 A1B and HSP70 A1L genes are associated with the development of ECA in a population in Northeast India, A1B having a stronger influence. Betel quid consumption was found to be a highly significant risk factor, followed by smoking and tobacco chewing. Although alcohol was not a potent risk factor independently, alcohol consumption along with tobacco, smoking and betel nut was found to contribute to development of ECA.

      • KCI등재

        Effect of Multiparity and Prolonged Lactation on Bone Mineral Density

        ( Nalini Sharma ),( Tanie Natung ),( Rituparna Barooah ),( Santa Singh Ahanthem ) 대한폐경학회 2016 대한폐경학회지 Vol.22 No.3

        Objectives: This study was done to determine the effect of multiparity and prolonged lactation on bone mineral density (BMD). Methods: This cross-sectional study included 196 perimenopausal and postmenopausal women aged 40 to 60 years old. Age, body mass index (BMI), menopausal status, duration of menopause, parity and total duration of lactation, nutritional history were recorded. Lumbar spine (LS; L2-L4) and femur neck (FN) BMD were measured using dual energy X-ray absorptiometry. Correlation of parity and lactation with BMD were investigated using multiple regression analysis. Results: Parity was inversely correlated to BMD for LS (β = -0.266, P = 0.001) and FN (β = -0.380, P = 0.000). This relation remained significant even after adjusting for age, BMI and duration of menopause. Duration of lactation was inversely correlated with BMD for LS (β = -0.271, P = 0.001) but no for FN (β = -0.124, P = 0.130). Conclusions: Multiparity and prolonged lactation have negative impact on BMD especially with in a socioeconomic group whose nutritional intake is borderline. Our data support that parity and duration of lactation can be associated with future osteoporosis. (J Menopausal Med 2016;22:161-166)

      • KCI등재

        Identification and functional properties of dominant lactic acid bacteria isolated from Kahudi, a traditional rapeseed fermented food product of Assam, India

        Gunajit Goswami,Sudipta Sankar Bora,Assma Parveen,Robin Chandra Boro,Madhumita Barooah 한국식품연구원 2017 Journal of Ethnic Foods Vol.4 No.3

        Kahudi or Pani tenga is a very unique fermented mustard product of Assam that is prepared by mixing coarsely ground mustard with extracts of acidic Garcinia pedunculata (Thekera) or tamarind. Kahudi is produced through a spontaneous and uncontrolled solid state fermentation and very little scientific effort has been directed to understand its microflora and their functional properties. In this paper, we report the microbial flora and their dynamics during Kahudi fermentation with special emphasis on lactic acid bacteria (LAB). LAB were found to be dominant (8 log CFU/g) over other microbial flora (4 log CFU/g) during the fermentation process leading to Kahudi formation. The microbial load in Kahudi did not include any mycelial molds or pathogenic enteric bacteria. Combination of phenotypic parameters, biochemical tests, and 16S rDNA gene sequencing revealed the dominant group of LAB as Enterococcus durans, Lactobacillus plantarum, Lactobacillus fermentum, and Lactobacillus casei. The sugar fermentation and enzyme profile analysis revealed the ability of the microbial consortia to metabolize an array of indigestible sugars including D-mannose, mannitol, sorbitol, methyl-α-D-mannopyranoside, methyl-α-D-glucopyranoside, N-acetylglucosamine, amygdalin, and arbutin. Although the isolates showed good acid phosphatase activity they had weak extracellular phytase activity. This is the first report on the microbial dynamics and involvement of LAB during Kahudi fermentation.

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